XLOC_034725 (otub1b)


Basic Information

Item Value
gene id XLOC_034725
gene name otub1b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007118.7
NCBI id CM002891.2
chromosome length 74282399
location 24815809 ~ 24828887 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00067577
CGGAAGAGTACACGGGAGAGGGGGCGGTGGAAAAAGAACTCAATCAAGATGGCGGATGAGCAGCAGGAATCATCACAGGGAGAGATGGAGGGAGTCAACTGCCTCGCATATGATGAAGCCATTATGGCACAGCAGGACCGCATTCAGCAAGAGATAGCCACCAGTAACCCTTTAGTGTCGGACAGACAAGAGCTCTCTGTGCTTAAGGGAGAATATGCCATGGAGGACACCATATACCAACTCAAGATACAGGACCTTCACAAAAAGTATTCGAGCATTCGGAAAACACGGCCAGATGGAAATTGTTTCTACAGAGCTTTTGGCTTTGCACATTTGGAGTCACTATTGGAAGACAGCAAAGAGCTGCAAAGgtTCAAAGCTGTTGCAGCAAAGAGCAAGCTGGACCTTGTAAACCAGGGCTTCACTGAGTTCACAATTGAGGACTTTCACAACACCTTCATGGACTTGATTGAGCTATGTGAAAAGCAGCAGTCGCTCGGAGAAGTGCTGAGCTCCTTCAATGACCAGAGTGTGTCCGACTACATAGTGGTTTATCTGAGGCTTCTCACCTCTGGATACCTGCAGAGGGAGCATGTGTTCTTTCAGCACTTCATAGAGGGCGGACGCTCCGTCAAAGAGTTCTGCCAGCAGGAGGTGGAACCCATGTCAAAAGAAAGTGACCACATTCATATCATTGCCTTAGCACAGGCACTGAACGTGCCCGTATTAGTGGAATACATGGACAGAGGAGAGGGTGGAACGGTGAACAATCATGTCTTTCCTGAAGGAAGTGAGCCACGCATCTTCCTGCTCTACCGCCCAGGCCACTACGACATCCTGTATAAGTGATACTCCTACATATATATTCTCTGTGGTTCCATTGTGAAGAAACCATCTCAGTTCTACAGCCAAGTTGTCATATGTATGCGTACATACATGTTTGCCAGGCTATtattaaaaatcacaataaaaagaTTCAATCCAGTTTTTTCTTCCATTACAAAGTGAATTTGTcttcattacagacaatttaagcTATTGATCTCAGAACAATTGACACTGCATCAAACGGCAGCATTACGGTTGTACAGTAGTTTATTTTTTGGTTATGTGGTTGTAAATGTAAACTTGCTTTTAGTGTTTTTCCTTTGTTACACTGCCTTTCATGAGTTTTATTAAAGGGATTTACACCTCTA
>TCONS_00067578
TTATTGGGTCAGGTCTAGGTCTTGTGTGGCAGGTGTGTGTCTAAAACATTTATGACTTCATCATTACTGATGAATATGTTTTGCAGGAGTCAACTGCCTCGCATATGATGAAGCCATTATGGCACAGCAGGACCGCATTCAGCAAGAGATAGCCACCAGTAACCCTTTAGTGTCGGACAGACAAGAGCTCTCTGTGCTTAAGGGAGAATATGCCATGGAGGACACCATATACCAACTCAAGATACAGGACCTTCACAAAAAGTATTCGAGCATTCGGAAAACACGGCCAGATGGAAATTGTTTCTACAGAGCTTTTGGCTTTGCACATTTGGAGTCACTATTGGAAGACAGCAAAGAGCTGCAAAGgtTCAAAGCTGTTGCAGCAAAGAGCAAGCTGGACCTTGTAAACCAGGGCTTCACTGAGTTCACAATTGAGGACTTTCACAACACCTTCATGGACTTGATTGAGCTATGTGAAAAGCAGCAGTCGCTCGGAGAAGTGCTGAGCTCCTTCAATGACCAGAGTGTGTCCGACTACATAGTGGTTTATCTGAGGCTTCTCACCTCTGGATACCTGCAGAGGGAGCATGTGTTCTTTCAGCACTTCATAGAGGGCGGACGCTCCGTCAAAGAGTTCTGCCAGCAGGAGGTGGAACCCATGTCAAAAGAAAGTGACCACATTCATATCATTGCCTTAGCACAGGCACTGAACGTGCCCGTATTAGTGGAATACATGGACAGAGG

