XLOC_012931 (kcnab1a)


Basic Information

Item Value
gene id XLOC_012931
gene name kcnab1a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007129.7
NCBI id CM002902.2
chromosome length 51023478
location 34362608 ~ 34536067 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00025765
TCAGTGCTGCGGGAATCTCCTCTCCACCTCCTCTGGATAGTTCTGCAGCTCTCGTTTTGTGGCTCATTGATCCGGGTGCAGTTTTGACAGTTGTCTTTTCCCAAGGGAACGTCTTGGACAAGGAGCCACACAACTTTCGGACTGTGTAGACGTCTCCTTTTTCTTTTGCGCTTAATAATTGATGGTGTTCCTCCACTGCTGCTTCAAAGGTATCCACAGGACAGGATCAAAGCGGAAAGTTGGGACTGTGACCCCCACATGATCCCTCAGTGTGTCCTCTTTGTGTTGTACACTGCATCTCCTTCATCCTCCTAATTCAGAATGCAGGTTTCAATCGCTTGCACGGACCACAATCTGAAGGGTCGGAATGGGGATCACGGGAAAACTAATGCCACCAGTCCCAATGTGGTGAATGCAGCACGGGCAAAGTTCCGTACAGTTGCCATCATCGCTCGGAGCTTTGGCTCTTTCACCCCACGCCATCACATCTCCCTTAAAGAGTCCACCGGCAAGCTCACTGGCATGAAGTACCGGAACCTTGGGAAATCTGGATTGAGAGTATCATGCCTTGGTCTGGGCACTTGGGTGACATTTGGAGGGCAGATTTCAGATGATGTTGCTGAGCAGCTGATGACTATAGCGTATGAGAGCGGGGTGAATCTGTTTGACACTGCAGAGGTGTACGCTGCTGGAAAAGCTGAAGTCATACTGGGAAACATCATCAAAAAGAAGGGCTGGAGGCGGTCCAGTCTGGTTATTACCACAAAGCTCTACTGGGGTGGAAAAGCTGAGACTGAACGAGGCCTTTCTAGGAAGCACATTATTGAAGGTCTCAAGGGCTCCTTGCAGAGGATGCAGATGGAGTATGTGGATGTAGTCTTTGCCAACCGGCCTGATAGCAATACACCAATGGAAGAGATTGTCAGAGCCATGACCTACGTGATAAACCAAGGCATGTCCATGTACTGGGGGACTTCACGATGGACAGCAATGGAAATAATGgAGGCATATTCTGTGGCAAGACAGTTTAACCTGATTCCTCCAGTGTGTGAGCAGGCCGAGTATCATCTGTTCCAGAGGGAGAAGGTTGAGGTGCAGCTGCCGGAGCTCTACCATAAGATAGGTGTCGGTGCCATGACATGGTCACCTTTGGCTTGTGGGATCATTACTGGAAAGTATGAAAACGGTATCCCAGACTCCTCCAGAGCATCTATGAAGTCATACCAGTGGCTGAAAGAGAAGATAGTCAGCGAGGATGGACGCAAGCAGCAGGCGAAGCTGAAAGAACTGGGTCACATTGCAGAGAAGCTGGGCTGCACTTTGCCTCAGCTCGCCGTAGCCTGGTGTCTGAGGAATGAGGGAGTGAGTTCAGTGCTATTAGGAACCTCCAATGCAGAACAGCTAACTGAAAACCTGGGAGCCATACAGGTACTTCCAAAGATGACGTCTCATGTGGTCTCAGACATTGATCATATACTTGGGAACAAGCCCTACAGTAAGAAGGACTATCGTTCCTAGATGCTACGGACACACGCTCAGGGTCAAGAGAGAAGTGTGTGTAGCAGTGTTCGTGCCCTAGTGGTTCCTGCTCCGAATCTGTTTTCATCATTGGcctgacctctctctctctctctctctctctgaagccTTAGAGCGCCGTCCTCCATTACCATACCTCCATTCCCTCTGTTTTTGCTGGTGTGCCTTTGCACCCCAAAACCACAGCAAGAATCCTCACGACTGGTGTTCAGGTGTCTTCTCGTAATGGCACCTTACTGGAGGAGAGCTTCACTTGCTGATGTGATCTATGAAGCGCATAAACACCCATGCTCCATGTCTGGCCTCCGCTCTCAAAACCATCAGCCATCGGATCGTCTGGTGGTTTTAGCACGCATACTGGAGGAACAGAGCATGACGCCCTCTTGTGCTCAAACGCAGCAACTGCAGAGCTGTTTCACAGACTGATGAGCTTCTACTCAGTGGAACAATGCACATTCACAAAGATCTAAGCTGTTCTGCCTGTGCAAGAATGCCTGTATAGATATTTTATGAGGGGGTTTTATTTTAAGAGTTATTTGCTTCATAGTGTGGGCCACAGTGATGTGTGgtagaaaaataaatgcacactTTTGACCTAGGAAATTACTTGAATGAGGGTAGCATACACCTATGAATATCTGCTTATTGAACATGCAGCTGTATTATAAACTGACCTCAATCCCTACTGCAGTATATAAGTATACAGTATTAGAGTTGATCTAACATGCATAGACTATGTTATGCCAGCAACCTAAGCATTCATGATGCTTTATTATAAATAAGTGACTTGGTTTTGCTTTGGGTacaattaaaaaa
