XLOC_000671 (glb1)


Basic Information

Item Value
gene id XLOC_000671
gene name glb1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 52462068 ~ 52478746 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00001137
AATGATTCTTAGCTTTAGCAGCAACCAAAACAAATGGCATTTGACTTCCGCACCGCTGTTTACCGTTTCAAACACCATGACTCCCGGTGTCGGACTAGTCTCGGTTCTGCTCCTTATCATACCAGCCACCACGTACGCCACAACTCCCACTTTTTCTGTGGATTACCATCGAAACTGCTTTCTTAAAGATGGAGAGCCATTCCGCTACATATCTGGCAGTATCCACTACAGCCGGATCCCTAGAGTCTATTGGAAAGACCGGCTACTCAAGATGTACATGGCTGGATTGAACGCCATCCAGACATATGTGCCGTGGAACTTCCACGAAGCAGTTCCTGGTCAGTACGACTTCAGTGGAGATCGAGATCTGGAGCAATTCCTCCAGCTCTGCCAAGACATCGGCCTGCTGGTCATCATGAGACCAGGACCCTACATATGTGCCGAGTGGGATATGGGTGGTTTGCCTGCCTGGCTGCTGAAAAAAAAGGATATTGTGCTTCGATCATCTGATCCAGATTACCTTGCAGCAGTGGACAAGTGGATGGGGAAGCTGTTGCCAATCATAAAGCGTTACCTGTACCAGAATGGAGGCCCAATCATTACCGTGCAGGTAGAGAATGAGTACGGCAGCTACTTCGCCTGTGATTTTAACTACATGCGTCATCTGAGCCAGTTGTTCCGGTTTTATCTCGGGGAAGAGGCTGTGCTGTTCACTACTGATGGGGCAGGTCTGGGTTACTTGAAATGTGGATCCCTCCAGGGCCTCTACGCCACTGTTGACTTCGGCCCAGGTGCAAATGTAACCGCTGCGTTTGAAGCACAGAGGCATGTTGAGCCACGTGGGCCTTTGGTGAACTCTGAGTTTTACCCCGGCTGGTTGGATCATTGGGGCGAAAAACACTCGGTGGTTCCTACATCTGCTGTAGTCAAGACTCTCAATGAAATTCTGGAAATTGGAGCCAATGTCAACCTGTATATGTTCATCGGTGGAACTAACTTTGGCTATTGGAATGGTGCCAACACTCCTTATGGTCCTCAACCCACCAGCTATGACTATGACTCTCCTCTTACAGAGGCTGGAGATCTCACTGAGAAATATTTCGCCATAAGGGAAGTCATCAAAATGtataaagATGTACCAGAAGGAATTCTGCCTCCATCAACACCTAAATTTGCATATGGAAAAGTGCAAATGAAGAAACTAAAGACTGTGTCAGAGACGTTGGATGTGTTGTCTTTCTCCGGCCCTGTAAAAACACTTTACCCTCCAACATTTATTGAAATGAATCAGGCGTTTGGGTTCGTGCTTTATCAAACTGTGCTACCAGTTAACTGCGTGAAGCCCACGCCGCTGTCGTCCCCTCTGAATGGAGTCCACGATCGGGCATATATTTCCATTGATGGCACTGCTGCTGGTATTTTGGAGAGGAACAAGGCACTCAGCATCAATATAACAGGGAAAGCTGGCAGCCGTGTGGACGTCCTGGTGGAGAACATGGGCAGAATCAACTACGGCAAAGGAATTAATGACTTCAAGGGTCTGGTGTTTAATCTGACACTCGGTGCTGATGTTCTGGTTAACTGGACTGTGTATTCCCTGAGTGTCGATGAAGCAGTCAGCAAGGGTTTGCTTTTAGCTTCAGGCTCCTCCTCCACCAGCTCCACCAGCACACCTCCGCCTGCTCTTTCACCTCCAACCTTCTACACAGGCAGCTTCATCATTCCTGACGGTATCCCTGATCTCCCTCAGGACACCTATATCCAGTTCCCCGACTGGAGGAAGGGTCAAGTGTGGATAAATGGATTTAACGTTGGCCGCTACTGGCCGTCCCGTGGGCCACAGATCACTCTCTTTGTCCCGGCGCACCTGCTCAGCACCTCCGTCCAAAACAACATAACCGTCCTGGAGCTTGAGGCGTCTCCTTGCTCCTCAGGTTCCTGCATGGTGGAGTTCACTGATACTCCTATTTTAAACGGCACCGTGAACGGCCAATACAAGAGACAACTATTCAACAAACAAGACCTCTTTTGAGTTTACAGCCGCTTCCAGTTGCAGAAAttgtttatattgtgcaacaaatTTTGTTCGTTTGAAGGAATCTGAGGGATGACGTTGGAGATCATCAGCACTATATGGATTAAATTACAGCTGGATTGTGTGATCACTGTGAAATATAATATCTTGCAAATGATCAGGGGCTGATCAAGGCTGCTCAGGCACTGTATTATTGAAAAATGTGCAGTAGAAGATGTATATTGCTACTCATTatgatgttaaagggatagttcacccaaaaattaaaccaTTTTCTCACATCTCA

