XLOC_000645 (srd5a2a)


Basic Information

Item Value
gene id XLOC_000645
gene name srd5a2a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 51066671 ~ 51073128 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00001096
ATTTATTAACTGCAGTTGTTTATGTGCACTTGTACATTTCATGCCAGAACCAATAAATCATAGTGGGAGGAACCTTATGATTTTACATCAGAGTGGTGTCACTTTAACTGCACACATCAAGACGGAGAAGACAGCAGGGCACTGAGAAACACGCACAGCAATGCTCTGTCAGGAAAACACTGTTCACTTTGGCAGCTGGGCTTTTGTAGTCGGTGGATTGCTTTACCTTCTGAAACAACTGACCACGCAAACGGCGTACGGACGCTATGTGGACACAAAATCCCCTGGGTTGATGGTCCCAGCCAGGGCAGGCTGGTTTATACAGGAACTTCCTTCATTCTTAGTGCCCGTGCTGTTGTTTTTTGCAACGGAAAGTTTGCCAGGCGTTGGAAAACACATACTGTTCTGGACATTTTGTTTGCACTACTTTCAAAGGACATTTGTGTATTCACTGCTGACTAAAGGCCGTCCATCTCCTCTCCATATTGTGGTCAGTGCGGTGGTCTTCTGCTCGATCAATGGCTTTCTGCAGGGTCACTACATGCTGCACTGCACACAATACAGCAGCGACTGGCTCACAGACACACGCTTCATCACTGgtttgttggtgtttttgtgtggaatGGCCATCAATATCCACAGTGACTATATTTTACGAAACCTGAGGAAACCCGGAGAGGTCAGCTATAAAATCCCAAGAGGAGGGCTGTTTGAGCTGGTGTCCGGCGCCAACTTCTTCGGGGAGATTGTTGAATGGTGTGGATACGCCGTGGCCAGCTGGTCATTTCCTGCTTTCTCCTTCGCCCTGTTCACCATCTGCTCCATCGGGCCTCGAGCCTACCATCATCACAGgTATTACTTGGAGAAATTTAAGGATTACCCCAAATCAAGAAAGGCTGTGATCCCTTTCCTGCTATAAGAAatcaaaaaaggaaaaacatCCTAAAATAAGTGCACAGAGTCAGCCATCTACTCCAGTGATGTTTAAACTCTCCTAGTCACATTTACCACCAAGAGACATTTCTACAtttcttgtatttattttttttaaatacatgtttacatctGTACAAAGTGATCTACACACACTCGTCTTGTCAGAAAAACAAATGATCAGTAATAAATGATTACAACCACTCAAGTGTCACTACAAAA
>TCONS_00001097
ACACATCAAGACGGAGAAGACAGCAGGGCACTGAGAAACACGCACAGCAATGCTCTGTCAGGAAAACACTGTTCACTTTGGCAGCTGGGCTTTTGTAGTCGGTGGATTGCTTTACCTTCTGAAACAACTGACCACGCAAACGGCGTACGGACGCTATGTGGACACAAAATCCCCTGGGTTGATGGTCCCAGCCAGGGCAGGCTGGTTTATACAGGAACTTCCTTCATTCTTAGTGCCCGTGCTGTTGTTTTTTGCAACGGAAAGTTTGCCAGGCGTTGGAAAACACATACTGTTCTGGACATTTTGTTTGCACTACTTTCAAAGgtttgttggtgtttttgtgtggaatGGCCATCAATATCCACAGTGACTATATTTTACGAAACCTGAGGAAACCCGGAGAGGTCAGCTATAAAATCCCAAGAGGAGGGCTGTTTGAGCTGGTGTCCGGCGCCAACTTCTTCGGGGAGATTGTTGAATGGTGTGGATACGCCGTGGCCAGCTGGTCATTTCCTGCTTTCTCCTTCGCCCTGTTCACCATCTGCTCCATCGGGCCTCGAGCCTACCATCATCACAGgTATTACTTGGAGAAATTTAAGGATTACCCCAAATCAAGAAAGGCTGTGATCCCTTTCCTGCTATAAGAAatcaaaaaaggaaaaacatCCTAAAATAAGTGCACAGAGTCAGCCATCTACTCCAGTGATGTTTAAACTCTCCTAGTCACATTTACCACCAAGAGACATTTCTACAtttcttgtatttattttttttaaatacatgtttacatctGTACAAAGTGATCTACACACACTCGTCTTGTCAGAAAAACAAATGATCAGTAATAAATGATTACAAC
>TCONS_00001098
GAAACACGCACAGCAATGCTCTGTCAGGAAAACACTGTTCACTTTGGCAGCTGGGCTTTTGTAGTCGGTGGATTGCTTTACCTTCTGAAACAACTGACCACGCAAACGGCGTACGGACGCTATGTGGACACAAAATCCCCTGGGTTGATGGTCCCAGCCAGGGCAGGCTGGTTTATACAGGAACTTCCTTCATTCTTAGTGCCCGTGCTGTTGTTTTTTGCAACGGAAAGTTTGCCAGGCGTTGGAAAACACATACTGTTCTGGACATTTTGTTTGCACTACTTTCAAAGGACATTTGTGTATTCACTGCTGACTAAAGGCCGTCCATCTCCTCTCCATATTGTGGTCAGTGCGGTGGTCTTCTGCTCGATCAATGGCTTTCTGCAGGGTCACTACATGCTGCACTGCACACAATACAGCAGCGACTGGCTCACAGACACACGCTTCATCACTGGTACagcatcactcactcactcactccctcactcacacGCAGTCAGTGAAGGCTGCTGCTACATTGGTTACAACCAGTGTTGAGTAAGTTACTTCAGAAGCTAAATTAATTACTGATTCAAACTGTAAATTTTTCCTGCAAAAGGtacttttaaaattacattatgtGAAATTTAGTAAAGGGCGACATGgcgactcagtggttagcactgtctcctcacagcaagagcctctactgggtcagttggcatttctgtgtggagttttcatgttctctcgtgttggcgtgggttttcctccgggtgctctggtttcccccagtccaaacacatgcgcaacagaggaattgaataaactaaattggccaaagagtatgtgtgtggacgagtgtgtatgggtgtttcccagtactgggttgcagctggaagggcatccgttgtgtaaaacacatgctggaatagttgacggttcattcaatctaattatttaaaaatgaaaagcaaTCCCTTACTCTAAATTTTCAATGGAAAAGTCGTTCAATTACAGCGATTAATTAAACCCAACACTGGTTACAACTCACAAAAACACTCCATACtcaataaaaatgaatgtttcttacaggtttgttggtgtttttgtgtggaatGGCCATCAATATCCACAGTGACTATATTTTACGAAACCTGAGGAAACCCGGAGAGGTCAGCTATAAAATCCCAAGAGGAGGGCTGTTTGAGCTGGTGTCCGGCGCCAACTTCTTCGGGGAGATTGTTGAATGGTGTGGATACGCCGTGGCCAGCTGGTCATTTCCTGCTTTCTCCTTCGCCCTGTTCACCATCTGCTCCATCGGGCCTCGAGCCTACCATCATCACAGgTATTACTTGGAGAAATTTAAGGATTACCCCAAATCAAGAAAGGCTGTGATCCCTTTCCTGCTATAAGAAatcaaaaaaggaaaaacatCCTAAAATAAGTGCACAGAGTCAGCCATCTACTCCAGTGATGTTTAAACTCTCCTAGTCACATTTACCACCAAGAGACATTTCTACAtttcttgtatttattttttttaaatacatgtttacatctGTACAAAGTGATCTACACACACTCGTCTTGTCAGAAAAACAAATGATCAGTAATAAATGATTACAACCACTCAAGTGTCACTACAAAA

