XLOC_035484 (atp2a2a)


Basic Information

Item Value
gene id XLOC_035484
gene name atp2a2a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007119.7
NCBI id CM002892.2
chromosome length 54304671
location 11687254 ~ 11744994 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00069611
ACCAGTGAACGGACGAGAAGGACGGCGAAAGGGGTCGAGCGTCACATTTCCAGGCAGGCAGAGGCTTGGACGGGGCTGATTGTGATGTACTAAGCAAGGAGCTTTTCTTTGGCGTTCACTGACACACATTTCTTTGGGGCACAAGAAGAAGACTGTTTGGATAAGACTCCTGGAAGATTTCTTGACTTGAGCGGGATTCTCTTCCCATCTAACCATGGAGAACGCTCACACCAAGAGTGTGGAAGAAGTTTATAGTAATTTCAGCGTCAACGAGAGCACGGGACTGACTTTAGACCAGGTGAAAAGGAATAGAGACAAATGGGGTCCTAACGAGTTGCCTGCAGAGGAAgGAAAGTCAATATGGGAGCTTGTCATTGAGCAGTTTGAAGATTTACTTGTGCGGATTCTTCTACTGGCAGCTTGCATATCTTTTGTATTAGCCTGGTTCGAGGAGGGGGAGGAAACTATCACTGCCTTTGTGGAGCCTTTTGTAATCTTACTGATTCTTATAGCTAATGCCATCGTCGGCGTTTGGCAGGAACGTAATGCAGAAAATGCCATTGAAGCCCTCAAAGAGTACGAGCCAGAGATGGGCAAGGTGTACCGTCAGGACAGGAAGTCCGTGCAAAGGATCAAAGCCAAAGACATCGTGCCTGGAGACATAGTGGAGGTCGCTGtgGGTGATAAGGTGCCTGCCGATATCCGTATCAGTGCCATCAAGTCCACCACACTCCGAGTGGACCAGTCTATTCTGACAggcgaGTCTGTATCTGTCATCAAGCATACTGACCCCGTGCCGGATCCCCGTGCCGTCAATCAGGACAAGAAGAACATGTTGTTCTCAGGAACCAACATTGCTGCAGGTAAAGCCATCGGCGTAGTGGTGGCCACAGGTGTGAACACAGAGATCGGTAAGATCCGTGATGAAATGGCCTCCACCGAGCAGGAGAGGACGCCGCTGCAGCAGAAGCTGGACGAGTTTGGCGAGCAGCTCTCTAAAGTCATCTCCCTGATCTGCATCGCCGTCTGGATCATCAACATCGGCCACTTCAACGACCCCGTCCACGGTGGCTCCTGGATCCGTGGCGCCGTTTACTACTTCAAGATCGCCGTGGCTCTGGCTGTAGCTGCCATTCCTGAAGGTCTGCCCGCTGTCATCACCACCTGCCTGGCTCTCGGCACTCGCCGTATGGCCAAGAAGAACGCCATCGTCCGCTCTCTGCCCTCTGTGGAGACTCTGGGCTGCACCTCAGTCATCTGCTCCGACAAGACTGGCACCCTCACCACCAACCAGATGTCCGTCTGcaggATGTTCATCATAGACAAGGCTGAAGGAGAAAACTGCTCACTGACTGAATTCACCATCTCTGGCTCCACATATGCTCCTGAAGGAGACGTATGCCTTGACAACAGAATCGTGAAGTGCTCCCAATATGATGGTTTGGTGGAGTTGGCGACCATCTGTGCCTTGTGCAATGACTCCTCCCTGGATTTTAATGAGTCCAAAGGTGTTTATGAGAAGGTTGGAGAGGCGACAGAAACGGCTCTAACCTGCCTGGTGGAAAAGATGAACGTCTTTGACACTGACGTCAGGAACCTGTCAAAGATCGAGCGAGCCAATGCCTGCAATGCTgTGATCAAGCAGCTGATGAAGAAGGAGTTCACCCTCGAGTTCTCCAGAGACAGAAAGTCCATGTCTGTGTACTGCTCCCCAAACAAAGCCAAATCCTCCTCTTCTAAGATGTTTGTCAAGGGAGCTCCAGAAGGGGTGATCGATAGGTGTGCATATGTCCGTGTTGGAGGATCCAAGGTTCCTCTGACTCAGGGCATCAAGGACAAGATCATGTCTGTGATCCGCGAGTACGGGACTGGCCGGGATACCCTGCGCTGCCTGGCACTGGCCACCCGTGACAATCCGCTCAAGAAAGAGGAGATGGTCCTGTCAGATACCGCCCGGTTTGCTGATTATgagTCTGATCTAACCTTCGTGGGCTGTGTGGGCATGCTGGACCCTCCTCGAACAGAAGTAGCGGCCTCCATCAAGCTCTGCCGCCATGCTGGGATCAGGGTCATCATGATCACCGGTGATAACAAAGGCACGGCCGTGGCCATCTGCAGACGCATCGGCATCTTCTCTGACGAGGACGACGTCCACCGCATGGCTTTCACGGGACGCGAGTTTGACGACCTGTCGCCCCATGCCCAGCGTGAGGCGGTCACTGTGGCCCGCTGCTTCGCACGAGTCGAGCCTTCACACAAGTCCAAGATTGTGGAGTTCCTGCAGGGCTTTGATGAGATCACTGCCATGACAGGAGATGGTGTGAATGATGCCCCTGCCCTGAAAAAGGCAGAGATTGGCATCGCCATGGGCTCTGGCACTGCTGTGGCCAAGACAGCCTCGGAGATGGTCCTCGCTGATGACAACTTTTCCACCATTGTGGCCGCCGTTGAAGAAGGCAGAGCAATCTACAACAACATGAAGCAGTTCATCCGCTACCTGATCTCCTCCAACGTGGGAGAGGTCGTCTGTATCTTCCTGACCGCTGCATTGGGTTTCCCTGAGGCGCTGATCCCCGTCCAGCTGCTGTGGGTGAACCTGGTGACTGACGGCTTGCCTGCCACCGCTCTAGGCTTCAACCCCCCTGATCTGGACATCATGAACAAGCCCCCCCGAAGCGCCAAAGAGCCCCTCATCTCCGGATGGCTCTTTTTCAGATACTTGGCCATCGGCTGTTATGTGGGTGCTGCTACTGTAGGAGCTGCAGCCTGGTGGTTCATTGTTGCTGATGATGGTCCAATGATCACACTTTACCAGCTGAGTCATTTCCTGCAGTGTTCTCCCGATAATCCTGACTTCCAGGACTTGGAGTGTCACGTCTTCGAGTCTCCTTACCCCATGACCATGGCCCTGTCTGTGCTCGTCACCATTGAGATGTGCAACGCCCTCAACAGTCTATCCGAGAACCAGTCTCTGGTGCGCATGCCACCCTGGGAGAATATCTGGCTGCTGGGAGCCATCTGTCTCTCCATGTCTCTGCACTTCCTCATCCTCTATGTGGAGCCACTGCcgGTCATCTTCCAGATCACTCCTCTGAATGTGACGCAGTGGATGATGGTGCTGAAGATCTCGCTGCCTGTCATTCTCTTGGACGAGCTGCTCAAATTTGTGGCGAGGACCTACCTGGAGCCTGctCCAGAGGATTAAGCCCATCTACTCTCTGTATTCCATGCAGAAGCTTTTCTTGACTTTAGTGCATGTATGTTGTTTCAAGCAGCTCCACACATCAGTCTAGGCCTGCATGTCCAAACAAAAAAAACCTGAATAATTTGCATCGTTAGTTTAGAAGAAGCTCAAACATTAGGAGCGACAAATAAAGCTGAACATTGAAATTTGGAAATACTCTTGAAATGTGACATTAAAGCAGATTTGATGATGCATGTCCCCCCTAATGTTAAACTTTTGTATAGGAactatttaatttgaaaaaaatattgaaccttttgtgaaatatgtaaattaaccaaaaaaaaacCTGATAGTTTATGTTGCTGTTTTGCGCAGGGATGTGCAATATGTTTTAAAGCCGAGGCTCAtttcaggtgtgtgtttgtgtgtgtgagagacattGAGAAACAGGCCGTCTTTTACAGCCGGagctgccagatcagtgttgtaaTTATCACAATCAATTGTGGTTCATTAATAAAAAGATATTACATGGTC
