AMCG00014728 (gsk3b,LOC107559500,LOC107721573,LOC107551994,LOC107715908)


Basic Information

Item Value
gene id AMCG00014728
gene name gsk3b,LOC107559500,LOC107721573,LOC107551994,LOC107715908
gene type coding
species bowfin (Amia calva)
category of species ecological fish

Chromosome Information

Item Value
chromosome id CM030128.1
NCBI id CM030128.1
chromosome length 42883965
location 28905901 ~ 28916634 (+)
genome version AmiCal1_2021_bowfin_Genome

Sequence

>AMCG00014728
aaGGATGAAGTCTATCTCAACCTGGTCCTGGACTACGTTCCTGAAACAGTATACAGAGTCGCCAGACATTACAGCCGAGCCAAACAGACACTCCCTATGATCTATGTGAagTTGTACATGTACCAGCTATTCCGGAGTTTAGCCTATATCCATTCCTTTGGAATTTGCCATCGGGACATCAAACCACAGAATCTGCTGCTGGACCCAGAGACAGCCGTACTCAAACTGTGTGATTTTGGAAGTGCAAAGCAGTTAGTCAGAGGAGAGCCCAATGTGTCCTACATCTGCTCGCGGTACTACAGGGCGCCAGAGCTGATTTTTGGCGCTACAGATTATACCTCTAGTATAGACGTCTGGTCAGCTGGGTGCGTGCTAGCCGAACTGTTGCTAGGACAACCGATCTTCCCTGGTGACAGTGGAGTGGATCAGCTGGTGGAAATCATCAAGGTCCTTGGCACACCAACAAGGGAACAGATTCGAGAGATGAATCCCAATTACACTGAATTCAAATTCCCCCAGATTAAGGCGCATCCATGGACTAAGGTCTTCCGGCCTCGCACCCCCCCGGAGGCCATCGCGCTGTGTAGCCGGCTGCTGGAGTACACGCCCACTGCCCGCCTCACCCCCCTGGAAGCCTGTGCGCACTCCTTCTTCGACGAGCTACGGGACCCAAATATTAAGCTACCAAATGGACGGGAGAAGCCCTCTCTCTTCAACTTCACCACTCAAGAGCTGTCCAGTAACCCCTCACTGGCCTCCATCCTGATCCCGGCCCACGCCCGCAGTCAGGCCGGAGCCTCCACTCCCACCAACGCCTCGGCCACCTCAGGTCAGGTGCACCCGCCCGGCAGCCTCCCCTCCTAA

Function

symbol description
gsk3b Enables several functions, including NF-kappaB binding activity; enzyme binding activity; and protein kinase activity. Involved in several processes, including pallium development; protein phosphorylation; and regulation of neuron death. Acts upstream of or within several processes, including ER overload response; peptidyl-serine phosphorylation; and positive regulation of protein export from nucleus. Located in several cellular components, including centrosome; nucleoplasm; and plasma membrane. Part of beta-catenin destruction complex. Is active in glutamatergic synapse. Implicated in Alzheimer's disease; amyotrophic lateral sclerosis; bipolar disorder; and schizophrenia. Biomarker of colorectal adenocarcinoma; degenerative disc disease; endometrial carcinoma; and schizophrenia.

NR:

description
PREDICTED: glycogen synthase kinase-3 beta-like isoform X2

GO: NA

KEGG:

id description
K03083 GSK3B; glycogen synthase kinase 3 beta

RNA

RNA id representative length rna type GC content exon number start site end site
AMCG00014728 True 864 mRNA 0.55 7 28905901 28916634

Neighbor

gene id symbol gene type direction distance location
AMCG00014727 gsk3b,LOC107703010 coding upstream 14933 28881917 ~ 28890968 (+)
AMCG00014725 lrrc58,LOC106574305 coding upstream 126611 28767435 ~ 28779290 (+)
AMCG00014726 LOC103028151 coding upstream 139811 28695811 ~ 28766090 (+)
AMCG00014723 NA coding upstream 296714 28591078 ~ 28609187 (+)
AMCG00014724 NA coding upstream 314941 28583469 ~ 28590960 (+)
AMCG00014734 NA coding downstream 179495 29096129 ~ 29110638 (+)
AMCG00014733 NA coding downstream 204317 29120951 ~ 29129042 (+)
AMCG00014737 NA coding downstream 391306 29307940 ~ 29321592 (+)
AMCG00014741 LOC106586690,LOC106582147,LOC106575755 coding downstream 466854 29383488 ~ 29398221 (+)
AMCG00014740 LOC107557921 coding downstream 483998 29400632 ~ 29421379 (+)
G72329 NA non-coding upstream 73926 28831756 ~ 28831975 (+)
G72273 NA non-coding upstream 327168 28526788 ~ 28578733 (+)
G72208 NA non-coding upstream 564184 28337291 ~ 28341717 (+)
G72173 NA non-coding upstream 605088 28297669 ~ 28300813 (+)
G72169 NA non-coding upstream 608417 28240566 ~ 28297484 (+)
G72341 NA non-coding downstream 2342 28918976 ~ 28921290 (+)
G72353 NA non-coding downstream 64488 28981122 ~ 28985576 (+)
G72354 NA non-coding downstream 72973 28989607 ~ 28991299 (+)
G72409 NA non-coding downstream 220495 29137129 ~ 29137353 (+)
G72415 NA non-coding downstream 240391 29157025 ~ 29160425 (+)
AMCG00014729 NA other upstream 67991 28797049 ~ 28837910 (+)
G72175 LOC102776245 other upstream 601828 28302373 ~ 28304073 (+)
AMCG00014703 ndp,LOC107565935,LOC106586792 other upstream 1026101 27868703 ~ 27879800 (+)
AMCG00014704 fundc1,LOC102219358,LOC102292135,LOC102776203,LOC103475814,LOC106926458 other upstream 1064030 27835503 ~ 27841871 (+)
AMCG00014687 NA other upstream 1994664 26904877 ~ 26911237 (+)
AMCG00014739 NA other downstream 331241 29247875 ~ 29256354 (+)
AMCG00014738 NA other downstream 351695 29268329 ~ 29279149 (+)
AMCG00014757 LOC105927538,LOC107688735,LOC105016589,LOC104946938,LOC107716767,LOC107676512,LOC107099897,LOC103140352 other downstream 926833 29843467 ~ 29846586 (+)
G72605 NA other downstream 934816 29851450 ~ 29851821 (+)
AMCG00014777 NA other downstream 1847717 30764351 ~ 30812287 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_037654 gsk3ba coding NC_007120.7 CM002893.2 9577743 ~ 9671244 (-)
grasscarp (Ctenopharyngodon idella) CI01000037_04313204_04343186 GSK3B coding CI01000037 null 4312626 ~ 4343186 (-)