XLOC_015510 (ptf1a)


Basic Information

Item Value
gene id XLOC_015510
gene name ptf1a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007113.7
NCBI id CM002886.2
chromosome length 59640629
location 29710857 ~ 29711761 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00031012
ATGGACACTGTGTTGGATCCATTCACAGGCTTAGACTCTTTCTCCTCCTCTTATTTCGACGACGATGACTTCTTTACGGACCACTCTTCGAGAGACCACTTGGACACAGACGACTTTCTGGACGAGGATGTCGATTTTCTTACCAACCAAATTCAAGAATATTACAAGGATAGTCGGATATCACAGGACGGAGATTATTGTGACGTTGGCAACTTCTCCTTTTCCTCGTCATCTTCGACTTTTTCTTACGGATGCGCGGACAGCACCTCAGAGCTGTCCCCTCACAGAGACGGAGGCTTACTGAAGAGGCGGAGGCGCATGAGGTCTGAAGTGGAGATGCAACAGTTGCGTCAAGCTGCCAACGTCCGGGAGCGACGGAGGATGCAGTCCATTAACGATGCTTTCGAGGGACTGCGATCTCACATCCCAACACTGCCATACGAGAAGAGACTTTCAAAAGTTGACACTTTACGCCTAGCAATTGGCTACATAAACTTTCTTGCGGAACTGGTGCAGTCGGACATGCCAATTCGGAATCCACACAGTGACGCCTTAAACCAACCGAAAAAAGTCATCATTTGCCACCGAGGAACAAgaTCCCCATCTCCAAATGACCCAGACTACGGGTTGCCTCCTCTCGCAGGACACTCTCTTTCATGGACTGATGAGAAGCAGTTAAAAGACCAGAATATCATTCGGACAGCGAAAGTCTGGACACCAGAGGACCCACGAAAGTTGCACTTGAAATCATCAATAAACAATATTGAGAATGAACCCCCCTTTAATTTCATTTCCTAA

Function

symbol description
ptf1a Enables DNA-binding transcription factor activity and sequence-specific DNA binding activity. Acts upstream of or within animal organ development and positive regulation of transcription, DNA-templated. Predicted to be located in cytoplasm and nucleus. Predicted to be part of transcription regulator complex. Is expressed in several structures, including exocrine cell; intestinal bulb primordium; mid intestine; nervous system; and pancreatic system. Human ortholog(s) of this gene implicated in pancreatic agenesis. Orthologous to human PTF1A (pancreas associated transcription factor 1a).

GO:

id name namespace
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0006357 regulation of transcription by RNA polymerase II biological_process
GO:0030154 cell differentiation biological_process
GO:0031016 pancreas development biological_process
GO:0031017 exocrine pancreas development biological_process
GO:0009887 animal organ morphogenesis biological_process
GO:0009888 tissue development biological_process
GO:0035881 amacrine cell differentiation biological_process
GO:0045893 positive regulation of transcription, DNA-templated biological_process
GO:0032502 developmental process biological_process
GO:0048384 retinoic acid receptor signaling pathway biological_process
GO:0030902 hindbrain development biological_process
GO:0048699 generation of neurons biological_process
GO:0005634 nucleus cellular_component
GO:0005667 transcription regulator complex cellular_component
GO:0005737 cytoplasm cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding molecular_function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function
GO:0046983 protein dimerization activity molecular_function

KEGG:

id description
ko03000 Transcription factors

ZFIN:

id description
ZDB-GENE-030616-579 Enables DNA-binding transcription factor activity and sequence-specific DNA binding activity. Acts upstream of or within animal organ development and positive regulation of transcription, DNA-templated. Predicted to be located in cytoplasm and nucleus. Predicted to be part of transcription regulator complex. Is expressed in several structures, including exocrine cell; intestinal bulb primordium; mid intestine; nervous system; and pancreatic system. Human ortholog(s) of this gene implicated in pancreatic agenesis. Orthologous to human PTF1A (pancreas associated transcription factor 1a).

Ensembl:

ensembl_id ENSDARG00000014479

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00031012 True 798 mRNA 0.48 2 29710857 29711761

Neighbor

gene id symbol gene type direction distance location
XLOC_015509 dlgap1a coding upstream 18032 29491314 ~ 29692825 (+)
XLOC_015508 cdh18a coding upstream 357678 29249204 ~ 29353179 (+)
XLOC_015507 cdh12a coding upstream 593965 28995776 ~ 29116892 (+)
XLOC_015506 cdh10a coding upstream 776573 28889936 ~ 28934284 (+)
XLOC_015505 nadsyn1 coding upstream 1017929 28672152 ~ 28692928 (+)
XLOC_015511 NA coding downstream 449 29712210 ~ 29727457 (+)
XLOC_015512 si:ch211-207d6.2 coding downstream 84072 29795833 ~ 29896572 (+)
XLOC_015513 htr5aa coding downstream 213800 29925561 ~ 29940519 (+)
XLOC_015514 en2b coding downstream 264658 29976419 ~ 29979956 (+)
XLOC_015515 rbm33b coding downstream 283829 29995590 ~ 30047637 (+)
XLOC_015503 NA non-coding upstream 1287370 28393943 ~ 28423487 (+)
XLOC_015502 NA non-coding upstream 1360410 28245460 ~ 28350447 (+)
XLOC_015501 NA non-coding upstream 1516249 28194138 ~ 28194608 (+)
XLOC_015500 CR925777.1 non-coding upstream 1672232 27975554 ~ 28038625 (+)
XLOC_015489 BX649522.1 non-coding upstream 2386676 27321014 ~ 27324181 (+)
XLOC_015516 NA non-coding downstream 360918 30072679 ~ 30089989 (+)
XLOC_015518 BX510360.1 non-coding downstream 414653 30126414 ~ 30126936 (+)
XLOC_015521 NA non-coding downstream 485609 30197370 ~ 30197741 (+)
XLOC_015523 CR788254.2 non-coding downstream 557545 30269306 ~ 30270163 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location