XLOC_009169 (dlc)


Basic Information

Item Value
gene id XLOC_009169
gene name dlc
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007126.7
NCBI id CM002899.2
chromosome length 48040578
location 20463448 ~ 20468302 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00018037
AAGAAACGTAACTGAAGGGTCCAAAGTCCCCTGGAGCTagaaatctgtttttatttgctttgtagGCTCCAAACACATGCGACATTGAGATACTTTTTTATAAGAAATGTTCATTCGTTTAACTTTTTAACTTTACGCATTTTTACAACTACTTTTCCCCTTTAAATCGTGGATAATACTACAAACATTCATATCGGACTACTCTCACAGTCTGCTATCGTTCAGTAGCAGACAAGAAGGCAAAGATGGCTCGTGTTTTATTAAcgtgcttttttattttgatatcatCGCATTTGGGGAAATCATCCGGTGTGTTTGAGTTGAAAGTTCTGTCTTTCACAAGCACGAGCAGTGTGTGTAAAGGGTCCAGCGACTGCCAGATCTTTTTCCGTGTTTGCCTGAAGCACTCGCAAGCACTCATATTACCTGAGCCGCCGTGCACCTACGGCACCGGAATGTCAGAAATACTGAGCGCGGACTCCATCTCCAGCAGTGCGTATATAAGCGTGCCTTTTAATTTCAAGTGGCCGGGAATCGTCTCTTTGATAATCGAAACCTGGAACGCAGAAACCTCTGACCAGTCAACAGaGAATAACAACAACATGATAAGCCGTTTGGCCACCAAAAGAAGACTCGCTATCGGTGAGGACTGGTCTCAGGACGTGCATCTCGGTGAGCAAAGCCAACTGCGCTTTTCTTATCGTGTCGTGTGCGATGAATTCTACCACGGCGAGGAATGCTCGGATTTCTGCCGCCCACGGAATGATACCTTCGGCCACTTCAACTGTGACGCCGCTGGCAACAGAATTTGCCTTCCTGGATGGAAAGGCGATTATTGCACCGAACCCATCTGCTTGTCTGGCTGTAGTGAGGAGAACGGTTATTGTGAGGCCCCCGGTGAGTGCAAGTGCCGGATTGGATGGGAAGGCCCCCTCTGTGATGAGTGCACGCGGCACCCGGGGTGCTTGCATGGCACCTGCAACCAGCCTTTTCAGTGCACTTGCAAAGAAGGTTGGGGCGGTCTATTTTGCAATGAGGATCTGAACTTTTGCACTAATCACAAGCCCTGTAGAAATGACGCCACGTGTACCAACACCGGCCAGGGCAGCTACACCTGCATTTGCAAGCCTGGCTTCAGTGGCAAAAACTGTGAGATCGAAACCAATGAGTGTGACAGCAACCCCTGCAAGAATGGAGGCAGTTGCAATGACCAGGAGAATGATTACACTTGTACATGCCCGCAAGGCTTCTATGGCAAGAACTGCGAGGTCAGCGCCATGACCTGTGCCGATGGACCCTGCTTCAATGGTGGAACCTGCATGGAGAAGGGATCCGGTAGCTATTCCTGCCGCTGCCCTCCTGGATACATGGGCTCCAACTGTGAGAAGAAAATCGACCGGTGCAGCAGTGACCCCTGTGCTAACGgtggcCAGTGTCTCGATTTGGGCAACAAAGCGACGTGCCGTTGCCGGCCCGGGTTCACAGGCTCACGTTGTGAAACAAACATTGACGACTGCTCAAGCAACCCCTGTCAAAATGCAGGCACCTGCGTGGATGGTATCAACGGGTACACCTGCACATGCACGCTTGGTTTCTCAGGCAAGGACTGTAGGGTTCGCTCTGACGCCTGCAGTTTCATGCCCTGCCAGAACGGAGGAACCTGCTACACTCACTTCTCTGGGCCTGTCTGCCAGTGCCCGGCAGGCTTCATGGGCACACAGTGCGAGTACAAACAGAAGCCCACGCCTGTGAACAGCCCTGCTCTTCCAGCAGCCTTAATAGTCTCATTTACTCTAGGCCTCATTACTCTAACCTTAGTGATCTGTGCTGCCATTGTGGTCCTGCGACAGATGCGTCAGAACCACAAAGCCAGCTCAACCACAGTTCGAAACAACCTGGATTCTGTCAATAATCGCATTTCTTTGAGCCCAACCTCCACTTTAGGTAGAGAGAAGGAGGCCTTCCTTATTCCTGGTGGCCCATTTAAGGTGTCCAATAAAGATATGGCGCTCAGATCCACCTCTGTAGACACACATTCCAGTGACAAATCAAACTATAAGCAGAAGATGGTGGACTACAATCTGAGCATTGATGAAAAGCACACAAACAACAAACTAGAGAAAAACTCTGAATCAACATTGCTGGTTCCACCTTTAAACTATCCAAAAGAGGGAGTGTATCATCCTGTGTACATCATTCCCGAACACATAGAACAACGTGTGTTTGCTACTGAGGTATAGCAGAATTCTTCAATCTGGAGCACCTCAAACACCAGTGGGCCTGACCACAAAAATGTTTACAGTCTCTAAGGACAAAAGGAAGACGTGAAGAGAGTATATATCACatgcattatattatttatttattcatgctgctCACTAAATGGACTACTTCTTGATATGGATAATGAATTTGTGAAGACAAGCAAGAGACTTGAAGACCCGTGGAACAACTTGCATTATTTGCACTATTTCCTTTCCCTTTTTTAATGACCCAAacagaatttttatatatttgtcatCATATTTAAATTGTACATAGACACAAGAACTCTCTGGAAGAGCTGAAGAATCAAGGATTTGATAATCACAGAAGCCTTGAAAAGGAAGAAAATAGGCATCCTGAAGTTCATCTAACTCTCTGAATCACATGGAGCCCAAACAATCAGCCTTATGGGTGGAGGAGGTGCAACTGAAGGATCTGGAACTGTGACTGTGGAgtatttgccttttatttttattttttcgataTGGTTCGAAATGCTATTTATAAATGGAACTGTGATGAGAAGCAATCAAACTGAACAAAACAAGTTGTTCTGGCTGTGAACAATGTGAACAACTGTCTTGGAAATGTACAGTTTTATGCGGCAGTGATTTTACTTAGTGCCTACAATGGATCTGACTAtcagtgacattttctcaaaCCAAACCCAATCTCAATTAAGTGCCTCATTCTTTAATGTGCTACAGCTCAGTTACAAAGGTACTCCTTAGAAACACTGAAAAGAgcctttttttaaacactatagGAGTATGCTTTTCGACAGTAGATGTTTGGGTTGATTTGAGTACAGTTGTTTAAACAGCGATGGATGATGGATGCTGTTGTGTACAGCGGCCATCCTGTCAACATTCACTGCTGGTAATCTATTTCCGACATTCCCAAGGCTTGAAAGGACCCTTGGTCCAAACTGATAGCCTCAACATTGTCAAGATTTCCTGGTTTTGTAATCCTCTGCAATCAGAGTGTTTTTCAAAATTCGCAACAACATAGATTGTTCTATGTCTTTTCctttcctattttattttttattttttagtatgtGGCATTTGTTCCGTcatcttcattttttaaaaccatttaaaccaaaatagatgatacttttatattttataccgTCTTCCTTAATTTAACAATGCAATAATGTACAAAATCTTGAGATAATCCACTATTTAATTGGActgtaaatattttgtatttatgagAGATGaatgtatatatgtttatgtattttgcaaatatatatatatattttttcatataaataAACCCCCGAATAATTTA
>TCONS_00018038
AACAACCTGGATTCTGTCAATAATCGCATTTCTTTGAGCCCAACCTCCACTTTAGGTAGAGAGAAGGAGGCCTTCCTTATTCCTGGTGGCCCATTTAAGGTGTCCAATAAAGATATGGCGCTCAGATCCACCTCTGTAGACACACATTCCAGTGACAAATCAAACTATAAGCAGAAGATGGTGGACTACAATCTGAGCATTGATGAAAAGCACACAAACAACAAACTAGAGTAAGTTCATGTTCAAGTAATCCTCAGTTTCTGttcacaatttctgtttcattttaTATGCATAACGTGGATGTGTTTCCGTAATTTCAGGAAAAACTCTGAATCAACATTGCTGGTTCCACCTTTAAACTATCCAAAAGAGGGAGTGTATCATCCTGTGTACATCATTCCCGAACACATAGAACAACGTGTGTTTGCTACTGAGGTATAGCAGAATTCTTCAATCTGGAGCACCTCAAACACCAGTGGGCCTGACCACAAAAATGTTTACAGTCTCTAAGGACAAAAGGAAGACGTGAAGAGAGTATATATCACatgcattatattatttatttattcatgctgctCACTAAATGGACTACTTCTTGATATGGATAATGAATTTGTGAAGACAAGCAAGAGACTTGAAGACCCGTGGAACAACTTGCATTATTTGCACTATTTCCTTTCCCTTTTTTAATGACCCAAacagaatttttatatatttgtcatCATATT

