CI01000014_00672822_00683285 (PPP2CA, PPP2CA.L, PPP2CB)


Basic Information

Item Value
gene id CI01000014_00672822_00683285
gene name PPP2CA, PPP2CA.L, PPP2CB
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000014
NCBI id null
chromosome length 1317303
location 672235 ~ 683862 (-)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000014_00672822_00683285.mRNA
AGTATCTTACTTTCTCTATTACTGTTCACCCCAAAGTTTGGATCAAAATATAATGTTTCATAATTTCTGAATCTGAAAACACGCCTCTTTTTTTCTGTCAACACTGACATTGAGCAATTATGAATGTAATATTTATCAACAATTCTAAATAAAATAGATACATAATTATAAAACAATAACATATCTGCACATTTTATACACACACACAAAAAAATAAAATAAAAATAATATAACCGTTGACGTGTTAATGAGATCCTATTGCAGTAAAGGAAAACGCCCAACGACGCATTTGGCAACCAATCAGAGCGGAGTATCAGCTGTGAGCGTCCAATTAGCGACGAGCCGGTTGTCGGTGTTTGATGTGAGGAAGGCTGAAGTGAAAACAACTGTGGGTCAGGGTGGGACTCTGAAGGCCGTCGGCTTCTCATTTCCTCACAGGATTCCCTTCTTTAATTACTCCAAGATCCCTGGCCACATGTACGTTTTAAAGTAATCAGTCGATTTCGGGTGGATATTCGTGGAAAGCTGGGCGAAGGTAGATCAGAAATCTGTGAAAATCGAGTGAAAAAAAGCAGACATGGACGAAAAGGCGTTTACGAAAGAGCTGGATCAATGGATCGAACAGCTGAATGAATGCAAACAGCTCTCAGAAAGCCAAGTCAAGAGCCTCTGTGAGAAGGCTAAAGAAATCCTGACCAAGGAGTCTAATGTGCAGGAAGTGAGATGTCCGGTCACTGTGTGTGGAGATGTTCACGGCCAGTTTCATGACCTCATGGAGCTCTTCAGAATCGGAGGAAAGTCACCAGACACGAACTACTTGTTCATGGGAGATTATGTTGACCGAGGCTATTATTCTGTGGAAACAGTCACACTGCTCGTCGCCCTCAAGGTTAGGTACCGTGAACGCATTACAATACTTCGAGGGAACCACGAAAGCAGACAGATCACACAAGTGTACGGCTTTTATGATGAGTGCTTACGGAAATACGGCAATGCTAATGTTTGGAAATACTTCACAGACCTCTTCGATTACCTTCCCCTTACTGCCTTGGTAGATGGTCAGATATTCTGTCTTCATGGAGGATTGTCACCGTCCATAGACACTCTTGATCACATCAGAGCGCTGGATCGTTTACAGGAAGTTCCTCACGAGGGACCCATGTGTGATTTATTGTGGTCTGATCCGGATGACCGTGGAGGTTGGGGTATTTCTCCTAGAGGTGCAGGCTACACTTTTGGGCAGGACATATCTGAGACATTCAACCATGCAAATGGCCTTACGCTGGTCTCTAGAGCTCACCAGCTAGTGATGGAGGGCTACAACTGGTGCCATGATCGCAATGTGGTAACGATTTTCAGCGCACCCAACTACTGTTACCGGTGTGGTAATCAGGCAGCCATCATGGAGCTTGATGACACCCTGAAGTACTCATTCCTGCAGTTTGACCCCGCACCGCGCAGAGGAGAGCCGCACGTCACTCGCCGTACCCCCGACTACTTCCTGTGAATCTCTCTCTCTGCACAGTATTGCCATGATATAATAATCTTCATTCAGTTTAAAATAAGAGGAGAGGAATGGGCAACAGTATATAAAAAAGATTAAAGAGAAAACTGATCCAGTGAGAAATGTCTGTGGACCAAAAGGTGTGTGCCATATCCAAACCGATCCGGCTTCAGTCCGACACCACGACCATGAGATATCAGCTCCGTTCCCGTCTGCTCTTGCTTCTGTCCTCCGGTCTCTAGATGAATACAGTCAACAGGCTGTGAAACCCTTCTGAACCCTCTGTGTGTACTTTCTTCTTTTTTTTATGTCTGTTTGCACTTTTTTCAACTGAACGACAGCTAACACATGTCAGTTTTACAGTTTATTTCCCCTTTTTTTTCCATGTGGTGAGGGAGGAATGAGATTAGATGCTTCTGTATCTCAACCACCAATATCTAGAGGATAATCTTTCCTACAGTGAAAACATGTTAAACAAATGCCAACTACGTGATATGTGGCAGACTAAGATGGCATGCCATCATAGGAATGCTGGAATAGCTTCATATGATGGTTTGTGTCTGTATAAAGGGTACCAGTTCAACAATAAA

