XLOC_005176 (egr2b)


Basic Information

Item Value
gene id XLOC_005176
gene name egr2b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007123.7
NCBI id CM002896.2
chromosome length 49182954
location 8483838 ~ 8504278 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00009990
ATTCAGCAACACAGAGCCGTCAGATGGCATCACAGTGAACGCTAAACTCACTGATCACTGACAGCTTTCCACATGTAACGCTTCGTGCGCGCGTTCGCACAGACACAACACATTCTGTGAACATCCGAGCGAGTGCTTCTTAGGACTTCACGATGACAGCTAAAACTTTGGAGAAAGCCCCTGTGAGTCTCGGTGGCTTTGTGCACCCTCTTGCCGATAGCATCTATTCGGTGGACGAGCTTGCCACAACACTGCCAGCCTCTGTGACTATATATAACGATTTAGGAGGACATTACGAGCAGATAAACGCAGGAGATGGCCTGATTAACGGGGATATGAGCACGGAGAAGCGCGCCCTCGACTTAGCCTACTCCAGCAGCTTCGCGCAACCAGCTGGCCCTCGCAACCAAACTTTTACCTACATGGGAAAGTTTTCCATCGACTCCCAGTACCCGGGAAACTGGAACCCAGAGGGCGTGATCAACATCGTGAGCGCGGGGATCCTGGGCATGACCCAGCCATCCTCAGCATCCTCGTCACCTGCATCCTCAGTCTCCCCCAGCCACTTCTCCAGCACTCTCAGCTGCACCATGGCGCAGAACCAAGCAGACATGGAGCACATCTACTCCCCCCCGCCGCCCTACTCTGGATGCGGAGAGGTCTATCAAGACCCGTCTGCGTTCCTTTCCACCTCCACCTGTCCCATCTCATATCCTCCGCCATCCTACTCCTCTCCAAAGCCAAACGCCGACTCTGGGTTGTTCCCTATAATCCCGGACTACGCCGGCTTTTTCCAACCTCCGTGCCAGAGGGACATGCAGTCGATGCCCGACCGCAAACCGTTCTCCTGCCCGCTGGACTCTTTCAAATTACCGCCTCCTCTAACCCCCCTGAACACTATCAGGAACTTCACGCTAGGGGGACCAGTGCCTGACGGACCCCGGCTACCCACAGCTTACACTCCGCAGAATTTGCCCCTCAGGCCAATCCTGCGTCCAAGGAAATACCCCAACAGACCCAGCAAGACGCCCGTGCACGAGCGGCCCTACCCCTGTCCGGCGGAGGGCTGCGACAGGCGCTTCTCGCGCTCGGACGAACTTACCAGACACATCCGCATCCACACCGGCCACAAACCCTTCCAGTGTCGGATATGCATGAGGAACTTTAGTCGCAGCGACCACCTGACGACCCACATTCGCACGCACACCGGCGAAAAGCCGTTCGCCTGCGACTTTTGCGGGAGAAAGTTCGCGAGGAGCGACGAAAGAAAGAGACACACCAAAATCCACCTGCGACAAAAAGAGCGAAAGTCCTCCTCGTCGTCCACAGGAGTGTCCAGCTCAGAGCGCGGCGTCGCCACGAGCATCTGCTCGTCCAGTTCAAACCAGTGAACTTTCAACTGGACCGTGCAATATCCAACACTATGTAGGCAATACAATAATGCACCGTTCGTGTTTTATTAAAACTGGGTGGACTGATGAGGTGAAATCAAACCACAGTGCCAAACATGGACACTTTCTTTGCGCACACTTTTAGTAAAGGTGAtgcaaagttgtttttaaatgCCTCAGTCGCATGCTGACTGACCCAAACGCACTTTGTTTGAATATTTAGgccaattaatttaataataataataaaataaccttAGATAGCACGTGGGAGAATTGTGTCTTAGATTTTAAAAGTTGGAAAGTGGAGTGCTTacgtttttttaaaagttaatttaaacaaactaaacttTCAAGGAGGTGTCTAACATCACTATTTTCTCCCATCGTCGTGCCTTTCGTCCGTTCATCTTGTACAGAGAGGCGTGGATGAAATTGTACATTAGCCTTTAATATGAAAGTTTTGGAAGATATATTTTTGTACAAACTGTTTTGTGTCGTGCTTAAACATGGATGTATATAGCTGAACTATATCGTTTGTTCTGTGGTTGTTTGGACtgttatacatgtatttgttatGAAGTGACTAACGCGGGTCAATAATGTCCTACTTTGTCAACttgaaaataataaacaacacaTGAATTGTGAA
>TCONS_00009991
AGTTTGCAGATCATcccaggagtgtgtgtgtgtgtgtgtgtgtgtggagctgctGTGGAGCGGTTGGAGCTCTTTGGAGGAACCCACTCATATGATGGCAAGTCACAAAGAGCCACTCTTCATGCCGCACTGATAATATGGCCTGATTAACGGGGATATGAGCACGGAGAAGCGCGCCCTCGACTTAGCCTACTCCAGCAGCTTCGCGCAACCAGCTGGCCCTCGCAACCAAACTTTTACCTACATGGGAAAGTTTTCCATCGACTCCCAGTACCCGGGAAACTGGAACCCAGAGGGCGTGATCAACATCGTGAGCGCGGGGATCCTGGGCATGACCCAGCCATCCTCAGCATCCTCGTCACCTGCATCCTCAGTCTCCCCCAGCCACTTCTCCAGCACTCTCAGCTGCACCATGGCGCAGAACCAAGCAGACATGGAGCACATCTACTCCCCCCCGCCGCCCTACTCTGGATGCGGAGAGGTCTATCAAGACCCGTCTGCGTTCCTTTCCACCTCCACCTGTCCCATCTCATATCCTCCGCCATCCTACTCCTCTCCAAAGCCAAACGCCGACTCTGGGTTGTTCCCTATAATCCCGGACTACGCCGGCTTTTTCCAACCTCCGTGCCAGAGGGACATGCAGTCGATGCCCGACCGCAAACCGTTCTCCTGCCCGCTGGACTCTTTCAAATTACCGCCTCCTCTAACCCCCCTGAACACTATCAGGAACTTCACGCTAGGGGGACCAGTGCCTGACGGACCCCGGCTACCCACAGCTTACACTCCGCAGAATTTGCCCCTCAGGCCAATCCTGCGTCCAAGGAAATACCCCAACAGACCCAGCAAGACGCCC