Function

symbol description
otub1b Predicted to enable thiol-dependent deubiquitinase and ubiquitin binding activity. Predicted to be involved in negative regulation of double-strand break repair; negative regulation of histone H2A K63-linked ubiquitination; and protein K48-linked deubiquitination. Predicted to act upstream of or within protein deubiquitination. Predicted to be active in nucleus. Orthologous to human OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1).

GO:

id name namespace
GO:1901315 negative regulation of histone H2A K63-linked ubiquitination biological_process
GO:0071108 protein K48-linked deubiquitination biological_process
GO:2000780 negative regulation of double-strand break repair biological_process
GO:0016579 protein deubiquitination biological_process
GO:0006508 proteolysis biological_process
GO:0005634 nucleus cellular_component
GO:0019784 NEDD8-specific protease activity molecular_function
GO:0004843 thiol-dependent ubiquitin-specific protease activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0008233 peptidase activity molecular_function
GO:0008234 cysteine-type peptidase activity molecular_function
GO:0043130 ubiquitin binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040718-204 Predicted to enable thiol-dependent deubiquitinase and ubiquitin binding activity. Predicted to be involved in negative regulation of double-strand break repair; negative regulation of histone H2A K63-linked ubiquitination; and protein K48-linked deubiquitination. Predicted to act upstream of or within protein deubiquitination. Predicted to be active in nucleus. Orthologous to human OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1).

Ensembl:

ensembl_id ENSDARG00000011462

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00067577 False 1196 mRNA 0.44 7 24815809 24828887
TCONS_00067578 True 744 mRNA 0.47 6 24816256 24828296

Neighbor

gene id symbol gene type direction distance location
XLOC_034724 cmtr2 coding downstream 96154 24714840 ~ 24719655 (-)
XLOC_034723 calb2b coding downstream 115824 24681278 ~ 24699985 (-)
XLOC_034722 rgp1 coding downstream 170269 24627076 ~ 24645540 (-)
XLOC_034721 pik3c3 coding downstream 194113 24593209 ~ 24621696 (-)
XLOC_034720 NA coding downstream 225944 24580967 ~ 24589865 (-)
XLOC_034726 fam113 coding upstream 1689 24830576 ~ 24838857 (-)
XLOC_034727 BX511061.1 coding upstream 11814 24840701 ~ 24853898 (-)
XLOC_034728 adad2 coding upstream 33584 24862471 ~ 24875421 (-)
XLOC_034729 rcor2 coding upstream 150946 24979833 ~ 24995640 (-)
XLOC_034730 arl2 coding upstream 218332 25047219 ~ 25049377 (-)
XLOC_034707 CR388231.6 non-coding downstream 745913 24058768 ~ 24069896 (-)
XLOC_034702 NA non-coding downstream 866124 23946001 ~ 23949685 (-)
XLOC_034701 CR388231.5 non-coding downstream 909316 23902484 ~ 23906493 (-)
XLOC_034698 NA non-coding downstream 957482 23852487 ~ 23858327 (-)
XLOC_034734 CU464085.1 non-coding upstream 462146 25291033 ~ 25291152 (-)
XLOC_034735 CU929416.1 non-coding upstream 510869 25339756 ~ 25523467 (-)
XLOC_034737 CU467013.2 non-coding upstream 934297 25763184 ~ 25763298 (-)
XLOC_034738 CU467013.1 non-coding upstream 962342 25791229 ~ 25791355 (-)

Expression


Co-expression Network