CI01000013_03793962_03821347 (CFTR)


Basic Information

Item Value
gene id CI01000013_03793962_03821347
gene name CFTR
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000013
NCBI id null
chromosome length 12551977
location 3793645 ~ 3821347 (-)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000013_03793962_03821347.mRNA
TACTGGCAGCGAATATCGACAATATCAGCGCTCGACTGTGCGCGCGGTGGCGGACAGCGCTCGCGAGCTTCATTCAACGGTGGACAAACCCTTTAATGAGAAAGGGTTTTAGGGAGAAACTGAGGCCATCTGATGTTTATCAAGCTCCCAGTCAAGATGCAGCAGATACTCTTGCAGAGCGTTTGGAAAAAGAATGGGACAGAGAAGTTGCATCTGGAAGGAAAAAACCCAGTCTACTGCGAGCCTTGGCACGATGCTTCATAAAACCTTTTCTGTTATTTGGCTTCCTCCTATATATAGGCGAGGCTACAAAAACAGTGCAGCCACAGCTTTTAGGGCGGGTCATTGCGTCATTTGACCCGGCCCATGAACCGGAGCGAGCCAATGGTTACTTTCTTGCCTTTGGTCTTGGCTTGCTATTCACTGCCCGCTTTCTCTTGCTCCAGCCTGCCATGTTTGGGCTGCACCGCCTGGGCATGCAGATCAGAATTGCACTCTTTAGCATAATCTATAAAAAGACCTTGAAACTTTCTAGCCGAGTCTTGGACAAGATCAGCACAGGTCAGCTGAGCCTGGGTATGGCCCATTTTGTATGGATATCACCATTGCAATGCATCCTGTGTACAGGGCTTATCTGGGAACTCATTGATGTCAATAGCTTCTGTGCACTTGCCGCCATCTCTTTACTGGGTGTCTTGCAGGCCTTTCTCTCACATAAAATGGGTCCCTACAAAGCACAAAAAGTGCTATTGACCAACAAACGGTTGGCTCTGACCTCAGAGATCATGGAGAACCTGCATTCGGTGAAGGCCTACGGCTGGGAGGAGATAATGGAGACCCTCATTAAGAACATCAGACAGGATGAGGTGAAGTTGACCAGGAAGATTGGCTCCCTGCGCTACTTCTACAGCTCTGCATACTTTTTCTCAGCTATCTTTGTGATTGTGGCTGCAGTGGTGCCCCATGCCCTCAGTCGTGGTATCAACCTGCGTCGCATATTCACCACTCTCTCCTACTGTATGGTGCTGCGGATGACTGTTACTCGACAACTGCCCGGCTCCATCCAGATGTGGTACGACACCATGCGGCTTATTTGGAAGATTGAAGAATTTCTTAGCAAGGAAGAATACAAGTTAATGGAGTACGATCTCAGCATCACAGAGCTGGAACTTAAAGATGTGACTGCTTCTTGGGATGAGGGTCCTGGTGAACTTCTAGAAAGGATAAAACAGGAGAACAAAGCTAATGGCCATCACAATGGAGATGCAGGCCTCTTCTTCACCAACCTTTATGTGACTCCTGTACTGAAAGACATCAGCTTGAACCTGAAGAAAGGAGAGATGTTGGCTGTTACCGGTTCTATGGGATCTGGGAAGAGCTCATTGTTGATGACCATCCTCGGGGAGCTGGTTCCCTCCTCTGGGAAGATCCGTCACAGCGGCCGAATCTCCTACTCCTCCCAAACAGCCTGGATCATGCCTGGAACCATCCGAGACAACATCCTTTTTGGCCTGACCTATGATGAGTATCGTTACAAGAGTGTGGTCAAAGCATGCCAGCTCGAGGAGGATCTGGCTGCTCTTCCTGAGAAGGATAAGACACCTATGGCAGAGGGGGGTTTAAACTTGAGTGGGGGTCAGAAGGCACGTGTAGCTCTGGCGAGGGCTGTTTACAGAGATGCTGATGTTTACCTGCTTGACGCACCATTTACTCACCTGGATATTGCAACAGAAAAAGAAATATTTGACAAATGTCTGTGTAAGCTGATGGCCTCCAAGACACGCATCTTGGTAACAAATAAGATTGAGCATTTGAAGCGGGCAGATAAGATCATACTGCTCCACAATGGTGAAAGTTTTTTCTACGGCACATTTTCAGAGCTTCAATCAGAGCGTCCTGATTTTAGCTCTTTGCTTCTGGGTTTGGAGGCCTATGACAATATCAGCGCAGAGCGCCGCTGCTCTATCCTCACAGAGACTCTCCACCGCGTCTCGGTGGATGAGAGCGCAGGCATGCGACCTGAACGCTCTTCTTATCGCCAGGTGGCCCCGCCCATGCCCAAGTACATAGATGAGAGAAAAGCTTCAGTGATCGTCAACCCTCTTGGAGCAGCTCGTAAGGCATCTTTCATTCAGGTACCAGAGGAAGAGGTCCGGAGGACATTACCTGAGCGGAAGTTTTCCCTGGTACCCGAGAACGAGCTAGTAGACGAATCCTTCATGGGAAGCGACGTGTATCATAACCACGGGGTGCATATGGCTGGTCAGAGAAGGCAGTCAGTGTTAGCCTTCATGACCAATGCACAAGGCCAGGGCCGTCGTGACCACCTTCAGTCCTCTTTCCGTAGACGGCTGTCCGTCGTGCCTCAGAGCGAACTGGCTTCTGAGCTGGACATCTACACTCGCCGCCTGTCGGACAGCACGTATGACATCCCCGGGGTCCTAGAAGAGGAGAACATTGAGGCATGTTTAGTTGATGAAATTGATGAAATAGAGGAGGCATTTGAAACGACAAAGTGGAACACATATGTCAGATATGTGTCAAATAATAAAAGTCTTCTTTATGTACTGATCTTCATCCTCATTGTTGCTGCAGCTGAGGTTGCAGGATCTGTAGCAGGGATCTTTCTGATAACTGATGAACTTTGGAGAGAAGAGCATCAGCGATTTGACCCAAACATGACAAAGCACTCCAACATTTCTTCACCTGGACAAAACTATGCAGTCATTGTGACCCCCACTAGCAGCTATTACATTCTCTACATCTATGTGGCCACATCAGAGAGCCTCCTCGCAATGGGATTTTTCCGGGGTCTTCCATTTGTGCACACTATGATCACAATCTCCAAGAAACTGCACCAGAAGATGCTGCGTGCTGTTCTCAGTGCACCCATGTCTGTGCTCAATACCATGAAGACAGGCCGAATCATGAATAGGTTCACCAAAGACATGGCCACAATAGATGACATGCTTCCTCTCCTCATGTTTGACTTTGTCCAGTTGTTAGATACGTCTTTGCAGTTGGCAAAGGGATTCCTGACGCACTCTGCATGCTGGCGTGTGGCTTGTTGCCAGGGACAAGAAGGCCAGTTTGACAGAGCCCTGATGGGAGCTCGGAGCCCCATTTTCTCCCACCTCATCATCTCGCTCAAGGGTTTGTGGACAATCAGGGCCTTTGAGCGGCAAGGTTACTTTGAGAACCTGTTCCACAAGACCCTCAACACCCACACTGCCACCTGGTTCCTCTATCTGTCGACCCTACGATGGTTTCTCTTCCGCGCCGACATCATCTTCGTGTTCTTTTTCACGTTGGCCGCCTGGATTGCGGTAGGAACCAACCAGGATAAACCGGGTGAGATTGGTATCGTCATATGCCTGGCAATGCTCATTCTAGGCACCTTCCAGTGGTGTGTTGCCACCAGCATTGCGGTAGATGGAATGATGCGTTCTGTTGACCGGGTGTTTAAGTTCATCGACCTACCGTCCGAGACACCCAAACCAGACAAAAGCAAAGGCTCGGATCTGATTATAGAGAATACCGATGCACAGGCTGACTCAAGCTGGCCTAACCGAGGTCAGATTGATGTGAGGAATTTAACAGTCAAATACACAGAAGGGGGTCACGCTGTTCTTAAGAACCTCTCCTTCGCTGTGGAGGGTGGACAGAGGGTGGGCATCTTGGGCCGAACAGGTTCTGGGAAGAGTTCTCTGTTCAATGCTCTTCTGAAGCTGGTTTACACAGATGGAGAAATCTCCATTGACGGGGTCAACTGGAACAAAATGCCACTTCAGAAGTGGAGGAAAGCCTTTGGCGTGGTGCCTCAGGTAACAGCGGTTCTGGGAACAGCTTCCATCCTCTCTCTTGATCATTTTTCAAGTTATATTTTTGTAAATGTCTCCTTCTACACCACACAGAAAGTCTTCATCTTTACGGGACCATTCCGCACGAACCTAGACCCTTATGGCTGCCATAGTGATGAGGAGCTGTGGCGGGTCACAGAAGAGGTCGGACTCAAGACACTGATTGAGCAGTTTCCAGACAAACTGGACTTCCAGCTGGAATACGGAGGTTATGTACTGAGTAACGGCCACAAACAGCTCATATGTCTGGCTCGCTCCATCCTCAGCAGAGCGCGGATCCTCCTCCTGGACGAGCCTAGTGCCCATCTTGATCCAATAACAATAAAGGTGTTAAAGAAGACATTGCGACAGTCTTTTTCCACATGCACTATATTACTGTCCGAGCACAAAGTGGAACCGCTGCTCGAGTGCCAGTCTTTCTTGATGATGGACAAGGGTCAGGTGAAGACCTACGATTCCATTCAGAAGCTGCTGAATGAAACCAGTCATCTAAAGCAGGCCATAAGTCCAGCCGAGCGCCTCAAACTCTTCCCTCGTCGGAATTCTAGCATGCGCACCCCTCAATCCAAACTAAGCTCTGTTACGCAGACACTACAGGAGGAGGCAGAGGACAATATCCAAGACACTCGTCTCTGAGCGTCTCAAACTGGACTTCATACGGACGCTTCCCCATCATCATGCTTTCTAAAGGTCTCCAAATGGTACATTATATTGGATGACCTATCTTCAGAACACATCTGACATTTGTTATGAAAAAGATATGTATTTTTCCTTAATGTCACAGGAGGTACTCAATATCCACTCACAATGAGACATTGTGAGGCCAGGAATAATTGAACACTGTAAAAAAAAATTTGTATAATGCAACTTTTGTGATTCATCTCTGTTTTGTTTTTTTTATCATATCAATTGTATTCTTTTCATATTTCTCTCTGAACGCTTAATTTATTAAA

Function

symbol description
cftr Enables ATP binding activity; ATP hydrolysis activity; and chloride channel activity. Acts upstream of or within several processes, including Kupffer's vesicle development; germ cell migration; and regulation of neutrophil chemotaxis. Located in apical plasma membrane. Is integral component of membrane. Is expressed in several structures, including Kupffer's vesicle; digestive system; forerunner cell group; head; and pleuroperitoneal region. Used to study cystic fibrosis and diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including alcoholic pancreatitis; allergic bronchopulmonary aspergillosis; bronchial disease (multiple); congenital bilateral absence of vas deferens (multiple); and lung disease (multiple). Orthologous to human CFTR (CF transmembrane conductance regulator).

GO:

id name namespace
GO:0016787 hydrolase activity molecular_function

KEGG:

id description
K05031 CFTR, ABCC7; cystic fibrosis transmembrane conductance regulator

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000013_03793962_03821347.mRNA True 4813 mRNA 0.48 26 3793645 3821347

Neighbor

gene id symbol gene type direction distance location
CI01000013_03726253_03740014 NA coding downstream 53237 3726117 ~ 3740408 (-)
CI01000013_03710900_03714487 NA coding downstream 79158 3708952 ~ 3714487 (-)
CI01000013_03588879_03592043 NA coding downstream 201602 3588767 ~ 3592043 (-)
CI01000013_03585420_03587386 ARPIN coding downstream 206259 3585252 ~ 3587386 (-)
CI01000013_03555460_03561041 KMT5B, SUV420H1 coding downstream 232052 3555379 ~ 3561593 (-)
CI01000013_03875165_03877327 NA coding upstream 53761 3875108 ~ 3877458 (-)
CI01000013_03879587_03884308 WEE2 coding upstream 57986 3879333 ~ 3884308 (-)
CI01000013_03897674_03902314 AGK coding upstream 75247 3896594 ~ 3902314 (-)
CI01000013_03911586_03916513 NA coding upstream 89262 3910609 ~ 3916634 (-)
CI01000013_03918402_03926395 RAPSN coding upstream 96825 3918172 ~ 3926395 (-)
G80365 NA non-coding downstream 7774 3785295 ~ 3785871 (-)
G80364 NA non-coding downstream 10963 3782252 ~ 3782682 (-)
G80326 NA non-coding downstream 61848 3731598 ~ 3731797 (-)
G80325 NA non-coding downstream 64253 3729152 ~ 3729392 (-)
G80324 NA non-coding downstream 66258 3726950 ~ 3727387 (-)
G80377 NA non-coding upstream 1971 3823318 ~ 3835856 (-)
G80382 NA non-coding upstream 16567 3837914 ~ 3840134 (-)
G80402 NA non-coding upstream 125504 3946851 ~ 3948820 (-)
G80404 NA non-coding upstream 138496 3959843 ~ 3961577 (-)
G80407 NA non-coding upstream 140791 3962138 ~ 3962379 (-)
G80271 NA other downstream 70038 3719433 ~ 3723607 (-)
G80262 NA other downstream 226108 3565171 ~ 3567537 (-)
G79690 NA other downstream 978253 2813247 ~ 2815392 (-)
G78296 NA other downstream 3766748 26528 ~ 26897 (-)
G80399 NA other upstream 82720 3904067 ~ 3906240 (-)
G80443 NA other upstream 243595 4064942 ~ 4066017 (-)
CI01000013_04561253_04567647 MAP2K1 other upstream 735521 4560340 ~ 4567647 (-)
G81032 NA other upstream 927462 4748809 ~ 4750561 (-)
G81547 NA other upstream 1918179 5739526 ~ 5744038 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_012778 cftr coding NC_007129.7 CM002902.2 20677090 ~ 20722810 (+)