Function

symbol description
egr2b Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within embryonic organ development and nervous system development. Predicted to be located in nucleus. Is expressed in several structures, including nervous system; neural crest; neural keel; neural plate; and neural rod. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 1D; Charcot-Marie-Tooth disease type 3; Charcot-Marie-Tooth disease type 4E; and motor peripheral neuropathy. Orthologous to human EGR2 (early growth response 2).

GO:

id name namespace
GO:0006357 regulation of transcription by RNA polymerase II biological_process
GO:0021575 hindbrain morphogenesis biological_process
GO:0048568 embryonic organ development biological_process
GO:0021654 rhombomere boundary formation biological_process
GO:0048932 myelination of posterior lateral line nerve axons biological_process
GO:0005634 nucleus cellular_component
GO:0046872 metal ion binding molecular_function
GO:0003676 nucleic acid binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding molecular_function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-980526-283 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within embryonic organ development and nervous system development. Predicted to be located in nucleus. Is expressed in several structures, including nervous system; neural crest; neural keel; neural plate; and neural rod. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 1D; Charcot-Marie-Tooth disease type 3; Charcot-Marie-Tooth disease type 4E; and motor peripheral neuropathy. Orthologous to human EGR2 (early growth response 2).

Ensembl:

ensembl_id ENSDARG00000042826

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00009990 False 2043 mRNA 0.50 2 8483838 8486330
TCONS_00009991 True 853 mRNA 0.57 2 8484850 8504278

Neighbor

gene id symbol gene type direction distance location
XLOC_005175 NA coding downstream 3130 8477459 ~ 8480708 (-)
XLOC_005174 CR354434.1 coding downstream 39817 8443904 ~ 8444021 (-)
XLOC_005173 NA coding downstream 89193 8388330 ~ 8394645 (-)
XLOC_005170 NA coding downstream 410575 8003509 ~ 8073263 (-)
XLOC_005177 CR932364.1 coding upstream 5362 8509640 ~ 8511185 (-)
XLOC_005178 NA coding upstream 69655 8573933 ~ 8575025 (-)
XLOC_005179 jmjd1cb coding upstream 77597 8581875 ~ 8817999 (-)
XLOC_005180 CR354554.1 coding upstream 355915 8860193 ~ 8860307 (-)
XLOC_005181 cyp26a1 coding upstream 450483 8954761 ~ 8958353 (-)
XLOC_005171 NA non-coding downstream 437365 8039984 ~ 8046473 (-)
XLOC_005184 CR854953.1 non-coding upstream 612774 9117052 ~ 9117178 (-)
XLOC_005185 NA non-coding upstream 723108 9227386 ~ 9237794 (-)
XLOC_005187 CR457459.1 non-coding upstream 841086 9345364 ~ 9345485 (-)

Expression


Co-expression Network