XLOC_036820 (tlr9)


Basic Information

Item Value
gene id XLOC_036820
gene name tlr9
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007119.7
NCBI id CM002892.2
chromosome length 54304671
location 53730368 ~ 53735399 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00071877
TGCACACAAAATGGCTGGTCTAGTGTTAAAGCGagggtaaaaaaaaagttaaagcaaATAATAGACTTTTCTGATATTCGTATTCTCATTTCCAGGCCATGTTTGGACCAATGGTGTCCTTGATTCTGCTTCTGAATCAGTTCCAACTCTTCGCAGCTTCACATCCTCAGTTTTATCCGTGTGAAAGTCACTTCACCAAAGACGGACACATAAATGTGGACTGCCAGCACAGACGGCTCTCTAAAGTCCCCAGGTTCACTTCTCCCTCAGTTATATCACTCAACCTGAATAACAACCATATACACCGCATTAAAGGGGATGCATTTTCTGGTCTACCCAATCTCAAGTATCTCAGCCTGATGTGGAACTGTATATCAGACCGTCTTAAGGAGGCAAGATGGCCGTTATGCAGTGTGAATATTGACCCGGATGCATTTGTTGGACTGAAAAACCTCACTTCCCTTCAGTTAGCTGGGAACAGCTTGAAGATGATTCCTCCTCTGCCAAAGCAGCTTGAAGTCCTGGGACTGGAAttcaacaatatttttaatatcgTCAAACCTTTAGGCACACCACAACTAAAGCAACTGCTGCTAAGCAAGAACTGTTTCTACGCAAACCCATGCCACCAGCCTTACTTTATCAACTCAAGTGTGTTTCAGGATCTTCCTGAGCTTTTGAACCTCACCCTTAGTTACAACAACTTGACTGCCATTCCCTCGTATCTTCCAGGTTCACTAGAAAGTCTAGACTTGCGAGAGAATACAATTGATCACATCAATAAAGAGTCCTTTGCAAATCTCAGAAATCTGCGACATCTCAACCTGGGGTGGAACTGCCAAAGGTGCGACCACGCTTCTGATCCCTGCTTCCCATGCCCAAACAACCAGTCTCTGGATCTCCATCAGGATGCCTTTTTGGACCAGAGAGACTCCCTAGTGAGTCTGCATCTGCAAGGCAACTCGCTTCGTACTCTTCCTCGACATCTCTTCATAAACCTACACAAGCTCCAAGAGTTAGATCTCTCAAGCAACTTTCTAGCCTTCACCATCCAAAACGGCACCTTTTACGAGGAGCTCCAGAATGTTGTGATTCTCAATCTTCTCTACAACTATGAACCCCTGAAAACCTTTCCCGAATTGAATCTGTCACCGTACATAGAGAAGATGGCGTCTCTCAGAGAGTTGTACCTGAGTGGGTTTTTCTTCAAGAAGCTGTCAAACCGCAGCATTGCACCTTTGGTCAAACTTCCAAGACTTGAGGTCTTAGATTTACGCATGAACTTCATCTGCGACATTAGCATTGACGGTCTTAGCCAGCTGAGGACATTAAGAAGAGTAGATCTTTCCCAGAACATGCTCGCCTTTAGTTCGTGCTTTTCAACATGCACTACTGAAGCAGAACACCAAATCCCTGACAGACATGGCAATGAACAGTTCAACCTCCAAATGCAAGAACTCCCCATTCTGAATGCAGAAACACAAGGCTCAAATCCAGACTACTGTTCGTTTTATTTCTCCATGTGGCATTTCAAAAGACAAATCTGCTCTAAAAGCTTATATTTTGACCTGTCTCAGAACAACATCCCATGGCTGAACGCAAGCACTTTTAGAGGCATGGACAGAGTGGCATGCGTAGATCTGTCCTACAACTACATCAGTCAAACTTTAAACGGCCACCAATTCTCACATCTGAGCAAACTATCTTACCTTAATATGGCGTACAACCGTATTGACCTGTATTCCGACAAGGCCTTTCAGGAGGTCAGTGGCACCCTAAAGGCTCTTGACCTCAGCAATAACGAGTTCCACTTTATAATGAAGGGAATGGGGCATCAGTTCACGTTCCTCACGCACATGTCGTCTCTTATAATACTAAGTCTAGCAAACAATCACATCGGTCTCCGGATCTCAAACATCCTCACCAGCGCTTCTCTGAAGTATCTCATTTTCTCTGGGAATCGTTTGGACATATTGTGGGACTCTTGGCGTAATCAATACATAAACCTCTTTCAGGGACTCACCAACCTTACGCACTTGGACATCTCTGAAAATCAGCTCAAATCTCTCTCCCCAGAGGTAATCGTGAACTTGCCTTTGAGTCTCCAAGTTCTCCGAGTCGACTTCAACATGTTGACGTATTTCCCGTGGGCAAACATCTCAGTTCTCCAGCAACTCTGCTACCTCAATCTGAGTTCAAACATGCTTTCGTACTTGCCCAATATTAACTTTGAGCTCCGTCTCACAGGACTGGATTTAAGTCACAACCGACTGGTTGCAATTCCAAAGGTATTCCTTAGTCAGGCAGCAAACCTTAAAAACCTCAATCTCAACAACAACCAACTCAAGATTCTTGACGTCCAGGCTCTCCCCTTGCCATTCCACAAGGGTTGTACTTTCATTCCCGGTGGGCAGCATAAAAACAGGTCCTCCTGCAAACTTGTCCTACATGCCAATCCTTTTACTTGCAGTTGTGTTATTTCAGGATTTGCCAAATTTCTTAGAGAAACCGATTTGGATGTGCCTCATCTCACTACACAGGTTCACTGTGGTTTCCCGGAGTCATTAGCCGGCGTGAATGTCCTCTCGGTGGATCTTCGCTCATGCCAGGAGATATTCGGAGGAGTCGCCTTCCTCTGTACTTCACTATTGACACTAGCAGCAACTTGCGTTCCTCTCCTGAAGCATCTCTACGGCTGGGATTTGTGGTATTTAATCCAGATTCTGTGGACTGGACATCGGGGACACACTCCAGCTAATGGCAACCCCACGGACAACCAGTATGATGCATTTGTGGTCTTCGATACCAGTAATAAGGCAGTCAGGGATTGGATCTACAAGGAGATGCTTGTGAGATTGGAGAACCGGGGAAGATGGCGCTTTCAGCTTTGCCTAGAAGAGCGTGACTGGATTCCTGGAGTCTCGTGCATTGAGAATCTGCACAAGTCCGTTTACAGCAGCAGAAAGACAGTGTTTGTGTTGACCAGCCCTGGGGGTTATTCTGACGCAAGTGGAATAGTACGTCAAGCCTTCCTTTTGGTGCAGCAGAGACTTCTGGATGAGAAGGTGGACGTCGCTGTTCTGGTTTTGCTGGATTTTCTCTTCCCCAAATTCAAGTACCTTCAGATGAGAAAGCGACTCTGCAAGAAGTCAGTTCTGTCCTGGCCCAGAAACCCCCGAGTGCAGCCGCTCTTCTGGAATGACCTGCGCGTCGCTCTCGTTTCTGACAATGTTAGAGCCTACAACAAGAACGTCACGGAGAGCTTCTTCTGAAAACAGGGCCAGGAGCgtaa
>TCONS_00071878