Function

symbol description
ppp2cb Predicted to enable protein serine phosphatase activity and protein threonine phosphatase activity. Orthologous to human PPP2CB (protein phosphatase 2 catalytic subunit beta).
ppp2ca Enables protein heterodimerization activity and protein serine/threonine phosphatase activity. Involved in negative regulation of epithelial to mesenchymal transition; peptidyl-threonine dephosphorylation; and positive regulation of protein serine/threonine kinase activity. Located in membrane raft. Part of protein phosphatase type 2A complex. Biomarker of Parkinson's disease; congestive heart failure; and prostate cancer.

GO:

id name namespace
GO:0006470 protein dephosphorylation biological_process

KEGG:

id description
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000014_00672822_00683285.mRNA True 2094 mRNA 0.44 7 672235 683862

Neighbor

gene id symbol gene type direction distance location
CI01000014_00660099_00665508 SKP1.S, BRAFLDRAFT_124598, SKP1A, SKP1 coding downstream 6537 659990 ~ 665698 (-)
CI01000014_00466896_00506088 RAPGEF6 coding downstream 166147 466212 ~ 506088 (-)
CI01000014_00094545_00097426 NA coding downstream 574809 94176 ~ 97426 (-)
CI01000014_00058937_00066714 CCT6A.S, CCT6A coding downstream 605521 58727 ~ 66714 (-)
CI01000014_00046124_00047713 NA coding downstream 624522 45107 ~ 47713 (-)
CI01000014_00696364_00697192 NA coding upstream 12502 696364 ~ 697192 (-)
CI01000014_00753559_00756594 NA coding upstream 69622 753484 ~ 756594 (-)
CI01000014_00775503_00794925 FNIP1 coding upstream 91016 774878 ~ 794925 (-)
CI01000014_00821373_00846608 NA coding upstream 137312 821174 ~ 848060 (-)
CI01000014_00852874_00874645 NA coding upstream 168653 852515 ~ 874736 (-)
G86411 NA non-coding downstream 129359 542577 ~ 542876 (-)
G86408 NA non-coding downstream 135381 536609 ~ 536854 (-)
G86402 NA non-coding downstream 234462 437539 ~ 437773 (-)
G86386 NA non-coding downstream 249726 422128 ~ 422509 (-)
G86385 NA non-coding downstream 250263 421616 ~ 421972 (-)
G86470 NA non-coding upstream 63225 747087 ~ 747325 (-)
G86472 NA non-coding upstream 64184 748046 ~ 748344 (-)
G86473 NA non-coding upstream 64634 748496 ~ 748847 (-)
G86474 NA non-coding upstream 65215 749077 ~ 749578 (-)
G86482 NA non-coding upstream 74101 757963 ~ 758187 (-)
G86530 NA other upstream 301356 985218 ~ 985744 (-)
G86532 NA other upstream 303682 987544 ~ 988027 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_019885 PPP2CA coding NC_007132.7 CM002905.2 45351660 ~ 45363956 (-)
bowfin (Amia calva) AMCG00011269 ppp2ca,LOC107603261,LOC107692973,LOC107728270 coding CM030133.1 CM030133.1 16133452 ~ 16141505 (+)