CI01000026_03429002_03432390 (CYP2R1)


Basic Information

Item Value
gene id CI01000026_03429002_03432390
gene name CYP2R1
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000026
NCBI id null
chromosome length 17172400
location 3429002 ~ 3433060 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000026_03429002_03432390.mRNA
CTCTTAAAGCAGCGGAGACCCCGAGGGTTTCCCCCTGGACCGACACCTTTACCCATGATAGGGAATATTCTGTCCCTAGCCACCGAGCCTCACGTCTACATGAAGAGGCAGAGTGATATCCACGGACAGATTTTCAGTCTAGACCTGGGAGGAATCTCGACTGTTATTCTAAATGGTTATGATGCCATTAAAGAGTGCCTGTATCACCAAAGTGAGGTTTTTGCTGACCGTCCATCCCTCCCTTTATTTCAAAAGATGACAAAAATGGGAGGACTTCTGAACTGCAAATATGGTCGAGGCTGGATTGAACACCACAAACTGGCTGTGAACTGCTTCCGCTACTTTGGCAGTGGTCAGCGAATGTTTGAGAGGATTTCTGAGGAGTGCCTGTTTTTTCTGGATGCCATTGACCAGCACCAGGGGAAGCCCTTTAACCCTAAGCATCTCGTTACCAATGCCGTCTCCAACATCACCAACCTCATTATCTTCGGGCAGCGTTTCACCTATGATGATGGTGATTTTCAGCACATGATTGAGATCTTCAGTGAGAATGTGGAGCTGGCAGCCAGTGGCTGGGCTTTCTTGTACAACGCCTTCCCCTGGATGGAGTACCTGCCATTCGGGAAGCATCAAAAGCTGTTCCGCAATGCCAACAAGGTGTACGACTTCCTTCTGCAAATCATCAAGCGCTTCTCACAGGGCAGGATTCCCCAGTCGCCGCAACATTACATTGATGCCTACTTGGACGAAATGGAGCAGAGCGCCACCGATAAAGCTACATCTTTCTCTCAAGACAATCTCATTTTCTCTGTTGGAGAACTTATCATTGCGGGCACAGAGACCACCACAAATTGTCTGCGCTGGGCTATGTTATACATGGCTCTATATCCCAGGATACAAGAAAAGGTCCAAATGGAGATCGATTGCATCCTGAATGGCAGACCACCTGCTCTTGAAGACAAGCAGAGGATGCCATATGTGGAGGCAGTGCTGCATGAAGTCCTGCGCCTTTGCAATGTCGTCCCACTGGGCATCTTTCGCGCTACGTCTCAAGACGCGGTGGTGCGTGGCTACACTATCCCCAGGGGTACCATGGTCATCACTAACTTGTACTCGGTGCACTTTGACGAGAAGTACTGGAGCGACCCATCCATCTTCTGCCCAGAGCGGTTCCTTGACTGTAATGGCAAATTTGTCCGGCATGAAGCATTTCTCCCCTTCTCAATAGGTAAGCGGCACTGTCTGGGAGAGCAGTTGGCCAGACTGGAGATGTTCTTATTCTTCACCACATTGCTCCAGAGGTTTCACCTTCAGTTCCCAGAAGGCTTTATTCCAAGTCTCTCTCCAAAACTGGGCATGACCCTTCAGCCTCGGCCGTACGCCATATGTGCCATCAGGAGACAGCAGTAAAACTTCCCCCGTGAGCTCTTGAACACATGCACTCATGTCAGGGGATACTACCAAGAAACACAAATGTCAGAGAAGTTCTCCATCTTAAATTCCATCAGGTTTTCAACAGGGAATTTTGACCTCTGATATTGACTTGTTAAATTCTCTGAACGTGTCCTCTAGAGTTTCACAGAACCCAGCCTGAGTGATAAGAGTACTGTTACAGAACACATGGCGTGGAGAGCAAAGAATGAGCACATGTGTGTTACCAAACAAGAACGTACATGAGGGTATCAGGATATAGTGTAGCCTGTATCTTTGATAACTAGTCGAAAAAGTGTACTGTGGAACCAACCGAACATTGTGCTTGTCAATATGAGAAGAGCTATTGTGTCAATGATTGACAGGGTTTACCTCTATGATGGTTTGGAGGTCTGTCTTCATGACTCCTGTTGGTTTAATGCCATATAGCAGTTCTGCAATAATAACGGCCCTTTCCCTAGTTTATCTCAGTGGAAAGAGATTATCCAGAAACTTGAGCTGCAATATTTCTGAGGAAAAAATGGTGCTATTGTGAAAAGCTGACTCCAATATACGTTTTTTAGTACAATATCAGTTTTGCTTTACTTTGAATTTTAATAAGTTTTTGTGCTTATGATAAAATGAAACAAAACCTGACAAACTTGTATAA

