XLOC_017477 (mcm3)


Basic Information

Item Value
gene id XLOC_017477
gene name mcm3
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007131.7
NCBI id CM002904.2
chromosome length 55201332
location 34770197 ~ 34783743 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00034731
AGATTCCACTGCGAGAGAAGTCTGGTGGCGCGAAAAGGCACACAACAGTGCTGCGACAGACACGAGGTGTTCTGCACTGAACTTTTCTCCATACTTTTAAAAGATCTGTAGCAAAAATGGCTGCTGAAGTTGTGGACGATCAGGAAATGAGGGAGGCTCAGAGGGATTACTTGGATTTTCTTGACGACGACCAAGACCAGGGCATCTACCAGAGCAAAGTACGGCAGATGATCAGCGAAAACAAATCCAGGCTCATTGTAAACCTCAACGACCTGCGACGACGAAATGAAAAGCGAGCAGCAAAGCTGTTGAATAACGCTTTTGAAGAGCTCCTGGCATTCCAGCGAGCCCTGAAAGATCTGGTGGCTTCAATAGATGCCACTTACGCCAAGCAATGTGAGGAGTTCTTCATTGGTTTGGAGGGCAGCTTTGGCAGCAAACATGTCTCCCCTCGAACCCTGACCTCTCGCCTGCTGGGCAGCATGGTGTGTTTGGAGGGCATCGTCACTAAATGCTCTTTGGTGCGTCCCAAAGTAGTACGCAGTGTGCACTACTGTCCAGCCACTAAAAAGACCATGGAGCGCAAATACACCGATTTGACTTCTCTGGATGCCTTCCCTTCAAGTGCCATTTACCCCACCAAGGATGAAGAGAACAATCCATTGGAGACAGAGTttggtctgtctgtctataaGGACCaccaaaccatcactatacaggAGATGCCGGAGAAGGCCCCTGCTGGTCAGCTGCCCCGCTCTGTGGACATCATCCTGGACAATGACCTGGTGGACGCCGTGAAGCCTGGAGACCGAACACAGGTGATCGGCACCTACCGCTGCCTGCCGGGCAAGAAGGGTGGCTTCACCTCGGGCACCTTCAGGACCATCATGATTGCCTGCCATGTCAAACAGATGAGCAAAGAAATTTCCCACTACTTCTCTGCGGATGATGTGGCCAAAATCAAGAGCTTCTGCAGGTCTCGCTCTAAGAATGTGTTTGATCAGTTGGCTCGCTCTCTGGCCCCCAGTATTCACGGTCATGAGTACATAAAGAAGGCCATCCTGTGCATGCTTCTAGGAGGAGTGGAGAAGGTGCTGGAGAACGGTTCGCGTATTCGAGGAGACATTAACGTGCTTCTCATAGGTGACCCATCAGTGGCCAAGTCTCAGTTGCTCCGGTACGTTCTTCACACTGCTCCTCGGGCCATTCCCACAACAGGCCGTGGTTCATCAGGTGTGGGTCTGACCGCAGCCGTCACCACTGACCAGGAGACAGGCGAGCGGCGTCTGGAAGCTGGGGCCATGGTTTTGGGGGATCGAGGCGTTGTCTGCATTGACGAGTTCGACAAAATGTCAGATATGGATCGCACTGCTATACATGAAGTCATGGAGCAGGGCCGAGTCACCATCGCTAAAGCTGGCATCCACGCTAGACTTAATGCCCGCTGCAGCGTCCTGGCAGCTGCCAACCCCGTCTACGGCAGATATGATCAGTATAAGACACCCATGGAGAACATCGGTCTGCAGGACTCTCTGCTGTCTCGTTTTGATCTGCTCTTCATCATGCTGGATCAGATGGACCCTGAGCAGGACCGCGAGATCTCGGACCACGTGCTGCGTATGCACCGCTACAGAGATCCACATGAGCAGGACGGGACAGCTCTTGCTCTTGGTGGTACAATCGATGCTTTGGCCACGGAAGACCCTGATGCTAcgcaggaggaggaagaggagctcCAGGTTTACGAGAAACACAATCCACTCCTCCACGGCAGCAAAAAAAACAAggATCGAGTAGTGAGCAAAGCCTTCATGAGGAAGTACATCCATGTCGCCAAAGCCATTTCTCCAGTTTTGACCCAAGATGCAGCCAATCACATCGCAGAGGAATATTCACGACTGCGCAACCAGGAGCAGCTGGGCTCCGACATCGCACGGACGTCACCGGTCACTGCCCGAACCCTGGAGACTTTGATCCGTCTGTCCACGGCTCACGCTAAAGCCCGCATGAGTAAAGCTGTGGAGCTGGTGGACACTGAAGTCGCCGTGGAGCTCGTGCAGTTCGCTTATTTCAAGAAGGTTTTGGAGAAGGAACGTAAACGCTCTAGAAATGGACAGCAGGATGCTGCTTCAGAAGACGAGGAAGAAGAGGAAGATGAAGCTCAAGACACACCACGACCACCCAGAAAAAGGCGCAGGGGATCTCAGGGAAGCGAGTCTTATGACCCCTATGACTTCAACACTGAGACTGATATTCCACAGAtTCAGTCTCCGGCTCCTGCGTTGCAGGCTGATGAAGAGCCTGATCAGAATGGCCACACAGAGTTGTCTGAGGACAGGTTTAAGGAGTTTAAAGCGGCTCTGCATAAGGTTTTCCGCTCTTCTCACGCTCAGTCGGTGGGTTTGATTGCTCTGATGGAGAGCATCAACAAGTCTTGCCCATCAGCGTTTAATGAAACAGACTTCCGGGCTGCTCTCGCGCGCATGCAGGACGACAACCAGGTCATGCTGGCTGATGACATCATCTTCCTGATTTAAACATCTTTTCTGGACAATATCAGTGATCCTCCTGTTCTTGCATTCATCTGTTTCAGAAGATCTGCAAtatgtttgctttgtttattacCATACTGTTGCAAGCATTTCTAAAACTAACTCTCTTCAACATTGACAGTAAATTGTTTGCTGTCTATTATTTTTCGCATGCTCATCTATGCGAATATTGGCATTCAATGAAAAAATAACTAGGTTGTATTTTTGCCAAGAAATGatagtttctttttatttctaaacagGCATGTTTCATGTTTTTCAACATACTCAAACCTGGCTTATGTTCTACAGAAATGAGCTTTCTGGTTGTATTTCTTCCTTTATTAAatggttgttttttgttttattaatggcttgtaaatacagatgtttttaaaTACAGATGTTCCAAactaagaaaaaatacaaattcagAAAAATGATAATGGTCAACATTTGTTTTCTGTACTTATTCCAATATTTCTTGTCTAGTCTGTTGCCTTTGTCAATAAAATTGTCAAAAATGAA

