XLOC_000650 (actr2a)


Basic Information

Item Value
gene id XLOC_000650
gene name actr2a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 51407520 ~ 51428106 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00001110
GGTGCAGAGATCAGGGCGGATTCACCGAGTCTGGACAAAAATGGACAGCCAGGGCAAAAAAGTGGTGGTCTGTGACAACGGGACAGGGTTCGTGAAGTGTGGATATGCTGGCTCTAATTTCCCAGAGCACATATTTCCGGCTCTGGTCGGGAGGCCGATCATCCGCTCCACTGCCAAAGTGGGAAACATCGAGATCAAGgacCTGATGGTGGGCGACGAGGCGAGTGAACTGCGCTCCATGCTGGAGGTGAACTACCCCATGGAGAACGGCATCGTGAGGAACTGGGATGACATGAAGCACTTGTGGGATTACACCTTCGGCCCGGAGAAACTCAACATCGACTCAAGAAACTGCAAGATCCTGCTGACCGAGCCCCCCATGAACCCCACCAAAAACAGAGAGAAGATCATCGAGGTGATGTTTGAGACCTATCAGTTCTCTGGAGTTTATATCGCCATCCAGGCCGTCCTTACACTCTACGCTCAAGGTCTGCTGACGGGTGTAGTTGTGGACTCTGGCGACGGCGTCACTCATATTTGTCCCGTGTACGAAGGCTTTTCTCTTCCTCATCTCACTCGCCGTCTGGACATCGCCGGAAGAGACATCACACGCTACCTCATCAAGCTGCTGTTGTTGAGAGGTTACGCCTTCAACCACTCGGCAGACTTCGAGACGGTGAGGATGATGAAGGAGAAGCTGTGTTACGTGGGTTATAACATCGAGCAGGAGCAGAAGCTTGCGCTGGAGACCACTGTTCTGGTGGAGTCTTACACGCTGCCGGACGGGAGGGTGATTAAAGTTGGCGGCGAGCGGTTCGAGGCTCCTGAAGCTCTGTTTCAGCCTCACCTCATTAATGTGGAGGGTGTGGGGGTCGCTGAACTGCTCTTCAACACCATCCAGGCTGCAGACATCGACACCAGGGCTGAGTTTTACAAGCACATTGTTTTGTCGGGCGGCTCCACCATGTATCCCGGTCTGCCGTCTCGTCTGGAGCGAGAACTCAAACAGCTTTACCTGGAGAGAGTGTTGAAGGGAGACGTCGACAAGCTCTCGAAGTTTAAGATCCGCATTGAGGATCCTCCACGTCGTAAACACATGGTGTTTTTGGGTGGCGCAGTGCTAGCAGACATCATGAAGGACAAAGACAACTTCTGGATGACCAGAGAGGAGTATCAAGAGAAGGGCACGCGTGTGCTGGAGAAACTGGGTGTCACTGTTAGATAAATCAAACACATTctcgcataaacacacacaaatacacacaaagcatcacacactcacactcccAGTCGCCGGGTGGCATTTTGGCAGCGTAAATGCACCaatgtttttttcaaaagatgatGAGGAAATACTTGAGAACCACAAACAAATACTTGAACTTCCTTTTAcaatccaaaaatgaaaagtgcTTAAAGTTTGTACGACATTCCAAATGTAAAGGCTCATATCAGTGATATTGAGTGAATTGCTCACGAAAGCCGTTTATGCTGCCAAAATGAATCCACAAAAGCACCACCATATCATGACCTGTTTGTTTCGAGTCCTGTCCGCTTTATGAATTCTCATCGACTCTAACAAAGTCAAATATCACTCAAAagagagtttaaaaaaattaaacatgaggATGTTGTGTaagtaaacaataaaaagatGTATTTTTAAGAGAGGTTTCTTTGGTAAGAAGTTGTTTTTGTAATGATAAAAAAAGTCGTTGCAGCCAATTAGCTAATAAAAATGAAGACTATAAGAATGGTGGCTGATGGTATCAAACATACAGACGTTCTGGCAGAAGTGTCTACTTTTTACCTTTAATTTTCTGCAATGGCTTTCTCTCAGTGTTGTTAGATGTGCGCTTCATCTGATTTCCTGAAAGTAAAGAGGGAAATGCGGTTATGACCTGGACCAACTTCTctgaatattacaatattttacgAGTGCTCTGAGCTCAAATAATGTCAATGAGGATGCTTTAAATAAACTAACTATGAGCATCGCTAATCTGCTTAGCTGTTAGGATTTGAAAGTCATATAGACAGGTCGTTCGCAATTAGATCTGTGTTTTAGTCTAAAGGACATTTATAAACGGTAGTATCAGTTTCAGACTGTGTTTGAAAGGGAAGTGATAATGTTCTGCCGCATGTTTTGCGTACAGTTATAGCTGAAAACTAGAAGCTCATTTCCGCATCTGTATCTCATCAAATTCACATTTTAGGATCAAAATGGACTTTTCTTTTGCATTGACATAATTTTGACAATTAGTCACTTTTTTGTTTCTATTGTCATTACCGTAATGCTAATATAATGAAATTATCAATTAcataatgcattattttaataaaaaaatatatacatgtattgGCGTGATGACATTATTTTCATGACGATTAAGCTCTTTTTTGGTCTGTATTGTCATTACCGTAATGTTATTACGATAGAATTCTTATCAACATCTTGCCTTTAAATCTgtcatttatattaaaacaatgcattttgACATTATTGTCATGACAATTAAGCACTCTTTTTGTCTGAATTGTCATTACCGAATTGCTAATACAATGGAATTCTCATTCACATAATACATTAttgttataaaaattataattcatTGACATGGTATTGTGACAATTAGGCACTTTTATTGTCTGTATTGTCATTATCGTAATGCTAATATAATGGATTTCTCATTAACATCTTGCAGATACGTTTAACGTTTTTATTCAATTAATGTATCTTAACATAATTTTCATGAAAATTTAGCACTTTTTGCCTGACTTGTCATTAACGTAATGCTAATATAATGGGATTCTCATTAACATCTTGCCCATACATCTATCATATAATGGAACTATCATTAACATCATGTTAATACagctttcatttttattaaaataatgcattttgacattattttcttAACAATTAAGAACTTTTTTTGTCTGAATTTTCATTACCGTAATGCTAATATAATGGAATCCTCATTACCATCATGCCAATTACAGctatcattttttaaacaatgcatTTTGACATTGTTTATGACAATTAGGAACAGTTTTGTCTGAATTGTCAATACCGTAATGCTAATATAATGGAATTATCATTGACATCATGCCAATACATCTataattttttcttaaaataatgcatttagaCATTATTTTTATGACAATTAGGCTCTTTTTTTTGTCTGAATCGTCATTACCATAATGCTAATATAATGGAATTATCATTACCATCTGGCCAATACAGCTAGCGTTTTTATAAAGTTATACATTTTGATGCTATTTTCATGACAATTAAGCTCCTTTTTTGTCTGAATTGTCATTACCATAATGCTAagataatgtaatttttattaccACCATGCAAATACAtgcataatttttattaatttaatgcataaaataaaaaaaattactctaATGGAAAAAAACTACAATCATTACCATAAAGAAACATTTACCTTGATTCAAAGtcaaaaataaatagtgaaaatacaGTACTCTTTCGGTAATATagtaaacaaatactgtatttactagCAATGAGAATcagaaaatatatgtaaaattgaAATTTTTGTATGGAAATGATTATTTTGGAATTAATGTTTATAATCGTTTATAAAAATGTAGCTGTAGTTTTTTTAAGAATGAAAATTAGACTTGGAATAAAAATGATAGTATCCAATAAGAAATGTAAATTAGTGGAAATGACAAAATATAGAGGAACAAAATGTGTTACGGTAATGAGAATTTCTAATGTAAATTGGTGTAATGTCAATGCAAAAAAGCATTCTGATTCTGAAATTAGATggggttttttttccttttttttttctttgcaagaTTCACATTTGGAGAGTTGGCCATAAATCATCCAGATTAGCTGCAGCAGTGCATTTAGTTGCAGCTCACGCATGCATTTCTCACATGCATCACTCCATGCAGCTTCAGTTAGTGTTGCTCATTCCATTGCAATACCCCAGATCCTTTTCATCAGCtcatttattttagtgttttaatgAGTCTCAATCGTGTTTTACTCCCTCGAGGAACTTCATGGTTGTTCACAGTCTCAACATGTTTTTTACTTTccttgcatttaaagggatagttcacctttaaaattaaaatgtgctcaCCATTTCCTcaaagtgtttccaaacctgtttgttttttcttttgttaaactgctggaaacctgtaaccattgacttctatagtgggaaaagcaaatactgaaggaaaaactcaattgatgacaatattttcattttcaggtgaactatcccttcaacagttttttgtttatttgttttttttttcttctctggtGGTTGTCGGGTAATTTTCGTGTCCTAGTCGTGCGGCATCTAACAGTCTGAAAATGAAGGCGTCTCTGGTTAGACGCTTCATTCCCAGACCCAAGACAGCCATGATGTAACGGTTTACTGCCTGTTTGTAAAAAGAATGACACAATAATGACGGTAATGataatgatgaaaataattttaGTGTTTGTACTCGTTGACAGCTGTTTTGAAAGCTGGATCAGTGATGTTTCTGTGTTTGGCTTTGGGTTTGTTCACACTCGGACTCTTCACATGTGGAACAAACAGTACGACGACTCCATTGATTTCACTTATGCGTGCTTTCAGTGCCAAGTTTGGGTATTGtagtcattttttttgtttgttttctgcattttttttttctgttcgtTGCGTACTGCCAGACCActgatttaaataaagaaaattgatTTATAA

