CI01000016_04193887_04198494 (TUBB4B, TUBB4A, TUBB5, TUBB, TBB5, TUBB2B)


Basic Information

Item Value
gene id CI01000016_04193887_04198494
gene name TUBB4B, TUBB4A, TUBB5, TUBB, TBB5, TUBB2B
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000016
NCBI id null
chromosome length 12175457
location 4193887 ~ 4199380 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000016_04193887_04198494.mRNA
ATGAGGGAGATTGTTCACATCCAGGCCGGCCAGTGCGGAAACCAAATCGGTGCCAAGACTCTAACCATAAATCTCTTTGTCTGTAAATCAGAGATGTGGGTGAAGGGATTCACTGAGGGAAAGGGGGATATTGACCGCTGTGAATCAATGGTCAACCGGAGGATGATGGGAAGGTTCTGGGAGGTCATTAGTGATGAACATGGAATCGACCCAACAGGAACCTATCATGGAGACAGTGACCTGCAGCTGGACAGAATTAGTGTCTACTACAATGAAGCTACAGGAGGTAAATATGTGCCAAGAGCTATTCTAGTGGATCTCGAGCCTGGCACCATGGACTCTGTGCGTTCAGGACCCTTCGGACAGATCTTCAGACCAGACAACTTTGTATTTGGCCAGAGCGGTGCTGGTAATAACTGGGCTAAGGGCCACTACACAGAGGGGGCGGAGCTTGTGGATTCCGTTCTGGATGTGGTCCGCAAGGAGTCCGAGAGCTGTGACTGCCTACAGGGCTTCCAGCTCACTCACTCCTTGGGCGGAGGAACCGGCTCCGGCATGGGCACCCTATTGATCAGCAAAATCCGTGAAGAGTACCCTGACCGCATCATGAACACCTTCAGCGTGGTGCCTTCCCCAAAAGTCTCTGACACCGTAGTGGAGCCTTACAACGCCACGCTGTCAGTCCATCAGCTGGTGGAGAACACAGACGAAACCTATTGCATAGACAATGAAGCCTTATATGATATCTGTTTCCGCACCCTCAAACTCACCACTCCCACATATGGTGACCTCAACCATCTGGTCTCTGCCACTATGAGCGGTGTCACCACCTGCCTGCGCTTCCCCGGCCAGCTAAATGCTGATCTGCGGAAGTTAGCAGTCAACATGGTGCCCTTCCCCCGTCTCCACTTCTTCATGCCCGGTTTCGCCCCTCTGACCAGCCGAGGCAGCCAGCAGTACCGCGCCCTCACCGTGCCTGAGCTCACGCAGCAAGTGTTCGATGCCAAGAACATGATGGCAGCCTGCGATCCCAGACACGGACGCTACCTGACCGTCGCTGCTGTGTTCCGTGGCCGCATGTCCATGAAGGAAGTTGACGAGCAGATGTTGAATGTCCAGAACAAGAACAGCAGCTACTTCGTGGAATGGATCCCCAACAACGTCAAAACCGCAGTGTGCGACATTCCACCTAGAGGTCTCAAAATGGCCGTCACCTTCATCGGCAACAGCACAGCCATCCAGGAGCTGTTCAAGCGCATCTCCGAGCAGTTCACGGCCATGTTCAGGCGTAAGGCTTTCCTGCATTGGTACACGGGAGAGGGGATGGACGAGATGGAGTTCACAGAGGCGGAGAGCAACATGAATGATCTGGTGTCCGAGTACCAGCAGTACCAGGACGCCACCGCCGAAGAAGAGGGCGAGTTTGAGGAAGAGGCAGAAGACGATGCTTAAGAAGGAAATGAAAGGGGAGGCGGTAGTGTGTTCAAGTTTGAGTAAATGTAGCAAAACGTACATGGAAACACTTTTAGTGTCTCAAGTAGAAATTAGCACTAGAAAAATGGGGCCAAAAATAACCAGAGGAAGGCAGAAAGAATGTTCTTAAACACAGAATAGGTGGATGACAGTGTTTACAATTACAAATTGCTCACTTTTTGTGTACTTCTTAACTATTCTGATGGTCAGTTGCTCTCTGTACAGAACAGGGAAGAAAAAATGGCAAACATCCAGTTAGAATCAATGTTATAAATGGATAGATGGTGGGGTCAGGGAGGACAGTAACATCTCATTATTCTTTATTTTAACATTTGCTTCTTTTTGTCTGCATATAACTGAAGTAAAAATATTATTATGGTGTTTTTTTGTGTTTTCTTTGTTACTATTGCACTAGAACAGGGCAACTCTGTGAGATAATGGCACTTCAACATGACCTCAATGGGTCTGATTGCAGTATTTAAAGAAATGTTTTGAAGAGAAAAGTATGTTGTGTGAAAGATGAAGGAAAAGAAAAGGACTGAAAGAAAGACAGAATAACCGGTTCAGAATAACAGGGTTATTTATTCATAACCTCGCTTGGACGCCAGCCAACGTCTACAGGAGGACAGAAATCGATTTATGACATGGACGATACAGGAAAGTATTATGCAGAAGGAAAGACAGGAGTTTTAGCATGTTGAATTGATTGTCGGTGCAATTTTTAAATTCATGGACTCTGTTATGTCTCATTTCTGAGCCCATACATTTAAGTGTTACTACATATTGTTAATTACATATTTTAAGTCTTTTGATGTTCCTTGATTGTCCCTGTGTGGAAAAAACTGAGCCTCTGGAGAAAACCAAA

