cylda (cyld,cylda,LOC107551493,LOC107550272)


Basic Information

Item Value
gene id cylda
gene name cyld,cylda,LOC107551493,LOC107550272
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_056705.1
NCBI id CM032074.1
chromosome length 41700998
location 21463050 ~ 21477450 (-)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>XM_043243776.1
ATGAGCTCTGCGCTATGGAGCCAGGAAAAGCCAGCAGGCAGTTTCCGGGACGACTGGCGCTTCTACATTGTGGTGAAGGAGTGCACTGTGGAAAAGCCGGGCCAGAAGACTCTGCGCATCCCACGCGGCAGCCTCGGCCAGGCCTGCCAGGAACGCAACAGCCTGGGTCGCACAATCCCGGCCAGCAAGGGTAAGCGCAGCCTACGCATCCTGGACCAGACCAATGTGGTGGTCAGCGTGGATGAACGGGACGTTATGGAGCTTGAGGAGAAGCTGGCAGAGCTGCTGTTCCCCATCACCAACTGCGAAGAGCGTTACAGCCTGCTGTACAACAGAGCGCGTCTGGACAGGGCCCGGGACATCAACTGCGGATCAAAAGTTCGAGTGCAGCTGAGGTCTGGCGACGTGCCCCTTCCAGGTGTGGTCCGATTTAAAGGAGCTTTGCTGCCAGACCGAGCTCTGAGCGGGATCTGGTTTGGTGTTGAATTACTGGAAGAGGGCCGGGGTCAAGGTTTCACCGAGGGCTCTTATCAGGGACAGCAGCTGTTTCGTTGCGAAGATGAATGCGGTGTCTTTGTTGCTCTGGATAAACTTGAGCTCTGGGAAGATGAGGTGGAACGTGTGACGCTGGAGGATAATGACCCGGAAGTGGAAGGCGAAGGACCGCCACTGGAGATCAACTCTCGAGTGTTGGTGCAGACACGGGATGGCCCGGAACGGGGCACTGTTATTTTCTGTGACTTACTGCCTGGCAATGAGAGCCTTGGATACTACGTTGGTGTTGATATGGACAATCCCATTGGAGACTGGGATGGGATCTTCGACGGCAAACAGCTGTGTAATTTTGCTAGTCTTGAACACACCCGTCTCGTTCCCATATGTGATGTGATGCCAGAATACTCCATGCAGGATCAGAGGCTGCCCAAAGTCTTTGCCTGCAGGGGCGGCAATGACAAACCTGGCAGCCAGAGCAAACCAAAGACCAAAGGGTTAGGCCTGCAGCCTGGCAGCAGGAGCAAGTCTGAGTTTTATTATACGCTAAATGGCAGCTCGGTTGATCACCCTGCTCAGTCCAAAGCCAAAAGCACATGGTACATAGATGAAGTTGGCGAGGACCCTGCCAAATCTCTGACGGACACGCCCCCAGACTTCAACCCAGGCTCGTCCCCTTCTCGAGCTCCGCCCACAAACTCATCGCTGTCCAATGATAACAAGTTCCACTCCCTGCCTTTTAGCTTGAGCCATAAAGTTGGCTCCAGTGGGAGCATGAGCCATGGCCCTCTCTCCCTGTCCGCGGGCTCAGTGATGGGGGAGCAGCAAGACGTCCTGCCACCTGCTACCACTCCTGTCCAGAGGCCTCCCTCGCCACCACAAGGTCAGCCGGGGTTAGAGGTCGGGTCATTGGTCGAGGTCAAGGAGAACCCACCACTTTGCGGGGTCATCCGCTGGGTTGGTCTACCTCCAGGACTACAAGAGCCACTAGCTGGGCTAGAGCTGgaggAGGAGTGTGTGGGCTGCACTGATGGAACGTTTAAAGGGATTCGTTATTTTACGTGTCCACCAAAGAAAGCTCTGTTTGTAAAGCTGAAGTGCTGCAGGCCTGACTCACGATTCCCATCCTTGCATCATTCACCCAACCCCATAGAACGATGCAACTCCATAGctTTTGGGGGTTACCTAAGTGAAGTAGTTAATGAGAACACTCCTCCTCGGACAGAAAATGATGGTTTAGAGGTGATGGTGGGGAAAAAGAAAGGAATACAAGGACATTACAATTCCTGCTATCTGGACTCTACTCTGTTctgTCTTTTCTCCTTTAGTTCTGTGTTGGATACGGTGCTCCTGAGGCCAAGATCTAAAACTGATGTAGAATATTACAAAGAGACACAAGACTTACTGCGGACAGAAATAGTCAACCCACTACGAATACATGGCTACGTGTGCGCCACTAAAATCATGAAACTTAGGAGGATATTGGAGAAAGTGGAGGCCGCGTCAGGATTCACCTCAGAAGAGAAAGATCCAGAGGAGTTCCTCAACATCCTTTTTCATCACATCCTGAGAGTCGATCCTCTTCTCAAACTTCGGTCTGCAGGGCAGAAGGTTCAGGACTGTTACTTCTATCAGATCTTTATGGATAAGAAAGATAAAGTGTTGGTGCCAACCAGTCAGCAACTTCTGGAGTGGTCCTTCATCAACAGTGATCTCAAATTTGCAGAGGCCCCTTCTTGCCTTATAATTCAGATGCCTCGTTTTGGGAAGGattttaagatgtttaataAGATTTTCCCTTCTCTGGAGCTTGACATCACAGACCTATTAGATGACACTCCTAGAGAATGTCGAATTTGTGGTGGCTTAGCTCTTTACGAGTGCAGAGAGTGCTATGAAGATTGCGATATCACACCAGGAAAGATCAAGCAATTCTGCGAAAAGTGCAATACACAGGTACATCTGCACCCGCGGCGTAAATCTCATCGGTGTGTTAAGTTATCTATACCTAAAGAGCTGCAGGAGTCTGTTTGGAGACAGGGATCTTACCCTCACCAGCAGATGGATCTGTTTGCCGTGCTTTGCATTGAGACGAGCCACTATGTCGCCTTTGTCAAATACGGATCAGCAGATTCAGCCTGGCTGTTCTTCGATAGTATGGCTGACCGTGACGGTGGTCAGAACGGGTTTAACATCCCACAGGTGTCCCCTTGCCCTGAAGTAGGGGCCTACCTGAAGATGACCCCAGAGGAACTCCACGCACTGGACCCCAAGAACATCCAGGGCTATGCACGCAGACTTCTCTGTGACGCCTATATGTGCATGTACCAGAGTCCCACCATGAGCCTCTATAAATAGAGAGGGAGAAATAAAGAAGGAAGGAAAGGTAGGAAAGGGAATGACCAAGAAGGAGAGAGATGAGGGAACGAGGGAACAGGAGGAAAAAAGTGCCCAGGATAACGCACTCCCACGACCGGTTGCCTCATCCTCTGTTCTGCATCTCTCTGTACATACTGCAGGGTAAATACGGTCATGAGAGCAAAGGCGAGATCAAGAGAACGAACGAAAAAGCCTATTTGCACTGTGTGAGagcatatgtgtttgtgtgtgtctgttgaaGTGTCATTGTTGTTTTCTCCGATTTGTGCCGTCTTGGGCTCAGCTCAGACTCTTTGAGTGTTCGGAGAGCGGTGTTTTTTTTGCACGGAGAGAATTCACAATCTTTCCAGCCCTCAGGTGTTTCGCAGACGCTCACTCACCTGAAGGCTTCACATTCGCCTCCTCCAGCCAGAATTGACCCCTCCAAACAACAACACGTTCTACCCCTGTAAATGAAGCCTTGGATGAATGACCCAAACAGGATGTTTCCCCTCTGTCTGAATTCTTCCATTCGTCATCAACCCATCTTAATGCACTGCAGCGTCCAGCATTAATTATAGTTCAGATGCACTGTGTGTAGTCCCTGTTTTTGCCTTTATATTTTGCTGTGAAGTCTTTGTCAGGTGTGTTCACAAACAGCAGAGCCCTTGACTGCCATGCACTGGTCCCAGATCAAGACGGAAGAAATGATTAAgcacacgttttttttttttcacatgaagAATTATATAATTgagctttttttgttaaaataggaattatttaatttgaattatggtttttataaatgtggaaattttaaatatagcaaaaaaaaaaaaaaactaacagctTCCCAGGCCATGCTTTCTAAATCATAAATTAGTGGTAAATGACTTCCTACGGATACGAGTCCAATATTATGATGATGAAATTCCAAAAGTGATTGTTTTGCAGTCAAGGACATGTTCATGTTATAAAGAAGTGATTCCAGTTCCTGTTTGTATATGACATGCTCTGGTTTGAATGTTCACGGCGGAGGCTGAATGGGCAGAAGCTGTTTCACGCTAAACTGCAGTGCTGTTGGCTAATTTGCGGTAACACTGTTCATCGAGATACTGGATTGATGTACTGCGCACATTTTTGCTATGGGTTATCGGATTGTTTACATGGCCTGGTTTAAACTGAAGGGTTATGGAAAGACACATGCATTGGGATTGTTTTTTAATCTCTGCTGATGTAACCGTACACTATGGGAGAGATTCTCCGTGAGCGGCTGTAATGGGAGAAAGGATGACGACTAGTGTACTTGTGTAAAATGAAGCCAGGTGGACTTTATTATCTCTGTGCTGTTCTCTTAAatgttaactaaattaaaacgcCATTTTGAAAACA
