serpinc1 (serpinc1)


Basic Information

Item Value
gene id serpinc1
gene name serpinc1
gene type coding
species striped catfish (Pangasianodon hypophthalmus)
category of species economic fish

Chromosome Information

Item Value
chromosome id NC_047605.1
NCBI id CM018551.1
chromosome length 26640196
location 12736065 ~ 12744758 (-)
genome version GENO_Phyp_1.0_2019_striped_catfish_Genome

Sequence

>XM_026930383.2
TCGCACTGAGTAAATTGTTGGCGCTACAGTGCTCTGTGGGACACTGACCTGTTCGCCTGTCTTACATTTACGCTTTACCACTGAGCAGTGTCGCCTGAAATTCTGCTGTCTTAGAACGGATTTAAGATCCTAACAGGTGAGAATGAAGTGGGTGGTGTGTATAGGAGTTTTCTGGATCCTCTCCACCTCCATAGCTCATGCAGCCATTGACATCTGCAGCCTGAAGCCCAAAGATCTGCCCCTGGAGCCGGTGTGTATATACCGCAACCCAGACATCCCCGACAATCAAGAAGATCCGACCAAGATCCCTGAGAAGATCCCTGGATCTACCAACCCTCGAGTGTGGGAGCTGTCCAAAGCCAATGGGCGCTTTGCCCTTTCTCTCTTCAAGCAGCTCTCCAAAGGCAAGTCTGAGGATGCAAACATCTTCATGTCCCCGCTCAGCATCTCAACAGCCTTCGCCATGACGAAACTGGGGGCTTGCAACAGTACACTGGAGCAGATCATGAAAGTGTTCGAGTTTGACACAATAAAGGAAAAGACGTCAGATCAGGTTCACTTTTTCTTCGCCAAGCTGAACTGCCGCCTCTATCGTAAAACACACAACTCTGTGGAACTGGTCTCGGCCAACCGTCTGTTTGGAGAGAAAACGTTCGAGTTCAACGAGAACTATCAGAACATCAGTGAGATGGTGTACGGGGCCAAGCTAATGCCACTCAACTTTAAGGAGAAACCCGAAGCTTCGAGGCAGATAATCAACGAGTGGATTTCTGAGAAGACAAACCATAGAATAAACAACACTTTGCCTGAGGGCTCAATAGACGTAAATAGCATTCTGGTGCTGGTCAATACCATCTACTTTAAGGGTCAATGGAAACATAAATTTAACAGACGTAATAGCATGGAGTCCAAATTCCATATCAGCAAGACGCACAGCTGCCTGGTGCAGATGATGTATCAGGAGAACACATATCACTATGGACACTTCCCAGAGGACAAGGTACAGGTGCTCGAGATGTTCTACAGTGGAGAAGGCATTTCAATGATGATTGTATTACCAGACAAGGACACAAAGCTGGCTGAGGTGGAGGAAAATTTAACCCTTAAGAAACTCAGTGGCTGGTTGAACGACACAAAAACTAAACAAGTGGCAGTGCACTTCCCACGTTTCCGCATAGAGGACAACTTCAGCCTCAAAGAGAAGCTTCACTCTATGGGGCTCCATGATATCTTCAGTGCAGAGGACGCCAGTCTACCAGGCTTGGTGGCGAACAATCAGAATGACCTTTACGTCAGTGATGCCTTCCACAAAGCTTTCCTTGAAGTCAATGAAGAGGGCAGCGAGGCCGCAGCTGCTACTACTCTCCTGTTCGTTGGTCGCTCCCTCAACCCGAACCGCGAGGTGTTCGTAGCCGATCGGCCTTTCCTGCTCTTCATCCGAGAAACCACTATCAACACGCTGATCTTCGCAGGCCGTGTGGCAGATCCCTGCTCAGGCAGATAAGGAGATACACATTCACTCCTTTCCTCATGATGagtgaggagaagagagaggaagattATGATGAAGAGCTCGATGGTGGTGTTATTATTCTCATCCATCAGGGGGTATGATGGTGTTcaatttcattattcattataaataaaacaaa

Function

symbol description
serpinc1 Predicted to enable serine-type endopeptidase inhibitor activity. Acts upstream of or within cellular response to estrogen stimulus and regulation of blood coagulation. Predicted to be active in extracellular space. Is expressed in liver; yolk; and yolk syncytial layer. Used to study disseminated intravascular coagulation. Human ortholog(s) of this gene implicated in antithrombin III deficiency; disseminated intravascular coagulation; intermediate coronary syndrome; thrombosis; and toxic shock syndrome. Orthologous to human SERPINC1 (serpin family C member 1).