Function

symbol description
actr2a Predicted to enable ATP binding activity and actin binding activity. Predicted to contribute to actin filament binding activity. Predicted to be involved in Arp2/3 complex-mediated actin nucleation; positive regulation of double-strand break repair via homologous recombination; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within actin filament organization. Predicted to be located in cytoplasm; nucleus; and site of double-strand break. Predicted to be part of Arp2/3 protein complex. Predicted to be active in actin cortical patch. Orthologous to human ACTR2 (actin related protein 2).

GO:

id name namespace
GO:0007015 actin filament organization biological_process
GO:0034314 Arp2/3 complex-mediated actin nucleation biological_process
GO:1905168 positive regulation of double-strand break repair via homologous recombination biological_process
GO:0045944 positive regulation of transcription by RNA polymerase II biological_process
GO:0042995 cell projection cellular_component
GO:0035861 site of double-strand break cellular_component
GO:0005856 cytoskeleton cellular_component
GO:0005885 Arp2/3 protein complex cellular_component
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005524 ATP binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0051015 actin filament binding molecular_function
GO:0003779 actin binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040426-2894 Predicted to enable ATP binding activity and actin binding activity. Predicted to contribute to actin filament binding activity. Predicted to be involved in Arp2/3 complex-mediated actin nucleation; positive regulation of double-strand break repair via homologous recombination; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within actin filament organization. Predicted to be located in cytoplasm; nucleus; and site of double-strand break. Predicted to be part of Arp2/3 protein complex. Predicted to be active in actin cortical patch. Orthologous to human ACTR2 (actin related protein 2).

Ensembl:

ensembl_id ENSDARG00000052438

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00001110 True 4778 mRNA 0.37 9 51407520 51428106

Neighbor

gene id symbol gene type direction distance location
XLOC_000649 atg4da coding upstream 989 51386649 ~ 51406531 (+)
XLOC_000648 mast1a coding upstream 29670 51312752 ~ 51377850 (+)
XLOC_000647 ndufaf5 coding upstream 178064 51221320 ~ 51229456 (+)
XLOC_000646 btbd3a coding upstream 209919 51191049 ~ 51197601 (+)
XLOC_000645 srd5a2a coding upstream 334392 51066671 ~ 51073128 (+)
XLOC_000651 BX547996.1 coding downstream 37362 51465468 ~ 51465582 (+)
XLOC_000652 meis1a coding downstream 46988 51475094 ~ 51525086 (+)
XLOC_000653 etaa1 coding downstream 109144 51537250 ~ 51545917 (+)
XLOC_000654 zgc:165656 coding downstream 187400 51615506 ~ 51627129 (+)
XLOC_000655 CU464066.1 coding downstream 255413 51683519 ~ 51683618 (+)
XLOC_000643 NA non-coding upstream 388969 51015858 ~ 51018551 (+)
XLOC_000640 NA non-coding upstream 453962 50943592 ~ 50953558 (+)
XLOC_000638 BX855617.1 non-coding upstream 553042 50854364 ~ 50854478 (+)
XLOC_000637 NA non-coding upstream 599072 50733156 ~ 50808448 (+)
XLOC_000633 NA non-coding upstream 875826 50528134 ~ 50531694 (+)
XLOC_000656 NA non-coding downstream 266645 51694751 ~ 51717215 (+)
XLOC_000658 NA non-coding downstream 324872 51752978 ~ 51826020 (+)
XLOC_000660 NA non-coding downstream 422455 51850561 ~ 51864765 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000301_01311781_01320619 ACTR2B, ACTR2, ACTR2.S, ACTR2A coding CI01000301 null 1311548 ~ 1321048 (+)
bowfin (Amia calva) AMCG00001649 actr2,LOC108423375,LOC106585927,LOC104930021,LOC108441254,LOC105021597 coding CM030143.1 CM030143.1 10677362 ~ 10694822 (-)