>XM_043243777.1
ATGAGCTCTGCGCTATGGAGCCAGGAAAAGCCAGCAGGCAGTTTCCGGGACGACTGGCGCTTCTACATTGTGGTGAAGGAGTGCACTGTGGAAAAGCCGGGCCAGAAGACTCTGCGCATCCCACGCGGCAGCCTCGGCCAGGCCTGCCAGGAACGCAACAGCCTGGGTCGCACAATCCCGGCCAGCAAGGGTAAGCGCAGCCTACGCATCCTGGACCAGACCAATGTGGTGGTCAGCGTGGATGAACGGGACGTTATGGAGCTTGAGGAGAAGCTGGCAGAGCTGCTGTTCCCCATCACCAACTGCGAAGAGCGTTACAGCCTGCTGTACAACAGAGCGCGTCTGGACAGGGCCCGGGACATCAACTGCGGATCAAAAGTTCGAGTGCAGCTGAGGTCTGGCGACGTGCCCCTTCCAGGTGTGGTCCGATTTAAAGGAGCTTTGCTGCCAGACCGAGCTCTGAGCGGGATCTGGTTTGGTGTTGAATTACTGGAAGAGGGCCGGGGTCAAGGTTTCACCGAGGGCTCTTATCAGGGACAGCAGCTGTTTCGTTGCGAAGATGAATGCGGTGTCTTTGTTGCTCTGGATAAACTTGAGCTCTGGGAAGATGAGGTGGAACGTGTGACGCTGGAGGATAATGACCCGGAAGTGGAAGGCGAAGGACCGCCACTGGAGATCAACTCTCGAGTGTTGGTGCAGACACGGGATGGCCCGGAACGGGGCACTGTTATTTTCTGTGACTTACTGCCTGGCAATGAGAGCCTTGGATACTACGTTGGTGTTGATATGGACAATCCCATTGGAGACTGGGATGGGATCTTCGACGGCAAACAGCTGTGTAATTTTGCTAGTCTTGAACACACCCGTCTCGTTCCCATATGTGATGTGATGCCAGAATACTCCATGCAGGATCAGAGGCTGCCCAAAGTCTTTGCCTGCAGGGGCGGCAATGACAAACCTGGCAGCCAGAGCAAACCAAAGACCAAAGTTGGCGAGGACCCTGCCAAATCTCTGACGGACACGCCCCCAGACTTCAACCCAGGCTCGTCCCCTTCTCGAGCTCCGCCCACAAACTCATCGCTGTCCAATGATAACAAGTTCCACTCCCTGCCTTTTAGCTTGAGCCATAAAGTTGGCTCCAGTGGGAGCATGAGCCATGGCCCTCTCTCCCTGTCCGCGGGCTCAGTGATGGGGGAGCAGCAAGACGTCCTGCCACCTGCTACCACTCCTGTCCAGAGGCCTCCCTCGCCACCACAAGGTCAGCCGGGGTTAGAGGTCGGGTCATTGGTCGAGGTCAAGGAGAACCCACCACTTTGCGGGGTCATCCGCTGGGTTGGTCTACCTCCAGGACTACAAGAGCCACTAGCTGGGCTAGAGCTGgaggAGGAGTGTGTGGGCTGCACTGATGGAACGTTTAAAGGGATTCGTTATTTTACGTGTCCACCAAAGAAAGCTCTGTTTGTAAAGCTGAAGTGCTGCAGGCCTGACTCACGATTCCCATCCTTGCATCATTCACCCAACCCCATAGAACGATGCAACTCCATAGctTTTGGGGGTTACCTAAGTGAAGTAGTTAATGAGAACACTCCTCCTCGGACAGAAAATGATGGTTTAGAGGTGATGGTGGGGAAAAAGAAAGGAATACAAGGACATTACAATTCCTGCTATCTGGACTCTACTCTGTTctgTCTTTTCTCCTTTAGTTCTGTGTTGGATACGGTGCTCCTGAGGCCAAGATCTAAAACTGATGTAGAATATTACAAAGAGACACAAGACTTACTGCGGACAGAAATAGTCAACCCACTACGAATACATGGCTACGTGTGCGCCACTAAAATCATGAAACTTAGGAGGATATTGGAGAAAGTGGAGGCCGCGTCAGGATTCACCTCAGAAGAGAAAGATCCAGAGGAGTTCCTCAACATCCTTTTTCATCACATCCTGAGAGTCGATCCTCTTCTCAAACTTCGGTCTGCAGGGCAGAAGGTTCAGGACTGTTACTTCTATCAGATCTTTATGGATAAGAAAGATAAAGTGTTGGTGCCAACCAGTCAGCAACTTCTGGAGTGGTCCTTCATCAACAGTGATCTCAAATTTGCAGAGGCCCCTTCTTGCCTTATAATTCAGATGCCTCGTTTTGGGAAGGattttaagatgtttaataAGATTTTCCCTTCTCTGGAGCTTGACATCACAGACCTATTAGATGACACTCCTAGAGAATGTCGAATTTGTGGTGGCTTAGCTCTTTACGAGTGCAGAGAGTGCTATGAAGATTGCGATATCACACCAGGAAAGATCAAGCAATTCTGCGAAAAGTGCAATACACAGGTACATCTGCACCCGCGGCGTAAATCTCATCGGTGTGTTAAGTTATCTATACCTAAAGAGCTGCAGGAGTCTGTTTGGAGACAGGGATCTTACCCTCACCAGCAGATGGATCTGTTTGCCGTGCTTTGCATTGAGACGAGCCACTATGTCGCCTTTGTCAAATACGGATCAGCAGATTCAGCCTGGCTGTTCTTCGATAGTATGGCTGACCGTGACGGTGGTCAGAACGGGTTTAACATCCCACAGGTGTCCCCTTGCCCTGAAGTAGGGGCCTACCTGAAGATGACCCCAGAGGAACTCCACGCACTGGACCCCAAGAACATCCAGGGCTATGCACGCAGACTTCTCTGTGACGCCTATATGTGCATGTACCAGAGTCCCACCATGAGCCTCTATAAATAGAGAGGGAGAAATAAAGAAGGAAGGAAAGGTAGGAAAGGGAATGACCAAGAAGGAGAGAGATGAGGGAACGAGGGAACAGGAGGAAAAAAGTGCCCAGGATAACGCACTCCCACGACCGGTTGCCTCATCCTCTGTTCTGCATCTCTCTGTACATACTGCAGGGTAAATACGGTCATGAGAGCAAAGGCGAGATCAAGAGAACGAACGAAAAAGCCTATTTGCACTGTGTGAGagcatatgtgtttgtgtgtgtctgttgaaGTGTCATTGTTGTTTTCTCCGATTTGTGCCGTCTTGGGCTCAGCTCAGACTCTTTGAGTGTTCGGAGAGCGGTGTTTTTTTTGCACGGAGAGAATTCACAATCTTTCCAGCCCTCAGGTGTTTCGCAGACGCTCACTCACCTGAAGGCTTCACATTCGCCTCCTCCAGCCAGAATTGACCCCTCCAAACAACAACACGTTCTACCCCTGTAAATGAAGCCTTGGATGAATGACCCAAACAGGATGTTTCCCCTCTGTCTGAATTCTTCCATTCGTCATCAACCCATCTTAATGCACTGCAGCGTCCAGCATTAATTATAGTTCAGATGCACTGTGTGTAGTCCCTGTTTTTGCCTTTATATTTTGCTGTGAAGTCTTTGTCAGGTGTGTTCACAAACAGCAGAGCCCTTGACTGCCATGCACTGGTCCCAGATCAAGACGGAAGAAATGATTAAgcacacgttttttttttttcacatgaagAATTATATAATTgagctttttttgttaaaataggaattatttaatttgaattatggtttttataaatgtggaaattttaaatatagcaaaaaaaaaaaaaaactaacagctTCCCAGGCCATGCTTTCTAAATCATAAATTAGTGGTAAATGACTTCCTACGGATACGAGTCCAATATTATGATGATGAAATTCCAAAAGTGATTGTTTTGCAGTCAAGGACATGTTCATGTTATAAAGAAGTGATTCCAGTTCCTGTTTGTATATGACATGCTCTGGTTTGAATGTTCACGGCGGAGGCTGAATGGGCAGAAGCTGTTTCACGCTAAACTGCAGTGCTGTTGGCTAATTTGCGGTAACACTGTTCATCGAGATACTGGATTGATGTACTGCGCACATTTTTGCTATGGGTTATCGGATTGTTTACATGGCCTGGTTTAAACTGAAGGGTTATGGAAAGACACATGCATTGGGATTGTTTTTTAATCTCTGCTGATGTAACCGTACACTATGGGAGAGATTCTCCGTGAGCGGCTGTAATGGGAGAAAGGATGACGACTAGTGTACTTGTGTAAAATGAAGCCAGGTGGACTTTATTATCTCTGTGCTGTTCTCTTAAatgttaactaaattaaaacgcCATTTTGAAAACA

