XLOC_022304 (lamb2)


Basic Information

Item Value
gene id XLOC_022304
gene name lamb2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007134.7
NCBI id CM002907.2
chromosome length 46223584
location 20180159 ~ 20258490 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00044040
TCTGACTGAGATAGCGCTCAAACTGTCTGTATGACTAAAAGAACAGGCTGACCATCGACATTATTACTGTAAACATagGCGCGCGGCAGTTGAAGATTCATCACCATACAGCCATGCGCGCGCTTCTGTTGCTGTCCATCTGTGTCCTGTCAGCGGTCAGTGCACAGGAGCCTGATGCTGCTCACGGCTGCACTCATGGAAGCTGCTATCCTGCAACCGGTGACCTCTTGGTGGGTCGAGAAGCCAACCTGAAAGCATCATCCACCTGTGGCCTGCGGAGGAGAGAACCCTACTGCATTGTCAGCCATCTGCAGGAGGAGAAGAAGTGTTTCCAGTGTGATTCACGGCGGCCTTATGATCCTCAGTCCAACCCCGTAAGCCACCGCATCGAGAACGTCATCACCACCTTCAAACCACATCGCAAGAAGTCCTGGTGGCAGTCGGAAAACGGGAAGTCTGATGTTTACCTTCAGCTGGATCTGGAGGCTGAGTTTCACTTCACTCATCTCATCATGACTTTTAAGACTTTCCGTCCAGCAGCCATGTTGATTGAGAGATCTGCAGATTTCGGCCGAAGCTGGCAGGTGTATCGCTACTTTGCTAACGACTGCGAGTCCATCTTTCCAGGAATTTCCCAAGATTCTCTTCGAAAGGTTGATGATGTCATCTGCGAGTCCAGATATTCTGATATCGAGCCGTCGACAGAAGGAGAGGTGATTTTTCGTGTTCTTGACCCTGCTATCAGGATCGAGGACCCTTACAGCCCAAGAATTCAGAACCAGCTGAAGATCACAAATCTTCGCCTGAATCTTACCAAGCTGCACACTCTGGGTGACAATCTGCTGGACTCACGGCCTGAGATCAAGGAGAAATACTACTATGCCATGTATGAGCTGGTCGTCAGGGGCAACTGCTTCTGCTATGGCCACGCCTCTGAGTGTGCGCCAATTGAGGGCATCAGGGATGACATTGAAGGCATGGTTCACGGGAGGTGTGTGTGCAAACACAACACTAAAGGACTGAACTGTGAACAGTGTGACGACTTCTACAATGATCTGCCCTGGAGACCAGCAGAAGGCCGGAACACTAATGCCTGCAAGAAATGCAACTGTAATGGTCACTCCAACCAGTGTCATTTTGACATGGCGGTGTATTTGGCAACGGGGAACATCAGTGGAGGTGTGTGTGACAACTGCCTTCACAACACCATGGGCAGCAACTGTGAGAGCTGTAAACCTTTCTACTACCAGGATCCAACTAGAGATATTAGAGACCCTGGAGTCTGTGTAGCTTGCGATTGTGACCCAGATGGCTCTAAGAACGGTGGTGTTTGTGACGGCCATGATGACCCTTCTCTGGGCATGATTGCTGGACAGTGCCGCTGTAAAGACAATGTTGAAGGTTCACGCTGTGATAAATGCAAGCCTGGTTTCTTTGGCCTGAGTGCTAGTGATCCACGTGGTTGTCAACCATGTAAATGTGACCCCAGGGGTACAGTTTCCGGCAGCTCCCAATGTGACCCTGTGAGCGGAGACTGCTTCTGTAAACGCCTGGTCACTGGACACAGCTGCAACCAATGTCTGCCTGAGCACTGGGCCTTGAGTCATGATACCAGTGGCTGCAGAGGGTGTGACTGTGatgtgggcggagctacagaaaACCAATGCTCAATGGAAACAGGGCAGTGTCAGTGTCGAAGCCACATGATTGGTCGCCAGTGCAACCAGGTGGAGTCTGGGTACTTTTTCATGGCACTTGACCACTACATCTATGAAGCTGAAACTGCCAAACTGGGTCAAggCTCTGTTTTTGAGGAGAGAGAGTACCAGCCGGGTCGCCCCATCTCATGGACAGGCACAGGCTTTGCACGAGCTCCTGAGGGCGGGACGCTGGAATTCGCAATTAACAACATCCCATACTCTATGGAATATGACGTCCTGATTCGCTATGAGCTTCAGATGCCACGTGACTGGGAAGAGGTGCGTGTTGTAGTGATTAGACCTGGTCCTATACCTACCAGCAGTCCATGTGGAAACACCATCCCTGCAGATGATCTGCTAACGGTGTCGCTTTCCTCTGGTGCCAGGTTTGTGGTTCTGCCTCAGCCAGTGTGTTTGGAGAGTGGTGTGAGTTACAAACTGCGCGTGGAGCTCATCCGTTACGCTGACAGGAACAGCATCATTACCTCCACCAATGCCTTTGTGCTTGTTGACTCTATCGCACTTCTCCCCCGTTACTTGTCTCTGGAGATGTTTACTGCAGGAGACCCGGCCTCTGTCGCACGCAAGCAGAGTTTTGAGCGTTACCGCTGCCACGAAACTGCCAAGAGTGTGTCCCGTCCGCAGATGAGTGAAGTGTGTGCCAAACTCATCACCAGCATGTCTGCCCTCATTAATGACGGCGCGCTGGCGTGTGAGTGTGATCCTCAAGGTTCGCTCAGCTCTGAGTGTGATGTCCGTGGCGGTCAGTGCCGCTGCAGGCCCAACATATCTGGCCGGCGCTGTGAGAAATGTGCACCAGGAGCTTACGGCTTTGGCCCATCTGGATGCAAACTTTGTGAATGCAGTTTAGAGGGCTCTCAGAGCCGGTTCTGTGACCTGTACTCAGGACAGTGTCCATGCCGACCTGGAGCATATGGTCAGCGCTGTGATGGTTGTCAGGCAGGACACTGGGGTTTCCCAAACTGCAGGCCATGTCAATGTAACGGCCATGCTGACGAGTGCCATCAGAGGACTGGAGCCTGTCTCAACTGCAGAAGTAATACTGCAGGAGACAAATGTGAAAGGTGTGCTAATGGCTACTATGGTAACCCAGTCCTTGGTTTAGGGAGTCAGTGTCGGCCCTGCCCCTGTCCTGAGGGCCCCAACAGCGGACGCCACTTTGCTGCCTCTTGTTACCAAGACAACCGAAGCCAACAGGTGGTCTGCAACTGCAACCAGGGTTACACAGGTCCACGTTGTGATGAATGTGCTCCTGGCTATTTTGGTGACCCGTCTAAGCCCGGTGGGCAGTGCCAGCCATGTCGTTGCAGTAATAACATCGACCTGTCAGATCCTGAGTCTTGTGACAAGCGCACTGGCCAGTGTCTGAAGTGCCTGTACAACACTGAAGGGCCAGACTGTAGTGTGTGCAGGAGCGGATACTATGGAGACGCTTCTCGACGCAACTGCCGGAAGTGCACCTGTAACTTCCTGGGCACAGAGCGCAGTCAGTGTCTGTCTCGAGATGACTGTGTGTGTCAGCGTGCCACTGGTCAGTGTCAGTGTCTGCCTAATGTTATTGGACAAACCTGTGATCACTGCGCTCCAAACTCCTGGAACCTGGCCAGCGGGCAAGGCTGTGAGCCCTGCGCATGTGACCCTAACAATGCCTACACATCTGCCTGTAATGAGTTTACAGGCCAGTGCCAGTGCCGTGTTGGGTTTGGAGGAAAGACCTGTACAGACTGTCAGGAGAACCACTGGGGTGACCCAAGAGTGCTATGCCGAGCATGTGACTGTGACCCCCGTGGCATCGAGTCATCCCAATGCAACCGTATGACGGGTCACTGCGTGTGCCAGCAGGGTGTTTCTGGTGTCCGCTGTGATCAGTGTGCCCGTGGCTTCTCCGGGACCTTCCCTGACTGTAAGCCTTGCCACCAGTGTTTTGGGGACTGGGACCGTATCGTTCAGGATTTGGCCACCAGAACTAAAGCCCTCACAGATCGAGCCAAGGAGCTTCAGACCACCGGCCTGACTCGAGCATTCGAGAGACGCTTTAAGGAGCTGGAAGACATGCTGGCACAGGCACGGGACATTGTTAATGCCCGTAATGCCACTGCTGAGGCTGTGACCACCCTGATGGGCATGATTGAGGTTCTCAGAGCTCAGATTGGCGAGACCACAGACACACTGAACCAGCAGGAGGGAGACCTGACCGCCGTGCAGGACAGTAACTATGAAGCCAGTAATGCTTTAAgcacactggagagagaagcAAAAGAGCTCAACCTGAACGCAGATCAGCTTAACCGTCAGCTTGACATCCTCAAGAACTCCAACTTCTTGGgTGCATATGACAGCATCCGGGCCTCGTATAATAAGTCACGTGACGCAGAGCACCGATCAAACAGATCTACCACTGACACTCCCAGCACAGTCAGCCAATCAGCAGACACCCGCAAGAAAACAGAGCGGCTGATTGGCCAAAAGAGAGATGATTTTAACCGCAAGAACGCTGCTAACAAGCGTACACTCACTGACTTAAATGCAAAAGTTCAGAATCTGGACTTAAAGAAAATCAACGAAAAGGTGTGTGGAGCTCCAGGTGATGCTCAGTGTGTTGACAGTCCTTGTGGTGGTGCTGGTTGTCGTGATGATGAAGGCAAGCGTCGATGTGGAGGCCTGAACTGTAATGGAGCTGTTGCAGTGGCGGACACTGCTCTGGATAGATCCAAACATGCAGAAAAAGAGCTGGATAAAGCAATGGGGGTAGTGGAGGAGCTTTTTAAGCAGGTGGCGGATGCTAAGACCAAGGCACAGGAAGCGAAAGACAGAGCTCAGGCAGCTCTGGAAAAAGCTAGCGATACCAAGAACAAAGTGGATCATTCTAACAATGATCTAAGGGACCTTATCAAACAAATACGCCAATTCCTCATGCAGGAGGGTGCAGATCCGGACAGCATTGAGGCGGTGGCCAATCGTGTGCTGGAGCTCTCAATCCCTGCCTCTCCCAAGCAGATCCGACACCTAGCAGACGAGATTAAAGACCGTGTCAAGAGTCTGTCTAATGTGGATGCCATTCTGGAGCAAACACAAAATGACGTCCGCAAAGCAGAGCAACTGTTGCTGGATGCCAAGAAAGCTAGGAATAAGGCAGAGGGGGTGAAGAACACAGCTGAGAGTGTGAAAAAGGCCCTGAATGATGCCAGCAGAGCCCAGGCTGCAGCAGAGAAAGCCATCCAGAAAGCTAAGAATGACATTGGCTTAACTCAGAACCAGCTGGCACAGATCCAGTCAGAGACCTCCGCTAGTGAGAGAGATCTTAATGATGCAGTGGACAGACTGGGAGACCTGGAGCGCCAGATCGAGGCATTAAAGACCAAACGTGCCAACAACAGCCTGGATGCTGCACGGGCAGAGGAGACGGCCACCATGGCACGGGACAAAGCCAACGAAGCCAAAGAGATCCTGGATGGTGAGCTGTCCGATAAGTACCGTACTGTTCAGGGTCTGATGGACAATAAGGCGAAAACCATGCAGGACGCCAAGCACAAAGCAGAGCAATTGAGAGATGAAGCCAAGGGGCTGCTGAAAGATGCACAGGATAAACTGCAGAGGCTGGCagAGCTTGAAAAGGACTATGAAGAAAACCAGAAGGTATTGGAAGGCAAAGCCAGGCAGCTGGATGGCCTGGAAGATAAAATGAAGGCGATCCTGAACGCCATCAACAGGCAGATTCAGATCTACAACACCTGTCAATAA

