Gene
RNA
| Item | Value |
|---|---|
| gene id | XLOC_022122 |
| gene name | tnnt2a |
| gene type | coding |
| species | zebrafish (Danio rerio) |
| category of species | model fish |
| Item | Value |
|---|---|
| chromosome id | NC_007134.7 |
| NCBI id | CM002907.2 |
| chromosome length | 46223584 |
| location | 5653224 ~ 5685172 (-) |
| genome version | GRCz11_2017_zebrafish_Genome |
| symbol | description |
|---|---|
| tnnt2a | Predicted to enable cytoskeletal protein binding activity and protein-macromolecule adaptor activity. Predicted to be a structural constituent of cytoskeleton. Acts upstream of or within several processes, including animal organ development; circulatory system development; and nitric oxide biosynthetic process. Part of troponin complex. Is expressed in cardiac muscle; cardiovascular system; and mesoderm. Used to study cardiomyopathy and hypertrophic cardiomyopathy. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple). Orthologous to human TNNT2 (troponin T2, cardiac type). |
| id | name | namespace |
|---|---|---|
| GO:0007507 | heart development | biological_process |
| GO:0006936 | muscle contraction | biological_process |
| GO:0006937 | regulation of muscle contraction | biological_process |
| GO:0006941 | striated muscle contraction | biological_process |
| GO:0048793 | pronephros development | biological_process |
| GO:0021591 | ventricular system development | biological_process |
| GO:0055009 | atrial cardiac muscle tissue morphogenesis | biological_process |
| GO:0055010 | ventricular cardiac muscle tissue morphogenesis | biological_process |
| GO:0048845 | venous blood vessel morphogenesis | biological_process |
| GO:0045214 | sarcomere organization | biological_process |
| GO:0010749 | regulation of nitric oxide mediated signal transduction | biological_process |
| GO:0001568 | blood vessel development | biological_process |
| GO:0001569 | branching involved in blood vessel morphogenesis | biological_process |
| GO:0060218 | hematopoietic stem cell differentiation | biological_process |
| GO:0008015 | blood circulation | biological_process |
| GO:0008016 | regulation of heart contraction | biological_process |
| GO:0006809 | nitric oxide biosynthetic process | biological_process |
| GO:0097535 | lymphoid lineage cell migration into thymus | biological_process |
| GO:0001944 | vasculature development | biological_process |
| GO:0060047 | heart contraction | biological_process |
| GO:0060048 | cardiac muscle contraction | biological_process |
| GO:0060840 | artery development | biological_process |
| GO:0005861 | troponin complex | cellular_component |
| GO:0030016 | myofibril | cellular_component |
| GO:0030017 | sarcomere | cellular_component |
| GO:0005737 | cytoplasm | cellular_component |
| GO:0030674 | protein-macromolecule adaptor activity | molecular_function |
| GO:0005523 | tropomyosin binding | molecular_function |
| GO:0030172 | troponin C binding | molecular_function |
| GO:0031013 | troponin I binding | molecular_function |
| GO:0005200 | structural constituent of cytoskeleton | molecular_function |
| GO:0003779 | actin binding | molecular_function |
| GO:0008092 | cytoskeletal protein binding | molecular_function |
| id | description |
|---|---|
| ZDB-GENE-000626-1 | Predicted to enable cytoskeletal protein binding activity and protein-macromolecule adaptor activity. Predicted to be a structural constituent of cytoskeleton. Acts upstream of or within several processes, including animal organ development; circulatory system development; and nitric oxide biosynthetic process. Part of troponin complex. Is expressed in cardiac muscle; cardiovascular system; and mesoderm. Used to study cardiomyopathy and hypertrophic cardiomyopathy. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple). Orthologous to human TNNT2 (troponin T2, cardiac type). |
| ensembl_id | ENSDARG00000020610 |
| RNA id | representative | length | rna type | GC content | exon number | start site | end site |
|---|---|---|---|---|---|---|---|
| TCONS_00043709 | False | 1176 | mRNA | 0.47 | 15 | 5653224 | 5685172 |
| TCONS_00043711 | False | 849 | mRNA | 0.49 | 14 | 5653373 | 5683147 |
| TCONS_00043710 | False | 795 | mRNA | 0.48 | 13 | 5653373 | 5683147 |
| TCONS_00043712 | True | 693 | mRNA | 0.50 | 12 | 5662088 | 5685023 |
| gene id | symbol | gene type | direction | distance | location |
|---|---|---|---|---|---|
| XLOC_022121 | dre-let-7e | coding | downstream | 221707 | 5431418 ~ 5431517 (-) |
| XLOC_022120 | dre-let-7a-5 | coding | downstream | 221905 | 5431196 ~ 5431319 (-) |
| XLOC_022119 | CR936540.1 | coding | downstream | 287879 | 5211021 ~ 5365345 (-) |
| XLOC_022118 | NA | coding | downstream | 453470 | 5190777 ~ 5199754 (-) |
| XLOC_022117 | FO904870.1 | coding | downstream | 527058 | 5119732 ~ 5126166 (-) |
| XLOC_022123 | lad1 | coding | upstream | 2800 | 5687972 ~ 5719453 (-) |
| XLOC_022124 | tnni1a | coding | upstream | 37918 | 5723090 ~ 5729484 (-) |
| XLOC_022125 | phlda3 | coding | upstream | 71270 | 5756442 ~ 5759242 (-) |
| XLOC_022126 | csrp1a | coding | upstream | 80342 | 5765514 ~ 5818992 (-) |
| XLOC_022127 | NA | coding | upstream | 628410 | 6313582 ~ 6324914 (-) |
| XLOC_022128 | NA | non-coding | upstream | 643059 | 6328231 ~ 6354179 (-) |
| XLOC_022129 | BX323087.2 | non-coding | upstream | 714667 | 6399839 ~ 6419850 (-) |
| XLOC_022141 | NA | non-coding | upstream | 1299500 | 6984672 ~ 6997683 (-) |
| XLOC_022144 | NA | non-coding | upstream | 1485694 | 7170866 ~ 7217574 (-) |
