XLOC_009170 (timm50)


Basic Information

Item Value
gene id XLOC_009170
gene name timm50
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007126.7
NCBI id CM002899.2
chromosome length 48040578
location 20475694 ~ 20528494 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00018039
GCGCTCCGGGTACGAACTGCATCATATTCAAGATGTCGGCGGTGTCTGTGTATCCCATGTGTGTCCGGGCGAGCCGGGGCCTGCTCAGACTGAGGCAGGGGGCCCGCTGCTCCACGGCCCCTCCGCTGCTGGATGTCGTCCGGCCTTTATCCGCTGACACGTCCAGTAGCAGCGCAACAGGGGGACTGGCACAGGCGATACTGCAGGAAAGGCTtcagcagcagcagaagagccAGGAACAGCCTCCTCCAGAGGGTGAAGACTCTGGCCACAAGCAAGATGAGCAGGGCGAGGACAAGAAACAGAAAGAGAACACTGCATACGCCAAGAAGATGGTCCTTCGGTTAGCAGGAATTATGGGACTTGGAGGCACAGTTGGCATTGTATATATATTTGGCAGCAATTCTGTGGATGAACAAGGAAATAAGattCCAGATGAGTTTGATAATGATGTTCCTGTCATCCAGCAGCTTAGAAGAACCTTTAAATATTTCAAAGATTACAGACAGatGATCATCGAGCCCACAAGCCCAAAGCTTCTTCCAGACCCTCTACGAGAGCCTTATTACCAGCCTCCATATACTCTGGTGCTGGAGCTCACAGATGTCCTTCTCCATCCAGAGTGGTCGTTGGCCACAGGTTGGCGTTTTAAGAAGAGGCCTGGCATCGACTACTTGTTTCAGCAATTGGCGCCACTTTATGAGATAGTCATCTTCACATCAGAGACAGGCATGACAGCATACCCCTTGATCGACAGCATAGACCCTCAAGGATTCGTGATGTACCGACTCTTCAGGGATGCCACACGTTACATGGAAGGCCACCATGTTAAGGACGTGTCTTGTTTGAACAGAGACACCTCTAAAGTCATCGTGGTGGACTGTAAGCGGGAGGCTTTCGGTCTGCAGCCCTTCAACGGTTTGGCGCTGTGCAAGTGGGATGGAAACTCAGAGGATCGCACTCTGTATGACCTGGCTGCTTTCCTTAAAACTATTGCCATCAGCGGGGTGGAGGATGTGCGTTCAGTATTAGAGAACTACGCCCATGAGGAAGACCCTATTGAAGCTTTCAAAAGAAGACAGGCACAGCTTGCACAGGAAGAAGAACAGAGAATTTCAGAAATGGCGCAACAGAAGAAACAGGGCTTTTCATTAGGCACCATTGCAGGTCGTTTCTGGTCCCGAAAGCAGCAGTGAAGACTCGTCCTGCTCGCACCACCCGAAACCACCCCGTCTGGACTGTGAGCAGCCATTAAGATGAGGGTCACAGTCGAACAGGAGGACGGTGTAAGTGGGCACACAATGGCATGTGTGGAGAAACATCCAATCGGGCTATGCTGAACAGGATTTTAGGGGTTGGAAAAGGAGTGACCAACTCTAAAAAGACATTCATTCCTGTGAAAGATGGCACTACCTGGACAGAACATGCACATATGATGCTCTTATGTATGATCTCACTGATTAGAAAGGGTTTTGGGGTGGTTGGACCAGTCTCCACAAGAGTAAAAATCACAAACTGAAGAACCGATCATATGTTCATCACGTTGGTCCCATTTGAAACCCGTAACGGATGCTGTAGGCCTGTAATAGCCTGATATTAGACTTCAATGTTTGACTGGCACATGAAGCAAAACCTCGCATTTATGTTGGTGCTGCCAGTGAGTCTGATAAAGCGAGCTCAATCTGGTGCTGTTTCTCTTCATGTCAGAAATGGACCGTCTTGTCTGAGGATGTGCTTGTGGAATGTTCTTTGTATTGCTTTTGTTGTGAAACACCCAGAATATCTccaataaataaactataacaaA

Function

symbol description
timm50 Predicted to enable protein serine/threonine phosphatase activity and protein tyrosine phosphatase activity. Acts upstream of or within apoptotic process. Predicted to be located in mitochondrial inner membrane. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. Is expressed in several structures, including immature eye; margin; midbrain; pectoral fin musculature; and segmental plate. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 9. Orthologous to human TIMM50 (translocase of inner mitochondrial membrane 50).

GO:

id name namespace
GO:0006915 apoptotic process biological_process
GO:0030150 protein import into mitochondrial matrix biological_process
GO:0007006 mitochondrial membrane organization biological_process
GO:0015031 protein transport biological_process
GO:0005743 mitochondrial inner membrane cellular_component
GO:0005744 TIM23 mitochondrial import inner membrane translocase complex cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005739 mitochondrion cellular_component
GO:0016791 phosphatase activity molecular_function
GO:0004721 phosphoprotein phosphatase activity molecular_function
GO:0004722 protein serine/threonine phosphatase activity molecular_function
GO:0004725 protein tyrosine phosphatase activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-040426-1618 Predicted to enable protein serine/threonine phosphatase activity and protein tyrosine phosphatase activity. Acts upstream of or within apoptotic process. Predicted to be located in mitochondrial inner membrane. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. Is expressed in several structures, including immature eye; margin; midbrain; pectoral fin musculature; and segmental plate. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 9. Orthologous to human TIMM50 (translocase of inner mitochondrial membrane 50).

Ensembl:

ensembl_id ENSDARG00000031098

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00018039 True 1807 mRNA 0.49 11 20475694 20528494

Neighbor

gene id symbol gene type direction distance location
XLOC_009169 dlc coding downstream 7392 20463448 ~ 20468302 (-)
XLOC_009168 chp2 coding downstream 63408 20406143 ~ 20412286 (-)
XLOC_009167 rnaset2l coding downstream 75256 20395309 ~ 20400438 (-)
XLOC_009165 CR626887.3 coding downstream 94595 20340022 ~ 20381099 (-)
XLOC_009166 CR626887.2 coding downstream 129962 20344912 ~ 20345732 (-)
XLOC_009171 tpst1 coding upstream 124192 20652686 ~ 20781116 (-)
XLOC_009172 CR848784.4 coding upstream 269634 20798128 ~ 20799830 (-)
XLOC_009173 CR848784.5 coding upstream 281215 20809709 ~ 20811411 (-)
XLOC_009174 CR848784.2 coding upstream 299927 20828421 ~ 20830125 (-)
XLOC_009175 aldh3a2a coding upstream 301652 20830146 ~ 20839910 (-)
XLOC_009164 NA non-coding downstream 193901 20253743 ~ 20281793 (-)
XLOC_009163 AL928724.1 non-coding downstream 236096 20238428 ~ 20239598 (-)
XLOC_009158 CR848757.1 non-coding downstream 542846 19929495 ~ 19932848 (-)
XLOC_009157 NA non-coding downstream 682083 19784491 ~ 19793611 (-)
XLOC_009178 BX548078.1 non-coding upstream 431575 20960069 ~ 20978248 (-)
XLOC_009180 CR626907.2 non-coding upstream 551332 21079826 ~ 21109608 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000053_00296442_00323444 TIMM50 coding CI01000053 null 296442 ~ 323444 (+)