XLOC_035517 (soat1)


Basic Information

Item Value
gene id XLOC_035517
gene name soat1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007119.7
NCBI id CM002892.2
chromosome length 54304671
location 14886452 ~ 14910223 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00069662
CTGAGTTTGTCTTCATACACCGAATTGTTCAATTAGGAGGTGTATATTTGGAACAACACACGGCAGCAGGATGGTGAATGAGGGTGCTGGAGGCCCTCGCAGTCGCAAGAGCTCTCATAAGGTGGCTTCGTCATCAGACAAGGATGGACCTGAAAGAGACGCAGAAGAGTTTCCTCTCTCTAGCAATGGAAAAGTGGAGGTGGAGCAGATTATTAGTGCAAAACTCCAGCTGAAGAAGAAAGCTGAGCATTTGAAAGCAGACCTGATGAGGCAGTTTGACGCTCAAGTGAATGAGTTCATGGACAGCCTGATAGAGGAGTCTGCCAGTCTGGGCTCTTCGCATGTCAGCACAGTCTTTCCTCTGTCAGATAAGGAGAAAAGCAAACTCAGGAATGCACAACCTTCCCAAGGCCAGAGCAAGCAGTTTGTGATTCGCCGTTCACTGTTAGATGATCTGTTTGAGGTGAACCACATCCGCACTATCTATCACATGTTCATCGCTCTGCTCATTCTGTTCATCTTCAGCACGCTCGTCGTGGACTTCATCGATGAGGGCAGACTGGTGCTGGAGTTTGACCTGTTGGTGTATGCGTTTGGCCAGTTCCCTCTAGTGGTTGTGACGTGGATGTGTATGTTCCTGTCCACACTTGTCGTTCCATATGTTCTGCTGGTTGTCTGGGCCGGTATTTACTCCTCTTCACAGCATCGGTTGTTATGGACAGTGCTGGCTGGTTCTATCCTGCTCATCTACCAGGGGCTGGGTTTGGGTTTCCTTCCCACATATGTGGTGCTGAAGAACGGCCTTCCCCCTGCTTCATGCTTCATACTGATTCTAGAACAGGTGCGACTGATGATGAAGTCTCACTCTTTCATCAGGGAAAATGTGCCAAGAGTCCGATCCTTAGATCGAAATAAATCAAatttaGTAGCTGTTCCTCAGTTCACCCAGTACATCTACTTTCTTTTTGCACCCACACTAATATACAAGGACAATTATCCACGAAATCCCTGTATTCGGTGGGGTTACGTGGCTACAAAGTTTTCTCAGGTGCTGGGcagtttattttatgcatattacaTATTTGTGCGGCTGTGTATCCCTCAGTTTCGCAATATCAGCATGCAGCTCTTCGACCCGAGGGCCATGGTGCTGTGCGTCTTCAACTCCATACTGCCAGGAGTGCTTGTGCTTTTCCTGGCATTCTTTGCTTTTCTGCATTGCTGGCTTAATGCATTTGCTGAAATGCTACGATTTGGAGACCGAATGTTTTATAAGGACTGGTGGAACTCCACTTCATATGCAAACTATTATCGCACATGGAATGTTGTAGTTCATGACTGGCTTTATTACTATGTCTACAGGGACTTCCTGTGGATGACACAGAAGCGGTTTCGTGCGGTGGCCATGCTGGTTGTGTTTACCGTGTCTGCTGTAGTACACGAGTATGTTCTGGCCATCTGCTTCGGCTTCTTCTACCCCGTCATGTTCTGCCTCTTCATGTGCTTTGGAATGGTGTTTAACTTCGTCCTTCATGACCGGAGGAAAGGACCGATCTGGAACGTGATTATGTGGACGTCTCTGTTCTTGGGACAGGGGGTAATGATCTGCCTGTATTCTCAAGAGTGGTACGCACAACGCTACTGTCCCATTGAGGAGCCTTCCTTGATTGACCTGCTGAAGCCTCGATCCTGGACTTGTTATCCACAGACTAACGCTGCTTTTGACTCTCACTGAATGGGATTAACACAGAAGAACATTCTTTAGGTATTGCACTATGAGTGAAAAATGAAAATCACGAAGACAATGTTTTATGATGGGGCCTTAGATATGTTATTTGTTgagatattatttattatgacagcCGTAACAGAATGTGGAACGTCTATAATGTTTCAATAGTTTAGTCTAGTTAGCATTTGACAATCTATTTTAGGTTCAATCTGATCTGGCTTAAAGAGATTCTATTTTTAGACGCCTTTGTGATGTCATGAAGTTGAGATCAGATTTAGTTTACTGccgttttatttagatttttagtaTTTGATACTGTTGTGTTATTCCATGGACTTAAAGAGTGAATATGTGGT
>TCONS_00069663
ATGGTGAATGAGGGTGCTGGAGGCCCTCGCAGTCGCAAGAGCTCTCATAAGGTGGCTTCGTCATCAGACAAGGATGGACCTGAAAGAGACGCAGAAGAGTTTCCTCTCTCTAGCAATGGAAAAGTGGAGGTGGAGCAGATTATTAGTGCAAAACTCCAGCTGAAGAAGAAAGCTGAGCATTTGAAAGCAGACCTGATGAGGCAGTTTGACGCTCAAGTGAATGAGTTCATGGACAGCCTGATAGAGGAGTCTGCCAGTCTGGGCTCTTCGCATGTCAGCACAGTCTTTCCTCTGTCAGATAAGGAGAAAAGCAAACTCAGGAATGCACAACCTTCCCAAGGCCAGAGCAAGCAGTTTGTGATTCGCCGTTCACTGTTAGATGATCTGTTTGAGGTGAACCACATCCGCACTATCTATCACATGTTCATCGCTCTGCTCATTCTGTTCATCTTCAGCACGCTCGTCGTGGACTTCATCGATGAGGGCAGACTGGTGCTGGAGTTTGACCTGTTGGTGTATGCGTTTGGCCAGTTCCCTCTAGTGGTTGTGACGTGGATGTGTATGTTCCTGTCCACACTTGTCGTTCCATATGTTCTGCTGGTTGTCTGGGCCGGTATTTACTCCTCTTCACAGCATCGGTTGTTATGGACAGTGCTGGCTGGTTCTATCCTGCTCATCTACCAGGGGCTGGGTTTGGGTTTCCTTCCCACATATGTGGTGCTGAAGAACGGCCTTCCCCCTGCTTCATGCTTCATACTGATTCTAGAACAGGTGCGACTGATGATGAAGTCTCACTCTTTCATCAGGGAAAATGTGCCAAGAGTCCGATCCTTAGATCGAAATAAATCAAatttaGTAGCTGTTCCTCAGTTCACCCAGTACATCTACTTTCTTTTTGCACCCACACTAATATACAAGGACAATTATCCACGAAATCCCTGTATTCGGTGGGGTTACGTGGCTACAAAGTTTTCTCAGGTGCTGGGcagtttattttatgcatattacaTATTTGTGCGGCTGTGTATCCCTCAGTTTCGCAATATCAGCATGCAGCTCTTCGACCCGAGGGCCATGGTGCTGTGCGTCTTCAACTCCATACTGCCAGGAGTGCTTGTGCTTTTCCTGGCATTCTTTGCTTTTCTGCATTGCTGGCTTAATGCATTTGCTGAAATGCTACGATTTGGAGACCGAATGTTTTATAAGGACTGGTGGAACTCCACTTCATATGCAAACTATTATCGCACATGGAATGTTGTAGTTCATGACTGGCTTTATTACTATGTCTACAGGGACTTCCTGTGGATGACACAGAAGCGGTTTCGTGCGGTGGCCATGCTGGTTGTGTTTACCGTGTCTGCTGTAGTACACGAGTATGTTCTGGCCATCTGCTTCGGCTTCTTCTACCCCGTCATGTTCTGCCTCTTCATGTGCTTTGGAATGGTGTTTAACTTCGTCCTTCATGACCGGAGGAAAGGACCGATCTGGAACGTGATTATGTGGACGTCTCTGTTCTTGGGACAGGGGGTAATGATCTGCCTGTATTCTCAAGAGTGGTACGCACAACGCTACTGTCCCATTGAGGAGCCTTCCTTGATTGACCTGCTGAAGCCTCGATCCTGGACTTGTTATCCACAGACTAACGCTGCTTTTGACTCTCACTGA