Function

symbol description
srd5a2a Predicted to enable 3-oxo-5-alpha-steroid 4-dehydrogenase activity. Predicted to be involved in steroid biosynthetic process. Predicted to act upstream of or within cell differentiation; sex differentiation; and steroid metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Is expressed in intestinal bulb and liver. Human ortholog(s) of this gene implicated in hypospadias and prostate cancer. Orthologous to human SRD5A2 (steroid 5 alpha-reductase 2).

GO:

id name namespace
GO:0006629 lipid metabolic process biological_process
GO:0008202 steroid metabolic process biological_process
GO:0006694 steroid biosynthetic process biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity molecular_function
GO:0016491 oxidoreductase activity molecular_function
GO:0047751 cholestenone 5-alpha-reductase activity molecular_function
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-050417-199 Predicted to enable 3-oxo-5-alpha-steroid 4-dehydrogenase activity. Predicted to be involved in steroid biosynthetic process. Predicted to act upstream of or within cell differentiation; sex differentiation; and steroid metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Is expressed in intestinal bulb and liver. Human ortholog(s) of this gene implicated in hypospadias and prostate cancer. Orthologous to human SRD5A2 (steroid 5 alpha-reductase 2).

Ensembl:

ensembl_id ENSDARG00000043587

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00001096 False 1155 mRNA 0.44 5 51066671 51073128
TCONS_00001097 False 859 nonsense_mediated_decay 0.44 4 51066782 51073107
TCONS_00001098 True 1630 lncRNA 0.43 4 51066816 51073128

Neighbor

gene id symbol gene type direction distance location
XLOC_000644 dpy30 coding upstream 24339 51039558 ~ 51042332 (+)
XLOC_000643 NA coding upstream 48120 51015858 ~ 51018551 (+)
XLOC_000642 ugp2a coding upstream 51044 50997156 ~ 51015627 (+)
XLOC_000641 mdh1aa coding upstream 75782 50968908 ~ 50990889 (+)
XLOC_000640 NA coding upstream 113113 50943592 ~ 50953558 (+)
XLOC_000646 btbd3a coding downstream 117921 51191049 ~ 51197601 (+)
XLOC_000647 ndufaf5 coding downstream 148192 51221320 ~ 51229456 (+)
XLOC_000648 mast1a coding downstream 239624 51312752 ~ 51377850 (+)
XLOC_000649 atg4da coding downstream 313521 51386649 ~ 51406531 (+)
XLOC_000650 actr2a coding downstream 334392 51407520 ~ 51428106 (+)
XLOC_000638 BX855617.1 non-coding upstream 212193 50854364 ~ 50854478 (+)
XLOC_000637 NA non-coding upstream 258223 50733156 ~ 50808448 (+)
XLOC_000633 NA non-coding upstream 534977 50528134 ~ 50531694 (+)
XLOC_000651 BX547996.1 non-coding downstream 392340 51465468 ~ 51465582 (+)
XLOC_000655 CU464066.1 non-coding downstream 610391 51683519 ~ 51683618 (+)
XLOC_000656 NA non-coding downstream 621623 51694751 ~ 51717215 (+)
XLOC_000658 NA non-coding downstream 679850 51752978 ~ 51826020 (+)
XLOC_000660 NA non-coding downstream 777433 51850561 ~ 51864765 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location