XLOC_008865 (apoa1b)


Basic Information

Item Value
gene id XLOC_008865
gene name apoa1b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007126.7
NCBI id CM002899.2
chromosome length 48040578
location 102925 ~ 108414 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00017527
ATCCATGATGAGGTTCGTAGCCCTCGCCCTCACCGTATTCCTGGCAGGTTGCCAGGCCCGGTTCCTGCAGGACGAGCCCCCATCGCAGCTGGAGCATGTGAAGTCTGCACTGCAGGTTTATGCAGATCATCTGAAGCAGGCCGCACACAAGTCCCTCACTCACCTCGACGACACCGAGTTCAAAGATTACAAAGTCTTCCTGGGCCAGTCCATCGACAACCTCCATTCCCACTTCCAGAACTTCTTCCAGGTCATCACGCCTCTGGGCTCTCAGGTGATGGATGCCACCAACCCCATCCGCGAGAAGCTGAACAAGGACATGGAGGACCTGCGCAAGGACATCGAGCCCAAGCGCGAGGAGCTCAGAGCCGTGCTGGAGAAACACTTCAATGAGTACAGGGATGAGCTGAAGCCCTTCATGGACGACTACCTGGTCAAGCAGCGTCAGCACATGGAGGAGGTCAGGGCCAAGCTGGAGCCTGTGGTCCTCAGCCTGAAGGAGAAGATCCCACCCAACTGGGAGGAGACCAAGTCCAAGCTGATGCCCATCCTGGAGGCCATCCGAGGCAAGGTGGCGGAGAACGTGCAGGAGCTGAGGACCATGCTGGAGCCCTACGTCCAGGAGTACAAGGACCAGATGGAGAAGGGAGCCTTGGAGTTCAGAGAGAAGGTGAAGTCTGGAGAACTGAGGAAAGAGCTGACCGAGCTGGGAGAGCAGGTGAAGCCACACTTCGAGGGCATCTTCAAGGCCCTCCAGAAGTTCGCCAGCAAGGAGTAAAGCGACCGTTTTGTACACCATCCCATCCTCCCTTATCCACGGCTTCTCTCAGAGCATAGCTgatcttttctctctctctctctctctctctctctcacacaaacacacacacacacacacacacacacacactgatacaggCCCGTAGTACACTCATATGCACTTTGtacacatgaccacacacacacagacacacacatgcaggacTTGCGTTCTCTCTAATGGGCAAACTCAGCTAAGAACACTGAATCCTGTTCATTCAAAAACGCCTAGCAAAATccctttgttaagctgctttgtgTTAAAAACTGATGTTCAATGTTCAAtccaatgaaataataaaaataacaaactttCATACTACTCTTGTTCCGTGTCTGCATGTGTCTCATTAGTGAGGTGTGTTTGTTGTACATGTATGGGGATTGTATTtaagcgatatatatatataggaaatatgaatattattgtttttaatggaCAAATGCACAACAGCCCTCGTGACCCTCCACAGACTCCACACTTTTCTATATTCCAGATTTGATTAATGAGTTGATTTGGAAAACGTGTCACCGGTAATCAATAGACCCTGCTCTAGTGATCTGTTACTTATTGCTAATGGTGTAAGATGGATGCGCTGGCTATATCAGTGTCCTCAGGCCACAGACCATAACGTCAACACCTCACCATAGTTTAGCCTCAACACATTAATGAAAAACTGAAGTCGTACAATTCAGAGCCGACCAGTTCAAACTTAATAGTGCAGCTCCACAAACATCCCCTGCATCAAGTGTGGAGGAGCAGCTAGCAACAAGCAGCTCAGAGAGAAGCTCAGCGGCGTTATACGTAGCCTAGCACATGATGCTTTTATTACCATTTATTACTGATATTTGCAAATAAGATGTTCAAGAAATGTCATTTCATTTTAGTCCATAGACTTCTCTAGCAAAGAATGTGGTGCAATACCTTCACTCCCTTTACCAACATGGAGCTATTTCATATTTCAGCTTCTCCAGCACTGCCTGCGTCAAGATTTAGCACAATACCATCAATCGATTTAAATAAAGAATGAAGTGTGGTGTGATGTGGTgacgcagtaggtggtgctgtcacctcacagcaagaagattgcaggttcgagcctcggctgggtcagtgtgtgtttctgtgtggagtttgcatgttctccccgtgttggcgtgggtttcctccaggtgctccggtttcccccacagcctaaacacatgcagtacaggtgaatttagTAAGCTAAGagattgtcagtagtgtatatgtgtgaatgagtgtgtatgtgtgttttccagtgatgggttgcagctggaagggcatctgctgcgtaaaacatatgctggatgagttggcggttcattctgctgtggcgacacaagattaataaagggactaagccgaaaagtgaataaatgaatgtgatGTGATGGTAAAAATGGTCATCATGCATAAATGCACATGGAGGATTATTAGGAGATGCATCTTCAGGTCTGTCAGGGCCTTAAGGCTGGGATGCGAGTGCACATGGAGAGCTTTTGAGCCTCTGAGAAGGGGAAAGGTCACAGCGGTGACCCCTCAGCATCAGGACAATGGTGCTGAAAGTCCAGTCTTCTGCTGGAGCTGAAACACCGAGGCATCGATCAGCCGGAGGATTCTCCTGTCCACAGCCGGATGATGTATCTGTAATTACAGAGTTCGTCTGAGGCATCGTGGGTCATGGTTTGTGAAGGAGTGATATGGATGAGGTGCTGAAATACTGCATATTAGAGCTCTCAGATAGGATATAAAGGCAGGATGGAGCCACTGAGGACTGTGAACGGACACACTCAGACCTGAAGTGTGCACCACTGCGCGCTGGACCAGAGGGCATGATGAATGGTAATGTAGTCCTTTCGTATTTTGATTGTACTTTTGGAGACTTGTGATTAGTGTTTTTGTCTTGGTTTAAGGTAAATATGATGTTGGAACTTGCTGTGAAGTGATTTCAGAGAAGGTGTCTTTTTCCTGTGATTTTAAAGCTGAAGGTGTAAAATGTCACAAGTGTCACTGTCTGCAATCTCTGCATTCACTCCTAATCAAACGGTTGGAAGATTTGTGTTACGTTAATTATGAAGAGAGACTCATCTGCTCAACCAAGATATgtactattttttaataaaaataaatgaaaaatggtAATATTGAAAAGAACAGGTCAACATTTGAAGCACTTTCATTCTGACTCTAAACATTGAAGCTATTGAACATTTGACCAAAACGTTTTCAAAACTGTCCAAGAAATGGTTTTTGAATAGTTTTAGGCCAACTTTAATGAAATGCTTTGATCCACTTCTAATGTTGACCActatattttgataaataataataataaaataataaaataacgtgtaaatacataaaataaaaaaaaaaacactgaaacagcccagagtcctgatctaaacctgaCAGTTCTGAGAGAGAAACTAGCAGTTTGCTCTGGGAGACTAGTCATATCCACTGTGTGTCTGAcctgtgtgtgtagtgtgtgatCTGTGTGtatcatctgtgtttgtgtgtttgtgtgtgatctGTGTGTctgatctctgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtttgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtagtgtgtggtCTGACTCAGGCATGTCCTCCTGAAGAGGGTCGCTCCTGCAGTAAAGCTCCAGAAGTGTCCAGCGTCCGGGTTCAGCTGGAGATGCAGAGTCTGTGGAGGCAGTTTGACCAGCTCGGCACAGAGATGATCGTGACCAAAGCTGGAAGGTTTTCTTACACTTTTACTTGTGTGTCATTCCATCTTTACAGAGTCTGATAAGATGACCCGAATCTTTGATGATGGCTCAGGGTTAGAGAACTGAACTCTGTCAGTGCTGTACTCTCCTGTGTATCAGTCAGTGGTCAGCAGCTGTAGTCTGATGTTGGTTGTCTTCATACAGAAGGATGTTTCCCACGTTTCAAGTGCACATATCAGGCATGGATCCTGCAGCAGAGTATGTGCTCCTGATGGACTTTATTCCTGTTGATGACAAACGATACAGGTACTACAAACTAATCCAAATGAATGTATCTCTGTTTAGCCTGTAATTGATGTCTAACAATAACCGCAGTATAAACACAATCAAGAGGTTCAGCAGAAATACAATGCAAACATCATCAAATCTCACGATGCATTAAAATATGTATATCACTACGTTTTTCACATTGATGAGCCATAACATCATGACCACCTCCAGTCTAGAGGACTGAGCCTGTTCCTTATCTCTGCTAATGTCTTCACCTCCCAATATGGCTGAGATGAACACATGGAAAAGC
>TCONS_00017528
GCTGAAGCCCTTCATGGACGACTACCTGGTCAAGCAGCGTCAGCACATGGAGGAGGTCAGGGCCAAGCTGGAGCCTGTGGTCCTCAGCCTGAAGGAGAAGATCCCACCCAACTGGGAGGAGACCAAGTCCAAGCTGATGCCCATCCTGGAGGCCATCCGAGGCAAGGTGGCGGAGAACGTGCAGGAGCTGAGGACCATGCTGGAGCCCTACGTCCAGGAGTACAAGGACCAGATGGAGAAGGGAGCCTTGGAGTTCAGAGAGAAGGTGAAGTCTGGAGAACTGAGGAAAGAGCTGACCGAGCTGGGAGAGCAGGTGAAGCCACACTTCGAGGGCATCTTCAAGGCCCTCCAGAAGTTCGCCAGCAAGGAGTAAAGCGACCGTTTTGTACACCATCCCATCCTCCCTTATCCACGGCTTCTCTCAGAGCATAGCTgatcttttctctctctctctctctctctctctctcacacaaacacacacacacacacacacacacacacactgatacaggCCCGTAGTACACTCATATGCACTTTGtacacatgaccacacacacacagacacacacatgcaggacTTGCGTTCTCTCTAATGGGCAAACTCAGCTAAGAACACTGAATCCTGTTCATTCAAAAACGCCTAGCAAAATccctttgttaagctgctttgtgTTAAAAACTGATGTTCAATGTTCAAtccaatgaaataataaaaataacaaactttCATACT
>TCONS_00017529
AGTCTCTTCCCAGACCAGCCACATCCACAGATCCATGATGAGGTTCGTAGCCCTCGCCCTCACCGTATTCCTGGCAGGTTGCCAGGCCCGGTTCCTGCAGGACGAGCCCCCATCGCAGCTGGAGCATGTGAAGTCTGCACTGCAGGTTTATGCAGATCATCTGAAGCAGGCCGCACACAAGTCCCTCACTCACCTCGACGACACCGAGTTCAAAGATTACAAAGTCTTCCTGGGCCAGTCCATCGACAACCTCCATTCCCACTTCCAGAACTTCTTCCAGGTCATCACGCCTCTGGGCTCTCAGGTGATGGATGCCACCAACCCCATCCGCGAGAAGCTGAACAAGGACATGGAGGACCTGCGCAAGGACATCGAGCCCAAGCGCGAGGAGCTCAGAGCCGTGCTGGAGAAACACTTCAATGAGTACAGGGATGAGCTGAAGCCCTTCATGGACGACTACCTGGTCAAGCAGCGTCAGCACATGGAGGAGGTCAGGGCCAAGCTGGAGCCTGTGGTCCTCAGCCTGAAGGAGAAGATCCCACCCAACTGGGAGGAGACCAAGTCCAAGCTGATGCCCATCCTGGAGGCCATCCGAGGCAAGGTGGCGGAGAACGTGCAGGAGCTGAGGACCATGCTGGAGCCCTACGTCCAGGAGTACAAGGACCAGATGGAGAAGGGAGCCTTGGAGTTCAGAGAGAAGGTGAAGTCTGGAGAACTGAGGAAAGAGCTGACCGAGCTGGGAGAGCAGGTGAAGCCACACTTCGAGGGCATCTTCAAGGCCCTCCAGAAGTTCGCCAGCAAGGAGTAAAGCGACCGTTTTGTACACCATCCCATCCTCCCTTATCCACGGCTTCTCTCAGAGCATAGCTgatcttttctctctctctctctctctctctctctcacacaaacacacacacacacacacacacacacacactgatacaggCCCGTAGTACACTCATATGCACTTTGtacacatgaccacacacacacagacacacacatgcaggacTTGCGTTCTCTCTAATGGGCAAACTCAGCTAAGAACACTGAATCCTGTTCATTCAAAAACGCCTAGCAAAATccctttgttaagctgctttgtgTTAAAAACTGATGTTCAATGTTCAAtccaatgaaataataaaaataacaaactttCATACT

