XLOC_002313 (ucp2)


Basic Information

Item Value
gene id XLOC_002313
gene name ucp2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007121.7
NCBI id CM002894.2
chromosome length 45420867
location 36662640 ~ 36673388 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00004402
ACGTGACTCAAAGGCGTTTAAAAAGAGTCGCTGCGGCGTTCAGAGCACAGCACAGCAGATCACCTGCGGGTTTTAACTATTTCTCTTCCGAGGAGTGTATTTACCCCGACAATAAGCACTTTTATTCTTAGActctttacacatttttaatttaagACTTTTGGAGCATGTTTTTTATTTGCACGAGTTCTCAACGTTTCTCTATGGAAGAACGCGGAAACAAAATTCAAGTTGAAAGTCATTTCAACCAGAGAGATGCTTTTAGAGAATCCTGAAGTTTTCATCTAGGCTAAACCGGTTAGGGTGGAGTTCACCTATCTTGTGTTCACTTCATTGTCTTTCGACACATTCTGCATCACCCTTACGTTCCTGTGATTTCGGCTGCAACTGTAAACATGGTTGGATTCAGAGCTGGTGACGTTCCTCCTACTGCCACCGTGAAGTTTATCGGTGCAGGAACTGCAGCATGCATTGCAGATCTCTTCACCTTTCCACTGGACACCGCAAAAGTTAGACTTCAGATTCAGGGGGAGAACAAAGCCTCCACCAACATGGGCCGTGGTCCGGTGAAATATCGAGGGGTCTTTGGTACGATCAGCACCATGGTGCGAGTGGAGGGGCCACGCAGTCTCTACAGCGGCCTGGTGGCGGGACTGCAGCGTCAGATGAGCTTTGCTTCTGTACGCATCGGCCTCTACGATTCGGTCAAGCAGTTTTACACCAAAGGCTCTGATCATGCTGGGATTGGCAGTCGACTGATGGCTGGTTGTACGACTGGAGCCATGGCCGTGGCTGTGGCTCAACCCACTGATGTAGTGAAGGTCCGGTTTCAGGCTCAGGTCAGCGCTGGGAGCAGTAAACGTTACCATAGTACTATGGACGCATATCGGACCATTGCAAAGGAAGAGGGGTTTCGTGGTTTGTGGAAAGGAACTGGCCCAAACATCACCCGCAATGCCATAGTAAACTGCACTGAGCTAGTGACATACGACCTCATCAAAGATGCACTTCTCAAATCATCTCTGATGACTGATGATCTTCCCTGCCATTTCACATCTGCATTTGGAGCTGGTTTCTGCACTACGATCATTGCTTCCCCTGTCGATGTTGTGAAGACAAGATACATGAACTCTGCCCAGGGCCAGTACAGCAGCGCCCTCAACTGTGCTGTAGCCATGCTGACTAAAGAGGGGCCAAAGGCTTTTTACAAGGGGTTCATGCCATCCTTTCTGAGGCTGGGCTCCTGGAATGTGGTTATGTTCGTCACTTACGAGCAGCTGAAACGGGCCATGATGGCAGCACGCCAAAACTGGCACACTCCTCTTTAAGCAGAGCATGCAGTTCCAGTTGAGCTTCATGCTGACGTGGTTCTGGATTCTCcattttcttcattttgtttacatttttaaacttgattttttttttttccttttttttttttggatttgcaCAATTCTAGAGTCTTTCCAACAATCTGCCAATAAAATGAAATTGGTGTTTTTAAGAATTTCAGACATT
>TCONS_00004403
GCTGCGGCGTTCAGAGCACAGCACAGCAGATCACCTGCGGGTTTTAACTATTTCTCTTCCGAGGAGTGTATTTACCCCGACAATAAGCACTTTTATTCTTAGActctttacacatttttaatttaagACTTTTGGAGCATGTTTTTTATTTGCACGAGTTCTCAACGTTTCTCTATGGAAGAACGCGGAAACAAAATTCAAGTTGAAAGTCATTTCAACCAGAGAGATGCTTTTAGAGAATCCTGAAGTTTTCATCTAGGCTAAACCGAGCTGGTGACGTTCCTCCTACTGCCACCGTGAAGTTTATCGGTGCAGGAACTGCAGCATGCATTGCAGATCTCTTCACCTTTCCACTGGACACCGCAAAAGTTAGACTTCAGATTCAGGGGGAGAACAAAGCCTCCACCAACATGGGCCGTGGTCCGGTGAAATATCGAGGGGTCTTTGGTACGATCAGCACCATGGTGCGAGTGGAGGGGCCACGCAGTCTCTACAGCGGCCTGGTGGCGGGACTGCAGCGTCAGATGAGCTTTGCTTCTGTACGCATCGGCCTCTACGATTCGGTCAAGCAGTTTTACACCAAAGGCTCTGATCATGCTGGGATTGGCAGTCGACTGATGGCTGGTTGTACGACTGGAGCCATGGCCGTGGCTGTGGCTCAACCCACTGATGTAGTGAAGGTCCGGTTTCAGGCTCAGGTCAGCGCTGGGAGCAGTAAACGTTACCATAGTACTATGGACGCATATCGGACCATTGCAAAGGAAGAGGGGTTTCGTGGTTTGTGGAAAG
