XLOC_036460 (hspa1b)


Basic Information

Item Value
gene id XLOC_036460
gene name hspa1b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007119.7
NCBI id CM002892.2
chromosome length 54304671
location 24968098 ~ 24970790 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00071243
AGACGAGAAAACACGACTCGAGCAACCCGAAACAGAGCTGAAATCCGCTCTCTAAAGCGACTGAAGAAACTCACAAGACCTGTGATTTTAACAATCAAAGATGGCTAAAGGTTTGTCTATTGGCATTGATCTGGGAACCACTTACTCCTGTGTTGGAGTGTTCCAGCATGGCAAAGTGGAGATCATCGCTAACGATCAAGGAAACCGAACCACTCCAAGCTATGTGGCTTTTACAGACACAGAAAGACTCATCGGAGATGCTGCCAAAAACCAAGTCGCCATGAACCCCAACAACACCATCTTTGACGCCAAACGACTGATTGGCAGAAAGTTTGATGATCAGGTTGTCCAGTCTGACATGAAGCTTTGGCCATTTAAGGTCATCAGTGAAGATGGCAAACCAAAAGTTCAAGTCGAGTACAAAGGGGAAAACAAGACATTCTACCCTGAGGAGATCTCATCTATGGTCCTGGTCAAAATGAGAGAGATTGCCGAAGCCTACCTGGGTCATAGAGTCAATAATGCTGTCATCACAGTCCCAGCGTACTTCAACGATTCACAGAGGCAAGCGACCAAAGACGCAGGGGTCATTGCCGGATTGAACGTGCTGCGAATTATCAATGAGCCCACAGCAGCTGCCATCGCCTACGGCCTGGACAAGGGCAGGAAGGGAGAGAGGAATGTCCTGATCTTCGACCTCGGCGGAGGCACCTTTGATGTCTCCATCCTGACGATTGAGGATGGGATCTTTGAAGTGAAAGCCACAGCAGGGGACACTCATCTGGGTGGAGAGGACTTCGACAATCGCATGGTGAAGCACTTTGTTGAAGAGTTTAAGAGGAAGCACAAGAAGGACATCAGTCAGAATAAGAGAGCAGTAAGACGGCTGCGCACGGCCTGCGAGAGAGCTAAAAGGACCCTCTCATCTAGCTCTCAGGCTAGCATCGAGATCGATTCCCTCTTTGAAGGCATCGATTTCTACACTTCCATCACTAGGGCTCGCTTTGAAGAGCTTAACGCGGAGCTCTTTAGAGGCACGCTGGATCCAGTGGAAAAGGCTTTGAGAGATGCCAAAATGGACAAGTCTCAGATCCAAGATATTGTTCTGGTTGGCGGCTCCACCAGGATCCCCAAGATACAGAAGCTCCTGCAGGACTTCTTCAATGGAAGGGATCTCAACAAAAGCATCAACCCAGATGAGGCAGTGGCGTATGGAGCGGCGGTGCAGGCTGCCATCCTGATGGGTGATACCTCGGAAAATGTCCAGGACTTGTTGCTTCTGGATGTGGCTCCGTTGTCCCTGGGAATCGAGACGGCTGGAGGAGTCATGACTGCACTCATCAAACGTAACACCACCATCCCCACCAAGCAGACGCAGATCTTCTCCACATATTCCGATAACCAGCCGGGAGTCCTGATCCAGGTGTTTGAAGGAGAGAGGGCTATGACCAAAGATAACAATTTGCTTGGCAAGTTTGACCTTACTGGGATCCCACCAGCACCACGTGGTGTACCTCAAATAGAGGTGACCTTCGACATTGATGCCAATGGAATTCTTAACGTATCCGCTGCCGACAAGAGCACGggaaaagagaacaaaatcactaTAACCAATGACAAAGGTCGACTGAGCAAGGAGGATATCGAGCGTATGGTGCAAGATGCGGAAAAGTACAAAGCCGAGGATGAAGTGCAGAGAGAGAAGATCGCAGCAAAGAACGCTCTGGAGTCTTACGCCTTCAGTATGAAGAACACTGTTGAAGATGAGAACCTGAGGGGAAAGATCAGCGAACAGGATAAGAAGAAGATCATTGATAAGTGTACAGAGGTCGTTTCTTGGTTGGAGAACAATCAGCTGGCTGAAAAGGAAGAGTATGAGCATCATCAGAAGGAACTGGAAAGTGTGTGCAATCCAATCATCTCGCGGCTGTATCAGGGAGGAGCTCCTCCTGCAGGTGGATGTGGATTCCAAGCCCAGCCTGAATCATCACAGGGCCCCACCATTGAAGAGGTGGACTAG