Function

symbol description
apoa1b Predicted to enable cholesterol binding activity; phosphatidylcholine-sterol O-acyltransferase activator activity; and phospholipid binding activity. Predicted to be involved in several processes, including lipid homeostasis; lipid transport; and plasma lipoprotein particle organization. Predicted to act upstream of or within lipid transport. Predicted to be located in extracellular region. Predicted to be part of chylomicron and high-density lipoprotein particle. Is expressed in blood; liver; otolith; and yolk syncytial layer. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); familial visceral amyloidosis; hypolipoproteinemia (multiple); non-alcoholic steatohepatitis; and systemic lupus erythematosus. Orthologous to human APOA1 (apolipoprotein A1).

GO:

id name namespace
GO:0010873 positive regulation of cholesterol esterification biological_process
GO:0033700 phospholipid efflux biological_process
GO:0042157 lipoprotein metabolic process biological_process
GO:0046889 positive regulation of lipid biosynthetic process biological_process
GO:0006695 cholesterol biosynthetic process biological_process
GO:0070328 triglyceride homeostasis biological_process
GO:0043691 reverse cholesterol transport biological_process
GO:0042632 cholesterol homeostasis biological_process
GO:0034372 very-low-density lipoprotein particle remodeling biological_process
GO:0034380 high-density lipoprotein particle assembly biological_process
GO:0033344 cholesterol efflux biological_process
GO:0006869 lipid transport biological_process
GO:0005576 extracellular region cellular_component
GO:0042627 chylomicron cellular_component
GO:0034364 high-density lipoprotein particle cellular_component
GO:0015485 cholesterol binding molecular_function
GO:0005543 phospholipid binding molecular_function
GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity molecular_function
GO:0008289 lipid binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-050302-172 Predicted to enable cholesterol binding activity; phosphatidylcholine-sterol O-acyltransferase activator activity; and phospholipid binding activity. Predicted to be involved in several processes, including lipid homeostasis; lipid transport; and plasma lipoprotein particle organization. Predicted to act upstream of or within lipid transport. Predicted to be located in extracellular region. Predicted to be part of chylomicron and high-density lipoprotein particle. Is expressed in blood; liver; otolith; and yolk syncytial layer. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); familial visceral amyloidosis; hypolipoproteinemia (multiple); non-alcoholic steatohepatitis; and systemic lupus erythematosus. Orthologous to human APOA1 (apolipoprotein A1).

Ensembl:

ensembl_id ENSDARG00000101324

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00017527 False 4170 mRNA 0.45 3 102925 107900
TCONS_00017528 False 735 mRNA 0.50 1 105955 106689
TCONS_00017529 True 1170 mRNA 0.53 4 105955 108414

Neighbor

gene id symbol gene type direction distance location
XLOC_008864 bace1 coding downstream 5720 93131 ~ 97205 (-)
XLOC_008863 NA coding downstream 13686 84837 ~ 89239 (-)
XLOC_008862 NA coding downstream 18710 81571 ~ 84215 (-)
XLOC_008860 cyp2y3 coding downstream 70774 16175 ~ 32151 (-)
XLOC_008866 BX640522.1 coding upstream 10643 119057 ~ 163586 (-)
XLOC_008867 limk1a coding upstream 59588 168002 ~ 252813 (-)
XLOC_008868 NA coding upstream 146871 255285 ~ 260813 (-)
XLOC_008869 BX640522.2 coding upstream 174317 282731 ~ 290507 (-)
XLOC_008870 FP102887.1 coding upstream 241037 349451 ~ 349567 (-)
XLOC_008871 NA non-coding upstream 265966 374380 ~ 378187 (-)
XLOC_008873 CABZ01056628.1 non-coding upstream 317281 425695 ~ 425756 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000092_03860647_03862519 NA coding CI01000092 null 3860432 ~ 3863147 (-)