Function

symbol description
cylda Enables Lys63-specific deubiquitinase activity. Acts upstream of or within central nervous system morphogenesis; cranial skeletal system development; and protein linear deubiquitination. Predicted to be located in several cellular components, including microtubule cytoskeleton; perinuclear region of cytoplasm; and plasma membrane. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in Brooke-Spiegler syndrome. Orthologous to human CYLD (CYLD lysine 63 deubiquitinase).
cyld Enables several functions, including deubiquitinase activity; proline-rich region binding activity; and zinc ion binding activity. Involved in several processes, including negative regulation of NF-kappaB transcription factor activity; protein deubiquitination; and regulation of signal transduction. Located in centrosome; cytosol; and spindle. Is extrinsic component of cytoplasmic side of plasma membrane. Colocalizes with cytoplasmic microtubule and midbody. Implicated in Brooke-Spiegler syndrome.

NR:

description
ubiquitin carboxyl-terminal hydrolase CYLD-like isoform X2

GO:

id name namespace
GO:0045087 innate immune response biological_process
GO:0021551 central nervous system morphogenesis biological_process
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway biological_process
GO:0070266 necroptotic process biological_process
GO:0070536 protein K63-linked deubiquitination biological_process
GO:0032088 negative regulation of NF-kappaB transcription factor activity biological_process
GO:0007346 regulation of mitotic cell cycle biological_process
GO:0006511 ubiquitin-dependent protein catabolic process biological_process
GO:0002181 cytoplasmic translation biological_process
GO:0005829 cytosol cellular_component
GO:0004843 thiol-dependent ubiquitin-specific protease activity molecular_function
GO:0003735 structural constituent of ribosome molecular_function

KEGG:

id description
K08601 CYLD, USLP2; ubiquitin carboxyl-terminal hydrolase CYLD

RNA

RNA id representative length rna type GC content exon number start site end site
XM_043243776.1 True 4245 mRNA 0.48 16 21463050 21477450
XM_043243777.1 False 4128 mRNA 0.48 15 21463050 21477450