Function

symbol description
tubb4b Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Acts upstream of or within cilium assembly. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm and microtubule. Is expressed in brain. Human ortholog(s) of this gene implicated in Leber congenital amaurosis with early-onset deafness; hypomyelinating leukodystrophy 6; and torsion dystonia 4. Orthologous to several human genes including TUBB4B (tubulin beta 4B class IVb).
tubb5 Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Acts upstream of or within fin regeneration. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm and microtubule. Is expressed in midbrain hindbrain boundary neural keel; nervous system; optic vesicle; and spinal cord neural tube. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 6 and congenital symmetric circumferential skin creases 1. Orthologous to human TUBB (tubulin beta class I).
tubb2b Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to act upstream of or within microtubule-based process. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm and microtubule. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 7. Orthologous to human TUBB2B (tubulin beta 2B class IIb).
tubb4a Enables calcium ion binding activity. Involved in negative regulation of microtubule polymerization. Located in axoneme and microtubule. Implicated in hypomyelinating leukodystrophy 6 and torsion dystonia 4.
tubb Enables MHC class I protein binding activity and ubiquitin protein ligase binding activity. Involved in cellular process. Located in several cellular components, including cytoplasmic ribonucleoprotein granule; microtubule; and nuclear envelope lumen. Implicated in complex cortical dysplasia with other brain malformations 6 and congenital symmetric circumferential skin creases 1.

GO:

id name namespace
GO:0005200 structural constituent of cytoskeleton molecular_function

KEGG:

id description
K07375 TUBB; tubulin beta

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000016_04193887_04198494.mRNA True 2338 mRNA 0.47 6 4193887 4199380

Neighbor

gene id symbol gene type direction distance location
CI01000016_04156457_04176927 DDR1 coding upstream 16252 4156457 ~ 4177635 (+)
CI01000016_04104194_04120918 GNL1, ZNF384 coding upstream 72379 4103904 ~ 4121508 (+)
CI01000016_04062946_04083356 CSN7A, COPS7A coding upstream 110327 4062703 ~ 4083560 (+)
CI01000016_04054332_04058529 NA coding upstream 135189 4054021 ~ 4058698 (+)
CI01000016_04038553_04043435 NA coding upstream 150313 4038504 ~ 4043574 (+)
CI01000016_04204029_04208418 MDC1 coding downstream 4649 4204029 ~ 4208715 (+)
CI01000016_04212233_04219411 NA coding downstream 12417 4211797 ~ 4219769 (+)
CI01000016_04234275_04238405 INO80E coding downstream 34895 4234275 ~ 4238501 (+)
CI01000016_04246693_04261518 VARS2, VARS coding downstream 47313 4246693 ~ 4261629 (+)
CI01000016_04321053_04331396 NA coding downstream 121673 4321053 ~ 4332239 (+)
G95445 NA non-coding upstream 11946 4077383 ~ 4181941 (+)
G95626 NA non-coding upstream 192787 4000781 ~ 4001100 (+)
G95623 NA non-coding upstream 199806 3993806 ~ 3994081 (+)
G95622 NA non-coding upstream 200413 3993274 ~ 3993474 (+)
G95621 NA non-coding upstream 200626 3993037 ~ 3993261 (+)
G95649 NA non-coding downstream 172201 4371581 ~ 4371833 (+)
G95650 NA non-coding downstream 173606 4372986 ~ 4373220 (+)
G95659 NA non-coding downstream 218508 4417888 ~ 4418614 (+)
CI01000016_04428669_04441464 DEDD1 non-coding downstream 240178 4428669 ~ 4441464 (+)
G95673 NA non-coding downstream 317496 4516876 ~ 4517094 (+)
G95439 NA other upstream 330030 3862175 ~ 3862305 (+)
G93406 NA other upstream 3266355 905400 ~ 927532 (+)
G95648 NA other downstream 73256 4272636 ~ 4273905 (+)
CI01000016_04829592_04837305 NA other downstream 635178 4829592 ~ 4837457 (+)
G95792 NA other downstream 1020500 5219880 ~ 5225941 (+)
CI01000016_05405791_05407797 AICDA other downstream 1206489 5405791 ~ 5407963 (+)
G96389 NA other downstream 2961261 7160641 ~ 7161290 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_009714 tubb5 coding NC_007127.7 CM002900.2 10318893 ~ 10327620 (+)