Function

symbol description
mcm3 Enables chromatin binding activity. Acts upstream of or within retina development in camera-type eye. Predicted to be located in chromosome. Predicted to be part of MCM complex. Predicted to be active in nucleus. Is expressed in several structures, including alar plate midbrain region; blood; immature eye; nervous system; and pectoral fin musculature. Orthologous to human MCM3 (minichromosome maintenance complex component 3).

GO:

id name namespace
GO:1902975 mitotic DNA replication initiation biological_process
GO:0000727 double-strand break repair via break-induced replication biological_process
GO:0006260 DNA replication biological_process
GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication biological_process
GO:0006270 DNA replication initiation biological_process
GO:0006271 DNA strand elongation involved in DNA replication biological_process
GO:0060041 retina development in camera-type eye biological_process
GO:0042555 MCM complex cellular_component
GO:0005634 nucleus cellular_component
GO:0005524 ATP binding molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0003677 DNA binding molecular_function
GO:0003678 DNA helicase activity molecular_function
GO:0003682 chromatin binding molecular_function
GO:0003688 DNA replication origin binding molecular_function
GO:0003697 single-stranded DNA binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0004386 helicase activity molecular_function

KEGG:

id description
ko03030 DNA replication
ko04110 Cell cycle
ko04111 Cell cycle - yeast
ko04113 Meiosis - yeast
ko03032 DNA replication proteins
ko03036 Chromosome and associated proteins

ZFIN:

id description
ZDB-GENE-020419-4 Enables chromatin binding activity. Acts upstream of or within retina development in camera-type eye. Predicted to be located in chromosome. Predicted to be part of MCM complex. Predicted to be active in nucleus. Is expressed in several structures, including alar plate midbrain region; blood; immature eye; nervous system; and pectoral fin musculature. Orthologous to human MCM3 (minichromosome maintenance complex component 3).

Ensembl:

ensembl_id ENSDARG00000024204

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00034731 True 3062 mRNA 0.49 17 34770197 34783743

Neighbor

gene id symbol gene type direction distance location
XLOC_017475 NA coding upstream 3754 34761743 ~ 34766443 (+)
XLOC_017476 NA coding upstream 4380 34764450 ~ 34765817 (+)
XLOC_017474 pnocb coding upstream 36175 34717403 ~ 34734022 (+)
XLOC_017473 elp3 coding upstream 69543 34671386 ~ 34700654 (+)
XLOC_017472 BX279523.3 coding upstream 105435 34663322 ~ 34664762 (+)
XLOC_017478 il17a/f3 coding downstream 8423 34792166 ~ 34794465 (+)
XLOC_017479 emilin1a coding downstream 61929 34845672 ~ 34865031 (+)
XLOC_017480 ankef1a coding downstream 85190 34868933 ~ 34902205 (+)
XLOC_017481 snap25a coding downstream 129326 34913069 ~ 34956230 (+)
XLOC_017482 NA coding downstream 178411 34962154 ~ 34965993 (+)
XLOC_017471 BX279523.2 non-coding upstream 106999 34661555 ~ 34663198 (+)
XLOC_017455 BX296562.2 non-coding upstream 794905 33959570 ~ 33975292 (+)
XLOC_017483 BX470246.1 non-coding downstream 201380 34985123 ~ 34985782 (+)
XLOC_017484 NA non-coding downstream 228891 35012634 ~ 35014502 (+)
XLOC_017489 BX511024.1 non-coding downstream 598695 35382438 ~ 35429737 (+)
XLOC_017490 BX510920.1 non-coding downstream 638955 35422698 ~ 35422827 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000325_10077265_10086696 MCM3 coding CI01000325 null 10077265 ~ 10087272 (+)
bowfin (Amia calva) AMCG00003720 mcm3 coding CM030121.1 CM030121.1 16258454 ~ 16265698 (+)