>TCONS_00069612
AGTGAACGGACGAGAAGGACGGCGAAAGGGGTCGAGCGTCACATTTCCAGGCAGGCAGAGGCTTGGACGGGGCTGATTGTGATGTACTAAGCAAGGAGCTTTTCTTTGGCGTTCACTGACACACATTTCTTTGGGGCACAAGAAGAAGACTGTTTGGATAAGACTCCTGGAAGGTGCATTTGCCCGTCTCAACTTTCCACATATGTTCTTCATTGTGGATGTCAATGCATGTGTCACTCATAGGCATATTCTTATATTTttgttcttcctttttttttgtaaacaaggCAGATTTCTTGACTTGAGCGGGATTCTCTTCCCATCTAACCATGGAGAACGCTCACACCAAGAGTGTGGAAGAAGTTTATAGTAATTTCAGCGTCAACGAGAGCACGGGACTGACTTTAGACCAGGTGAAAAGGAATAGAGACAAATGGGGTCCTAACGAGTTGCCTGCAGAGGAAgGAAAGTCAATATGGGAGCTTGTCATTGAGCAGTTTGAAGATTTACTTGTGCGGATTCTTCTACTGGCAGCTTGCATATCTTTTGTATTAGCCTGGTTCGAGGAGGGGGAGGAAACTATCACTGCCTTTGTGGAGCCTTTTGTAATCTTACTGATTCTTATAGCTAATGCCATCGTCGGCGTTTGGCAGGAACGTAATGCAGAAAATGCCATTGAAGCCCTCAAAGAGTACGAGCCAGAGATGGGCAAGGTGTACCGTCAGGACAGGAAGTCCGTGCAAAGGATCAAAGCCAAAGACATCGTGCCTGGAGACATAGTGGAGGTCGCTGtgGGTG
>TCONS_00069613
ATGGAGAACGCTCACACCAAGAGTGTGGAAGAAGTTTATAGTAATTTCAGCGTCAACGAGAGCACGGGACTGACTTTAGACCAGGTGAAAAGGAATAGAGACAAATGGGGTCCTAACGAGTTGCCTGCAGAGGAAgGAAAGTCAATATGGGAGCTTGTCATTGAGCAGTTTGAAGATTTACTTGTGCGGATTCTTCTACTGGCAGCTTGCATATCTTTTGTATTAGCCTGGTTCGAGGAGGGGGAGGAAACTATCACTGCCTTTGTGGAGCCTTTTGTAATCTTACTGATTCTTATAGCTAATGCCATCGTCGGCGTTTGGCAGGAACGTAATGCAGAAAATGCCATTGAAGCCCTCAAAGAGTACGAGCCAGAGATGGGCAAGGTGTACCGTCAGGACAGGAAGTCCGTGCAAAGGATCAAAGCCAAAGACATCGTGCCTGGAGACATAGTGGAGGTCGCTGtgGGTGATAAGGTGCCTGCCGATATCCGTATCAGTGCCATCAAGTCCACCACACTCCGAGTGGACCAGTCTATTCTGACAggcgaGTCTGTATCTGTCATCAAGCATACTGACCCCGTGCCGGATCCCCGTGCCGTCAATCAGGACAAGAAGAACATGTTGTTCTCAGGAACCAACATTGCTGCAGGTAAAGCCATCGGCGTAGTGGTGGCCACAGGTGTGAACACAGAGATCGGTAAGATCCGTGATGAAATGGCCTCCACCGAGCAGGAGAGGACGCCGCTGCAGCAGAAGCTGGACGAGTTTGGCGAGCAGCTCTCTAAAGTCATCTCCCTGATCTGCATCGCCGTCTGGATCATCAACATCGGCCACTTCAACGACCCCGTCCACGGTGGCTCCTGGATCCGTGGCGCCGTTTACTACTTCAAGATCGCCGTGGCTCTGGCTGTAGCTGCCATTCCTGAAGGTCTGCCCGCTGTCATCACCACCTGCCTGGCTCTCGGCACTCGCCGTATGGCCAAGAAGAACGCCATCGTCCGCTCTCTGCCCTCTGTGGAGACTCTGGGCTGCACCTCAGTCATCTGCTCCGACAAGACTGGCACCCTCACCACCAACCAGATGTCCGTCTGcaggATGTTCATCATAGACAAGGCTGAAGGAGAAAACTGCTCACTGACTGAATTCACCATCTCTGGCTCCACATATGCTCCTGAAGGAGACGTATGCCTTGACAACAGAATCGTGAAGTGCTCCCAATATGATGGTTTGGTGGAGTTGGCGACCATCTGTGCCTTGTGCAATGACTCCTCCCTGGATTTTAATGAGTCCAAAGGTGTTTATGAGAAGGTTGGAGAGGCGACAGAAACGGCTCTAACCTGCCTGGTGGAAAAGATGAACGTCTTTGACACTGACGTCAGGAACCTGTCAAAGATCGAGCGAGCCAATGCCTGCAATGCTgTGATCAAGCAGCTGATGAAGAAGGAGTTCACCCTCGAGTTCTCCAGAGACAGAAAGTCCATGTCTGTGTACTGCTCCCCAAACAAAGCCAAATCCTCCTCTTCTAAGATGTTTGTCAAGGGAGCTCCAGAAGGGGTGATCGATAGGTGTGCATATGTCCGTGTTGGAGGATCCAAGGTTCCTCTGACTCAGGGCATCAAGGACAAGATCATGTCTGTGATCCGCGAGTACGGGACTGGCCGGGATACCCTGCGCTGCCTGGCACTGGCCACCCGTGACAATCCGCTCAAGAAAGAGGAGATGGTCCTGTCAGATACCGCCCGGTTTGCTGATTATgagTCTGATCTAACCTTCGTGGGCTGTGTGGGCATGCTGGACCCTCCTCGAACAGAAGTAGCGGCCTCCATCAAGCTCTGCCGCCATGCTGGGATCAGGGTCATCATGATCACCGGTGATAACAAAGGCACGGCCGTGGCCATCTGCAGACGCATCGGCATCTTCTCTGACGAGGACGACGTCCACCGCATGGCTTTCACGGGACGCGAGTTTGACGACCTGTCGCCCCATGCCCAGCGTGAGGCGGTCACTGTGGCCCGCTGCTTCGCACGAGTCGAGCCTTCACACAAGTCCAAGATTGTGGAGTTCCTGCAGGGCTTTGATGAGATCACTGCCATGACAGGAGATGGTGTGAATGATGCCCCTGCCCTGAAAAAGGCAGAGATTGGCATCGCCATGGGCTCTGGCACTGCTGTGGCCAAGACAGCCTCGGAGATGGTCCTCGCTGATGACAACTTTTCCACCATTGTGGCCGCCGTTGAAGAAGGCAGAGCAATCTACAACAACATGAAGCAGTTCATCCGCTACCTGATCTCCTCCAACGTGGGAGAGGTCGTCTGTATCTTCCTGACCGCTGCATTGGGTTTCCCTGAGGCGCTGATCCCCGTCCAGCTGCTGTGGGTGAACCTGGTGACTGACGGCTTGCCTGCCACCGCTCTAGGCTTCAACCCCCCTGATCTGGACATCATGAACAAGCCCCCCCGAAGCGCCAAAGAGCCCCTCATCTCCGGATGGCTCTTTTTCAGATACTTGGCCATCGGCTGTTATGTGGGTGCTGCTACTGTAGGAGCTGCAGCCTGGTGGTTCATTGTTGCTGATGATGGTCCAATGATCACACTTTACCAGCTGAGTCATTTCCTGCAGTGTTCTCCCGATAATCCTGACTTCCAGGACTTGGAGTGTCACGTCTTCGAGTCTCCTTACCCCATGACCATGGCCCTGTCTGTGCTCGTCACCATTGAGATGTGCAACGCCCTCAACAGTCTATCCGAGAACCAGTCTCTGGTGCGCATGCCACCCTGGGAGAATATCTGGCTGCTGGGAGCCATCTGTCTCTCCATGTCTCTGCACTTCCTCATCCTCTATGTGGAGCCACTGCcgGTCATCTTCCAGATCACTCCTCTGAATGTGACGCAGTGGATGATGGTGCTGAAGATCTCGCTGCCTGTCATTCTCTTGGACGAGCTGCTCAAATTTGTGGCGAGGACCTACCTGGAGCCTGGTAAAGACCTGAAGGAGGAAAAGGAGGACAGGAGAGGCTGGTCCTTCTCTGCATGCACTGACGGCGTCTCCTGGCCCTTCATAGCTCTCACACTCCCTCTGGTGGTGTGGCTGTACAGCACTAACATAACCCAGCTCTTCCGGCACTCCTGACTGATCCCAGACCTGACTCCAAATAACCAGAGACACAACATTCATTAACAAGGAGCA

