XLOC_005194 (heatr1)


Basic Information

Item Value
gene id XLOC_005194
gene name heatr1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007123.7
NCBI id CM002896.2
chromosome length 49182954
location 9619909 ~ 9700605 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00010020
GGCACACTTGCACACACGTGGATACTGGTGCGGTAATAACTACAACCAAAGATGACATCGTTAGCGCATCAGCTGAAGCGGCTGGCCTTGCCGCAGAATGACTCGAGTCTGCTCGGCCGGAAAGAGGTGGTCTCTGTGCTCTTTGACCCTAAAGATGCAGCCAGTATGGACCGCAGCACCTTCCATGCACTTGGCTGCACGGGACTGGAGGAGCTGATGGGTATTGATGCAGCGTTCAGTGAGTTTCAGGAGACTCTGTTCAGTCAAGGATCTTTGACTTTAGAGCGCAGCGTTCAGTCCAAAGAGGTCAACAAGAAACTGGACAAGAGCATTTCTCTCTTCCTCACTCGACTGTCACCTTACTTTCTGCTCAAGCCTGCTCTGAAATGCATTGAATGGCTTTTACACAGATTTCACATTCATCTGTACAACCAGGACAGTCTGATTGCTTGTGTTTTACCGTATCATGAGACTAAAGTGTTTGTACGAGTGATCCAGCTGTTCAAGATTGAAGATCCAACCCACAAATGGCACTGGCTCCATGGAATCCAGAAACCTGGTGTTCCCCTGGCCCGAGGAACCCTGCTCACACACTGCTATAAGGATTTAGGCTTCATGGATTTCGTTTGCTCTATGGTCACAAATTCAGTAAAGGCGTACTCTGAACTGACCCGGGATGGGAACTGTCCGCAGCTGCGTGTGATTTTCTCTTTCTATGCATCGACTATTGTTTCAGCACTTGATGCAGTGGAGAAGATCACTAACTCTATTATTGCCAAACTGCTTCCCTTTGTACAACTGGGGCTGAAATCTAATCTTTCGGACTACACGGCTGCCACTTACATGATCGTGTGTCAGATGGCAGTGAAGGTGGTAATGGAGGCCCAGCTGGTGGACTCTCTGAGCGTTCAATTGAGCAGGTCTCTAGGCCGAACACCACAGCTCATCAGAGAAGGCTTGAGCTGCATTATCATCCTGCTCCAAAACCAGAAAAAAGGAGTGATTGGTCAAAAGACATATGGTTACCTGTGTGCTGTCCCTACCCTGGTGTCTACCCTTCAGAGCATATCAACTGTGCATGACATCAGTCCTCTACTGAGTTACCTGCTGCCTCATCTCATACACTCTGTGATGACCCAGAATGATGAGCAACAGAATGAAGGTTTGTCAGACAGTACTGGACTATTGCAGTCAGTATTTCAAAACCTTCAACTTTCCAGCAACCTGGAGAACACTGCAGCTAAGCTGCTGCTTGAAGAGTATGTTGTCTGCGGCAATGAGCTTCCCTCAGATGGGATTTCAGCTCTTAATCAGAGAATTCAGCCTACAGTACGACTGTTTGAATCCAGGTATCCATGTGCACTGGATATGGCATTGGAAAATCATGTCAAAAATGTGTCATCCGATAATGAAAAAAACCTGCTTCATCAGTTCATCTCTCTCACTCTGAGCTGTGGGAAATATCAGATTCTGCCGGAGTCCGAGACCTCTCTGATGCTCAGCCTCAATCACCCTCTTCCCTCTGTGAGAAACATGGCCGTAGACTACCTGAAAGAGATCCTCAACTCAGAACATAATAGCTTTGATGAGGCGTTTCTCAAAGATGCTTTGCTGGAAAGAATAAAAGACGATTCTCCAGAAGTTGTGCTGTCTGCGCTTAAAGCCTTGCAGCATCACATGGGCCTAATGGATGTAGAGGACACCGTTTCCAGTTTGATTTCACTTCTTCATCGCATCAAACCATCAGCcgattgGTGTCCAGTGCTAAAAGAGGCTGTGCGCGTTCTTGATGACCCACGCATTATTGAGGGTAACCCAGATCTTAAGGCTTACATTAGTTGGGAGCTTTTACCCTTCCTGGTGATGACGAGAGCTGCACCTGAATGTGTGGAGCTGCAGATGACGTCTGCCATTACTGAAACCACTCTGATCTCCCAGCATCCTCTGACCCAGGGCTGGGCCAAAGTGCTGAAGGCTGTTCTGGCTAAAACCTCTGAGTCGGATCTGCTTGGTGTGGCGAACGAAATGCTCACAACAACTCTGATCAAGAACTTGGCTAACATGGATCACGCAACCAAACGCAACACTCTGGAGAACGTGTGTGATATCCTGAGCCGTCAGGGCAGTAGTGTGCGGGACAGAGCAGCGTTTGTGGTGTTTAGTTCTGCTCTGCTTCAGAGTCTGCAGTCCATGACGGAGAGCCAGCACCTCCACACCGCACAGAGTGTGTATAAACTACTGGAGCCTTTACTGCTGCAGGCATACACCATCCAGCCTGAACAGGTGTCTGATCAGCCCGCAGATGAGTGTCTGCCAGTCTGTGTAGCTTTGGGTGAGTTTCTGCAGAAAATCAGCTGTGGTTTGAGTGCAGAGCAAGAACAAGGCCTTCTTCTGCTTTCTCTTCTGCGGCTTTTCATCACGACCCTCAAATGTCCAGATTCTACATTTAAAGGTGAGCCATGGTGGAACCCAGAGAAAATGGAGACTACTACATGCTGTTACCTGCGTCTCCTCTGTCGTCTGTTTGATGTGGTGATATCAGGGGCCAGTCAGGGGCCCTTGGCTCCCTGCTTCAGGAGCCTAATGCAGCCTCTATTACAGGTGCACCTGAATGAGCCGATGGTCCTGTTTAAGTTTCTGTCTCTGTTATGGGGCTACAACAGCAATTTAGGCGATCAGTTGGATTGTCGAGTCAGTGCCATTCTTCAGACTCAGGCTCTTTATGTGGGAAAGGCTTTTCTGTCCAGCCAGCCTGTAAAAACCCTCAACCTGCTGGCGTCAGATTCCTCACCAGTGGTGCCGTCTCTGCTGGTGTGTGTATGTTCAGGCGTGTGTGAAGTTCGTAGAGCTGCCATCGCTGTGCTCCAGTGTCTCTCTGGGCTTGTTTCTTCACCGTATCATCCGCTTGTGGAGAAACTCCTCAAATCATCAGAGGAGATCATCGCTGACTCCTCATATCTTACCCAAGCATTGTCCAAGTTCTACGAGGAGGCCGTTTCACGGAAAGATAAGAATAAAAAGTTGGCATCAGTTGAGCAGCTCCTTCAGTGTTTACAGTCTCCCTTCTGTCCTTCCTACACCTCCAAAACACTTCTGCGGGCTCTTCAGGATGTTCACGGAGAGCCTGTTTTGTCTGTTCTTCTTCCTGCTGTGGAGCGCCTTCTTGAACAGTGTGCTCCAGACTCTTGCACCTTCCTGCCAGACGAGGCTCTTCTTCTGCAGCTCTTGTTGAGCAAGTTCAGTGAGATGTCGGCACCTTTACTGGTCAAAGATCCTCGATGCCTTGAGGTCTTCATTAGAGCACTCCACACCTCAGCCAGGCCATACCCTACTATCCCCAGCTTCCAGATTACTGCCCTGGAGCAGATTACCAAGCCGTTCTTCACTGCTATTGGAGATGAAAAGATTCAACAGAAGATTCTTTCGATTTTGTTTGACCTGCTTGTTGGGAATAAAAGCCCTGCCTGCGCCCAAAGTATCAACAGTGTCTTTAAAACGATTGCAGTGGATTGCGAGCTTGTGGCCAATGAGCTGATTCCTGCCGATAAACAAAGAGTTACTGCAACAGTTCAACAAACGCGCAGAAGTAAAATGAGAAAAACACAAGACACATCTGGGGCAGTGCCAGAGGAGAGTGTTGTTTCTTGGCCAAGGGTGACGCTAATTTTAGAGCTGCTTCAACACAAGAAGAAACTTAAGAGGGCTCAGTATCTAGTGCCCGCTCTGTTTAATTTGCTCTCAAGGTGTCTGGAACCTGCTGCTGCTGAACAGGAGAATATAGAGTACACAAAACAGCTCATCCTCATCTGCCTGTTGAATGTCTGTCAGAAACTGTCTCCAGAGGGAGGGCCAATCAGCAAAGaTGTGCTGGAGGAGGATAAGTTTAATATGGAGCTGGTCGTTCAGTGTGTCAGGGTGTCAGAAATGCCCCAAACTCACCATCATGCTCTGCTTCTGCTCGGGGCTCTGGCCGGCATCTTCCCTGAGAAGGTTCTTCACAACATCATGCCCATCTTCACTTTCATGGGAGCCAACATCATGCGCTTGGATGATACTTACAGCTTCCAAGTCATCAACAAGACTGTTCAGGCAGTCATCCCTGCTCTGATtaagGCCCACGAGGGAGGAAGTTCTCAGTCTGAGGGTCATATGGAGACTGTGGTAGCCCAGATCATACATGTGTTTGTTGATGCTCTTCCTCATGTGCCCGAGCACAGACGGTTACCCATCCTCAGCCAGCTGATGAGCACACTGGGCCCGTCccgcttcctctgggtgctgatGCTGCTTCTGTTCAAGCAGCATGTCACACAAACATCTGCTGGTGCGACGGGGGCTGAAAAGGAGGCTGTTGTGGAGAGAGATCAAGACTTCTGGATTTTGGTGTGTTGTGAGTTTGAGGTGAAGGAGCAGCTGACTTCCCTTATCAAAATCCTGCAGTATCTCATGACTCTGCCACAAGATAGAGAAGAAGCACCAGAGAAAAAGAAACCCCGTGGAAGAAGTGCCGTGAAGAAAGATGAAACAGTCTCTGATCTGATATTCAGTGTGGAGACTCACAGTGGCAAAGACCTCCGCCATTTTAAATTCATCTCCATCTCCTTCATGGCTCAGCTGCTGGCCTCTGACGGATTCGTTGGGAAGGTGGCTGACTGTGAAGACATTACAGAAAGTACCTTACAGGCTCTTCAGCAAGATTTGTTGGTGGAGGTTCTGCGCTACATTCAGGCAGTTGCTCGATGTGTCGAGGATAATGCAGATAAGCCAACAGCTAAGTTCTGGAGAGCCCTCCTAAGCAAGTCCTATGACACCCTGGACAAGGTCAATGCCCTTCTACCAATGGATACGTTCATTACGGTAATGAGAGGCTTGATGGGTAATCAGTTGGCATCAGTAAGAAGGAAGGCCATGGAGTTACTCAATAACAAACTACAACAGAGGACGAAGTGGCTGAAGGAACAGATCACTGCTCTTCTTGAGCTCATTGGCACTCTTCTGAGCATCGTGGGTCGCAGTCATCGTCAGGTCACGGCCCAGGAAGAAGAAGAGCTGGCCATCAATCGACAGACGGCCCTTTATAGCCTCAAGCTTCTGTGCCGAAATTTCGGCTCTGATCACAAGGAGGAGTTTGTACCAGTGCTGAATAAAGCGGTGGAGCTGGTTGCTGATAAAGACGAGGAGAAGAATGTCATGGGAAGTGCTCTGCTGTGTGTAGCGGAAGTTACCAGCACTCTGAAAGCGCTTGCTATACCACAGTTACACAGGCTGATGCCCGCTGTGCTGGACACTCTTAAGGAAAGGAAGGACCTGCTAAATAATGAAATCTACCTACTGAGCGCCGTCACAGCTCTACAGCGGGCATCTGAGACTCTGCCACACTTCATCAGCCCATACCTGCTGGACACCATCTTACAGGTCACCCGTTTAACTCTGCTGGCCAGGCGACTGACATCTTGCCCTCAGTTATCTGTACGCCTGGCCTCTCTCAGCTCCACTCTCGCCACAAAACTTCCTCCCAGGGTCCTCATTCCTACCATCACTAAATGCTACTGCAGCATGGTGGATGCTCAGCAGAATCGTCTCAGTCCTCTGATGAACATCCTGAAGGAACATATCAGCCACATGGACAAAGACCAACTCAATAACCACCAATCAGAGCTCACTTCCTTCTTCCTGTCTGCGCTTGATTTCCGTGCTCAGCATTGCCAGGGCGATCTGAAGAAGACTGCTGAGATCGAAGGCTGCGTGATCGACTGTCTGCTAGTGATGATTATGAAACTTTCAGAAGTCACTTTCAGGCCTCTTTTCTTCAAGTTGTTTGACTGGTCAAAGATTGACGGTGCTTCTAAAGATCGCCTGTTGACCTTCTACAGACTTGCAGATCGTATCGCAGACAAACTCAAAGGACTGTTTGTGTTGTTTGCTGGCCAGCTGGTCAAACCCTTTTCCGATCTGCTGCATCAGCTCAACACTTCCCACACAGACAAAGCCTTCTTTGACTCCGAGGATGAGAGTGATGATGATTCAGATGAGGAGGCTGATGATAATGTGACAAAGAGCAGCCTTTTGCTACAGTATGTGTTGGACTGCCTTCACAAGATCTTCCTCTATGATACTCAGCACTTCCTCAGTAAGGAAAGAGCTGATGCCCTTTTGTGTCCTCTGGTGGATCAGTTGGAGAACATACTAGGAGGAGAGGAGACCTACAAGAGCCGCATTACCACACACTTGGTGCCTTGCATTGCTCAGTTTGCTGTTGCCATGAGAGACGACTCGCAGTGGAAAGTTCTCAATTATCAGATTCTGCTCAAGACACGACACAGTTCACCAAAGGTTCGTTTCTCTGCGCTTGTCATGTTGCTGGAGTTGGCAGGCAAGCTGAGGGAGAACTACATGGTTCTTCTGCCAGAGACCATCCCATTCCTGGCCGAGCTCATGGAGGATGAATGCGAAGAAGTTGAGCACCAGGTTCAGAAGGTCATTCAAGAAATGGAGACTATCCTCGGTGAACCGCTGCAGAGCTACTTTTAATGGCACCTGAGGCAACTACAGTGTATTTGTTATCCTTACATAACTGATGAGCTGTCATGCTGAAACATACGTCAGTCTGTCCACCATCTTCTCCTGCACATCCGAACATTTGATTGATTGGCAGCTTGACCAGTCATGCCTACCTATGTGTCTATGCATATGTATATGAAGAAAATGACTGGATGCCCCGCCCTTTATATGAAAGCGACGCATGGGATGAGTATATGTgtctgatgtttttaaaaaatgttttatggcaTTGAATGATGTTTTGTAATGCACACTGATGTATTTCTGTGGAAACTGCATATCATAAAAAGATTAATCTGGGGGAAA