NR:

description
antithrombin-III-like isoform X1

GO:

id name namespace
GO:0030162 regulation of proteolysis biological_process
GO:0010951 negative regulation of endopeptidase activity biological_process
GO:0071391 cellular response to estrogen stimulus biological_process
GO:2000266 regulation of blood coagulation, intrinsic pathway biological_process
GO:0005615 extracellular space cellular_component
GO:0008201 heparin binding molecular_function
GO:0004867 serine-type endopeptidase inhibitor activity molecular_function

KEGG:

id description
K03911 SERPINC1, AT3; antithrombin III

RNA

RNA id representative length rna type GC content exon number start site end site
XM_026930383.2 True 1652 mRNA 0.48 8 12736065 12744758

Neighbor

gene id symbol gene type direction distance location
dph5 dph5,LOC106613590,LOC107715097 coding downstream 59166 12666723 ~ 12676899 (-)
dbt dbt,LOC107588055,LOC107653638 coding downstream 240397 12488208 ~ 12495668 (-)
lrrc39 lrrc39,LOC107592708,LOC107715106,LOC107653639 coding downstream 252014 12479396 ~ 12484051 (-)
osbpl1a LOC108271178,LOC108429508 coding downstream 262617 12436097 ~ 12473448 (-)
cart1 LOC108270656 coding downstream 301896 12431859 ~ 12434169 (-)
stil stil coding upstream 38561 12783319 ~ 12802687 (-)
klf2a LOC108271322 coding upstream 102093 12846851 ~ 12849646 (-)
fam32a fam32a coding upstream 198668 12943426 ~ 12946820 (-)
LOC113536692 NA coding upstream 279643 13024401 ~ 13032544 (-)
lpl lpl,LOC108271131,LOC107588078,LOC107665505,LOC107561902,LOC107715086 coding upstream 293232 13037990 ~ 13046848 (-)
G180434 vcam1 non-coding downstream 110494 12623102 ~ 12625571 (-)
G180429 vcam1 non-coding downstream 116414 12575961 ~ 12619651 (-)
G180428 vcam1 non-coding downstream 117532 12602176 ~ 12618533 (-)
G180430 NA non-coding downstream 151295 12579501 ~ 12584770 (-)
G180392 NA non-coding downstream 227833 12507941 ~ 12508232 (-)
G180541 NA non-coding upstream 2576 12747334 ~ 12747544 (-)
G180574 NA non-coding upstream 136897 12881655 ~ 12881911 (-)
G180626 NA non-coding upstream 231829 12976587 ~ 12980695 (-)
G180629 safb2 non-coding upstream 237254 12982012 ~ 12984113 (-)
G180627 NA non-coding upstream 242029 12986787 ~ 12987523 (-)
G180485 s1pr1,LOC107715096,LOC107592715 other downstream 15589 12717361 ~ 12720476 (-)
ncln ncln other downstream 704059 12020412 ~ 12032006 (-)
fxr1 fxr1 other downstream 846916 11862989 ~ 11889149 (-)
LOC117598402 NA other downstream 1204032 11527957 ~ 11532033 (-)
LOC113536577 NA other downstream 1217671 11510846 ~ 11518394 (-)
rc3h1a rc3h1,LOC108429496 other upstream 7320 12752078 ~ 12782535 (-)
rpp21 LOC108271386 other upstream 494965 13239723 ~ 13243200 (-)
ptprsa ptprs,ptprd,LOC107559826,LOC107679075 other upstream 802156 13546914 ~ 13783127 (-)
LOC113527598 LOC108271251,LOC108441295,LOC107742801 other upstream 1613762 14358520 ~ 14361647 (-)
rx1 LOC108270609 other upstream 1663968 14408726 ~ 14415069 (-)

Expression


Co-expression Network