XLOC_000418 (gab1)


Basic Information

Item Value
gene id XLOC_000418
gene name gab1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 35494837 ~ 35609659 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00000713
AGGAGCCGTGGGGAGTGAAACTGGAGGGAAGGTCGACGATCGGGGAAGATTTCCACTTCCAAAGGCACTTCTGTGCTAATGCGACCATAATGTTTTGGAAAAACAAGGAAAAACTGTACATATTTTCAAGGaaactgttttgttttactttgaaaTAAGGTAATCAAGCAGAGCTTTCACTACGCCGAACTTGGCGAGTATCAGTCGCTGCCTCGTTGCATATCAGCTCGGAAAAAACGAAAACAGCGTTTTATTTACACGGACAAAGTGTGTCAACTAAAAGGGGACTCAACTACAGACGGATACATGTGTGTTTAAATAAACTGTGCTTAATATATTCCCTTCGGCAGAGGAGAGGACTTCATCCAGAAGAGTTTGCGAGAGCCGCGTCGCTGTCGGGAAGCTCTTCCCGTGTGAACGTGCTGGAAACCAGGAGTGACGGCTGAAACACGAAACTTAAAACCCGTGTTTTCCTCAAAGCCTTTAAGAAAATGAGCGGAGGAGATGTGGTTTACTCGGGGTGGCTCCGAAAGTCTCCACCTGAAAAAAAGTTACGGCGTTATGCATGGAAgaagcgatggtttgttctgcgcAGTGGGAGGCTGTCTGGAGACCCAGACGTGCTGGAGTATTACAAGAATGACCATGCCAAGAAGCCCATCCGCGTTATCGATCTGAACCTGTGCGAGCAGGTGGACGCCGGTCTCTCCTTCAACAAGAAGGACCTGGAGCACAGCTTCATCTTTGACATCAAGACTATCGACAGGATCTTTTACCTGGTGGCAGAAACTGAAGAAGATATGAACAAGTGGGTGCGCAACATCTGTGAAATCTGTGGCTTCAACCCCACCGATACAGAAGACTCTGCAAAGGTCTCTCATCATGTAAATGTGCCAGGCGGTCTGGTGGTGGATATGGCCCCTAGTGGAGGGCTGGGCGGAGCTTTAGGGGCGTCTGCATTAGCCAACCTGCCTCCTCCCTACCAGCCCGTCAGCATCAGACAGCTGGGATCATCCTCCAGTCTAGATGAGCCTCAGGACTACCTTTGGCTGCTCAACTGTGAGAGCAAAAAACCTGAGCCTAACAGGGCTCATGGCGACTGCTCCAAGTCTACCTCCTCTGAACCTGACTGTAATGACAACCTTCCTTCCCACTACACACCCACCTCCTCCACCTCCAAAAACGCCCCGGTCAATGGTTTCTTTTCCACCCAACATCCCACTGGGCTCTACGATTCTCCTCCTTTGCGCGGGCAGTCATTGTCGGCCGACTCACAGGGCCTGTACCACCTGCCCCGAAGTTACTCTCAGGACACTGTGCTGCTGCCGAAGTCGGCGACCTCCCCTCCCATTCCTGACGGTGAACCTGGTGAACTCTATGTCTTTAACACACCTGGTCGGAAACCCTCATTAGAGGCCCATTTGCGGAACTTGTCAGTTAGCTATGATATTCCACCTACACCTGGCAGCAATTCCACCTACCAGGTTCCCCGAACAGCAGGAGTGGAGGCTGTTTCAGGGTCCACAGAGGTAATTCCACCACCACGTCCACCAAAGCCTTCAGTGAGTGGGGGATCAGTCCCACCTGAGCGATCGCCTACAGACACTTATGTGGTACCGCGGTCAGTGTCTGAGACTGATACGAATTACTGTGTTCCGACAAGTGCAGGAGGCAACAAAGCACTCAGAAGCAACACCATTGGTACGGTGGATTCTTCACGTCTGCGTAAAGATTACGGATCTCAAGACTGCTATGATATACCCCGGCCCTTCCCTTCAGAAAAAAGTTGCTCGTTTGATTTTAATGAAAGTTTCAACAACTATTTTAAAAATAAAGGCATGGTGCCAGTAGGAGGTGTTTCTACAGAGGAAATGGATGAAAACTATGTTCCCATGAGCGTCCACTCTTTGTCACATCAGCGCTCCGGCAGCCTATCAGAACCTATACAGGAGCCCAACTACGTCCCCATGACACCAGGCACAGTGGAGTTCTCTTCCCTTGGAAAACAGGTGCCCCCTCCAGCCCACATGGGCTTCAGGTCCAGTCCCAAGACACCACCCCGTAGACCGATTCCTATATCTGAATGCCAACCTCCACCCATAGACCGCAACCTCAAACCTGACCGTAAAGGTCAGAGCCCTAAAATAAACAGAGCAGTCGGTCTTGAGCGGACCGACTCCCAAACCATAGGTGAATTCTCAAGACGGCGTAAGGTTAAGCCAGCCCCTTTGGAAATCAAGCCTGTATCTGAATGGGAGGAGTATACAGCACCGGTTCGATCGCCCGTCACCAGGTCCTTCACGAGGGACCCTTCTAGGTTTACTGTGGCCCCCAGACCGTCCTCGGGGCAAAGCACTGCCTCCAGCAGCGACTCGGACGAGTGTGATGAGAATTATGTAACCATGCAGGCTAATATGTCTTCAGATGAACCaAACAAGTTAGGAGCACCAATGAATGCTGATGGAGGTGGCAGTCCCATGGTGAAACCCAAAGGAGACAAGCAGGTGGAGTACCTGGACCTCGACTTGGACCCTGGGAAATCAACTCCACCTCGAAAGAAGAAGAATAACGGGACTGGTATTTCTGCATCAGATGAGCGTGTAGACTATGTGCTGGTGGATCAGCAGCGAACGCAAGCACTGAAAAGCACCCGGGAGGCCTGGAGTGATGGACGGCAGTCGACAGAGGACACCCCCACCAAAGGGGCCAAATGACATCCATCTCTTCTGGTAGGTCAGGACTCGTGGGAGACCCAGGAAGGGAGGACACCGCACAAGCTCTGAACCTCCTATCTGGCCCTCCACCTTTGATTTTAGATACAGCTGTGTGACAGCGCCTAGGTCACAGCTCCCAGATCAGCTAGTTTACACTGCTTCCTGCTAGACGACAGTACCCACGCAGGGGAGAGCTGGTCCCAGGGATCCTCACCAATAAGCTGACAGACTCAAAAGTATGGACTGCACACTGCACAGGGGCTGAAGAACTTGCCAAGCCACTTCGGCTGAAAGCCCAGTGAAAATGATGCTAAACAGAAGCAGGTATTATTCCTACACACTGCCCACCACCCATCCACATTTTTTCGTTTGGATATCATTTTCTCCCATCATGGTATCAAAGCACATTATTCCAATGGCTTGGGGTACATCAGGTCTGTCCTCAAGTAATGTTCCATGTTCACAAAACTGCCAAGTCGAGGACGTTTTAGAAGCctaaaatgttcatttgtgtATAGTTTCTTGATAATCTGAAACCAGTAGACATCTAGGTTTCAGAATGTtccattagttttttttcttttggcctCAAGTGTAATTTGGTAGTGCAATCAAAAGGTGTTGAGTTTGCTTGAACTGCAAATCTACTTAAGGTGACAGAGttagtttgttaaaaaaaaagaaagaaaaaagatttttgttggCGTTTAAGACAGCAGGCAGACTGTATAAAGTGTTATGTACATGAATAAAAGTGTCCTTTATTTGTATCTTAATATCCAGTGTGAGTTAAGGCTAAGATGTGGATTCTGCAGGATAGAAGTCTACACGGTCTGAGATGGTATCAGAAACTATGAAATGTTATCGGTGGAATCAGGAACTGTGATCGTTTTTATTAGAGAAGAGAattctctgttgttgttgttgttgttttgtgtgttttatgttcTTATTTTGGctcctttctcttttttttcaaagCAAGGTATCAATTTACAGAAGCGCTGAGGTCAGGTACTCACTGAAAGGTTGAACAGATTTCATGTTTGAATTTTATTCTGCAGCTTTAGATGACATCTCAAGCGTTGCAGTTTGTATGTTCTCGtagaaaccttatgaaattgcTCATGATGCAAGATATTATGACAAAGGCTTTGTGCTGTATGAGATCATGCCTTCGTGGAAAGGAGGAAAAGTCGGTCAAGTAGTTTCAGGTATTTTCTTTTGTCTCTGTGTTGACTGGTCTATCAATGCGTTTTATTGCCACttcaataatttatttcaaatagAGTCCACGGCTCTTGAAGACTAATTGCCTTACcgttgcaactttttttttttttaaatgatgtaaatatgATTCATTCACTGATTTTTAGCTCATGTCAGAACACATCTATTGAGAATACATCAGCATAGAAGTCTACTGtgtgtatgtaaaataaaaataaaaaagctctaCTAACTACCGTTCTTAAGCCAAGAAGACAGCTGCGGTGTATCAGAACATTGGTGGCTTCTGCTGTATATATCCATACAGGCTCTTCAAGCATGTCTTTAGATTCAAAGCTGTGCCTATGTTGTTTCTGTCTACTCAAAtctgtttttcttctttcttttcttcgtTGAGTTCTCAGACCCTGATGCTTTATATCTTTTTTAATGAATCTGAAAGAAATGTACATTTGAAAATAAACTCAATAAAATGATACTTCAGGAGATTACTGCTGACATTGCAA
>TCONS_00000714
CTTCTGTGCTAATGCGACCATAATGTTTTGGAAAAACAAGGAAAAACTGTACATATTTTCAAGGaaactgttttgttttactttgaaaTAAGGTAATCAAGCAGAGCTTTCACTACGCCGAACTTGGCGAGTATCAGTCGCTGCCTCGTTGCATATCAGCTCGGAAAAAACGAAAACAGCGTTTTATTTACACGGACAAAGTGTGTCAACTAAAAGGGGACTCAACTACAGACGGATACATGTGTGTTTAAATAAACTGTGCTTAATATATTCCCTTCGGCAGAGGAGAGGACTTCATCCAGAAGAGTTTGCGAGAGCCGCGTCGCTGTCGGGAAGCTCTTCCCGTGTGAACGTGCTGGAAACCAGGAGTGACGGCTGAAACACGAAACTTAAAACCCGTGTTTTCCTCAAAGCCTTTAAGAAAATGAGCGGAGGAGATGTGGTTTACTCGGGGTGGCTCCGAAAGTCTCCACCTGAAAAAAAGTTACGGCGTTATCTGCTCTTCTGACGTGTCGTTCTCATGAGGTGCCTGACAGCAGCATGGCGACCATTTCCTGCGCTGCTGCTGTTCTACCCCAGCTGATGCTTCCCAGATGGCTATAGAGAGCtctttctcgctctctctttctctattctTTATTTGGAACAAAGCCCAGTTATTGGTCTGAGTGCATTAAGAGGAGGTgttggagagagagagtgaaatgaGTAGGCTGGAAGACCTGCGCTGGAAAACAGTCGCGTGGGATTGAAGAATCAGTTTTGGCTGTTGTAGTGACACTCCAGAATGACTGACATAATAATCCAAATTTACTCTAATAGAAAACACGTGTGTCCTGTAAGTGAGCATTACATCATAGTTTTTAGGGGCTTTTAGATATGCAACTTGGAAGTGACCAAACACAAATTCTTGGTCACAACCAAGAAACCCGCCCCCAAAAAATGTTGCCTTTCTGACTTTTTGACATGAAAACCTCTTCTAGTTTACTGCAGTAGATTTGAGCTGAGGAATGTTTTCATAAGTAAAGGACTACAATCTTGGTTACTACATCAGCACCATCTGGACCTATGGACTTTAAATGCACAAATAGCAATTTGAGTTTGTGCTCCATtctaatttatttcttttattaatatatcatttgttttgtcatgtttcgcTGGTGATTCTGAGTTctgcaatatttatattttaatcaatttgCTGCT
>TCONS_00000715