Function

symbol description
heatr1 Predicted to enable snoRNA binding activity. Acts upstream of or within maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); negative regulation of apoptotic process; and regulation of RNA stability. Predicted to be located in nucleolus. Predicted to be part of 90S preribosome; small-subunit processome; and t-UTP complex. Is expressed in eye; forebrain; immature eye; midbrain; and midbrain hindbrain boundary. Human ortholog(s) of this gene implicated in pancreatic ductal carcinoma. Orthologous to human HEATR1 (HEAT repeat containing 1).

GO:

id name namespace
GO:0006364 rRNA processing biological_process
GO:0043066 negative regulation of apoptotic process biological_process
GO:0042254 ribosome biogenesis biological_process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biological_process
GO:0043487 regulation of RNA stability biological_process
GO:0045943 positive regulation of transcription by RNA polymerase I biological_process
GO:0030686 90S preribosome cellular_component
GO:0032040 small-subunit processome cellular_component
GO:0034455 t-UTP complex cellular_component
GO:0005634 nucleus cellular_component
GO:0005730 nucleolus cellular_component
GO:0030515 snoRNA binding molecular_function

KEGG:

id description
ko03008 Ribosome biogenesis in eukaryotes
ko03009 Ribosome biogenesis

ZFIN:

id description
ZDB-GENE-030131-6378 Predicted to enable snoRNA binding activity. Acts upstream of or within maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); negative regulation of apoptotic process; and regulation of RNA stability. Predicted to be located in nucleolus. Predicted to be part of 90S preribosome; small-subunit processome; and t-UTP complex. Is expressed in eye; forebrain; immature eye; midbrain; and midbrain hindbrain boundary. Human ortholog(s) of this gene implicated in pancreatic ductal carcinoma. Orthologous to human HEATR1 (HEAT repeat containing 1).

Ensembl:

ensembl_id ENSDARG00000099742

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00010020 True 6867 mRNA 0.48 45 9619909 9700605

Neighbor

gene id symbol gene type direction distance location
XLOC_005193 arg1 coding downstream 2139 9597151 ~ 9617770 (-)
XLOC_005192 nudt13 coding downstream 81331 9519250 ~ 9538578 (-)
XLOC_005191 si:ch211-207i20.3 coding downstream 102928 9510477 ~ 9516981 (-)
XLOC_005190 si:ch211-207i20.2 coding downstream 121849 9482875 ~ 9498060 (-)
XLOC_005189 pgap3 coding downstream 151291 9449665 ~ 9468618 (-)
XLOC_005197 prdm9 coding upstream 80919 9781524 ~ 9796237 (-)
XLOC_005198 ngfrb coding upstream 249336 9949941 ~ 10038870 (-)
XLOC_005199 BX928755.1 coding upstream 360031 10060636 ~ 10063668 (-)
XLOC_005200 NA coding upstream 424055 10124660 ~ 10129902 (-)
XLOC_005201 mpp2b coding upstream 498614 10199219 ~ 10300101 (-)
XLOC_005187 CR457459.1 non-coding downstream 274424 9345364 ~ 9345485 (-)
XLOC_005185 NA non-coding downstream 382115 9227386 ~ 9237794 (-)
XLOC_005184 CR854953.1 non-coding downstream 502731 9117052 ~ 9117178 (-)
XLOC_005180 CR354554.1 non-coding downstream 759602 8860193 ~ 8860307 (-)
XLOC_005178 NA non-coding downstream 1044884 8573933 ~ 8575025 (-)
XLOC_005214 NA non-coding upstream 1068526 10769131 ~ 10772946 (-)
XLOC_005222 BX572641.1 non-coding upstream 2634611 12335216 ~ 12335331 (-)
XLOC_005224 NA non-coding upstream 3402261 13102866 ~ 13106223 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000047_00035357_00069520 HEATR1 coding CI01000047 null 35357 ~ 69917 (+)