Function

symbol description
hspa1b Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and misfolded protein binding activity. Predicted to be involved in several processes, including cellular response to unfolded protein; chaperone cofactor-dependent protein refolding; and protein refolding. Predicted to be active in cytosol; nucleus; and plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; autoimmune disease of musculoskeletal system (multiple); cystic fibrosis; schizophrenia (multiple); and vascular dementia. Orthologous to several human genes including HSPA1L (heat shock protein family A (Hsp70) member 1 like).

GO:

id name namespace
GO:0006986 response to unfolded protein biological_process
GO:0016192 vesicle-mediated transport biological_process
GO:0034620 cellular response to unfolded protein biological_process
GO:0051085 chaperone cofactor-dependent protein refolding biological_process
GO:0042026 protein refolding biological_process
GO:0008180 COP9 signalosome cellular_component
GO:0005829 cytosol cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005524 ATP binding molecular_function
GO:0044183 protein folding chaperone molecular_function
GO:0051787 misfolded protein binding molecular_function
GO:0031072 heat shock protein binding molecular_function
GO:0031625 ubiquitin protein ligase binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0016887 ATPase activity molecular_function
GO:0051082 unfolded protein binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-060503-867 Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and misfolded protein binding activity. Predicted to be involved in several processes, including cellular response to unfolded protein; chaperone cofactor-dependent protein refolding; and protein refolding. Predicted to be active in cytosol; nucleus; and plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; autoimmune disease of musculoskeletal system (multiple); cystic fibrosis; schizophrenia (multiple); and vascular dementia. Orthologous to several human genes including HSPA1L (heat shock protein family A (Hsp70) member 1 like).

Ensembl:

ensembl_id ENSDARG00000056210

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00071243 True 2020 mRNA 0.49 2 24968098 24970790

Neighbor

gene id symbol gene type direction distance location
XLOC_036459 kcnc4 coding downstream 2790 24928632 ~ 24965308 (-)
XLOC_036458 NA coding downstream 59059 24856986 ~ 24909039 (-)
XLOC_036457 BX324132.3 coding downstream 164987 24799688 ~ 24803111 (-)
XLOC_036456 rbm15 coding downstream 177038 24788499 ~ 24791060 (-)
XLOC_036455 NA coding downstream 187110 24780407 ~ 24780988 (-)
XLOC_036461 ahcyl1 coding upstream 1100 24971890 ~ 25011157 (-)
XLOC_036462 nfyal coding upstream 48752 25019542 ~ 25034411 (-)
XLOC_036463 sort1b coding upstream 70923 25041713 ~ 25074319 (-)
XLOC_036464 amigo1 coding upstream 146600 25117390 ~ 25120231 (-)
XLOC_036465 gnat2 coding upstream 254800 25225590 ~ 25247284 (-)
XLOC_036447 NA non-coding downstream 390530 24325248 ~ 24577568 (-)
XLOC_036468 NA non-coding upstream 424316 25395106 ~ 25396501 (-)
XLOC_036474 BX544876.1 non-coding upstream 760222 25731012 ~ 25734935 (-)
XLOC_036481 NA non-coding upstream 1148433 26119223 ~ 26326501 (-)
XLOC_036482 NA non-coding upstream 1244894 26215684 ~ 26229796 (-)
XLOC_036483 NA non-coding upstream 1358463 26329253 ~ 26368366 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000052_01925657_01927599 HSPA6, HSP70B, HSP70A, HSP70.1, HSP70-5, HSP70.3, HSP70.2, HSP70L coding CI01000052 null 1925657 ~ 1927781 (+)