Function

symbol description
glb1 Enables beta-galactosidase activity. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be active in vacuole. Human ortholog(s) of this gene implicated in GM1 gangliosidosis (multiple) and mucopolysaccharidosis IV (multiple). Orthologous to human GLB1 (galactosidase beta 1).

GO:

id name namespace
GO:0008152 metabolic process biological_process
GO:0005975 carbohydrate metabolic process biological_process
GO:0005773 vacuole cellular_component
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds molecular_function
GO:0004565 beta-galactosidase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0016798 hydrolase activity, acting on glycosyl bonds molecular_function

KEGG:

id description
ko00052 Galactose metabolism
ko00600 Sphingolipid metabolism
ko00531 Glycosaminoglycan degradation
ko00604 Glycosphingolipid biosynthesis - ganglio series
ko00511 Other glycan degradation
ko04142 Lysosome
ko04147 Exosome

ZFIN:

id description
ZDB-GENE-050410-9 Enables beta-galactosidase activity. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be active in vacuole. Human ortholog(s) of this gene implicated in GM1 gangliosidosis (multiple) and mucopolysaccharidosis IV (multiple). Orthologous to human GLB1 (galactosidase beta 1).

Ensembl:

ensembl_id ENSDARG00000036415

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00001137 True 2321 mRNA 0.48 16 52462068 52478746

Neighbor

gene id symbol gene type direction distance location
XLOC_000670 si:ch211-217k17.9 coding upstream 61408 52398205 ~ 52400660 (+)
XLOC_000669 si:ch211-217k17.8 coding upstream 65804 52392511 ~ 52396264 (+)
XLOC_000667 NA coding upstream 93870 52363402 ~ 52368198 (+)
XLOC_000668 NA coding upstream 94491 52365030 ~ 52367577 (+)
XLOC_000666 LO017718.1 coding upstream 98961 52353162 ~ 52363107 (+)
XLOC_000672 cldnd1b coding downstream 2586 52481332 ~ 52486995 (+)
XLOC_000673 BX323839.1 coding downstream 16297 52495043 ~ 52510756 (+)
XLOC_000674 tacr3l coding downstream 39430 52518176 ~ 52538517 (+)
XLOC_000675 abca1a coding downstream 81803 52560549 ~ 52628407 (+)
XLOC_000676 slc44a1a coding downstream 154110 52632856 ~ 52652163 (+)
XLOC_000665 NA non-coding upstream 115169 52345955 ~ 52346899 (+)
XLOC_000660 NA non-coding upstream 597303 51850561 ~ 51864765 (+)
XLOC_000681 NA non-coding downstream 328886 52807632 ~ 52807843 (+)
XLOC_000684 NA non-coding downstream 787654 53266400 ~ 53278288 (+)
XLOC_000686 NA non-coding downstream 841413 53320159 ~ 53320674 (+)
XLOC_000687 NA non-coding downstream 842185 53320931 ~ 53321338 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000302_00141480_00150149 GLB1 coding CI01000302 null 141029 ~ 150468 (-)