GCTGAAACACGAAACTTAAAACCCGTGTTTTCCTCAAAGCCTTTAAGAAAATGAGCGGAGGAGATGTGGTTTACTCGGGGTGGCTCCGAAAGTCTCCACCTGAAAAAAAGTTACGGCGTTATGCATGGAAgaagcgatggtttgttctgcgcAGTGGGAGGCTGTCTGGAGACCCAGACGTGCTGGAGTATTACAAGAATGACCATGCCAAGAAGCCCATCCGCGTTATCGATCTGAACCTGTGCGAGCAGGTGGACGCCGGTCTCTCCTTCAACAAGAAGGACCTGGAGCACAGCTTCATCTTTGACATCAAGACTATCGACAGGATCTTTTACCTGGTGGCAGAAACTGAAGAAGATATGAACAAGTGGGTGCGCAACATCTGTGAAATCTGTGGCTTCAACCCCACCGATACAGAAGACTCTGCAAAGGTCTCTCATCATGTAAATGTGCCAGGCGGTCTGGTGGTGGATATGGCCCCTAGTGGAGGGCTGGGCGGAGCTTTAGGGGCGTCTGCATTAGCCAACCTGCCTCCTCCCTACCAGCCCGTCAGCATCAGACAGCTGGGATCATCCTCCAGTCTAGATGAGCCTCAGGACTACCTTTGGCTGCTCAACTGTGAGAGCAAAAAACCTGAGCCTAACAGGGCTCATGGCGACTGCTCCAAGTCTACCTCCTCTGAACCTGACTGTAATGACAACCTTCCTTCCCACTACACACCCACCTCCTCCACCTCCAAAAACGCCCCGGTCAATGGTTTCTTTTCCACCCAACATCCCACTGGGCTCTACGATTCTCCTCCTTTGCGCGGGCAGTCATTGTCGGCCGACTCACAGGGCCTGTACCACCTGCCCCGAAGTTACTCTCAGGACACTGTGCTGCTGCCGAAGTCGGCGACCTCCCCTCCCATTCCTGACGGTGAACCTGGTGAACTCTATGTCTTTAACACACCTGGTCGGAAACCCTCATTAGAGGCCCATTTGCGGAACTTGTCAGTTAGCTATGATATTCCACCTACACCTGGCAGCAATTCCACCTACCAGGTTCCCCGAACAGCAGGAGTGGAGGCTGTTTCAGGGTCCACAGAGGTAATTCCACCACCACGTCCACCAAAGCCTTCAGTGAGTGGGGGATCAGTCCCACCTGAGCGATCGCCTACAGACACTTATGTGGTACCGCGGTCAGTGTCTGAGACTGATACGAATTACTGTGTTCCGACAAGTGCAGGAGGCAACAAAGCACTCAGAAGCAACACCATTGGTACGGTGGATTCTTCACGTCTGCGTAAAGATTACGGATCTCAAGACTGCTATGATATACCCCGGCCCTTCCCTTCAGAAAAAAGTTGCTCGTTTGATTTTAATGAAAGTTTCAACAACTATTTTAAAAATAAAGGCATGGTGCCAGTAGGAGGTGTTTCTACAGAGGAAATGGATGAAAACTATGTTCCCATGAGCGTCCACTCTTTGTCACATCAGCGCTCCGGCAGCCTATCAGAACCTATACAGGAGCCCAACTACGTCCCCATGACACCAGGCACAGTGGAGTTCTCTTCCCTTGGAAAACAGGTGCCCCCTCCAGCCCACATGGGCTTCAGGTCCAGTCCCAAGACACCACCCCGTAGACCGATTCCTATATCTGAATGCCAACCTCCACCCATAGACCGCAACCTCAAACCTGACCGTAAAGTTAAGCCAGCCCCTTTGGAAATCAAGCCTGTATCTGAATGGGAGGAGTATACAGCACCGGTTCGATCGCCCGTCACCAGGTCCTTCACGAGGGACCCTTCTAGGTTTACTGTGGCCCCCAGACCGTCCTCGGGGCAAAGCACTGCCTCCAGCAGCGACTCGGACGAGTGTGATGAGAATTATGTAACCATGCAGGCTAATATGTCTTCAGATGAACCaAACAAGTTAGGAGCACCAATGAATGCTGATGGAGGTGGCAGTCCCATGGTGAAACCCAAAGGAGACAAGCAGGTGGAGTACCTGGACCTCGACTTGGACCCTGGGAAATCAACTCCACCTCGAAAGAAGAAGAATAACGGGACTGGTATTTCTGCATCAGATGAGCGTGTAGACTATGTGCTGGTGGATCAGCAGCGAACGCAAGCACTGAAAAGCACCCGGGAGGCCTGGAGTGATGGACGGCAGTCGACAGAGGACACCCCCACCAAAGGGGCCAAATGACATCCATCTCTTCTG

