XLOC_021644 (kcnab2b)


Basic Information

Item Value
gene id XLOC_021644
gene name kcnab2b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007134.7
NCBI id CM002907.2
chromosome length 46223584
location 21067389 ~ 21114732 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00042958
acacatacacatgaaaCACTTACTTACACACACTTCACACAGACGCCACATGGACAGATACACTCTCAGGCATTCTCACTTCAGAGCGAAATCTGCACTTCTGGTTCAAACAGAGGGCTGCATTCAGCTTTTTGACAGCTTCCACATCCATTTTGACCTTTTTTAGCAGTGTTTTCTTCAAGTTTATTTGGCACTTGGGGCAGAAAGACACTTTGGTACTGCTGGGAGATTTTTGGACTAGTTCTTGCTTGTATCATCAGCATCTTTGAAGTGGTTTGGTTGGCTCGGCATCAGCATGCAGGTGTCTTTTGTGTGCACGGACCATCGAGCCGTCAGCCGGAGCACAGAGGACCGACTGAACCGCCAGAACACCAACAGCCCGAGTTTGGGGACAAAAAGCAAGTTTCGGGCTGTGGCGATGGTGGCCCGCAGTTTGGGCCAGTTGTCTGTGCAGAACATGCCCTCCGCTGGAGACCACTGCTTGAAAACTGGCATGAAATATAGgAACCTCGGGAAATCTGGCTTACGGGTATCATGTCTAGGGCTGGGGACTTGGGTAACTTTTGGTGGACAAATCACTGATGAGATTGCTGAGCAGCTGATGACGCTGGCGTATGAGAACGGCATCAATCTGTTTGACACCGCTGAGGTGTACGCGGCAGGGAAGGCTGAAATGGTCCTCGGCAGTATCATCAAGAAGAAAGGATGGAGACGTTCCAGTTTGGTCATCACCACAAAAATTTACTGGGGTGGAAAagCAGAAACAGAGAGAGGCCTATCTAGAAAACACATCATAGAGGGTCTAAGGGCATCACTGGAGAGACTTCAGTTAGAATATGTGGATGTAGTGTTTGCTAACAGACCTGACCCCAACACGCCAATGGAAGGAGATCCATTTAACACTTCAAAATCAAGAACATTCATCATAGAAGAGACGGTTCGAGCAATGACGCATGTGATAAACCAGGGTATGGCTATGTACTGGGGGACATCCCGCTGGAGCTCCATGGAGATTATGgaaGCGTATTCAGTGGCTCGACAGTTCAATCTGATCCCTCCTGTCTGTGAGCAGGCCGAATATCACATGTTTCAGAGAGAGAAGGTGGAAGTACAGCTGCCTGAACTCTTCCATAAGataggtgtgtgtgtgGTGTGGGTGCCATGACGTGGTCTCCACTGGCGTGTGGCATCATCTCAGGGAAGTATGACAGTGGTGTGCCTCCTTGTTCCAGAGCCTCCCTCAAGGGCTACCAGTGGATGAAGGACAAGATCCTGAGTGAGGAAGGCCGCCGTCAGCAGGCGAAGCTGAAAGAGTTGCAGGCCATTGCGGAGCGGCTGGGCTGCACACTGCCTCAGCTGGCCATCGctTGGTGTCTGAGGAACGAGGGTGTGAGTTGTGTTTTGCTGGGGGCGTCCAGCACCGATCAGCTCATGGAGAACATTGGAGCAATTCAGgtTCTTCCAAAATTATCGTCCTCGATTATACATGAAGTGGACAGTATCCTAGGCAACAAGCCCTACAGTAAAAAGGACTATCGGTCCTAATAGAAAAGTCAATAATGGCACTGTGTCAACCTGCTTCTCTCTCTGAGCTTTGACTGAACTAAACATTGGCACACAGGACCAGCACTGTCACCGGTCCTGCAGGAGACGCCAAACCGCACACTACCTGGAGCCTGAGAAGAGCCTACAGCGCACAGGCATAGGGAAAGCATGCTCACGAACAAATACAGCTCGAACCGGCTGAATATGCAGAATGCCGCTCCAAAAACACCACCAAAAAAAAA
>TCONS_00042959
ATGCAGGTGTCTTTTGTGTGCACGGACCATCGAGCCGTCAGCCGGAGCACAGAGGACCGACTGAACCGCCAGAACACCAACAGCCCGAGTTTGGGGACAAAAAGCAAGTTTCGGGCTGTGGCGATGGTGGCCCGCAGTTTGGGCCAGTTGTCTGTGCAGAACATGCCCTCCGCTGGAGACCACTGCTTGAAAACTGGCATGAAATATAGgAACCTCGGGAAATCTGGCTTACGGGTATCATGTCTAGGGCTGGGGACTTGGGTAACTTTTGGTGGACAAATCACTGATGAGATTGCTGAGCAGCTGATGACGCTGGCGTATGAGAACGGCATCAATCTGTTTGACACCGCTGAGGTGTACGCGGCAGGGAAGGCTGAAATGGTCCTCGGCAGTATCATCAAGAAGAAAGGATGGAGACGTTCCAGTTTGGTCATCACCACAAAAATTTACTGGGGTGGAAAagCAGAAACAGAGAGAGGCCTATCTAGAAAACACATCATAGAGGGTCTAAGGGCATCACTGGAGAGACTTCAGTTAGAATATGTGGATGTAGTGTTTGCTAACAGACCTGACCCCAACACGCCAATGGAAGGAGATCCATTTAACACTTCAAAATCAAGAACATTCATCATAGAAGAGACGGTTCGAGCAATGACGCATGTGATAAACCAGGGTATGGCTATGTACTGGGGGACATCCCGCTGGAGCTCCATGGAGATTATGgaaGCGTATTCAGTGGCTCGACAGTTCAATCTGATCCCTCCTGTCTGTGAGCAGGCCGAATATCACATGTTTCAGAGAGAGAAGGTGGAAGTACAGCTGCCTGAACTCTTCCATAAGatagGTGTGGGTGCCATGACGTGGTCTCCACTGGCGTGTGGCATCATCTCAGGGAAGTATGACAGTGGTGTGCCTCCTTGTTCCAGAGCCTCCCTCAAGGGCTACCAGTGGATGAAGGACAAGATCCTGAGTGAGGAAGGCCGCCGTCAGCAGGCGAAGCTGAAAGAGTTGCAGGCCATTGCGGAGCGGCTGGGCTGCACACTGCCTCAGCTGGCCATCGctTGGTGTCTGAGGAACGAGGGTGTGAGTTGTGTTTTGCTGGGGGCGTCCAGCACCGATCAGCTCATGGAGAACATTGGAGCAATTCAGgtTCTTCCAAAATTATCGTCCTCGATTATACATGAAGTGGACAGTATCCTAGGCAACAAGCCCTACAGTAAAAAGGACTATCGGTCCTAA

