XLOC_023486 (chrnd)


Basic Information

Item Value
gene id XLOC_023486
gene name chrnd
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007135.7
NCBI id CM002908.2
chromosome length 42172926
location 25683071 ~ 25691020 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00046468
ACAGCTGATAAGGAGTGGTTTGGTTGACTTCTTGGTTTAGATAAGAATGAATGTTGGGAAGAAAATTTGTATGTTTCTTAATTAATTTGTTCACATATTCTGTTCTCCTCAGTTTTGTTGAGCACCCCCTACAGTCCCTGTGGTGCAGCCAGTGGATACTGGAGATTATGTATGTGTGGTTTTTTTCTTCTCTGGATTGATTCCACACCTGTCTATGTCAGTCAAGGGAAAGGCTGGACTGGCACAGCACTAACAGAGATAGGAAGTCATACAACAGCAGGCCATGATGAAAACTGTTCTATTGACGGCGTCCTTGCTTTGCTTCATTTTTCAAGAATGTTGTGGCCGAAATGAAGAGGAGCGCCTCATCAATTATCTTTTTAAGGAGCGTGGCTACAACAAAGAGCTTCGGCCGGTCCAAAATAAAGATGAAACTGTAGATATTTACCTGGCTCTGACACTTTCTAATCTCATTTCCTTGAAAGAGGTTGATGAAACATTGCTTACAAATGTGTGGATGGAGCATggcTGGAAAGATCATAGGCTTACCTGGAATGAATCAGAGTATGACATTCCTGTCCTGCGACTGCCACCAAGTATGGTGTGGTTACCAGAAATTGTTCTGGAAAACAACAATGATGCCCAGTTTCAGGTGGCTTATTACTGTAACGTGCTGATTTATTCCAGTGGAGATATGTACTGGTTGCCTCCAGCTATATTTCGGAGCTCCTGCTCTATAAATGTCAACTACTTCCCCTTTGATTGGCAAAACTGCTCACTAAAGTTCAGctcgTTAACTTACAACGCTAAAGAGATTAGCTTAAATCTGAAAATGGAGCAGGAAAATACAACATACTACAAGGTGGAATGGATCATCATTGATCCTGAAGGATTCACAGAAAATGGTGAGTGGGAAATTGTCCACAAGCCTGCCAGGAGGAACATTTATAAAAGCATCCCGAAAGAAAGCAACAAGCACCAGGATATCACCTTTTACCTGATCATTAAGCGTAAACCGCTGTTCTACATTGTCAACATAATCATTCCCTGTGTGCTCATCTCTTTCTTGGCCTCGCTCGTCTATTACCTGCCTGCTGACAGTGGAGAGAAGATGACGCTGTCAATCTCTGTGCTTCTGGCTCAGTCTGTGTTCCTGCTGCTGATTTCACAGCGTCTGCCTGAGACGTCTATGGCTGTTCCTTTAATTGTCAAgtatctgatgtttaTCATGGTGTTGGTCACTGTGGTGGTGTTGAATTGTGTCATTGTGTTGAACCTGCATTTTCGGACGCCCAGCACACACGTCATGACGGAATGGACCAAAGAGTTCTTTTTGGAGCGTCTTCCTCGTCTCCTGCACATGTCCCTTCCAGTCGAAGACCAACCGGTCCCAGAATCAGCACTGCCCCGGCGCTCCAGCTCATTAGGATACATCGCCCAGGCTGAGGAGTATTACAGTGTTAAATCCCGCAGCGAGCTGATGTTCGAGAAGCAGTCGGAAAGGCATGGTTTGGCCGCTCGTCCCACTCCCAAAGCCACGTACACATCCAGTAATGACTCTGAGGTGTCGGAACAGCTGTACAATGAGATGAAGCCAGCTGTAGAAGGAGCCAATTACATTGTTAAGCACATGCACGACAAAAATGACTATAATGAGGAAAAGGACAACTGGAGCGGGATTGCCAGGACTGTGGACAGGCTCTGCTTCTACGTGGTCACTCCAGTTATGATGATAGGAACCATTTGCATCTTCCTGATGGCCAATTACAATCAGCCACCAGCGTTGCCTTTCCAGGGAGACCCCTTCTCCTATACTGAAGAAAACAGGCGCTATTTGTGACCTTTCATAATAACACAGAAATAGCATAAAGCATATTCTGACAGCAATATAAAGCATGAATATGAATTATCCTTGATTTTCGCTGTTTATGCAGGCTTGATTACTAATATTATGTAGTTATGTATGTTTAATAAGTGTGCTGTGAGAAGAGGCAATAAAGTAATATTGCCTTCCTTTTC