Function

symbol description
atp2a2a Predicted to enable P-type calcium transporter activity. Acts upstream of or within heart looping and regulation of heart contraction. Predicted to be located in membrane and sarcoplasmic reticulum. Predicted to be active in sarcoplasmic reticulum membrane. Predicted to be integral component of membrane. Is expressed in cardiovascular system; musculature system; pectoral fin; polster; and somite. Human ortholog(s) of this gene implicated in acrokeratosis verruciformis; essential hypertension; keratosis follicularis; and pulmonary hypertension. Orthologous to human ATP2A2 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2).

GO:

id name namespace
GO:0070588 calcium ion transmembrane transport biological_process
GO:0008016 regulation of heart contraction biological_process
GO:0006811 ion transport biological_process
GO:0006816 calcium ion transport biological_process
GO:0001947 heart looping biological_process
GO:0006874 cellular calcium ion homeostasis biological_process
GO:0005783 endoplasmic reticulum cellular_component
GO:0033017 sarcoplasmic reticulum membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005388 calcium transmembrane transporter activity, phosphorylative mechanism molecular_function
GO:0005524 ATP binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0008553 proton-exporting ATPase activity, phosphorylative mechanism molecular_function
GO:0016887 ATPase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040426-702 Predicted to enable P-type calcium transporter activity. Acts upstream of or within heart looping and regulation of heart contraction. Predicted to be located in membrane and sarcoplasmic reticulum. Predicted to be active in sarcoplasmic reticulum membrane. Predicted to be integral component of membrane. Is expressed in cardiovascular system; musculature system; pectoral fin; polster; and somite. Human ortholog(s) of this gene implicated in acrokeratosis verruciformis; essential hypertension; keratosis follicularis; and pulmonary hypertension. Orthologous to human ATP2A2 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2).

Ensembl:

ensembl_id ENSDARG00000029439

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00069611 False 3724 mRNA 0.51 22 11687254 11744994
TCONS_00069612 False 798 nonsense_mediated_decay 0.47 6 11687257 11715282
TCONS_00069613 True 3186 mRNA 0.54 20 11687586 11740478

Neighbor

gene id symbol gene type direction distance location
XLOC_035483 ift81 coding upstream 5695 11642070 ~ 11681559 (+)
XLOC_035482 NA coding upstream 113782 11567232 ~ 11573472 (+)
XLOC_035481 tjp2b coding upstream 144965 11425048 ~ 11542289 (+)
XLOC_035480 fxn coding upstream 347647 11325310 ~ 11339607 (+)
XLOC_035479 NA coding upstream 367551 11319434 ~ 11319703 (+)
XLOC_035485 NA coding downstream 49664 11794658 ~ 11812164 (+)
XLOC_035486 CR933523.1 coding downstream 115034 11860028 ~ 11860144 (+)
XLOC_035487 ntng2a coding downstream 248156 11993150 ~ 12111461 (+)
XLOC_035488 endog coding downstream 373103 12118097 ~ 12122228 (+)
XLOC_035489 NA coding downstream 1021036 12766030 ~ 13063138 (+)
XLOC_035478 NA non-coding upstream 574687 11105506 ~ 11112567 (+)
XLOC_035476 NA non-coding upstream 737071 10901547 ~ 10950183 (+)
XLOC_035474 FP085410.1 non-coding upstream 843186 10843952 ~ 10844068 (+)
XLOC_035498 NA non-coding downstream 1773528 13518522 ~ 13597892 (+)
XLOC_035499 NA non-coding downstream 1942110 13687104 ~ 13692006 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000010_07320443_07334877 ATP2A2.S, ATP2A2B, ATP2A2A, ATP2A2 coding CI01000010 null 7319816 ~ 7334993 (-)
bowfin (Amia calva) AMCG00018902 LOC103365013,LOC102776280 coding CM030135.1 CM030135.1 25171485 ~ 25188842 (+)