>TCONS_00025766
AGGCACTTGGGTGACATTTGGAGGGCAGATTTCAGATGATGTTGCTGAGCAGCTGATGACTATAGCGTATGAGAGCGGGGTGAATCTGTTTGACACTGCAGAGGTGTACGCTGCTGGAAAAGCTGAAGTCATACTGGGAAACATCATCAAAAAGAAGGGCTGGAGGCGGTCCAGTCTGGTTATTACCACAAAGCTCTACTGGGGTGGAAAAGCTGAGACTGAACGAGGCCTTTCTAGGAAGCACATTATTGAAGGTCTCAAGGGCTCCTTGCAGAGGATGCAGATGGAGTATGTGGATGTAGTCTTTGCCAACCGGCCTGATAGCAATACACCAATGGAAGAGATTGTCAGAGCCATGACCTACGTGATAAACCAAGGCATGTCCATGTACTGGGGGACTTCACGATGGACAGCAATGGAAATAATGgAGGCATATTCTGTGGCAAGACAGTTTAACCTGATTCCTCCAGTGTGTGAGCAGGCCGAGTATCATCTGTTCCAGAGGGAGAAGGTTGAGGTGCAGCTGCCGGAGCTCTACCATAAGATAGGTGTCGGTGCCATGACATGGTCACCTTTGGCTTGTGGGATCATTACTGGAAAGTATGAAAACGGTATCCCAGACTCCTCCAGAGCATCTATGAAGTCATACCAGTGGCTGAAAGAGAAGATAGTCAGCGAGGATGGACGCAAGCAGCAGGCGAAGCTGAAAGAACTGGGTCACATTGCAGAGAAGCTGGGCTGCACTTTGCCTCAGCTCGCCGTAGCCTGGTGTCTGAGGAATGAGGGAGTGAGTTCAGTGCTATTAGGAACCTCCAATGCAGAACAGCTAACTGAAAACCTGGGAGCCATACAGGTACTTCCAAAGATGACGTCTCATGTGGTCTCAGACATTGATCATATACTTGGGAACAAGCCCTACAGTAAGAAGGACTATCGTTCCTAGATGCTACGGACACACGCTCAGGGTCAAGAGAGAAGTGTGTGTAGCAGTGTTCGTGCCCTAGTGGTTCCTGCTCCGAATCTGTTTTCATCATTGGcctgacctctctctctctctctctctctctgaagccTTAGAGCGCCGTCCTCCATTACCATACCTCCATTCCCTCTGTTTTTGCTGGTGTGCCTTTGCACCCCAAAACCACAGCAAGAATCCTCACGACTGGTGTTCAGGTGTCTTCTCGTAATGGCACCTTACTGGAGGAGAGCTTCACTTGCTGATGTGATCTATGAAGCGCATAAACACCCATGCTCCATGTCTGGCCTCCGCTCTCAAAACCATCAGCCATCGGATCGTCTGGTGGTTTTAGCACGCATACTGGAGGAACAGAGCATGACGCCCTCTTGTGCTCAAACGCAGCAACTGCAGAGCTGTTTCACAGACTGATGAGCTTCTACTCAGTGGAACAATGCACATTCACAAAGATCTAAGCTGTTCTGCCTGTGCAAGAATGCCTGTATAGATATTTTATGAGGGGGTTTTATTTTAAGAGTTATTTGCTTCATAGTGTGGGCCACAGTGATGTGTGgtagaaaaataaatgcacactTTTGACCTAGGAAATTACTTGAATGAGGGTAGCATACACCTATGAATATCTGCTTATTGAACATGCAGCTGTATTATAAACTGACCTCAATCCCTACTGCAGTATATAAGTATACAGTATTAGAGTTGATCTAACATGCATAGACTATGTTATGCCAGCAACCTAAGCATTCATGATGCTTTATTATAAATAAGTGACTTGGTTTTGCTTTGGGTacaattaaaaaaggaaattagaAGAGGACAACTTAAAGGGATGCCCTTGTGAAAAAGAAGTGTGTCTGATTGTAATGAATCTGCACTTGTTAGTTTAAGATAACATAAAGGCACTTATGTGTGCTTAAAGGGAGTTCACTTTCATGAATAAGTTTCTCTATACATTGTTGTACTTTCAAAAAGTCAATGGAAAAGATTTGCTTTGATGAATATATTAATTCATTGTGGTTTTATAATCTGTTGTCAtgctttaaagcagtggttcccaatcTGTTTTTTTGCCTGAGTATCCCTTATCCCCTGGAAAATGATGCAAGGCCCTTGTAAGGTAACATTTAATGATAGTATCGCTCAAATATGTTTGCAGTAAGGATGACAAAaactgttgttttcaaacaaacagtatgtttattactatataatattaataaacttgaatttgaattttattactttgaattttaatttcttttttaaatacttcccaaatgatgtcttacatagc

