XLOC_021732 (wnt1)


Basic Information

Item Value
gene id XLOC_021732
gene name wnt1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007134.7
NCBI id CM002907.2
chromosome length 46223584
location 27652906 ~ 27658054 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00043121
TGCGTGAATCTGATTTGAGGTTAATTGGTTAACTTTGCCCTTTCAGATATCATGCGGGTTCTCGCGTTGCTTCTCGCAGTTAAAGCGGCATGTGTCCTCCTGGTGTCCTCTCTCACTGGCACAGGGGCGGTCAACAACAGCGGCCGGTGGTGGGGTATAGTGAATGTGGCATCCTCGGGCAATCTCCTCACTAACTCTAAGAATGTGCAGCTGGTACTCGACCCAAGCCTGGCACTGCTAAGTCGCCGCCAGAGAAAGCTGATCAGGCAAAACCCTGGCATCCTTCATGCTATTGCAGCAGGTCTGCACACAGCCATCAAAGAATGCAAATGGCAGTTTCGTAACCGTCGTTGGAACTGTCCCACTACCCACAGCCCCAATGTCTTTGGCAAAATTGTCAACCGAGGTTGTCGCGAGACTGCGTTTGTGTTTGCCATTACAAGTGCTGGTGTTACTCACGCCGTGGCTCGGTCCTGCTCTGAAGGGGCCATTGAGTCCTGCACCTGTGACTACCGGCGCcgtggtcctggagggccagactGGCACTGGGGAGGCTGCAGCGACAATGTGGAATTTGGCAGGATGTTTGGACGAGAGTTTGTGGATTCCAGCGAGAGGGGCAGAGATCTACGCTATCTGACCAACCTGCACAACAATGAGGCAGGGCGAATGaCTGTCGCATCAGAGATGCAGCAGGAGTGCAAGTGTCACGGGATGTCTGGATCCTGCACTGTGCGAACTTGTTGGATGAGACTTCCCAGCTTCCGTTTAGTGGGAGATTACCTGAAGGACCGTTTTGACGGCGCATCCCGAGTTGTGTATGCCAACAAAGGCAGCAATCGCGCATCCCATCGAGCAGATCCCCGACACCTGGAACCAGAAAACCCAGCGCATAAACTCCCTTCATCTCGGGATCTCGTCTACTTTGAAAAATCACCTAACTTCTGTTCCTACAATGGCAAAACTGGAACACACGGCACATCAGGACGTACCTGCAACAGTTCGTCGCCAGCTCTGGATGGGTGCGAGCTGCTGTGCTGCGGAAGAGGATACAAGACTCGAATGGAGCAGGTCACCGAAAGATGCCACTGTACTTTCCACTGGTGCTGCCATGTGAGCTGCCTCAACTGCACCAGCACACAGACTGTCCATCAGTGTCTATGAGGAGAAAACACAACCGACTCACAAACTGGAGGAGAAGGCTCCCAAATTGGCTATAGAAATGGGCCATTGAGGTGACCCTGGGTTCTCAGCTCTTGCCCTGGAGGAGTTTTGTTTGTCTTTCCTATCTGAAACGCATGCTTCAGTTCATGAAGCTTACAGCTAATGTGTTGATGTTCTGAATCCGGGGTGGTAAATA

Function

symbol description
wnt1 Predicted to enable cytokine activity and frizzled binding activity. Acts upstream of or within brain development. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including central nervous system; midbrain hindbrain boundary neural keel; neural plate; neural rod; and neural tube. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 15 and osteoporosis. Orthologous to human WNT1 (Wnt family member 1).

GO:

id name namespace
GO:0060070 canonical Wnt signaling pathway biological_process
GO:0030154 cell differentiation biological_process
GO:0035284 brain segmentation biological_process
GO:0021587 cerebellum morphogenesis biological_process
GO:0021592 fourth ventricle development biological_process
GO:0030182 neuron differentiation biological_process
GO:0045165 cell fate commitment biological_process
GO:0007275 multicellular organism development biological_process
GO:0007399 nervous system development biological_process
GO:0030902 hindbrain development biological_process
GO:0030917 midbrain-hindbrain boundary development biological_process
GO:0016055 Wnt signaling pathway biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0005102 signaling receptor binding molecular_function
GO:0005109 frizzled binding molecular_function
GO:0005125 cytokine activity molecular_function

KEGG:

id description
ko04310 Wnt signaling pathway
ko04390 Hippo signaling pathway
ko04391 Hippo signaling pathway - fly
ko04150 mTOR signaling pathway
ko04550 Signaling pathways regulating pluripotency of stem cells
ko04916 Melanogenesis
ko05200 Pathways in cancer
ko05205 Proteoglycans in cancer
ko05207 Chemical carcinogenesis - receptor activation
ko05225 Hepatocellular carcinoma
ko05226 Gastric cancer
ko05217 Basal cell carcinoma
ko05224 Breast cancer
ko05165 Human papillomavirus infection
ko05010 Alzheimer disease
ko05022 Pathways of neurodegeneration - multiple diseases
ko04934 Cushing syndrome
ko00536 Glycosaminoglycan binding proteins

ZFIN:

id description
ZDB-GENE-980526-526 Predicted to enable cytokine activity and frizzled binding activity. Acts upstream of or within brain development. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including central nervous system; midbrain hindbrain boundary neural keel; neural plate; neural rod; and neural tube. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 15 and osteoporosis. Orthologous to human WNT1 (Wnt family member 1).

Ensembl:

ensembl_id ENSDARG00000055554

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00043121 True 1360 mRNA 0.53 4 27652906 27658054

Neighbor

gene id symbol gene type direction distance location
XLOC_021731 NA coding upstream 136633 27508867 ~ 27516273 (+)
XLOC_021730 si:dkey-9p24.5 coding upstream 296228 27352072 ~ 27356678 (+)
XLOC_021729 tmprss12 coding upstream 302077 27345826 ~ 27350829 (+)
XLOC_021728 mipa coding upstream 580132 27068225 ~ 27072774 (+)
XLOC_021727 ptges3a coding upstream 592908 27051919 ~ 27059998 (+)
XLOC_021733 rps26 coding downstream 17527 27675581 ~ 27677516 (+)
XLOC_021734 lmbr1l coding downstream 45695 27703749 ~ 27727512 (+)
XLOC_021735 dhh coding downstream 82538 27740592 ~ 27749062 (+)
XLOC_021736 kmt2d coding downstream 98930 27756984 ~ 27768993 (+)
XLOC_021737 kmt2d coding downstream 120616 27778670 ~ 27793877 (+)
XLOC_021724 CT573349.1 non-coding upstream 724048 26928743 ~ 26928858 (+)
XLOC_021722 NA non-coding upstream 1027773 26591124 ~ 26625133 (+)
XLOC_021714 AL845287.1 non-coding upstream 1657765 25995027 ~ 25995141 (+)
XLOC_021691 BX957326.2 non-coding upstream 3092033 24556455 ~ 24560873 (+)
XLOC_021738 NA non-coding downstream 212685 27870739 ~ 27872705 (+)
XLOC_021742 NA non-coding downstream 481705 28139759 ~ 28277430 (+)
XLOC_021745 NA non-coding downstream 732615 28390669 ~ 28420584 (+)
XLOC_021747 dre-let-7g-2 non-coding downstream 878307 28536361 ~ 28536457 (+)
XLOC_021748 dre-let-7h non-coding downstream 878611 28536665 ~ 28536778 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000001_10525795_10530510 WNT1 coding CI01000001 null 10523262 ~ 10530543 (+)