| Item | Value |
|---|---|
| gene id | wt1a |
| gene name | wt1,wt1a,LOC108413264,LOC105030317 |
| gene type | coding |
| species | striped catfish (Pangasianodon hypophthalmus) |
| category of species | economic fish |
| Item | Value |
|---|---|
| chromosome id | NC_047601.1 |
| NCBI id | CM018547.1 |
| chromosome length | 30450434 |
| location | 25547089 ~ 25568303 (-) |
| genome version | GENO_Phyp_1.0_2019_striped_catfish_Genome |
| symbol | description |
|---|---|
| wt1a | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within animal organ development. Predicted to be located in cytoplasm and nuclear speck. Is expressed in several structures, including cardiovascular system; gonad primordium; mesoderm; pleuroperitoneal region; and podocyte. Human ortholog(s) of this gene implicated in several diseases, including Denys-Drash syndrome; Frasier syndrome; malignant mesothelioma; nephroblastoma; and nephrotic syndrome type 4. Orthologous to human WT1 (WT1 transcription factor). |
| wt1 | Enables several functions, including C2H2 zinc finger domain binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and double-stranded DNA binding activity. Involved in several processes, including animal organ development; regulation of apoptotic process; and regulation of gene expression. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in cytosol and nuclear speck. Implicated in several diseases, including Denys-Drash syndrome; Frasier syndrome; malignant mesothelioma; nephroblastoma; and nephrotic syndrome type 4. Biomarker of breast cancer; endometrial cancer; nephroblastoma; and ovarian serous carcinoma. |
| description |
|---|
| PREDICTED: Wilms tumor protein isoform X1 |
| id | name | namespace |
|---|---|---|
| GO:0006355 | regulation of transcription, DNA-templated | biological_process |
| GO:0071320 | cellular response to cAMP | biological_process |
| GO:0072149 | glomerular visceral epithelial cell fate commitment | biological_process |
| GO:0071371 | cellular response to gonadotropin stimulus | biological_process |
| GO:0043066 | negative regulation of apoptotic process | biological_process |
| GO:0008285 | negative regulation of cell population proliferation | biological_process |
| GO:0039021 | pronephric glomerulus development | biological_process |
| GO:0039022 | pronephric duct development | biological_process |
| GO:0030325 | adrenal gland development | biological_process |
| GO:0005634 | nucleus | cellular_component |
| GO:0005737 | cytoplasm | cellular_component |
| GO:0046872 | metal ion binding | molecular_function |
| GO:0003676 | nucleic acid binding | molecular_function |
| GO:0003700 | DNA-binding transcription factor activity | molecular_function |
| id | description |
|---|---|
| K09234 | WT1; Wilms tumor protein 1 |
| RNA id | representative | length | rna type | GC content | exon number | start site | end site |
|---|---|---|---|---|---|---|---|
| XM_026946429.2 | True | 3416 | mRNA | 0.45 | 9 | 25547089 | 25568301 |
| XM_026946430.2 | False | 3408 | mRNA | 0.45 | 9 | 25547089 | 25568302 |
| XM_026946432.2 | False | 3333 | mRNA | 0.45 | 8 | 25547089 | 25568302 |
| XM_026946433.2 | False | 3325 | mRNA | 0.45 | 8 | 25547089 | 25568303 |
| gene id | symbol | gene type | direction | distance | location |
|---|---|---|---|---|---|
| pax6a | pax6,pax6a,pax-6,LOC107572247,LOC107589163,LOC107674982,LOC107707493 | coding | downstream | 73019 | 25458823 ~ 25474070 (-) |
| nav2b | LOC108268924 | coding | downstream | 350327 | 25072336 ~ 25196762 (-) |
| exoc3l1 | LOC108269298,LOC108413953 | coding | downstream | 524135 | 25008231 ~ 25022954 (-) |
| prmt7 | prmt7,LOC108413952,LOC102778684,LOC108411915,LOC107573013,LOC107577788,LOC104944886,LOC107683005 | coding | downstream | 543503 | 24991666 ~ 25003586 (-) |
| coq9 | coq9,LOC107382780,LOC107589199,LOC107707431 | coding | downstream | 564750 | 24976356 ~ 24982339 (-) |
| LOC113546502 | ccdc73 | coding | upstream | 14063 | 25582366 ~ 25605123 (-) |
| trnam-cau_20 | NA | coding | upstream | 30138 | 25598441 ~ 25598513 (-) |
| trnam-cau_21 | NA | coding | upstream | 30978 | 25599281 ~ 25599353 (-) |
| trnam-cau_22 | NA | coding | upstream | 32994 | 25601297 ~ 25601369 (-) |
| trnam-cau_23 | NA | coding | upstream | 33925 | 25602228 ~ 25602300 (-) |
| G121482 | NA | non-coding | downstream | 163852 | 25382958 ~ 25383237 (-) |
| G121425 | NA | non-coding | downstream | 311582 | 25232714 ~ 25235507 (-) |
| G121174 | NA | non-coding | downstream | 620840 | 24926040 ~ 24926249 (-) |
| G121172 | NA | non-coding | downstream | 622252 | 24924622 ~ 24924837 (-) |
| G121169 | NA | non-coding | downstream | 624094 | 24922772 ~ 24922995 (-) |
| G121581 | NA | non-coding | upstream | 45670 | 25613973 ~ 25614560 (-) |
| G121582 | NA | non-coding | upstream | 46818 | 25615121 ~ 25615887 (-) |
| G121583 | tcp11l1,LOC107572299 | non-coding | upstream | 47980 | 25616283 ~ 25617258 (-) |
| G121584 | NA | non-coding | upstream | 49430 | 25617733 ~ 25618325 (-) |
| G121572 | tcp11l1 | non-coding | upstream | 52158 | 25620461 ~ 25682477 (-) |
| mapk8ip1a | LOC108268451 | other | downstream | 928974 | 24585356 ~ 24618115 (-) |
| cacna2d4b | cacna2d4,LOC108268693,LOC107574657 | other | downstream | 1430155 | 24079841 ~ 24116934 (-) |
| LOC117597766 | NA | other | downstream | 1735197 | 23811702 ~ 23811892 (-) |
| LOC117597751 | NA | other | downstream | 1736591 | 23808602 ~ 23810498 (-) |
| LOC113528756 | LOC108268501,LOC103028890,LOC108416834,LOC107574299,LOC101068009,LOC107716653,LOC107753697,LOC107661481 | other | downstream | 1979101 | 23563831 ~ 23567988 (-) |
| G121585 | NA | other | upstream | 50309 | 25618612 ~ 25619310 (-) |
| lrrc29 | LOC108268915 | other | upstream | 1658656 | 27226959 ~ 27237260 (-) |
| cep290 | cep290 | other | upstream | 1979043 | 27547346 ~ 27591334 (-) |
| G123154 | NA | other | upstream | 2640810 | 28209113 ~ 28212830 (-) |
| LOC113546677 | NA | other | upstream | 2759957 | 28328260 ~ 28329458 (-) |