XLOC_000419 (hhip)


Basic Information

Item Value
gene id XLOC_000419
gene name hhip
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 35790082 ~ 35835863 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00000716
ACATGTGAGTGCACTGAGGAGCATGCAACACAACTTAGTGAACTTTTGATCACAACTGTCAACTTCTGTGCACATCGGGATTTAACTTTTGGTCAAGGAGACGTACTGCGATTTCTACATATAATCtgattacttttctttttttctatataattttttttcttttaaaaatcgcATTAATATGCAATAtcatgtttttttccattttaataacGTCTTAACCAGAccttgtattaatttattatcgtaatttctttcttctttttttgtaaacACCTATTTAGCGAGTAGTTGCTTTATCTAAATTGGTTATTCTGTAAGAACTTTCAGGACGCGTGGGGCTGTCATTCAGCAGTCCTGTTTATTTCTGAGCAGCCGCGTGTTTCGCGTTTGCTTTCATCCCTGCAAAAATGAAGCATTTGAAATTTGTGCTCTTGTTAGCCATCGCGGCCAATTTTTGGGAATGTGGTGATGCGAAATTTGGCGAGAAAGGAGAATTAAGTCCAAGGAGGAGGAGATGTTACGATGGAAGTCTGCCGAGACGCCTGAAGAAGAAGGAGAGAAAACTGTCACTCGAGGGAAGCGGTGGAGGGGAGGTTTGTCACAGGCTCTATCCTCGCGTGTCCTGCTGTCCGTCCAGGAGGGCTCCGTATCAGATACTGCATCGGAAAGATGCTCGGACTTTCTCGACTAATAACACGGAGTGTTCTAGACTGCTGGAGGAGATTAAGTGTGCCCATTGCTCACCAAATGCTCAGATGCTGTTCCATTCACCTAAACTTGAAAAAGCACCACATAGAGAACAAGACCTACCCCGCTTATGCCATGACTACTGCCAAGAGTTCTACTACACTTGCCGTGGACACGTACCAGAACTGTTCCAAGCCGACGTGGATGAGTTCTGCCAGTActatggaaggatggatggaggcCTGTGCTTTCCAGATTTTCACCGAAAGCAATTGCGGAGAGATTCCAACTACCTGTTAGATGAAAAAACCGAAGCGATTAACAGaaaacacaaacacaactgcTACTGCGCTCAGGAGATCCATAGTGGTCTTCAACAACCTGTTGGCGTGGTGCATTGTGGAGATGGATCGCAGCGGCTTTTTATATTGGAGAGGGAAGGCTTTGTGTGGATCCTCACACATGACATGGAACTCCTAAAAGAGCCTTTTCTGGACATTCATAAGCTGGTACAAAGTGGTTTAAAGGGGGGAGATGAAAGGGGCTTGCTAAGCCTTGCATTCCACCCCAATTATAAGAAAAATGGCAAGCTCTACGTCTCCTATACGACCAACCAGGAGCGATGGACTATTGGACCACACGACCACATTCTTCGTGTAGTGGAGTACACAGTGTCCAGaaaaaatccAAACCAGGTGGACACAAGGACTCCTCGGGTTTTAATGGAAGTTGCGGAACTTCACCGAAAGCATCTGGGAGGCCAGCTCCTCTTTGGGCCTGATGGGCTTCTGCACATCTTTTTAGGAGATGGCATGATCACTTTGGACAATATGGAGGAGATGGATGGTCTAAGTGATTTCACAGGTTCTGTTCTTCGGGTGGATGTGGACACAGAATGTTGTAGTACTCCCTACTCCATACCCAGAAACAATCCCTATTTTAACAGCACAAATCAACCCCCCGAAATTTTTGCCCATGGTCTGCATGACCCAGGGAGGTGTGCAGTAGATAAGCTCCGCATGGACACCAATGGGAGTCTGCTGATCCTGTGCACAGATACAGTTGGCAAAAATACGACAACAGGCAGGATCCTACAGGTCATCAAAGGGAAAGATTACGAAAACGAGCCATCTATGTTTGACTTGGGGTCAAGCGGAGGTACCACCCCTGTTGGTGGATTTATCTACAGAGGATGTCAGTCAAGAAGACTTTACGGAAGTTATGTATTTGGAGACAAAAATGGGAACTTTAGAATTCTCCAGAGGCCTTTAGAAGACCGATTGTGGCAAGAGAAGCCTCTTTGTCTTGGTACTAGCAGTTCCTGTGGTTCCTCGCTGGTAGGCCACATCCTGGGGTTTGGCGAAGATGAATTAGGTGAGGTCTACATCCTTGTCTCCAGCAAGAGCACAGCCAAACAGTCGCATGGAAAGATCTACAAGTTGGTGGACCCCAAAAGACCACAAGTTCCAAAGGAGTGCAGAAGACCAGTAGAAGATCCAGAGATGCTAAGCACTGCTTGTTCACGTGAATGCAAGAACGGCCACTGTACACCAACTGGCAAGTGCTGCTGCAATGCAGGCTGGGAGGGCCCCTTCTGCTTACGAGCCAAGTGTGAACTGGCTTGTCGCAATGGCGGGGTCTGTGTGGAGCCCAACAAGTGTCTCTGCAAGGAAGGTTTTTCTGGCAACCAGTGCAGTAAAGGAGAGCGAGGGACAAAAGGGGACGGTGAGAAAGACAGCATCCTGGAGCACATCATTGACATGACGACTTACCTGCTGGACCTCActagttatattgtttaaaaagcaaGGCAGGAAGCTGACTCGCTCTTCACCATTTGGCAATGTTACGAAGGCCGTTCAGAGTTTGCCTTCAGTACACCATCCCCAAATCTCCAACTGCCCCTCACCTGATCCTCCTCTCCCACCACTGTTCTGTATTATGAGCCACAGGCTTTGATATCTCCATGCTCCCCTACACCATCTGCactcccacaaacacacacataaaacaataACATGGTGTCCAAAGGAACCTCAACACACTTAGCCAAAGGGGGTCGCATGTTGGAGATGAACACAGTGCTCCTCTGTTTGGTGTGTAAGGTCAAGTGTCCCCGCAAGAGGTCTCAAAGCACTGGAAGCCCCACCTCGGATGTTCAGACCGACCCTAACAATTGGGATATTAGGGTGTCAACAACGCCTCAAGTGGACAGTCTATCAAACTGAACTGCACCATAAAGAAACTCACTGCCACAGATTGTTCTAAGAACGGAGAGGAAGGAGCTGTCAGTACAGCAGCAAAACCGTACAACAGACTTGCTCTGTGTAGAACTGGAGAATCATATTGATGGGACTTGATGCCAGTTTACTTGCAGTTTAAAACCGGATTTGCTAAAAAAGGTCATCTATTTCTTGATACAATTGTTGAAAGGATTAATGAGGATCCTGCAAAACTGAATATTGGTTGATTCCTGTTGATGTTTCATTTAGAAGAAAAAGTCAAGTGAAATCAATCTTTAAAGAATGTTTGGACAGTCACTTTGATTAACTTAATACACGAGTTAAAGACGACTGGTTTGCAGGGAGAAACTACCCTCGAGAGGAAAAATTGCAGTATCAGTTAACCTATTTCCTGTAGTTTTTCATGGCCATGCACGCTGCTTTCATTGCAAATTGTATCctttatcatattttaaattgttCATCTATCATCTTTTGTGTGATGTAAAGCACAGAAGCTTGTTTTTATAAATGGAAAACCCTCGTGAGGCAATTTTAGCTACTACTATCGTTTTTGTCTTACATTGACTTCACAGATTATGTTTTAAGTTCTCCATTTAACACCAAACCCTATTCAGTTTTGTCATATACAAAAGGGAACATGACTGGTGACTGGTGTACATTTCATATAGTACTCTACAAAGTACTGCTTAGATTTGCCATTGTTTTAATAGagggtttattttttttaaggaataataTATGGGAGAGGAGCAGTTTTGCATTAAGCCTGtaaattcatttatgtattttacttATAGATATACAGGTTTGACATCTATAAAAATCTTAACTTAAAGCTATAACAGTGTTCTTTTACTTTCAAGAGTGctttgactgaaaaaaaaaacacaaccataGATCTTTCCTTCCAACAATGTGACATTTCTATAAAACAAAGTTCCAGCTATAATTTGAGACTATCATTTTAGTCAGCCAGCTCTTAAACGAATAGGTGATGTTAAATATGCTTTGCGTCATTAAGACTCCATAGCATCCCTTTACTTTCAGATGTTGTTGGTTAAGCTCTCTTAAATGAGCTCTCTTCTACAAAATGCACTATAAATCAAGCAGAAATCATCCCATACTTCAGAAAATTACCTCATCGACAGCGGTTCTATCACTGAATAACTGATAAGACTACATCTAGACAACAATTGGACCCCTGTTCAACTTTATACTCACTTGTTGTCAATGAGGTCCTTATTTACATGTTTCATTGAGCCCTTTTTGATGTGATTCTTGTCATTGAAGGTTTACATCCCCCTCTAAAATCAGACATATTCAGTATGATCAATAACAATCCCCGTGCGTTTATCATGTTCTGTTCAGTGCATGTACGGAATCCATGCTGTAAATCTACTCTGTTATTTTAGCACTTAATGTGAAACCTGCATTGGAGCTGCTGGGAAGGTGTGATGTGAATAGAGTAACCCTGTTTCCTTTATTATTTAAGTAGTTATGCCTTAAAGTTATTTAAGTTGTCTACAATGTTTTTACTGTTTATGTGAAGAAATATGGTCATTTATTGTAAATAACTAGGTTTATCTTGGGTTCTTCTCAGAAATATCAATATGTTTATTAAAGTGTATAGCATGTTTGA
>TCONS_00000717
ACACAGTAGAAATGACTCTTGCACTCAAAACAGCAATGCGCAGCAAACGCGCGAGTCTGGAGACGCTTTTTTCTAAAGTTGTACTTGTTTAACTTGACACGGCGTCTTAAAAAACGTGGCACGAGACGCGTATAAACACGGAGACCGTCCGCAATGTCCGCCGCGCTAATGTTTACACAGGAAAACGATTGAAAACAACTCGGAGTGAGACTTTCTCGACTAATAACACGGAGTGTTCTAGACTGCTGGAGGAGATTAAGTGTGCCCATTGCTCACCAAATGCTCAGATGCTGTTCCATTCACCTAAACTTGAAAAAGCACCACATAGAGAACAAGACCTACCCCGCTTATGCCATGACTACTGCCAAGAGTTCTACTACACTTGCCGTGGACACGTACCAGAACTGTTCCAAGCCGACGTGGATGAGTTCTGCCAGTActatggaaggatggatggaggcCTGTGCTTTCCAGATTTTCACCGAAAGCAATTGCGGAGAGATTCCAACTACCTGTTAGATGAAAAAACCGAAGCGATTAACAGaaaacacaaacacaactgcTACTGCGCTCAGGAGATCCATAGTGGTCTTCAACAACCTGTTGGCGTGGTGCATTGTGGAGATGGATCGCAGCGGCTTTTTATATTGGAGAGGGAAGGCTTTGTGTGGATCCTCACACATGACATGGAACTCCTAAAAGAGCCTTTTCTGGACATTCATAAGCTGGTA

