XLOC_009945 (nsmce2)


Basic Information

Item Value
gene id XLOC_009945
gene name nsmce2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007127.7
NCBI id CM002900.2
chromosome length 55266484
location 25664078 ~ 25672591 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00019813
CTACTTTTGGCGAAGGAAGGTTGTGCAGAGATGTCTCTCAGTTCAGTGAACTCCACCTTGTCCAATCTCAAGTCCTGTCAAGCAGATGTTGGAGATTATATGGATATGGTGTCCGACGTTGGGCTGGGAATAGTCGAAGCACAAGGTATGGAAAACAGCCCATCTCTGAAGAAACTGGGGGAGATGATTATGGAGTGCTCCAGACTAGACAGTGAAATCAACTGTTTAGTGGAGTCCGTTAATGAAATGACTGCTCAGGTCAGACATGCACCTCCAGAGGCCATGGTTAATCTGAGAGGCTCTGTAAAGGACCGCTTCACTGAGCTGATCGCTGGAGTTTCAGATTCAGACCTGCGAAATCACAGCAAGGTGGTTGCTTTCAAAGAGACAGTCAGGAAATATGCCATGCAAGCTCAGAATCCTGCTGAGAATGAAGAGGAAGAGCTGGATGAGGACATTGCTGTAACACAGAGCCAGACGAACTTCATTTGCCCTCTCACGCAGGTTGAGATGGTCAATCCAATGAAAAACAAGAAATGCAATCATTACTATGACCAAGAGGCGGTGCTTGAAATGATTAAGAACAAGCACAAAAATAGGAAGAAATTTCGTTGTCCAAAGGTTGGCTGTGGAAATGCAGATGTACAGGAGTCAGATCTTGAGCTGGACCTGATTATGAAGAGAATGATCCAGAACCAGAAGAGACAGAGCGGAAAAACCTAAAACTATCATGCAGATGTTATGGCTGTTCTCACTGAATTGGGAGCATGGTTTGTTCTAGAAAAATCCCTGAAAGCTAGAACTGAATGCAAATTTGGTTCATGTTattgtttatatacatttaaagtttacatttgtaatacaaATATTATTGCAC
>TCONS_00019814
GTTGTGCAGAGATGTCTCTCAGTTCAGTGAACTCCACCTTGTCCAATCTCAAGTCCTGTCAAGCAGATGTTGGAGATTATATGGATATGGTGTCCGACGTTGGGCTGGGAATAGTCGAAGCACAAGGTATGGAAAACAGCCCATCTCTGAAGAAACTGGGGGAGATGATTATGGAGTGCTCCAGACTAGACAGTGAAATCAACTGTTTAGTGGAGTCCGTTAATGAAATGACTGCTCAGGTCAGACATGCACCTCCAGAGGCCATGGTTAATCTGAGAGGCTCTGTAAAGGACCGCTTCACTGAGCTGATCGCTGGAGTTTCAGATTCAGACCTGCGAAATCACAGCAAGGTGGTTGCTTTCAAAGAGACAGTCAGGAAATATGCCATGCAAGCTCAGAATCCTGCTGAGAATGAAGAGGAAGAGCTGGATGAGGACATTGCTGTAACACAGAGCCAGACGAACTTCATTTGCCCTCTCACGCAGGTTGAGATGGTCAATCCAATGAAAAACAAGAAATGCAATCATTACTATGACCAAGAGGCGGTGCTTGAAATGATTAAGAACAAGCACAAAAATAGGAAGAAATTTCGTTGTCCAAAGGTTGGCTGTGGAAATGCAGATGTACAGGAGTCAGATCTTGAGCTGGACCTGATTATGAAGAGAATGATCCAGAACCAGAAGAGACAGAGCGGAAAAACCTAAAACTATCATGCAGATGTTATGGCTGTTCTCACTGAATTGGGAGCATGG

Function

symbol description
nsmce2 Predicted to enable SUMO ligase activity. Predicted to be involved in double-strand break repair via homologous recombination and protein sumoylation. Predicted to be part of Smc5-Smc6 complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Seckel syndrome 10. Orthologous to human NSMCE2 (NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase).

GO:

id name namespace
GO:0000724 double-strand break repair via homologous recombination biological_process
GO:0016925 protein sumoylation biological_process
GO:0005634 nucleus cellular_component
GO:0030915 Smc5-Smc6 complex cellular_component
GO:0061665 SUMO ligase activity molecular_function
GO:0019789 SUMO transferase activity molecular_function
GO:0046872 metal ion binding molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG:

id description
ko04121 Ubiquitin system
ko03400 DNA repair and recombination proteins

ZFIN:

id description
ZDB-GENE-081022-128 Predicted to enable SUMO ligase activity. Predicted to be involved in double-strand break repair via homologous recombination and protein sumoylation. Predicted to be part of Smc5-Smc6 complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Seckel syndrome 10. Orthologous to human NSMCE2 (NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase).

Ensembl:

ensembl_id ENSDARG00000076379

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00019813 False 877 mRNA 0.43 7 25664078 25672591
TCONS_00019814 True 752 mRNA 0.45 6 25664387 25672485

Neighbor

gene id symbol gene type direction distance location
XLOC_009944 zhx2a coding upstream 20852 25608778 ~ 25643226 (+)
XLOC_009943 NA coding upstream 84251 25552322 ~ 25579827 (+)
XLOC_009942 NA coding upstream 113424 25544426 ~ 25550654 (+)
XLOC_009941 mylipb coding upstream 115340 25535993 ~ 25548738 (+)
XLOC_009940 jarid2a coding upstream 163349 25407021 ~ 25500729 (+)
XLOC_009946 cblc coding downstream 88510 25761101 ~ 25800819 (+)
XLOC_009947 irgq1 coding downstream 133809 25806400 ~ 25828758 (+)
XLOC_009948 NA coding downstream 158113 25830704 ~ 25831076 (+)
XLOC_009949 NA coding downstream 286305 25958896 ~ 25960158 (+)
XLOC_009950 si:ch73-103b2.1 coding downstream 317352 25989943 ~ 25991643 (+)
XLOC_009938 dre-mir-30b non-coding upstream 322267 25341724 ~ 25341811 (+)
XLOC_009937 dre-mir-30d non-coding upstream 322535 25341416 ~ 25341543 (+)
XLOC_009931 NA non-coding upstream 428985 25233953 ~ 25235093 (+)
XLOC_009954 NA non-coding downstream 402120 26074711 ~ 26080716 (+)
XLOC_009956 BX571761.1 non-coding downstream 739055 26411646 ~ 26411778 (+)
XLOC_009959 CR391910.1 non-coding downstream 822165 26494756 ~ 26495893 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000027_05994575_05998236 NSMCE2 coding CI01000027 null 5994575 ~ 5998353 (+)