XLOC_025673 (polr3k)


Basic Information

Item Value
gene id XLOC_025673
gene name polr3k
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 46380086 ~ 46384147 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00050537
TATGGCGAGCCAATAATACAGAGGCACATTGATTGTCATGTGCTTCCTGTAGCGACTTAGAAAGGACTGTGTGTAAATACCAACTTCAGTTGCATCAGAAAGAAACTATAACTGTATTTACTACGTAACATAATCTATGACTGTTTGAAAATGCTCCTGTTTTGTCCGACATGTGGGAATGTGTTAATCGTGGAAGAAGGACAGCGATGCTTTAGATTCGCGTGTAACACATGTCCATATGTGCACAACATCACGAGGAAGGTAAACAACAGAAAGTACCCCAAACTGAAGGAGGTTGATGATGTTCTTGGAGGATCTGCTGCTTGGGAAAATGTGGATTCCACTGCAGAACCCTGTCCAAAATGTGAGCACCCAAGGGCTTATTTCATGCAGATTCAAACCAGGTCTGCCGATGAACCAATGACAACCTTCTACAAATGCTGCAATATACAGTGTGGCCATCGATGGAGAGACTAAATCTAGactttgtttgggaaatattagaatAATGTATTGAATTGTTGGAACCCCATCATCATTTGTGTAAATTAAAACCCTCAGATGCTCTTTAAACGTTATTTCCCTCATCTAGAAGCTTTGTAAAATTAGGTTGTGTGCAATAACCAGATCATTCACTTGCCTTTTTTGGTGTTTATGTGTGAAAGTAATAAAACAGATGCTCATATTTGA

Function

symbol description
polr3k Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to contribute to DNA-directed 5'-3' RNA polymerase activity. Acts upstream of or within hematopoietic stem cell homeostasis. Predicted to be located in nucleolus. Predicted to be part of RNA polymerase III complex. Is expressed in hematopoietic system. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy. Orthologous to human POLR3K (RNA polymerase III subunit K).

GO:

id name namespace
GO:0006351 transcription, DNA-templated biological_process
GO:0006386 termination of RNA polymerase III transcription biological_process
GO:0042779 tRNA 3'-trailer cleavage biological_process
GO:0061484 hematopoietic stem cell homeostasis biological_process
GO:0005634 nucleus cellular_component
GO:0005666 RNA polymerase III complex cellular_component
GO:0005730 nucleolus cellular_component
GO:0003899 DNA-directed 5'-3' RNA polymerase activity molecular_function
GO:0046872 metal ion binding molecular_function
GO:0003676 nucleic acid binding molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG:

id description
ko03020 RNA polymerase
ko04623 Cytosolic DNA-sensing pathway
ko03021 Transcription machinery

ZFIN:

id description
ZDB-GENE-040718-291 Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to contribute to DNA-directed 5'-3' RNA polymerase activity. Acts upstream of or within hematopoietic stem cell homeostasis. Predicted to be located in nucleolus. Predicted to be part of RNA polymerase III complex. Is expressed in hematopoietic system. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy. Orthologous to human POLR3K (RNA polymerase III subunit K).

Ensembl:

ensembl_id ENSDARG00000037835

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00050537 True 690 mRNA 0.39 3 46380086 46384147

Neighbor

gene id symbol gene type direction distance location
XLOC_025672 mrtfbb coding upstream 14630 46271911 ~ 46365456 (+)
XLOC_025671 unkl coding upstream 561725 45778810 ~ 45818361 (+)
XLOC_025670 gper1 coding upstream 609997 45756605 ~ 45770089 (+)
XLOC_025669 gpr146 coding upstream 662511 45687266 ~ 45717575 (+)
XLOC_025668 dre-mir-2195 coding upstream 744900 45635077 ~ 45635186 (+)
XLOC_025674 sc:d0202 coding downstream 41115 46425262 ~ 46427696 (+)
XLOC_025675 si:ch211-66e2.3 coding downstream 60478 46444625 ~ 46454343 (+)
XLOC_025676 si:ch211-66e2.5 coding downstream 73303 46457450 ~ 46473737 (+)
XLOC_025677 tyk2 coding downstream 95558 46479705 ~ 46555542 (+)
XLOC_025678 NA coding downstream 160867 46545014 ~ 46545481 (+)
XLOC_025429 BX649540.1 misc upstream 16131050 30248739 ~ 30249036 (+)
XLOC_025667 CR392042.1 non-coding upstream 773629 45602345 ~ 45606457 (+)
XLOC_025664 NA non-coding upstream 1126554 45246037 ~ 45253532 (+)
XLOC_025662 CR385066.1 non-coding upstream 1491933 44888037 ~ 44888153 (+)
XLOC_025660 NA non-coding upstream 2326316 44000293 ~ 44053770 (+)
XLOC_025683 NA non-coding downstream 414365 46798512 ~ 46803047 (+)
XLOC_025684 NA non-coding downstream 450710 46834857 ~ 46838638 (+)
XLOC_025685 NA non-coding downstream 723623 47107770 ~ 47109473 (+)
XLOC_025689 NA non-coding downstream 1011388 47395535 ~ 47409399 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000046_00777923_00780186 RPC11, POLR3K, POLR3K.S misc CI01000046 null 774434 ~ 780293 (-)
striped catfish (Pangasianodon hypophthalmus) polr3k polr3k,LOC107703329 misc NC_047617.1 CM018563.1 18084118 ~ 18087745 (+)