Function

symbol description
chrnd Enables acetylcholine-gated cation-selective channel activity. Acts upstream of or within myofibril assembly. Located in plasma membrane. Is expressed in musculature system and somite. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 3A; congenital myasthenic syndrome 3B; and congenital myasthenic syndrome 3C. Orthologous to human CHRND (cholinergic receptor nicotinic delta subunit).

GO:

id name namespace
GO:0042391 regulation of membrane potential biological_process
GO:0050877 nervous system process biological_process
GO:0034220 ion transmembrane transport biological_process
GO:0007268 chemical synaptic transmission biological_process
GO:0030239 myofibril assembly biological_process
GO:0006811 ion transport biological_process
GO:0007165 signal transduction biological_process
GO:0043005 neuron projection cellular_component
GO:0045202 synapse cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005887 integral component of plasma membrane cellular_component
GO:0045211 postsynaptic membrane cellular_component
GO:0005892 acetylcholine-gated channel complex cellular_component
GO:0030054 cell junction cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0022848 acetylcholine-gated cation-selective channel activity molecular_function
GO:0004888 transmembrane signaling receptor activity molecular_function
GO:0005216 ion channel activity molecular_function
GO:0005230 extracellular ligand-gated ion channel activity molecular_function
GO:0030594 neurotransmitter receptor activity molecular_function

KEGG:

id description
ko04080 Neuroactive ligand-receptor interaction
ko04040 Ion channels

ZFIN:

id description
ZDB-GENE-030131-6665 Enables acetylcholine-gated cation-selective channel activity. Acts upstream of or within myofibril assembly. Located in plasma membrane. Is expressed in musculature system and somite. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 3A; congenital myasthenic syndrome 3B; and congenital myasthenic syndrome 3C. Orthologous to human CHRND (cholinergic receptor nicotinic delta subunit).

Ensembl:

ensembl_id ENSDARG00000019342

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00046468 True 2019 mRNA 0.44 12 25683071 25691020

Neighbor

gene id symbol gene type direction distance location
XLOC_023485 cnksr2a coding downstream 9629 25485264 ~ 25673442 (-)
XLOC_023484 mbtps2 coding downstream 221804 25447911 ~ 25461267 (-)
XLOC_023483 phex coding downstream 240725 25404358 ~ 25442346 (-)
XLOC_023482 ptchd1 coding downstream 318296 25347503 ~ 25364775 (-)
XLOC_023481 adgrg2a coding downstream 381360 25285758 ~ 25301711 (-)
XLOC_023487 NA coding upstream 59616 25750636 ~ 25754146 (-)
XLOC_023488 klhl24b coding upstream 69966 25760986 ~ 25788841 (-)
XLOC_023489 CR352209.2 coding upstream 314609 26005629 ~ 26025582 (-)
XLOC_023490 NA coding upstream 340228 26031248 ~ 26032271 (-)
XLOC_023491 NA coding upstream 541680 26232700 ~ 26236578 (-)
XLOC_023665 dre-mir-735 misc upstream 12486941 38177961 ~ 38178027 (-)
XLOC_023471 NA non-coding downstream 853670 24800776 ~ 24829401 (-)
XLOC_023468 NA non-coding downstream 987314 24553793 ~ 24695757 (-)
XLOC_023466 NA non-coding downstream 1180049 24416324 ~ 24503022 (-)
XLOC_023467 NA non-coding downstream 1190554 24492203 ~ 24492517 (-)
XLOC_023461 NA non-coding downstream 1584192 24095316 ~ 24098879 (-)
XLOC_023496 NA non-coding upstream 663676 26354696 ~ 26369185 (-)
XLOC_023503 NA non-coding upstream 950879 26641899 ~ 26648023 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000018_06881855_06890718 CHRND coding CI01000018 null 6881599 ~ 6890718 (-)