Neighbor

gene id symbol gene type direction distance location
fto fto,LOC107696699,LOC107550283,LOC107657113,LOC107560393 coding downstream 513079 20834615 ~ 20949971 (-)
irx5a irx5a,LOC107713063,LOC107696697,LOC107564297,LOC107548945,LOC107657111,LOC107755130 coding downstream 832968 20626577 ~ 20630082 (-)
irx6a irx6a,LOC107563500,LOC107713056,LOC107696678,LOC107755049,LOC107657093 coding downstream 943761 20514693 ~ 20519289 (-)
mmp2 mmp2,LOC107713064,LOC107563472,LOC107755129,LOC107696695,LOC107548946 coding downstream 995887 20454260 ~ 20467163 (-)
lpcat2 lpcat2,LOC107713066,LOC107657092,LOC107755048,LOC107696694,LOC107548918 coding downstream 1009692 20442147 ~ 20453358 (-)
nod2 LOC107696706,LOC107750230,LOC107551491,LOC107657121,LOC107742770,LOC107550289 coding upstream 5657 21483107 ~ 21489525 (-)
nkd1 nkd1,LOC107696708,LOC107750231,LOC107742769,LOC107657122 coding upstream 21475 21498925 ~ 21523627 (-)
adcy7 LOC107551487,LOC107696709,LOC107750233,LOC107554606 coding upstream 98157 21575607 ~ 21614660 (-)
tent4b papd5,LOC107696711,LOC107657124,LOC107750234 coding upstream 137243 21614693 ~ 21631680 (-)
heatr3 heatr3,LOC107722414,LOC107696712,LOC107758777,LOC107657125 coding upstream 155237 21632687 ~ 21642595 (-)
G54971 NA non-coding downstream 6080 21456714 ~ 21456970 (-)
G54970 NA non-coding downstream 7183 21455565 ~ 21455867 (-)
G54969 NA non-coding downstream 7916 21454805 ~ 21455134 (-)
G54967 NA non-coding downstream 10012 21452808 ~ 21453038 (-)
G54925 LOC107740841,LOC107551473,LOC107696704,LOC107742772,LOC107657119 non-coding downstream 64175 21395486 ~ 21398875 (-)
G54976 NA non-coding upstream 19241 21496691 ~ 21497047 (-)
G54977 NA non-coding upstream 19763 21497213 ~ 21497500 (-)
G54978 NA non-coding upstream 20165 21497615 ~ 21497981 (-)
G55065 NA non-coding upstream 311300 21788750 ~ 21789393 (-)
G55189 NA non-coding upstream 605026 22082476 ~ 22082840 (-)
G54872 LOC107713054,LOC107550285,LOC107657115 other downstream 394675 21064933 ~ 21068375 (-)
G54687 NA other downstream 1182244 20278852 ~ 20280806 (-)
G54637 rfx7,LOC107689974,LOC107740453,LOC107563480,LOC107664392,LOC107755110,LOC107553094 other downstream 1461404 19995062 ~ 20001646 (-)
tex9 tex9 other downstream 1485769 19973261 ~ 19977281 (-)
map2k5 map2k5,LOC107755097,LOC107700484,LOC107663978 other downstream 1693645 19726122 ~ 19769405 (-)
cebpa cebpa,LOC107722391,LOC107696713,LOC107551484,LOC107733057,LOC107657126,LOC107580367 other upstream 175871 21653321 ~ 21753438 (-)
G55165 cd59,LOC107560108,LOC107736732,LOC107677235,LOC107722399,LOC107554602 other upstream 575346 22052796 ~ 22056245 (-)
si:dkey-23n7.10 si:dkey-23n7.10,LOC107560112,LOC107742582,LOC107554633,LOC107722376,LOC107703276 other upstream 625464 22102914 ~ 22105329 (-)
LOC122347949 LOC107560124,LOC107722378,LOC107656186,LOC107554594,LOC107742573 other upstream 954950 22432400 ~ 22440439 (-)
otog LOC107722353,LOC107656169,LOC107591037,LOC107703275,LOC107742581,LOC107554595 other upstream 966348 22443798 ~ 22488923 (-)

Expression


Co-expression Network