Function

symbol description
kcnab2b Predicted to enable aldo-keto reductase (NADP) activity; potassium channel regulator activity; and transmembrane transporter binding activity. Acts upstream of or within regulation of action potential and regulation of transmission of nerve impulse. Predicted to be located in cytoplasm and plasma membrane. Predicted to be integral component of membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in juxtaparanode region of axon. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Is expressed in Mauthner neurons. Orthologous to human KCNAB2 (potassium voltage-gated channel subfamily A regulatory beta subunit 2).

GO:

id name namespace
GO:0051969 regulation of transmission of nerve impulse biological_process
GO:0098900 regulation of action potential biological_process
GO:0055085 transmembrane transport biological_process
GO:1901379 regulation of potassium ion transmembrane transport biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0006813 potassium ion transport biological_process
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane cellular_component
GO:0044224 juxtaparanode region of axon cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0008076 voltage-gated potassium channel complex cellular_component
GO:0005737 cytoplasm cellular_component
GO:0004033 aldo-keto reductase (NADP) activity molecular_function
GO:0005249 voltage-gated potassium channel activity molecular_function
GO:0044325 ion channel binding molecular_function
GO:0015459 potassium channel regulator activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-080219-36 Predicted to enable aldo-keto reductase (NADP) activity; potassium channel regulator activity; and transmembrane transporter binding activity. Acts upstream of or within regulation of action potential and regulation of transmission of nerve impulse. Predicted to be located in cytoplasm and plasma membrane. Predicted to be integral component of membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in juxtaparanode region of axon. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Is expressed in Mauthner neurons. Orthologous to human KCNAB2 (potassium voltage-gated channel subfamily A regulatory beta subunit 2).

Ensembl:

ensembl_id ENSDARG00000062134

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00042958 False 1787 nonsense_mediated_decay 0.50 15 21067389 21114732
TCONS_00042959 True 1239 mRNA 0.51 15 21067684 21114490

Neighbor

gene id symbol gene type direction distance location
XLOC_021643 pax7b coding upstream 130544 20863145 ~ 20936845 (+)
XLOC_021642 zgc:154075 coding upstream 252905 20803270 ~ 20814484 (+)
XLOC_021641 ttc34 coding upstream 266431 20795781 ~ 20800958 (+)
XLOC_021640 si:ch211-112c15.8 coding upstream 286718 20771899 ~ 20780671 (+)
XLOC_021639 ccdc30 coding upstream 337234 20705849 ~ 20730155 (+)
XLOC_021645 si:dkey-201k7.1 coding downstream 66342 21181074 ~ 21183266 (+)
XLOC_021646 emc1 coding downstream 146581 21261313 ~ 21277522 (+)
XLOC_021647 ubr4 coding downstream 164216 21278948 ~ 21376847 (+)
XLOC_021648 iffo2a coding downstream 265347 21380079 ~ 21417936 (+)
XLOC_021649 tas1r1 coding downstream 310015 21424747 ~ 21440054 (+)
XLOC_021632 CR352228.2 non-coding upstream 595519 20471755 ~ 20471870 (+)
XLOC_021628 NA non-coding upstream 705963 20345310 ~ 20361426 (+)
XLOC_021627 AL953864.1 non-coding upstream 879650 20187625 ~ 20187739 (+)
XLOC_021614 NA non-coding upstream 1591238 19473396 ~ 19476151 (+)
XLOC_021613 CR388168.1 non-coding upstream 1848449 19217528 ~ 19218940 (+)
XLOC_021651 NA non-coding downstream 358370 21473102 ~ 21474482 (+)
XLOC_021656 CR847529.1 non-coding downstream 509003 21623735 ~ 21623849 (+)
XLOC_021659 CR548634.2 non-coding downstream 666845 21781577 ~ 21783450 (+)
XLOC_021660 NA non-coding downstream 791321 21906053 ~ 21914926 (+)
XLOC_021666 NA non-coding downstream 1457426 22572158 ~ 22593289 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location