>TCONS_00004404
GCACAGCAGATCACCTGCGGGTTTTAACTATTTCTCTTCCGAGGAGTGTATTTACCCCGACAATAAGCACTTTTATTCTTAGActctttacacatttttaatttaagACTTTTGGAGCATGTTTTTTATTTGCACGAGTTCTCAACGTTTCTCTATGGAAGAACGCGGAAACAAAATTCAAGTTGAAAGTCATTTCAACCAGAGAGATGCTTTTAGAGAATCCTGAAGTTTTCATCTAGGCTAAACCGGTTAGGGTGGAGTTCACCTATCTTGTGTTCACTTCATTGTCTTTCGACACATTCTGCATCACCCTTACGTTCCTGTGATTTCGGCTGCAACTGTAAACATGGTTGGATTCAGAGCTGGTGACGTTCCTCCTACTGCCACCGTGAAGTTTATCGGTGCAGGAACTGCAGCATGCATTGCAGATCTCTTCACCTTTCCACTGGACACCGCAAAAGTTAGACTTCAGCAACGTAAGCAGGTCCAGGCCTCCATGACTGACCCGGGATAACCTGAAGATGCAGCTTCCCCTCCACTGTGATTCTGTAAAGTTTTTCCATCCACCTTTTGTTCTGTACAGATTCAGGGGGAGAACAAAGCCTCCACCAACATGGGCCGTGGTCCGGTGAAATATCGAGGGGTCTTTGGTACGATCAGCACCATGGTGCGAGTGGAGGGGCCACGCAGTCTCTACAGCGGCCTGGTGGCGGGACTGCAGCGTCAGATGAGCTTTGCTTCTGTACGCATCGGCCTC
>TCONS_00004405
CAGCAGATCACCTGCGGGTTTTAACTATTTCTCTTCCGAGGAGTGTATTTACCCCGACAATAAGCACTTTTATTCTTAGActctttacacatttttaatttaagACTTTTGGAGCATGTTTTTTATTTGCACGAGTTCTCAACGTTTCTCTATGGAAGAACGCGGAAACAAAATTCAAGTTGAAAGTCATTTCAACCAGAGAGATGCTTTTAGAGAATCCTGAAGTTTTCATCTAGGCTAAACCGGTTAGGGTGGAGTTCACCTATCTTGTGTTCACTTCATTGTCTTTCGACACATTCTGCATCACCCTTACGTTCCTGTGATTTCGGCTGCAACTGTAAACATGGTTGGATTCAGAGCTGGTGACGTTCCTCCTACTGCCACCGTGAAGTTTATCGGTGCAGGAACTGCAGCATGCATTGCAGATCTCTTCACCTTTCCACTGGACACCGCAAAAGTTAGACTTCAGGTGAGTCTTCGCTGCATTgagtttaaatgctttttttaaaggcatagttcactcaaaacattAAATTACCTCAACATTAGGCCTAGACAAAATCTGCCCCCACAGAAGATTTCCACAGATTCACTGTACATTTACAATATTGCTGCCTTAAATTATTTAGTTCAATTAAaggaacttttctagtcatctcaacttgcatcagtcaaactgactaaaatattgttaACCTTTGCAAAActtgaaaaatattaagttgaaacctgattaacgtattaaagtaaaagtaacaaaatatttgttgtcttgactt
>TCONS_00004406
aaaacataaaagttgACTAAACTTAATTTTAAGGATATTGCTGCTGAGCTTTTTTTTTGAGTTGACCACTTTCAACCCTCATACTGCACTTGGCTAGATTTAAGTTGAACTCAAAGTTGtcaactttttcttattttttctttacttATTTTTTCATACAGTAAACCAGCATTCCACAATGTCACATAACTTTTATAAACGTTTAAAACCCACATTTGGGAAAAATAAGCGAGGtaactttaatttttgggtgaactcctGCTTTAAATGCCACCTCCTAATTTGAGTGTCAGCTGAGTCATCTGGAGGAATCAAAAAGGCATGACGTGGACCAGAATCAACATGCAGCAGCAAAAAACAGATCATCCTTTTCTTTTCAGGAGGACCGTTTGCAGTTGCACCCATACTGACgtcaacttttatttatttctcttttacaCTAGCAACGTAAGCAGGTCCAGGCCTCCATGACTGACCCGGGATAACCTGAAGATGCAGCTTCCCCTCCACTGTGATTCTGTAAAGTTTTTCCATCCACCTTTTGTTCTGTACAGATTCAGGGGGAGAACAAAGCCTCCACCAACATGGGCCGTGGTCCGGTGAAATATCGAGGGGTCTTTGGTACGATCAGCACCATGGTGCGAGTGGAGGGGCCACGCAGTCTCTACAGCGGCCTGGTGGCGGGACTGCAGCGTCAGATGAGCTTTGCTTCTGTACGCATCGGCCTCTACGATTCGGTCAAGCAGTTTTACACCAAAGGCTCTGATCATGCTGGGATTGGCAGTCGACTGATGGCTGGTTGTACGACTGGAGCCATGGCCGTGGCTGTGGCTCAACCCACTGATGTAGTGAAGGTCCGGTTTCAGGCTCAGGTCAGCGCTGGGAGCAGTAAACGTTACCATAGTACTATGGACGCATATCGGACCATTGCAAAGGAAGAGGGGTTTCGTGGTTTGTGGAAAG