Function

symbol description
gab1 Acts upstream of or within epiboly. Is expressed in brain and inner ear. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 26. Orthologous to human GAB1 (GRB2 associated binding protein 1).

GO:

id name namespace
GO:0090504 epiboly biological_process
GO:0005575 cellular_component cellular_component

KEGG:

id description
ko04012 ErbB signaling pathway
ko04014 Ras signaling pathway
ko04072 Phospholipase D signaling pathway
ko04722 Neurotrophin signaling pathway
ko05205 Proteoglycans in cancer
ko05225 Hepatocellular carcinoma
ko05226 Gastric cancer
ko05211 Renal cell carcinoma
ko05100 Bacterial invasion of epithelial cells
ko01521 EGFR tyrosine kinase inhibitor resistance
ko04990 Domain-containing proteins not elsewhere classified

ZFIN:

id description
ZDB-GENE-040426-2674 Acts upstream of or within epiboly. Is expressed in brain and inner ear. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 26. Orthologous to human GAB1 (GRB2 associated binding protein 1).

Ensembl:

ensembl_id ENSDARG00000037018

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00000713 False 4453 mRNA 0.46 12 35494837 35609659
TCONS_00000714 False 1209 processed_transcript 0.42 3 35494904 35515273
TCONS_00000715 True 2204 mRNA 0.52 10 35495368 35607935

Neighbor

gene id symbol gene type direction distance location
XLOC_000417 usp38 coding upstream 3832 35473219 ~ 35491005 (+)
XLOC_000416 sc:d189 coding upstream 260137 35194454 ~ 35234700 (+)
XLOC_000415 NA coding upstream 401325 35034294 ~ 35093512 (+)
XLOC_000414 NA coding upstream 633780 34857368 ~ 34861057 (+)
XLOC_000413 zgc:172122 coding upstream 687778 34763539 ~ 34807059 (+)
XLOC_000419 hhip coding downstream 180423 35790082 ~ 35835863 (+)
XLOC_000420 si:ch211-194g2.4 coding downstream 252891 35862550 ~ 35867943 (+)
XLOC_000421 NA coding downstream 286733 35896392 ~ 35898437 (+)
XLOC_000422 BX276105.1 coding downstream 339610 35949269 ~ 35954313 (+)
XLOC_000423 mmaa coding downstream 346776 35956435 ~ 35970259 (+)
XLOC_000408 NA non-coding upstream 1040390 34450659 ~ 34454447 (+)
XLOC_000407 CR848003.1 non-coding upstream 1094483 34400240 ~ 34400354 (+)
XLOC_000403 dre-mir-734 non-coding upstream 1371865 34122880 ~ 34122972 (+)
XLOC_000425 BX324156.1 non-coding downstream 544602 36154261 ~ 36154377 (+)
XLOC_000431 NA non-coding downstream 1356341 36966000 ~ 36966282 (+)
XLOC_000432 FO704615.1 non-coding downstream 1513983 37123642 ~ 37123772 (+)
XLOC_000436 NA non-coding downstream 1981599 37591258 ~ 37638367 (+)

Expression


Co-expression Network