XLOC_036596 (mhc2bl)


Basic Information

Item Value
gene id XLOC_036596
gene name mhc2bl
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007119.7
NCBI id CM002892.2
chromosome length 54304671
location 36362898 ~ 36370595 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00071475
ATGTCACTGCTTAGGCTTTTCTATGGTCATCTCATATTGACGTTGTCTGTATTAATTGGAGCTGAAACAGCTAATGTATATTACAGATACACTTGGATACAATGCATCTCCAGCTCTAAAAATCTTAGTGACATGGTGTTTATTGAGAGcctttatttcaataaatatctATTTACACAGTTTAATAGTAATATTGGAAAGTATGTGGGGTTTAGTGAGTACGGCATTAGAAATGCAGAATTTAGGAACAATGACACCAATTTActgcttaaaaaaaaagctgCGGTGAACAAAGTCTGCAAAAATAATGCTATCAACCATGACAAATTTATTCGCAATAAAGCAGTGAAACCAAAGGTTAAGCTCACTTTAGTGAAGCCAGCTGGTGGAAGACATCCTGCAGTTTTGATGTGCAGCGCGTATGAATTTTATCCTCCACACATCAGAGTGTACTGGCTGAGAAATGGTGAAGTGATAACCTCTGATGTGACATCAACTATGGAGATGGCTGATGGAGACTGGTATTACCAGATTCACTCTGAGCTGGAGTACAGCCCAAAATCTGGAGAAAGGATCTCATGTGGGATTGAACATGCCAGCTCTAATAAACCCATCATTACAGAGTGGGATTCATCTCGTCCTGCGTCTGAGAGGAATAAAATCGCCATTGGGGCATCTGGTGTAGTTCTGGGAATCATCATCCCAGctatatgttttatttactaCAAGAAAACTGCAGAAGCAGTTTTGTGATGCTACAACTATGAGTGGATATCTTGCCTGACagaaaacggcaaagaaacacCTCATTGCTGAgtactatataaataataacTGTGCGGTAATTCATTTTTACAATACACTACACTCTCTCCAAGAAGGCCCAAACTCAATTAGCAAAGACTTTGTTCAGTGATCCCTAACATGCATTTAGCAAGGGTGGAAATGGGATGCTGCTGTTTTAGCTAACAAATTTAAGCATTATAAACATAATATTATGAACTTTGCACTGATTTGCTTTGATGTCATGATTATTTAATTGTTGTAAAACCAATGTTCtttatgtttattataatcaTTCTGGTGCAGGGAAAactatttacaatgttttaattaaaacaatataataattttaaatgaatgtttttttgtgcgttttttttttttttttttgtaatatatgctGTAGTTAATCTATGTGTGTTACTAAGATAAATTTGAACACCAACCTTGTCAAGTTTTGGATAGTGACTCAGGAATGACATATTACAACCAGTAGGCTATGGGGAAAGTTTTTAGCAGCACTCTGTAAGAAATTGCAGCAGAAACATGCAAAACCGGATCTACAAGACAAGAGAGAAACAGTACATGGCTTGCAAGAAATCCCATCTTAAACTGtagtgctattttgggatttccgtcTAGATTTTGCCTACTCAATTTTAAAAGCTTCCCAAGCCACATGCAGAGGTATACATTTGGTGTAATTTATTTTGGTGGTTCCAACATATGTCTGTAGTCATAGGAAAAAAATTCATATACCATAGACTaggcaaaagttattgtatatagtgttgtgaaaaggaatagcaactttacaaagtaataaatgatttattgttcCAACTTTTTTGACAGGTGTTGCAAGAAAGGTATGTTTATAACGCTGAAGAAGTAATCAACTCAACCATGTGATTTCTGTATGAGGAAGTTTCACAAACCAAAATGCTTGGtgcagatttgttttgtttatgttagtcaTGGAGCACTGAGAATTGTCAAAACTGGTTTAGTATGAATGCATACTGGTTTAGTATGAATGAGACCTACTTTAACAGGTTCTTTTGCAATTACCTTGAAGCACTgagtaaacagttttttttttttgcaaataccAACAagctttctatatttttataattctgaAAGTAAAGTAATTCCACTGTTTTTATAAGCAATTTTGCCAGGCAGAACCTTTTAATAAGGTCCATaatgttgcataaaacatatttcaCTAATAAAGTTTTCATCAAATCACACCCTTCTGTAAAAACATTATCACTTTGAGGCAACTTGCTTAACTACCATCTtgtttaagaaagaaagaaagaaagaaagaaagaaagaaagaaacaaagaaagaaagaaagaccttGCTTTATCAGAAAGTTAAGATTGCCATCTTGTGGTTGGtaataattattgaaaaagtaAAACAGCATTGGATCAACAATGAAGAGGCCAAAACGTTATTGAAAACTTGTTGCATTTCTATcaggtttgttcatgttttaggaaACTTTAAAAACTAGGTTCTGTTACTTTGATGGACATCAAATTGCAAATGTTATTACAATTGCAATAACTCTTATTGCACAAcaccaatcattcattcattttctttttggcttagtccctttattaatccagggtggccacagtggaatgaaccgccaacttatccagcacatgttttagacagcgaatgcccttccagctgaaacccatctctgggaaacattatgCTATTATTTCTGCATGAGCaattatatcattaaataaaatgGCCTCACAATATATTCTGGGACAAAAAAGGATGTATTagtaaaaaaaaggtttggaaccactgcATTAGAGGACAACAAGTCCAGGGCACATTTACTCTGGACGATGGAACGGTGTGGAATGCTGTTCACCTGTTACCAGTTCACTTTTGTCCTGAACAAAGAAACTCAGATAATGAATTTTCAGGTGTCTCAAAGTTAGTTGTAGTACCAAAAAAATCAAAGACATCCCAGAACCAGACGTCTACCAATTTCGCACAAAGTCTTTAGGTGTACTCATACTAGGCACGGTTGTCTTGAACTGTTCCCAGGCTTGATTGTTCCCCCTCCCCTCTCCCCCTTGGCCTGCACTTACATTGCATTTTTTTGCCTTTCGAGCCCGAAaacgcttacgtcatcaatgataTGACTATTTAGTTTTACTGTACtgtggacattgctttagttataatattttgtattatttcagGTCGTTTAATATGCAGTGACATACAGTCGAATCTTTTACTGAACAGATctaccacttttgacgctcataaatgttcATGAAAGTCACTGTGCTGCACGTAttatgaggtttgctgaaggtgcagctgtcatgcagcaAGGGGattgtatctttaataaactatgacagacTGTAttcattgaaaaaataaaaaaagattaataaaccCATATGAAACACTCCCTTTAAAGTGACGTCAGGTCTTTAGTTTCATACTCAGTCTCGCTTTGCACTCATAGTACACTCACAGAAGGTTTGTAGTTTGCAGCATTCacgacatgatttgtaccatgggaaaccaaaacgaacctttagtttttaaaacctgcagatacaatattgtaccttcatcaaaaaaaatctaatctggTTCATGAAGGTAGCACTaaagtgacaagacactttgtaccttaacagtgtaaaatgtgttcctt
>TCONS_00071476
AGATTTTTGGGCAAGATTCAGCAGATATTCAGAGCGAGTGAAAATGTCACTGCTTAGGCTTTTCTATGGTCATCTCATATTGACGTTGTCTGTATTAATTGGAGCTGAAACAGCTAATGTATATTACAGATACACTTGGATACAATGCATCTCCAGCTCTAAAAATCTTAGTGACATGGTGTTTATTGAGAGcctttatttcaataaatatctATTTACACAGTTTAATAGTAATATTGGAAAGTATGTGGGGTTTAGTGAGTACGGCATTAGAAATGCAGAATTTAGGAACAATGACACCAATTTActgcttaaaaaaaaagctgCGGTGAACAAAGTCTGCAAAAATAATGCTATCAACCATGACAAATTTATTCGCAATAAAGCAGTGAAACCAAAGGTTAAGCTCACTTTAGTGAAGCCAGCTGGTGGAAGACATCCTGCAGTTTTGATGTGCAGCGCGTATGAATTTTATCCTCCACACATCAGAGTGTACTGGCTGAGAAATGGTGAAGTGATAACCTCTGATGTGACATCAACTATGGAGATGGCTGATGGAGACTGGTATTACCAGATTCACTCTGAGCTGGAGTACAGCCCAAAATCTGGAGAAAGGATCTCATGTGGGATTGAACATGCCAGCTCTAATAAACCCATCATTACAGAGTGGGATTCATCTCGTCCTGCGTCTGAGAGGAATAAAATCGCCATTGGGGCATCTGG