Function

symbol description
dlc Enables PDZ domain binding activity and identical protein binding activity. Acts upstream of or within several processes, including blood vessel development; neuron differentiation; and somite development. Located in perinuclear region of cytoplasm and plasma membrane. Is expressed in several structures, including immature eye; integument; mesoderm; nervous system; and trunk. Human ortholog(s) of this gene implicated in dysostosis and spondylocostal dysostosis. Orthologous to human DLL1 (delta like canonical Notch ligand 1) and DLL3 (delta like canonical Notch ligand 3).

GO:

id name namespace
GO:0002244 hematopoietic progenitor cell differentiation biological_process
GO:0045746 negative regulation of Notch signaling pathway biological_process
GO:0007219 Notch signaling pathway biological_process
GO:0001756 somitogenesis biological_process
GO:0001757 somite specification biological_process
GO:0030154 cell differentiation biological_process
GO:0048514 blood vessel morphogenesis biological_process
GO:0007275 multicellular organism development biological_process
GO:0060218 hematopoietic stem cell differentiation biological_process
GO:0035907 dorsal aorta development biological_process
GO:0048666 neuron development biological_process
GO:0061056 sclerotome development biological_process
GO:0007154 cell communication biological_process
GO:0060842 arterial endothelial cell differentiation biological_process
GO:0021514 ventral spinal cord interneuron differentiation biological_process
GO:0048471 perinuclear region of cytoplasm cellular_component
GO:0005886 plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005112 Notch binding molecular_function
GO:0005509 calcium ion binding molecular_function
GO:0030165 PDZ domain binding molecular_function
GO:0042802 identical protein binding molecular_function

KEGG:

id description
ko04131 Membrane trafficking

ZFIN:

id description
ZDB-GENE-000125-4 Enables PDZ domain binding activity and identical protein binding activity. Acts upstream of or within several processes, including blood vessel development; neuron differentiation; and somite development. Located in perinuclear region of cytoplasm and plasma membrane. Is expressed in several structures, including immature eye; integument; mesoderm; nervous system; and trunk. Human ortholog(s) of this gene implicated in dysostosis and spondylocostal dysostosis. Orthologous to human DLL1 (delta like canonical Notch ligand 1) and DLL3 (delta like canonical Notch ligand 3).

Ensembl:

ensembl_id ENSDARG00000002336

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00018037 False 3567 mRNA 0.44 9 20463448 20468302
TCONS_00018038 True 728 lncRNA 0.38 2 20464488 20465319

Neighbor

gene id symbol gene type direction distance location
XLOC_009168 chp2 coding downstream 51162 20406143 ~ 20412286 (-)
XLOC_009167 rnaset2l coding downstream 63010 20395309 ~ 20400438 (-)
XLOC_009165 CR626887.3 coding downstream 82349 20340022 ~ 20381099 (-)
XLOC_009166 CR626887.2 coding downstream 117716 20344912 ~ 20345732 (-)
XLOC_009164 NA coding downstream 181655 20253743 ~ 20281793 (-)
XLOC_009170 timm50 coding upstream 7392 20475694 ~ 20528494 (-)
XLOC_009171 tpst1 coding upstream 184384 20652686 ~ 20781116 (-)
XLOC_009172 CR848784.4 coding upstream 329826 20798128 ~ 20799830 (-)
XLOC_009173 CR848784.5 coding upstream 341407 20809709 ~ 20811411 (-)
XLOC_009174 CR848784.2 coding upstream 360119 20828421 ~ 20830125 (-)
XLOC_009163 AL928724.1 non-coding downstream 223850 20238428 ~ 20239598 (-)
XLOC_009158 CR848757.1 non-coding downstream 530600 19929495 ~ 19932848 (-)
XLOC_009157 NA non-coding downstream 669837 19784491 ~ 19793611 (-)
XLOC_009178 BX548078.1 non-coding upstream 491767 20960069 ~ 20978248 (-)
XLOC_009180 CR626907.2 non-coding upstream 611524 21079826 ~ 21109608 (-)

Expression


Co-expression Network