Function

symbol description
soat1 Predicted to enable cholesterol O-acyltransferase activity; cholesterol binding activity; and fatty-acyl-CoA binding activity. Predicted to be involved in cholesterol efflux; cholesterol esterification; and cholesterol metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including eye; hatching gland; pericardial region; pleuroperitoneal region; and yolk syncytial layer. Human ortholog(s) of this gene implicated in Chagas disease; coronary artery disease; and hepatocellular carcinoma. Orthologous to several human genes including SOAT1 (sterol O-acyltransferase 1).

GO:

id name namespace
GO:0034435 cholesterol esterification biological_process
GO:0008203 cholesterol metabolic process biological_process
GO:0033344 cholesterol efflux biological_process
GO:0005783 endoplasmic reticulum cellular_component
GO:0005789 endoplasmic reticulum membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0015485 cholesterol binding molecular_function
GO:0016740 transferase activity molecular_function
GO:0034736 cholesterol O-acyltransferase activity molecular_function
GO:0000062 fatty-acyl-CoA binding molecular_function
GO:0016746 transferase activity, transferring acyl groups molecular_function
GO:0008374 O-acyltransferase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-081105-177 Predicted to enable cholesterol O-acyltransferase activity; cholesterol binding activity; and fatty-acyl-CoA binding activity. Predicted to be involved in cholesterol efflux; cholesterol esterification; and cholesterol metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including eye; hatching gland; pericardial region; pleuroperitoneal region; and yolk syncytial layer. Human ortholog(s) of this gene implicated in Chagas disease; coronary artery disease; and hepatocellular carcinoma. Orthologous to several human genes including SOAT1 (sterol O-acyltransferase 1).

Ensembl:

ensembl_id ENSDARG00000062297

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00069662 False 2088 mRNA 0.45 16 14886452 14910223
TCONS_00069663 True 1665 mRNA 0.48 15 14890821 14909870

Neighbor

gene id symbol gene type direction distance location
XLOC_035516 si:dkey-21p1.3 coding upstream 2760 14855471 ~ 14883692 (+)
XLOC_035514 cacna1ea coding upstream 58002 14710542 ~ 14828450 (+)
XLOC_035515 CR450798.1 coding upstream 80162 14806174 ~ 14806290 (+)
XLOC_035513 NA coding upstream 233802 14612986 ~ 14652650 (+)
XLOC_035512 NA coding upstream 325022 14558645 ~ 14561430 (+)
XLOC_035518 abl2 coding downstream 5109 14915332 ~ 14985276 (+)
XLOC_035519 fnbp1l coding downstream 76610 14986833 ~ 15080573 (+)
XLOC_035520 paox1 coding downstream 329326 15239549 ~ 15250265 (+)
XLOC_035521 zgc:171480 coding downstream 341225 15251448 ~ 15253800 (+)
XLOC_035522 slc5a9 coding downstream 344341 15254564 ~ 15268932 (+)
XLOC_035511 BX294388.1 non-coding upstream 470629 14415698 ~ 14415823 (+)
XLOC_035509 NA non-coding upstream 640099 14241585 ~ 14246353 (+)
XLOC_035525 BX510319.1 non-coding downstream 566402 15476625 ~ 15479807 (+)
XLOC_035527 NA non-coding downstream 1349363 16259586 ~ 16265811 (+)
XLOC_035529 NA non-coding downstream 1653730 16563953 ~ 16582042 (+)
XLOC_035530 NA non-coding downstream 1660113 16570336 ~ 16577809 (+)
XLOC_035531 NA non-coding downstream 1699455 16609678 ~ 16613471 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000010_05627867_05634808 SOAT1 coding CI01000010 null 5626570 ~ 5634808 (-)