GTTATTATAAAAGATGCTACTCTTtctaaagtgcaatttaattaattagggtaattaggcaagttattgtataacagtggtttgttctgcagacaatcgagagaaaaaaatcttttaatattGACCACAgcatctttaaaataatttttattccagccaaactaaaataaataagaaaaaaagaaaaagggggaaaaataaataacttttttctagaaaaaataaaataaaatagcaaatgcTATGGTGAAAatgtctctgttaaacatcactataatatttaaaaaatgtatctcaAAGGTCTCATATTTTCCCCTTTAATTCCCCCAATATCAGTATGACAGTGGGCACTAGTGTGAGCTACAACTAAAATGCTAAACCATGCACGAAGAGAGGAATAAATCTAAagcaaaagttgaaaaaaaaactcaactgaCTTTGGTTTATTGGAACGTCAGTCTTTTATTTTCAGTAGCGATAACCAGAAATAGCTAATAGGACTCCCTGTTTCATCACATGCTTCACCACTTCTGAACATCTGTTCCTCGATCTGTTTGCCTGATAGACTGACTTTCACTTCCATCTAATGTTCACTACGGTAATATGAATATATCGCCTTAGCTTTACTTGGTTTCTTTGCTTCCCCTTATAAATGTAAGACACACTGCTGCATGGACATGTCAGAGTTGGATTGCAAACGTTTgGCCATGTTTGGACCAATGGTGTCCTTGATTCTGCTTCTGAATCAGTTCCAACTCTTCGCAGCTTCACATCCTCAGTTTTATCCGTGTGAAAGTCACTTCACCAAAGACGGACACATAAATGTGGACTGCCAGCACAGACGGCTCTCTAAAGTCCCCAGGTTCACTTCTCCCTCAGTTATATCACTCAACCTGAATAACAACCATATACACCGCATTAAAGGGGATGCATTTTCTGGTCTACCCAATCTCAAGTATCTCAGCCTGATGTGGAACTGTATATCAGACCGTCTTAAGGAGGCAAGATGGCCGTTATGCAGTGTGAATATTGACCCGGATGCATTTGTTGGACTGAAAAACCTCACTTCCCTTCAGTTAGCTGGGAACAGCTTGAAGATGATTCCTCCTCTGCCAAAGCAGCTTGAAGTCCTGGGACTGGAAttcaacaatatttttaatatcgTCAAACCTTTAGGCACACCACAACTAAAGCAACTGCTGCTAAGCAAGAACTGTTTCTACGCAAACCCATGCCACCAGCCTTACTTTATCAACTCAAGTGTGTTTCAGGATCTTCCTGAGCTTTTGAACCTCACCCTTAGTTACAACAACTTGACTGCCATTCCCTCGTATCTTCCAGGTTCACTAGAAAGTCTAGACTTGCGAGAGAATACAATTGATCACATCAATAAAGAGTCCTTTGCAAATCTCAGAAATCTGCGACATCTCAACCTGGGGTGGAACTGCCAAAGGTGCGACCACGCTTCTGATCCCTGCTTCCCATGCCCAAACAACCAGTCTCTGGATCTCCATCAGGATGCCTTTTTGGACCAGAGAGACTCCCTAGTGAGTCTGCATCTGCAAGGCAACTCGCTTCGTACTCTTCCTCGACATCTCTTCATAAACCTACACAAGCTCCAAGAGTTAGATCTCTCAAGCAACTTTCTAGCCTTCACCATCCAAAACGGCACCTTTTACGAGGAGCTCCAGAATGTTGTGATTCTCAATCTTCTCTACAACTATGAACCCCTGAAAACCTTTCCCGAATTGAATCTGTCACCGTACATAGAGAAGATGGCGTCTCTCAGAGAGTTGTACCTGAGTGGGTTTTTCTTCAAGAAGCTGTCAAACCGCAGCATTGCACCTTTGGTCAAACTTCCAAGACTTGAGGTCTTAGATTTACGCATGAACTTCATCTGCGACATTAGCATTGACGGTCTTAGCCAGCTGAGGACATTAAGAAGAGTAGATCTTTCCCAGAACATGCTCGCCTTTAGTTCGTGCTTTTCAACATGCACTACTGAAGCAGAACACCAAATCCCTGACAGACATGGCAATGAACAGTTCAACCTCCAAATGCAAGAACTCCCCATTCTGAATGCAGAAACACAAGGCTCAAATCCAGACTACTGTTCGTTTTATTTCTCCATGTGGCATTTCAAAAGACAAATCTGCTCTAAAAGCTTATATTTTGACCTGTCTCAGAACAACATCCCATGGCTGAACGCAAGCACTTTTAGAGGCATGGACAGAGTGGCATGCGTAGATCTGTCCTACAACTACATCAGTCAAACTTTAAACGGCCACCAATTCTCACATCTGAGCAAACTATCTTACCTTAATATGGCGTACAACCGTATTGACCTGTATTCCGACAAGGCCTTTCAGGAGGTCAGTGGCACCCTAAAGGCTCTTGACCTCAGCAATAACGAGTTCCACTTTATAATGAAGGGAATGGGGCATCAGTTCACGTTCCTCACGCACATGTCGTCTCTTATAATACTAAGTCTAGCAAACAATCACATCGGTCTCCGGATCTCAAACATCCTCACCAGCGCTTCTCTGAAGTATCTCATTTTCTCTGGGAATCGTTTGGACATATTGTGGGACTCTTGGCGTAATCAATACATAAACCTCTTTCAGGGACTCACCAACCTTACGCACTTGGACATCTCTGAAAATCAGCTCAAATCTCTCTCCCCAGAGGTAATCGTGAACTTGCCTTTGAGTCTCCAAGTTCTCCGAGTCGACTTCAACATGTTGACGTATTTCCCGTGGGCAAACATCTCAGTTCTCCAGCAACTCTGCTACCTCAATCTGAGTTCAAACATGCTTTCGTACTTGCCCAATATTAACTTTGAGCTCCGTCTCACAGGACTGGATTTAAGTCACAACCGACTGGTTGCAATTCCAAAGGTATTCCTTAGTCAGGCAGCAAACCTTAAAAACCTCAATCTCAACAACAACCAACTCAAGATTCTTGACGTCCAGGCTCTCCCCTTGCCATTCCACAAGGGTTGTACTTTCATTCCCGGTGGGCAGCATAAAAACAGGTCCTCCTGCAAACTTGTCCTACATGCCAATCCTTTTACTTGCAGTTGTGTTATTTCAGGATTTGCCAAATTTCTTAGAGAAACCGATTTGGATGTGCCTCATCTCACTACACAGGTTCACTGTGGTTTCCCGGAGTCATTAGCCGGCGTGAATGTCCTCTCGGTGGATCTTCGCTCATGCCAGGAGATATTCGGAGGAGTCGCCTTCCTCTGTACTTCACTATTGACACTAGCAGCAACTTGCGTTCCTCTCCTGAAGCATCTCTACGGCTGGGATTTGTGGTATTTAATCCAGATTCTGTGGACTGGACATCGGGGACACACTCCAGCTAATGGCAACCCCACGGACAACCAGTATGATGCATTTGTGGTCTTCGATACCAGTAATAAGGCAGTCAGGGATTGGATCTACAAGGAGATGCTTGTGAGATTGGAGAACCGGGGAAGATGGCGCTTTCAGCTTTGCCTAGAAGAGCGTGACTGGATTCCTGGAGTCTCGTGCATTGAGAATCTGCACAAGTCCGTTTACAGCAGCAGAAAGACAGTGTTTGTGTTGACCAGCCCTGGGGGTTATTCTGACGCAAGTGGAATAGTACGTCAAGCCTTCCTTTTGGTGCAGCAGAGACTTCTGGATGAGAAGGTGGACGTCGCTGTTCTGGTTTTGCTGGATTTTCTCTTCCCCAAATTCAAGTACCTTCAGATGAGAAAGCGACTCTGCAAGAAGTCAGTTCTGTCCTGGCCCAGAAACCCCCGAGTGCAGCCGCTCTTCTGGAATGACCTGCGCGTCGCTCTCGTTTCTGACAATGTTAGAGCCTACAACAAGAACGTCACGGAGAGCTTCTTCTGA