Function

symbol description
hhip Predicted to enable catalytic activity. Acts upstream of or within fin development; negative regulation of muscle organ development; and negative regulation of smoothened signaling pathway. Is intrinsic component of plasma membrane. Is expressed in several structures, including axis; mesoderm; muscle cell; nervous system; and pharyngeal arch. Human ortholog(s) of this gene implicated in chronic obstructive pulmonary disease. Orthologous to human HHIP (hedgehog interacting protein).

GO:

id name namespace
GO:0045879 negative regulation of smoothened signaling pathway biological_process
GO:0048635 negative regulation of muscle organ development biological_process
GO:0009968 negative regulation of signal transduction biological_process
GO:0033333 fin development biological_process
GO:0031226 intrinsic component of plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0003824 catalytic activity molecular_function

KEGG:

id description
ko04340 Hedgehog signaling pathway
ko04024 cAMP signaling pathway
ko05200 Pathways in cancer
ko05217 Basal cell carcinoma

ZFIN:

id description
ZDB-GENE-030131-4827 Predicted to enable catalytic activity. Acts upstream of or within fin development; negative regulation of muscle organ development; and negative regulation of smoothened signaling pathway. Is intrinsic component of plasma membrane. Is expressed in several structures, including axis; mesoderm; muscle cell; nervous system; and pharyngeal arch. Human ortholog(s) of this gene implicated in chronic obstructive pulmonary disease. Orthologous to human HHIP (hedgehog interacting protein).

Ensembl:

ensembl_id ENSDARG00000060397

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00000716 False 4575 mRNA 0.42 13 35790082 35835863
TCONS_00000717 True 731 processed_transcript 0.47 4 35790892 35803084

Neighbor

gene id symbol gene type direction distance location
XLOC_000418 gab1 coding upstream 180423 35494837 ~ 35609659 (+)
XLOC_000417 usp38 coding upstream 299077 35473219 ~ 35491005 (+)
XLOC_000416 sc:d189 coding upstream 555382 35194454 ~ 35234700 (+)
XLOC_000415 NA coding upstream 696570 35034294 ~ 35093512 (+)
XLOC_000414 NA coding upstream 929025 34857368 ~ 34861057 (+)
XLOC_000420 si:ch211-194g2.4 coding downstream 26687 35862550 ~ 35867943 (+)
XLOC_000421 NA coding downstream 60529 35896392 ~ 35898437 (+)
XLOC_000422 BX276105.1 coding downstream 113406 35949269 ~ 35954313 (+)
XLOC_000423 mmaa coding downstream 120572 35956435 ~ 35970259 (+)
XLOC_000424 zgc:152968 coding downstream 149950 35985813 ~ 36002774 (+)
XLOC_000408 NA non-coding upstream 1335635 34450659 ~ 34454447 (+)
XLOC_000407 CR848003.1 non-coding upstream 1389728 34400240 ~ 34400354 (+)
XLOC_000403 dre-mir-734 non-coding upstream 1667110 34122880 ~ 34122972 (+)
XLOC_000425 BX324156.1 non-coding downstream 318398 36154261 ~ 36154377 (+)
XLOC_000431 NA non-coding downstream 1130137 36966000 ~ 36966282 (+)
XLOC_000432 FO704615.1 non-coding downstream 1287779 37123642 ~ 37123772 (+)
XLOC_000436 NA non-coding downstream 1755395 37591258 ~ 37638367 (+)

Expression


Co-expression Network