XLOC_006130 (mgme1)


Basic Information

Item Value
gene id XLOC_006130
gene name mgme1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007124.7
NCBI id CM002897.2
chromosome length 52186027
location 33655404 ~ 33658885 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00012072
CAGTATATCCAGTTCAATCTGCGCTACGTTTGAATGTGGCATGTAGCAACATCATGCCTGCTGATCCGCACTATaactttttggtttgtttattttaatttacatgtccattattttatttttcaaagcatgcGAAACCATATTTAAACATCATAACAGTCACAGCACGTGAACACAAAGAACTGTTAATACGATgcaggtaacgttattgaggcAGTTGGCACAATACAAGTGTGTGAGATCAATAGGTTTCACCCCTGGTCGGTTCTCGAGGGTGGACAACTTTTCAACAAGCTGTCAATGGCGAGCACGCAAAAAGGTCAGTCAGTACAGCACAGTGGACACGGAGCGCTACTCATCCCTGGTTCGTGCGGTGTTGACAAAAACCAGCTCACAGACTCCTGAAAGCATCGAGGATGAAGACTCTAAGCTGTTTGGACCAATAATAAGATCCAAACCTCATTCTCAGCAGCCCAGAGAACCTAAAATCCTGCATCCACTATTAAATGAGGCCAAAGGTCTGTCAGAGTATGTCCCAGGACCTTTGGCTCATATACCATTAGAGAGGGACTCTAATAAGACACTTATACCCAGTGTCACCCGCATCCTCCAGCAGACGATGCCACCTGAACAGGCCTTTTACCTGGAGAGGTGGAGGAGAAGGATGATTGCTGAACTTGGAGAGGAAGGCTTTAAAGAATACAGCTTGAACATTTTCAGACAAGGAAAGCTGTTTCATGCTGCTATTGAGAACACTTTCACTCAGGAAACTGTCTCTAAGGAGGACACTGAGTGTCCAGCAGAGGTGTCCGGATATATGGAGAGTGTTTCTCATGTGTTGACTGATATATCAGGAGTGAGAGCTATTGAAAGTGCTGTACATCATTCAGCATTACAGTATCTGGGCATTGTAGATTGTGTTGCCCAATACAGAGGTTCATTGTGTGTCATTGACTGGAAGACCTCAGAGAAGCCGAAGCCTCTACTTCACAATACTTATGACAATCCATTACAAGTAGCTGCATACACTGGTGCCTTGAACAGTGACAACAACTACAGCTACCAGGTAGATAATGGCTTAATTGTGGTAGCCTACAAAGACGGTTCACCTGCACATGCTCACTTTCTGAACTCCAAGCAAATTAAGCAATTCTGGGAGAAATGGCTTCTTCGACTAGAAGagtttgcagaaaaataaaacccCTTTGACTAGCATAACAATTCTAGATAATGCTACACAATGTGTAgttcaactgtaaatgtttttcatttgatacaaagaataaacatttgtgttttacaca

Function

symbol description
mgme1 Predicted to enable single-stranded DNA exodeoxyribonuclease activity. Predicted to be involved in mitochondrial DNA replication. Predicted to act upstream of or within mitochondrial DNA repair. Predicted to be active in mitochondrion. Is expressed in several structures, including digestive system; lens; solid lens vesicle; vasculature; and ventral mesoderm. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 11. Orthologous to human MGME1 (mitochondrial genome maintenance exonuclease 1).

GO:

id name namespace
GO:0043504 mitochondrial DNA repair biological_process
GO:0006264 mitochondrial DNA replication biological_process
GO:0005739 mitochondrion cellular_component
GO:0004518 nuclease activity molecular_function
GO:0004527 exonuclease activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0008297 single-stranded DNA exodeoxyribonuclease activity molecular_function

KEGG:

id description
ko03029 Mitochondrial biogenesis

ZFIN:

id description
ZDB-GENE-041212-68 Predicted to enable single-stranded DNA exodeoxyribonuclease activity. Predicted to be involved in mitochondrial DNA replication. Predicted to act upstream of or within mitochondrial DNA repair. Predicted to be active in mitochondrion. Is expressed in several structures, including digestive system; lens; solid lens vesicle; vasculature; and ventral mesoderm. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 11. Orthologous to human MGME1 (mitochondrial genome maintenance exonuclease 1).

Ensembl:

ensembl_id ENSDARG00000016656

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00012072 True 1304 mRNA 0.42 4 33655404 33658885

Neighbor

gene id symbol gene type direction distance location
XLOC_006128 cfl1l coding upstream 45977 33606739 ~ 33609427 (+)
XLOC_006127 jag2a coding upstream 103705 33488032 ~ 33551699 (+)
XLOC_006126 ftr81 coding upstream 186707 33462232 ~ 33468697 (+)
XLOC_006125 ftr80 coding upstream 196614 33452096 ~ 33458790 (+)
XLOC_006124 brf1a coding upstream 205765 33368140 ~ 33449639 (+)
XLOC_006131 CABZ01087953.1 coding downstream 29589 33688474 ~ 33695296 (+)
XLOC_006132 macrod2 coding downstream 44899 33703784 ~ 34558921 (+)
XLOC_006133 CR524481.1 coding downstream 767363 34426248 ~ 34426365 (+)
XLOC_006134 tasp1 coding downstream 1030778 34689663 ~ 34750299 (+)
XLOC_006135 NA coding downstream 1093289 34752174 ~ 34984913 (+)
XLOC_006116 NA non-coding upstream 550176 33104911 ~ 33105228 (+)
XLOC_006113 BX470227.1 non-coding upstream 670635 32984654 ~ 32984769 (+)
XLOC_006112 NA non-coding upstream 738478 32906643 ~ 32916926 (+)
XLOC_006111 CR936241.1 non-coding upstream 808795 32846493 ~ 32846609 (+)
XLOC_006105 CR769766.1 non-coding upstream 1262905 32392383 ~ 32392499 (+)
XLOC_006136 CR376850.1 non-coding downstream 1224361 34883246 ~ 34883370 (+)
XLOC_006137 CR376850.2 non-coding downstream 1310634 34969519 ~ 34969645 (+)
XLOC_006140 CU681845.1 non-coding downstream 1824733 35483618 ~ 35522176 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000012_07113504_07118919 MGME1 coding CI01000012 null 7113356 ~ 7119168 (-)