CI01000033_00425156_00470606 (DNM2A, DNM2)


Basic Information

Item Value
gene id CI01000033_00425156_00470606
gene name DNM2A, DNM2
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000033
NCBI id null
chromosome length 1934898
location 425156 ~ 470676 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000033_00425156_00470606.mRNA
ATGGGCAACCGGGGGATGGAGGATTTGATCCCCCTGATCAATAAACTCCAAGATGCTTTCAGTTCCATTGGCCAAAGTTGTAACTTGGATCTGCCGCAGATAGCCGTGGTCGGAGGACAGAGCGCCGGAAAAAGCTCCGTGCTGGAAAATTTCGTCGGCAGGGATTTCCTTCCGCGAGGCTCAGGCATCGTCACCCGCAGGCCTCTTATTCTGCAGCTAGTTAACAACAAAGCTGAATATGCTGAGTTCTTGCACTGCAAAGGGAGGAAGTTTGTGGACTTTGATGAAGTCCGGCAGGAAATTGAAGCAGAAACCGACAGGATTACAGGGTCCAACAAGGGCATCTCTCCTATTCCCATCAACCTCAGGGTGTACTCTCCACACGTATTGAATCTGACTCTCATTGATTTGCCCGGAATGACCAAGGTTGCGGTGGGCGACCAGCCGGTAGACATCGAGCACCAGATTCGAGACATGATTATGCAGTTCATCACTAGGGAGAGCTGCCTGATCCTCGCCGTCACCCCGGCCAACACTGACTTGGCCAACTCTGATGCCCTCAAGGTGGCTAAGGAGGTGGACCCTCAAGGACTGCGTACCATTGGTGTGATTACTAAACTGGATCTAATGGATGAGGGTACAGATGCCCGGGATATCCTGGAAAATAAACTCTTACCACTCCGTAGAGGTTATATTGGTGTAGTGAACCGAAGTCAGAAAGACATAGATGGCAAAAAGGATATTCGTGCTGCACTTGCGGCAGAAAGGAAATTCTTCCTATCCCATCCCAGCTACAGACACATGGCTGAAAGAATGGGAACACCACACCTGCAGAAGACCCTCAACCAGCAATTGACCAACCACATCCGGGACACGCTACCCGGCTTGCGCAGCAAACTCCAGTCTCAGCTTCTCTCACTGGAAAAGGAGGTAGAAGAGTATAAAAATTTCCGCCCGGATGACCCTACGCGAAAGACCAAGGCTCTGCTGCAGATGGTCCAGCAGTTTGGAGTGGACTTTGAGAAATGCATCGAAGGGTCCGGAGACCAGGTGGACACAGCAGAGTTGTCTGGAGGTGCCCGGATTAACCGAATTTTCCATGAGCGCTTCCCCTTTGAGCTGGTCAAGATTGTGTTTGATGAGAAGGAGCTCCGGCGAGAAATCAGTCACGCCATTAAGAACGTCCATGATCTGGCGTTTGAAGCCATCGTGAAAAAGCAGATCATTAAGCTGAAAGAGCCCTGTCTGAAATGTATCGATCTGGTTATTCAAGAGCTCATCAACACATTCAGGCAGTGCACCAACAAGGTACTGCAGTACCCCAGCCTGGCCACAGGGGGGCTTCCAGTGAGGGGAACGGGGTTGTTCACCCCTGACTTGGCTTTTGAGACTATAGTGAAAAAGCAGATCCGCAAACTGAAAGAGCCCAGCCTGAAATGTGTGGACCTGGTGGTGTCTGAACTCACCACCCTCGTCAGGAAGAGTGCTAACAAGCTAAGCTCTTACCCCAGACTGCGAGAAGAGACAGAGAGGATCGTCACTACTTACGTCAGAGAAAGAGAAGGAAAGACCAAGGACCAGGTCCTTCTGCTGATTGATATCGAGCTGTCATACATCAACACCAACCATGAGGACTTCATTGGATTTGCAAATCTTGACTTCAGACGGATGGATGACGGTACCATACCAGGGTACGGCAACAACAGTGGCAGGATCGCTTACACCCAGAGCACCAAGGAGGTTTACACAGACATCATTTTACTGTTGTGGTATTCTAACAATACAGACAGCAGCATGCAGTCAGTGTCTAATCGTTGTTTTCTGTATGTTTCCACCACCTACAGCGCCCAGCAAAGAAATATTGTCAATAAGAAGAGGGCCATTCCCAATCAGCTATGTGGCCTGAGAGAAGGCGAAGTCGAGAAGTTTCACTCCGACTTTACGGAGAACAAAGCAAATGGAAAGGGGGAAAAGGGACGTATCTTAGAAAAGCTTGTGGTGATCCGTAAAGGCTGGCTAACTCTCAACATCAGCATCATGAAAGGCGGCTCAAAGGAGTACTGGTTCGTCCTCACAGCCGAATCGCTGTCCTGGTACAAGGACGAGGAGGAAAAAGAGAAGAAATACATGCTTCCCCTGGACAACCTGAAGCTCAGAGACGTGGAGAAAGGCTTCATGTCCAATAAGCACATTTTTGGTATCTTCAACACTGAGCAAAGGAACGTGTATAAGGACTTGCGTCAGATCGAGCTGGCCTGTGACTCGCAGGAGGACATGGATAGCTGGAAAGCCTCTTTTCTCAGAGCAGGCGTTTATCCTGAGAAAGATCAGCTAGAGAGGCAGGTGGAGACCATCCGTAACCTGGTGGACTCCTACATTGGTATCGTCAACAAAACCATCAGAGACCTCATGCCCAAGACTATCATGCATCTCATGATCAACAGCGCTAAAGACTTCATCCATTCAGAGCTGCTGGCATACCTGTACTCCTCAGGAGATCAGAACAGTCTGATGGAGGAGTCTGCTGACCAGGCCCAGCGCAGAGACGAGATGCTGCGTATGTACCATGCCATCAAAGAGGCTCTCAACATCATCGGAGACATTAGCACCAGCACCATATCCACTCCCGTACCTCCGCCCGTGAACGACAGCTGGATGCCGGAGACGAGTGTAGTGTGTTCATATACTTTTAATTCTATATTTCTTCTTTTCCTGTCCTGTGTAGCCCCACCCCCCAGCGCAGACCGCCTTCATCGGCCCCACCCCCCAGCAGACCTCCAGCACCCCGCCCATTCCCTCTCGGCCAGGCCTGTCCATGAATGCCTTCGGCAACAGCAGCCAGGATCCTTTCAGTGCCCCTCCTCAGATCCCATCCCGTCCCGCCCGTGTCCCTCCGGGTATCCCCAGCTCTCATTCTTCTCTCACTAGCAGTTGCATTCAGATATTCTCTCCTGTCACATAACAATTTTTTCCTAATTTTTTTCTCAGCATATTCTTA