Function

symbol description
mhc2bl Predicted to enable MHC class II protein complex binding activity. Predicted to be involved in antigen processing and presentation of exogenous peptide antigen via MHC class II; peptide antigen assembly with MHC class II protein complex; and positive regulation of T cell activation. Predicted to act upstream of or within antigen processing and presentation and immune response. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of MHC class II protein complex. Human ortholog(s) of this gene implicated in several diseases, including Hantavirus hemorrhagic fever with renal syndrome; acute disseminated encephalomyelitis; asthma (multiple); hepatitis B; and lung disease (multiple). Orthologous to human HLA-DPB1 (major histocompatibility complex, class II, DP beta 1); HLA-DQB2 (major histocompatibility complex, class II, DQ beta 2); and HLA-DRB5 (major histocompatibility complex, class II, DR beta 5).

GO:

id name namespace
GO:0006955 immune response biological_process
GO:0019882 antigen processing and presentation biological_process
GO:0042613 MHC class II protein complex cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component

KEGG: NA

ZFIN:

id description
ZDB-GENE-030616-99 Predicted to enable MHC class II protein complex binding activity. Predicted to be involved in antigen processing and presentation of exogenous peptide antigen via MHC class II; peptide antigen assembly with MHC class II protein complex; and positive regulation of T cell activation. Predicted to act upstream of or within antigen processing and presentation and immune response. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of MHC class II protein complex. Human ortholog(s) of this gene implicated in several diseases, including Hantavirus hemorrhagic fever with renal syndrome; acute disseminated encephalomyelitis; asthma (multiple); hepatitis B; and lung disease (multiple). Orthologous to human HLA-DPB1 (major histocompatibility complex, class II, DP beta 1); HLA-DQB2 (major histocompatibility complex, class II, DQ beta 2); and HLA-DRB5 (major histocompatibility complex, class II, DR beta 5).

Ensembl:

ensembl_id ENSDARG00000074510

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00071475 False 3506 mRNA 0.36 5 36362898 36370552
TCONS_00071476 True 723 mRNA 0.40 4 36368530 36370595

Neighbor

gene id symbol gene type direction distance location
XLOC_036595 zgc:103700 coding downstream 35570 36321336 ~ 36327328 (-)
XLOC_036594 si:busm1-194e12.11 coding downstream 75852 36283548 ~ 36287046 (-)
XLOC_036593 CT583723.2 coding downstream 222493 36128477 ~ 36140405 (-)
XLOC_036592 TMEM132D coding downstream 237049 36057318 ~ 36125849 (-)
XLOC_036591 slc15a4 coding downstream 401911 35809081 ~ 35960987 (-)
XLOC_036597 si:zfos-2070c2.1 coding upstream 6411 36377006 ~ 36387387 (-)
XLOC_036598 si:zfos-2070c2.3 coding upstream 27223 36397818 ~ 36412936 (-)
XLOC_036599 mhc2dab coding upstream 96176 36466771 ~ 36469117 (-)
XLOC_036600 mhc2a coding upstream 101849 36472444 ~ 36475328 (-)
XLOC_036601 CU694380.2 coding upstream 157638 36528233 ~ 36541856 (-)
XLOC_036590 NA non-coding downstream 582211 35766632 ~ 35780687 (-)
XLOC_036588 NA non-coding downstream 770390 35579388 ~ 35592508 (-)
XLOC_036587 BX322651.1 non-coding downstream 986541 35376243 ~ 35376357 (-)
XLOC_036584 BX005399.13 non-coding downstream 1900507 34461160 ~ 34462391 (-)
XLOC_036582 BX511073.1 non-coding downstream 2030322 34271072 ~ 34332576 (-)
XLOC_036604 NA non-coding upstream 362321 36732916 ~ 36983161 (-)
XLOC_036605 NA non-coding upstream 423906 36794501 ~ 36798705 (-)
XLOC_036606 NA non-coding upstream 606403 36976998 ~ 36978006 (-)
XLOC_036614 NA non-coding upstream 1595553 37966148 ~ 37966860 (-)

Expression


Co-expression Network