Function

symbol description
lamb2 Predicted to enable integrin binding activity. Predicted to be an extracellular matrix structural constituent. Acts upstream of or within several processes, including basement membrane assembly; glial cell development; and muscle attachment. Predicted to be located in membrane. Predicted to be part of laminin complex. Is expressed in several structures, including adaxial cell; head; musculature system; nervous system; and solid lens vesicle. Human ortholog(s) of this gene implicated in Pierson syndrome and nephrotic syndrome type 5. Orthologous to human LAMB2 (laminin subunit beta 2).

GO:

id name namespace
GO:0021782 glial cell development biological_process
GO:0034446 substrate adhesion-dependent cell spreading biological_process
GO:0016477 cell migration biological_process
GO:0070831 basement membrane assembly biological_process
GO:0009887 animal organ morphogenesis biological_process
GO:0009888 tissue development biological_process
GO:0016203 muscle attachment biological_process
GO:0061053 somite development biological_process
GO:0060041 retina development in camera-type eye biological_process
GO:0043256 laminin complex cellular_component
GO:0005178 integrin binding molecular_function
GO:0005201 extracellular matrix structural constituent molecular_function

KEGG:

id description
ko04151 PI3K-Akt signaling pathway
ko04512 ECM-receptor interaction
ko04510 Focal adhesion
ko05200 Pathways in cancer
ko05222 Small cell lung cancer
ko05165 Human papillomavirus infection
ko05146 Amoebiasis
ko05145 Toxoplasmosis

ZFIN:

id description
ZDB-GENE-081030-4 Predicted to enable integrin binding activity. Predicted to be an extracellular matrix structural constituent. Acts upstream of or within several processes, including basement membrane assembly; glial cell development; and muscle attachment. Predicted to be located in membrane. Predicted to be part of laminin complex. Is expressed in several structures, including adaxial cell; head; musculature system; nervous system; and solid lens vesicle. Human ortholog(s) of this gene implicated in Pierson syndrome and nephrotic syndrome type 5. Orthologous to human LAMB2 (laminin subunit beta 2).

Ensembl:

ensembl_id ENSDARG00000002084

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00044040 True 5462 mRNA 0.52 34 20180159 20258490

Neighbor

gene id symbol gene type direction distance location
XLOC_022303 usp19 coding downstream 2632 20145300 ~ 20177527 (-)
XLOC_022302 si:dkey-32e6.3 coding downstream 36948 20137520 ~ 20143211 (-)
XLOC_022301 lrrc23 coding downstream 46165 20127883 ~ 20133994 (-)
XLOC_022300 tktb coding downstream 53902 20113378 ~ 20126257 (-)
XLOC_022299 si:dkey-32e6.6 coding downstream 79723 20068880 ~ 20100436 (-)
XLOC_022305 lamb2l coding upstream 3080 20261570 ~ 20338597 (-)
XLOC_022306 si:rp71-17i16.6 coding upstream 81710 20340200 ~ 20345473 (-)
XLOC_022307 NA coding upstream 89969 20348459 ~ 20354924 (-)
XLOC_022308 si:rp71-17i16.5 coding upstream 98757 20357247 ~ 20363261 (-)
XLOC_022309 CR749762.1 coding upstream 114824 20373314 ~ 20374396 (-)
XLOC_022295 NA non-coding downstream 234737 19944173 ~ 19945422 (-)
XLOC_022294 CT574579.1 non-coding downstream 272215 19907828 ~ 19907944 (-)
XLOC_022292 NA non-coding downstream 348420 19822434 ~ 19831739 (-)
XLOC_022291 CR352234.4 non-coding downstream 466931 19713095 ~ 19713228 (-)
XLOC_022284 NA non-coding downstream 707540 19467540 ~ 19472619 (-)
XLOC_022310 NA non-coding upstream 160643 20419133 ~ 20421573 (-)
XLOC_022312 NA non-coding upstream 259119 20517609 ~ 20518851 (-)
XLOC_022314 NA non-coding upstream 570855 20829345 ~ 20836604 (-)
XLOC_022315 NA non-coding upstream 599823 20858313 ~ 20938578 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000001_06167374_06195286 LAMB2 coding CI01000001 null 6166681 ~ 6196226 (-)