Function

symbol description
ucp2 Predicted to enable oxidative phosphorylation uncoupler activity. Predicted to be involved in adaptive thermogenesis; mitochondrial transmembrane transport; and response to cold. Predicted to act upstream of or within mitochondrial transport. Predicted to be located in mitochondrial inner membrane. Predicted to be integral component of membrane. Is expressed in several structures, including blood; brain; cardiovascular system; pleuroperitoneal region; and ventral mesoderm. Human ortholog(s) of this gene implicated in artery disease (multiple); diabetic neuropathy; end stage renal disease; non-alcoholic fatty liver disease; and obesity. Orthologous to human UCP2 (uncoupling protein 2).

GO:

id name namespace
GO:0009409 response to cold biological_process
GO:1990542 mitochondrial transmembrane transport biological_process
GO:0006839 mitochondrial transport biological_process
GO:1990845 adaptive thermogenesis biological_process
GO:0005743 mitochondrial inner membrane cellular_component
GO:0031966 mitochondrial membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005739 mitochondrion cellular_component
GO:0017077 oxidative phosphorylation uncoupler activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-990708-8 Predicted to enable oxidative phosphorylation uncoupler activity. Predicted to be involved in adaptive thermogenesis; mitochondrial transmembrane transport; and response to cold. Predicted to act upstream of or within mitochondrial transport. Predicted to be located in mitochondrial inner membrane. Predicted to be integral component of membrane. Is expressed in several structures, including blood; brain; cardiovascular system; pleuroperitoneal region; and ventral mesoderm. Human ortholog(s) of this gene implicated in artery disease (multiple); diabetic neuropathy; end stage renal disease; non-alcoholic fatty liver disease; and obesity. Orthologous to human UCP2 (uncoupling protein 2).

Ensembl:

ensembl_id ENSDARG00000043154

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00004402 False 1518 mRNA 0.47 8 36662640 36673388
TCONS_00004403 False 789 processed_transcript 0.49 5 36662669 36669034
TCONS_00004404 False 757 lncRNA 0.47 4 36662689 36668723
TCONS_00004405 False 779 lncRNA 0.38 3 36662692 36666211
TCONS_00004406 True 963 lncRNA 0.45 2 36667996 36669034

Neighbor

gene id symbol gene type direction distance location
XLOC_002312 ucp3 coding upstream 5947 36650222 ~ 36656693 (+)
XLOC_002311 alox5ap coding upstream 198925 36458563 ~ 36463715 (+)
XLOC_002310 uspl1 coding upstream 206655 36439293 ~ 36455985 (+)
XLOC_002309 or104-1 coding upstream 305998 36354863 ~ 36356642 (+)
XLOC_002308 or104-2 coding upstream 311947 36349225 ~ 36350693 (+)
XLOC_002314 rab6a coding downstream 22209 36695597 ~ 36711701 (+)
XLOC_002315 CU694807.1 coding downstream 52850 36726238 ~ 36733011 (+)
XLOC_002316 NA coding downstream 68114 36741502 ~ 36778514 (+)
XLOC_002317 NA coding downstream 131648 36805036 ~ 37064390 (+)
XLOC_002318 BX323076.3 coding downstream 287188 36960576 ~ 36960690 (+)
XLOC_002294 NA non-coding upstream 281597 36201184 ~ 36381043 (+)
XLOC_002299 BX088524.1 non-coding upstream 374137 36287841 ~ 36288503 (+)
XLOC_002289 BX088524.3 non-coding upstream 502353 36158967 ~ 36160287 (+)
XLOC_002283 dre-mir-132-2 non-coding upstream 1017505 35645017 ~ 35645135 (+)
XLOC_002282 BX663516.1 non-coding upstream 1017842 35644719 ~ 35644798 (+)
XLOC_002321 CT027794.1 non-coding downstream 474281 37147669 ~ 37147784 (+)
XLOC_002325 NA non-coding downstream 804857 37478245 ~ 37478556 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01012247_00000024_00000534 UCP2, UCP2B, UCP2A coding CI01012247 null 24 ~ 534 (-)