Function

symbol description
dnm2a Predicted to enable GTPase activity and microtubule binding activity. Acts upstream of or within several processes, including chordate embryonic development; convergent extension; and somite development. Predicted to be located in cytoskeleton. Predicted to be active in several cellular components, including microtubule; plasma membrane; and synapse. Is expressed in several structures, including central nervous system; liver; otic vesicle; paraxial mesoderm; and pericardial region. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease dominant intermediate B; centronuclear myopathy 1; and lethal congenital contracture syndrome. Orthologous to human DNM2 (dynamin 2).
dnm2 Enables SH3 domain binding activity. Involved in negative regulation of membrane tubulation; receptor internalization; and transferrin transport. Located in several cellular components, including Golgi apparatus; microtubule; and postsynaptic membrane. Implicated in Charcot-Marie-Tooth disease dominant intermediate B; centronuclear myopathy 1; and lethal congenital contracture syndrome.

GO:

id name namespace
GO:0006897 endocytosis biological_process

KEGG:

id description
K01528 DNM1_3; dynamin 1/3

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000033_00425156_00470606.mRNA True 2998 mRNA 0.50 25 425156 470676

Neighbor

gene id symbol gene type direction distance location
CI01000033_00263817_00267075 PMP22A coding upstream 157728 263766 ~ 267428 (+)
CI01000033_00227674_00228681 CDC42EP4A coding upstream 195806 227674 ~ 229350 (+)
CI01000033_00131331_00201065 SDK2, SDK2B coding upstream 223837 131331 ~ 201319 (+)
CI01000033_00039492_00046280 NA coding upstream 378250 39160 ~ 46906 (+)
CI01000033_00000373_00008090 NA coding upstream 416993 373 ~ 8163 (+)
CI01000033_00497624_00498442 NA coding downstream 26948 497624 ~ 498479 (+)
CI01000033_00523275_00559791 PPAP2D coding downstream 52599 523275 ~ 559791 (+)
CI01000033_00702445_00711580 NA coding downstream 231587 702263 ~ 711893 (+)
CI01000033_00715688_00732487 NA coding downstream 244420 715096 ~ 732713 (+)
CI01000033_00745197_00770385 NA coding downstream 274453 745129 ~ 770734 (+)
G167851 NA non-coding upstream 66997 357765 ~ 358159 (+)
G167837 NA non-coding upstream 104641 320132 ~ 320515 (+)
G167749 NA non-coding upstream 126045 298497 ~ 299111 (+)
G167741 NA non-coding upstream 126765 243303 ~ 298391 (+)
G167766 NA non-coding upstream 146833 217197 ~ 278323 (+)
G167744 NA non-coding downstream 28310 498986 ~ 500752 (+)
G167883 NA non-coding downstream 47644 518320 ~ 518521 (+)
G167885 NA non-coding downstream 48668 519344 ~ 519553 (+)
G167899 NA non-coding downstream 121967 592643 ~ 593041 (+)
G167905 NA non-coding downstream 129041 599717 ~ 599952 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
bowfin (Amia calva) AMCG00020008 dnm1a,dnm1,LOC108423695 coding CM030127.1 CM030127.1 6224949 ~ 6267200 (+)