Function

symbol description
kcnab1a Predicted to enable aldo-keto reductase (NADP) activity; potassium channel regulator activity; and transmembrane transporter binding activity. Predicted to be involved in negative regulation of delayed rectifier potassium channel activity. Predicted to act upstream of or within potassium ion transport; regulation of ion transmembrane transport; and transmembrane transport. Predicted to be located in cytoplasm and plasma membrane. Predicted to be integral component of membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in juxtaparanode region of axon. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Is expressed in immature eye; myotome; nervous system; pharyngeal arch; and somite. Human ortholog(s) of this gene implicated in temporal lobe epilepsy. Orthologous to human KCNAB1 (potassium voltage-gated channel subfamily A regulatory beta subunit 1).

GO:

id name namespace
GO:0055085 transmembrane transport biological_process
GO:1901379 regulation of potassium ion transmembrane transport biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0006813 potassium ion transport biological_process
GO:1902260 negative regulation of delayed rectifier potassium channel activity biological_process
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane cellular_component
GO:0044224 juxtaparanode region of axon cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0008076 voltage-gated potassium channel complex cellular_component
GO:0005737 cytoplasm cellular_component
GO:0004033 aldo-keto reductase (NADP) activity molecular_function
GO:0005249 voltage-gated potassium channel activity molecular_function
GO:0044325 ion channel binding molecular_function
GO:0015459 potassium channel regulator activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-050327-79 Predicted to enable aldo-keto reductase (NADP) activity; potassium channel regulator activity; and transmembrane transporter binding activity. Predicted to be involved in negative regulation of delayed rectifier potassium channel activity. Predicted to act upstream of or within potassium ion transport; regulation of ion transmembrane transport; and transmembrane transport. Predicted to be located in cytoplasm and plasma membrane. Predicted to be integral component of membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in juxtaparanode region of axon. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Is expressed in immature eye; myotome; nervous system; pharyngeal arch; and somite. Human ortholog(s) of this gene implicated in temporal lobe epilepsy. Orthologous to human KCNAB1 (potassium voltage-gated channel subfamily A regulatory beta subunit 1).

Ensembl:

ensembl_id ENSDARG00000008140

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00025765 False 2355 mRNA 0.48 14 34362608 34535574
TCONS_00025766 True 2273 mRNA 0.43 12 34478959 34536067

Neighbor

gene id symbol gene type direction distance location
XLOC_012930 vmn2r1 coding upstream 120050 34225520 ~ 34242558 (+)
XLOC_012929 gmps coding upstream 145722 34181655 ~ 34216886 (+)
XLOC_012928 NA coding upstream 313941 34028272 ~ 34048667 (+)
XLOC_012927 olfcq20 coding upstream 444252 33914168 ~ 33918356 (+)
XLOC_012926 olfcq19 coding upstream 540717 33818577 ~ 33821891 (+)
XLOC_012932 tiparp coding downstream 63248 34599315 ~ 34642086 (+)
XLOC_012933 CR626874.1 coding downstream 131419 34667486 ~ 34836808 (+)
XLOC_012934 LO018333.1 coding downstream 325501 34861568 ~ 34935178 (+)
XLOC_012935 NA coding downstream 406661 34942728 ~ 35038409 (+)
XLOC_012936 AL935279.1 coding downstream 536909 35072976 ~ 35074637 (+)
XLOC_012923 CU463109.2 non-coding upstream 615493 33735335 ~ 33747115 (+)
XLOC_012922 NA non-coding upstream 630993 33725576 ~ 33731615 (+)
XLOC_012918 CR405715.1 non-coding upstream 735758 33622917 ~ 33626850 (+)
XLOC_012909 BX649633.1 non-coding upstream 918351 33443264 ~ 33444257 (+)
XLOC_012937 NA non-coding downstream 539348 35075415 ~ 35075774 (+)
XLOC_012942 NA non-coding downstream 894939 35431006 ~ 35431848 (+)
XLOC_012944 CR377223.1 non-coding downstream 1270781 35806848 ~ 35806966 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000180_00271959_00298820 KCNAB1A, KCNAB1B, KCNAB1 coding CI01000180 null 271610 ~ 299150 (+)