Function

symbol description
cyp2r1 Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Acts upstream of or within cellular response to vitamin D; hematopoietic stem cell proliferation; and vitamin D3 metabolic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Is expressed in liver; muscle; ovary; and visceral fat. Used to study vitamin D-dependent rickets type 1B. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus and vitamin D-dependent rickets type 1B. Orthologous to human CYP2R1 (cytochrome P450 family 2 subfamily R member 1).

GO:

id name namespace
GO:0004497 monooxygenase activity molecular_function

KEGG:

id description
K07419 CYP2R1; vitamin D 25-hydroxylase

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000026_03429002_03432390.mRNA True 2080 mRNA 0.46 5 3429002 3433060

Neighbor

gene id symbol gene type direction distance location
CI01000026_03279718_03281541 NA coding upstream 146586 3278858 ~ 3282416 (+)
CI01000026_03163505_03268602 SOX6 coding upstream 160400 3163505 ~ 3268602 (+)
CI01000026_03037832_03085312 NA coding upstream 343476 3037832 ~ 3085526 (+)
CI01000026_02976981_02977701 NA coding upstream 449989 2976441 ~ 2979013 (+)
CI01000026_02947832_02950047 RPS13, RPS13.L, RS13 coding upstream 478935 2947689 ~ 2950067 (+)
CI01000026_03497917_03504607 COPB1, COPB coding downstream 64857 3497917 ~ 3504607 (+)
CI01000026_03554511_03560631 RRAS2, RRAS2.L coding downstream 121451 3554511 ~ 3560915 (+)
CI01000026_03664983_03686916 TUB coding downstream 231923 3664983 ~ 3687346 (+)
CI01000026_03725294_03727306 NA coding downstream 292234 3725294 ~ 3727411 (+)
CI01000026_04062224_04065987 SLC7A6OS coding downstream 629164 4062224 ~ 4066428 (+)
G127916 NA non-coding upstream 82819 3345969 ~ 3346183 (+)
G127899 NA non-coding upstream 109266 3319474 ~ 3319736 (+)
G127815 NA non-coding upstream 154355 3274275 ~ 3274647 (+)
G127856 NA non-coding upstream 470412 2958334 ~ 2958590 (+)
G127782 NA non-coding downstream 167605 3600665 ~ 3601199 (+)
G127762 NA non-coding downstream 237428 3670488 ~ 3670881 (+)
G128039 NA non-coding downstream 514761 3947821 ~ 3948061 (+)
G127754 NA non-coding downstream 565404 3998464 ~ 3999564 (+)
G127743 NA non-coding downstream 601797 4034857 ~ 4036844 (+)
CI01000026_02659356_02660297 NA other upstream 768173 2658605 ~ 2660829 (+)
G127519 NA other upstream 1001996 2393683 ~ 2427006 (+)
G127531 NA other upstream 1116867 2309322 ~ 2312135 (+)
G127500 NA other upstream 1482563 1931183 ~ 1946439 (+)
CI01000026_00776867_00777588 NEDD8, BRAFLDRAFT_284180, NEDD8L, NEDD8.S other upstream 2651205 776757 ~ 777830 (+)
G127979 NA other downstream 319491 3752551 ~ 3762986 (+)
CI01000026_04327206_04331151 DOK4, DOK5 other downstream 854813 4327206 ~ 4332085 (+)
G128137 NA other downstream 997502 4430562 ~ 4431201 (+)
CI01000026_04556074_04556964 FOXB1B, FOXB1, FOXB1A other downstream 1122716 4555776 ~ 4557613 (+)
G128585 NA other downstream 2516753 5949813 ~ 5950122 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_033761 cyp2r1 coding NC_007118.7 CM002891.2 27455321 ~ 27697234 (+)