Function

symbol description
tlr9 Predicted to enable pattern recognition receptor activity. Acts upstream of or within antibacterial humoral response and toll-like receptor signaling pathway. Located in endoplasmic reticulum. Is expressed in blood; heart; liver; muscle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including allergic bronchopulmonary aspergillosis; cystic fibrosis; glomerulonephritis (multiple); hepatitis B; and lung disease (multiple). Orthologous to human TLR9 (toll like receptor 9).

GO:

id name namespace
GO:0034162 toll-like receptor 9 signaling pathway biological_process
GO:0045087 innate immune response biological_process
GO:0007249 I-kappaB kinase/NF-kappaB signaling biological_process
GO:0006955 immune response biological_process
GO:0032640 tumor necrosis factor production biological_process
GO:0002376 immune system process biological_process
GO:0050729 positive regulation of inflammatory response biological_process
GO:0032755 positive regulation of interleukin-6 production biological_process
GO:0051607 defense response to virus biological_process
GO:0051092 positive regulation of NF-kappaB transcription factor activity biological_process
GO:0019731 antibacterial humoral response biological_process
GO:0002755 MyD88-dependent toll-like receptor signaling pathway biological_process
GO:0002224 toll-like receptor signaling pathway biological_process
GO:0007165 signal transduction biological_process
GO:0002237 response to molecule of bacterial origin biological_process
GO:0005783 endoplasmic reticulum cellular_component
GO:0005886 plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0004888 transmembrane signaling receptor activity molecular_function
GO:0038187 pattern recognition receptor activity molecular_function

KEGG:

id description
ko04620 Toll-like receptor signaling pathway
ko05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
ko05162 Measles
ko05168 Herpes simplex virus 1 infection
ko05132 Salmonella infection
ko05152 Tuberculosis
ko05144 Malaria
ko05142 Chagas disease
ko05143 African trypanosomiasis
ko04054 Pattern recognition receptors
ko04090 CD molecules

ZFIN:

id description
ZDB-GENE-040219-10 Predicted to enable pattern recognition receptor activity. Acts upstream of or within antibacterial humoral response and toll-like receptor signaling pathway. Located in endoplasmic reticulum. Is expressed in blood; heart; liver; muscle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including allergic bronchopulmonary aspergillosis; cystic fibrosis; glomerulonephritis (multiple); hepatitis B; and lung disease (multiple). Orthologous to human TLR9 (toll like receptor 9).

Ensembl:

ensembl_id ENSDARG00000044490

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00071877 False 3292 mRNA 0.46 1 53730368 53733659
TCONS_00071878 True 3881 mRNA 0.44 2 53730388 53735399

Neighbor

gene id symbol gene type direction distance location
XLOC_036819 wnt5a coding downstream 49715 53670395 ~ 53680653 (-)
XLOC_036818 lrtm1 coding downstream 81074 53639625 ~ 53649294 (-)
XLOC_036817 parapinopsina coding downstream 182223 53544094 ~ 53548145 (-)
XLOC_036816 selenok coding downstream 187944 53537103 ~ 53542424 (-)
XLOC_036815 actr8 coding downstream 195065 53517998 ~ 53535303 (-)
XLOC_036821 apeh coding upstream 12526 53747925 ~ 53773539 (-)
XLOC_036822 NA coding upstream 46082 53781481 ~ 53781852 (-)
XLOC_036823 BSN coding upstream 58623 53794022 ~ 53803429 (-)
XLOC_036824 CABZ01090219.1 coding upstream 105903 53841302 ~ 53851585 (-)
XLOC_036825 mib2 coding upstream 127346 53862745 ~ 53896982 (-)
XLOC_036813 NA non-coding downstream 262665 53464218 ~ 53467703 (-)
XLOC_036812 CU914536.1 non-coding downstream 373472 53356779 ~ 53356896 (-)
XLOC_036807 NA non-coding downstream 794898 52933059 ~ 52935470 (-)
XLOC_036805 NA non-coding downstream 847592 52877822 ~ 52882776 (-)
XLOC_036801 NA non-coding downstream 1098884 52627507 ~ 52631484 (-)
XLOC_036829 NA non-coding upstream 326298 54061697 ~ 54068296 (-)
XLOC_036830 NA non-coding upstream 334762 54070161 ~ 54075099 (-)
XLOC_036832 NA non-coding upstream 376630 54112029 ~ 54113768 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000050_01039500_01042679 TLR9 coding CI01000050 null 1039500 ~ 1042799 (+)