RNA id: TCONS_00016988


Basic Information

Item Value
RNA id TCONS_00016988
length 4069
RNA type mRNA
GC content 0.51
exon number 16
gene id XLOC_008491
representative True

Chromosome Information

Item Value
chromosome id NC_007126.7
NCBI id CM002899.2
chromosome length 48040578
location 23208042 ~ 23265405 (+)
genome version GRCz11_2017_zebrafish_Genome
species zebrafish
(Danio rerio)

Sequence

CGCACAGATAGAGAAAGAGAGCTGCAGGAAAAGGGAACATCACGCACGGGGTGTCGATGTGAAAGCAGTTGTTCTACCACGTCCAGACACCCATCAAAACTTATTTTTACGCGTTATTTTTAAACGGGTTCCGCCGCCCTCCCCGAGCGTTTTTAAACACAGCGTCAAACGGCGGTTTGCTGCACGGGGGATTTAATGGGAGTCTTGCATCGGTAAAGCGCTTCTCCCCCCCTTGACGGACCCTCGCTCGAACCGAACCGGACTCGGGCGCTGTCCTCACCGGGGGGTATCCGATCCCAGTTATATTTTGACTGCGAAAACAACACTCCGGAGTCCGAATATGGCAGGAAATCTGAAGAAAGGTGGGGGGCTTATTGGCATGATGAAGGACGCTTTTCAGCCTCACCATCACCTCCACCACTCCCATCACCAGCCCGGAGCCGTGGACAAAAAGACGGTGGAGAAATGCTGGAAATTCATGGATAAGGTGGTACGGTTATGCCAGAACCCCAAATTGGCCTTGAAGAACAGTCCTCCGTACATCCTAGACTTGCTGCCAGATACATACCAGCATCTCCGCACTATCCTGTCTCGATATGAAGGCAAGATGGAAACGCTAGGCGACAACGAGTACTTCCGTGTTTTTATGGAGAACTTGACCAAGAAGACCAAACAGACCATAAGCCTGTTCAAAGATGGCAAAGAGCGAATGTTCGAGGAGAACTCTCAGCCCAGACGGAACTTAACAAAGTTGTCGCTGATTTTCAGTCACATGCTCGCTGAGCTCAAAGCCATCTTTCCTAATGGTCTGTTTCAAGGGGACAACTTCAGAATCACCAAAGCGGATGCCGCAGAGTTCTGGAGAAGATCGTTCGGGGACAAGACCATTGTGCCTTGGAAGGTGTTCCGTCAGGCCCTGCATGAGTTTCACCCCATCAGCTCAGGCCTGGAGGCCATGGCACTGAAATCCACCATCGACCTCACATGCAACGACTACATCTCCGTTTTTGAGTTTGACATCTTCACCAGGCTATTCCAGCCATGGTCGTCATTGTTGAGAAACTGGAACAGCCTGGCAGTGACTCATCCCGGGTACATGGCTTTTCTAACCTATGATGAAGTCAAAGCTCGTCTACAAAAATTCATCCACAAGCCTGGCAGCTATATCTTCAGACTGAGCTGTACGAGGCTCGGACAGTGGGCTATCGGTTACGTCACGGCTGATGGAAACATCTTGCAGACCATTCCTCATAACAAACCCCTCTTCCAGGCCCTCATCGATGGCTTTAGAGAAGGATTCTACCTTTTTCCAGATGGACGCACTCAAAACCCAGACCTCACAGGACTGTGTGAACCCTCACCTCAAGACCATATCAAAGTCACACAGGAGCAATATGAGCTGTACTGTGAGATGGGCTCTACCTTCCAGCTGTGTAAGATTTGTGCTGAGAATGACAAGGATGTGAAGATCGAGCCCTGCGGACACCTCATGTGCACTTCCTGTCTTACAGCCTGGCAGGAGTCAGAAGGCCAAGGCTGCCCATTCTGTCGCTGTGAAATTAAGGGTACAGAGCCCATCGTCGTTGACCCCTTTGATCCTAAGGATCCCAACAGCGCTGCCTCCTATGGCTGCAGGGGCATGTTTGGGGCTGAGGGAGCCCCTTCACCCAGctacgacgatgatgatgatgaccgTTTAGAGGAAACTCCTTTCATGATTAGCAAGCTGGTCGGCTCTAAAGTGGAGAGGCCGCCCTCGCCGATGTCAATCTCCCCTCAGCCCGTCGTTCCTCCAGTACCTCCTCGGCTGGATCTGCTTCCTCTCAGGCCCACCAACCCTCCTGGGGCCTCAAGTCCAGGGGCCACATCCAAGGCCCCTTCCCATCACAAAGACAAGCCATTACCGCTGCCGCCGGCTCTAAGGGATCTGCCACCTCCACCTCCCCCAGACCGTCCACACCCAGCTGGAGCAGACAACCGTCTCCCAAGACGTCCTCTCCCCAGTACGCCTGGAGACCCATCTCGTGACAAACTGCCCCCGGCCCCTCCTAACCGCAACATGCCAGACTGGAACTCCCGGCCTGTACCCAAAGCCCCATCACAGCCACCAGCAAGCGGAGACACCCGTGGATCTCGAGAGCTTTCCAACAGGCACTCTCTGCCTCTCCAACTGCCCTCTACTCTCGATTCCAGAACAGAAGCCCCCAGAAACAACGGCCCTCCCAGCCTCGACCACCAGCTGAGTTTTGGATCATCGAATCCTGCATCGGATTATGACAGTCCAAAAGTAAAGCCGTCTGCCTCGGCTAATGCCATCTATTCCTTGGCAATACGGCCTGTTGCAGCAGCAAGAACACAGACAGGGGAGGAAACCAATGAGAATGACGAGGAGTCCGAGTACATGACTCCATCTTCTCGACCAGTGCTGCCCTCTGCTGCAGGGGAGGCTGTGCCCAGACCACCTCCACCACTCTCACTCAGTCCCAGAAGTATGCTCAATGAATTAGAGTCAGAAAGTCCACAGATGTATGAAGCCATGTACAACATCCAAGCACAGGCCCTCACAGCTTCTGCACCACAGGCCAGAGACTCGGATTACTCCGAATTGCCTCCTTTGACCTGCTCTAATGGCCCGCGGGATCCTGTCGGTGCATAtgctgaggaggaggaggaggaggagaacagCTATGACTATCCCAAACCTCATCTATCTGCAGCTCTAGCCCGACGCACGCTTTCAGATGCTAACTCACCATCCTCCTCAGCCTTCAGCCGCCTCTCCTTTGACAGTGACCTTGGAGCAGCTGCAACTGTCCTGGACCCCTCTGAAGCCCCCGAGCGGCCTCCTAAGCCATTGCCCCGTCGCATCAACTCGGATCGCAGACCCAGTCCAGTTCCCCCCGGGGCGAGTCCAGGCCCCAGCCAGCAGATCAGCAGTGAGATCGAGCACCTCTTGAGCCAGGGATACTCCCATCAGGACATCCAAAAAGCCCTAATGATTGCACAGAACAATATTGAAATGGCCAAGAACATCCTGAGGGAGTTTGTGTCCATCCCTTCTACTGCACATATCTTAACATAACGAAACTTCTCAGTGCACCCAGTCGCAGCCCGGCCACGCTCGCCTCGTATTCGTCTTGGACTTCAGAAGTCAGTGGCGTGACCCTGCATTCTTGCTCTAGCGATGGCAAGAGCCTGTTTCTCCGTAACGCTTCTTGGATTCTCTGTCCTCCTTCGTGCGCAAGGAACAGCAAGGGTTTTTTTGCGGCCGCTTCTTCAGCCTGAAGCCAACGCATGTCCCTTGAGgctaaacaaagacaaaaaaaaaagacaaaaacatgtatgtgtttatatatggttTAATATATAAATCAGAATATTGAGTATAGttaatatatacacatgtatgttGGAGAGGCACAGGGTTACCTGCAGACATCAGGGTGTGTGAAGTATTAGGCCTCAGAGTTGGGATAGCTAAAGGGAGTTCAGTAAACAGCAGACTGCAGCATTTTCTGGCGTGAAAAATGGCCTTTACTTGTGTTGCTTCGGTACATTTTGTTATTGAgtgtgtgatttttcttttttttggtctGTCTAGTTGCATGTCGGTCCCCTCAGCGCAGTTACCAGTTTTAGAAATACCGCTCAGCCCAAAGTGACCCGTTCTCCGATTGACCTTGACCTCCAGGGTACTGTGGGatctttatttcttttaaaagcgTGGTGGCTGGCTGGCATCGAAATTGGGCTCTCCGTCAGCCTTGTTACATCTTTGTAGCATTACTGTAAGTGTACTGTACCATGAAATTCACTTCCCAAATGTTTTAGGACAGCCAGTCCTTCAAAGTTTCCAATTGGAATGCGCTGATGAAGGGTACACGCATCTGATGTCAGGGGACACGTAACCTGTTTGCTCTAATCTGAATGTGTCATTAATATGATGGTCTCCGACAGACTTTTGTGAAGTAGCGTGTTTACTAAAGATAGTGTTCTCTAACAGATTAAGGTGCGAGAGGTTGGAGACAAAGTGAAACTGCTTagtacaacaacaaaacacaaaaaaaaa

Function

GO:

id name namespace
GO:0060216 definitive hemopoiesis biological_process
GO:0016567 protein ubiquitination biological_process
GO:0023051 regulation of signaling biological_process
GO:0007165 signal transduction biological_process
GO:0007166 cell surface receptor signaling pathway biological_process
GO:0007175 negative regulation of epidermal growth factor-activated receptor activity biological_process
GO:0045121 membrane raft cellular_component
GO:0005886 plasma membrane cellular_component
GO:0030971 receptor tyrosine kinase binding molecular_function
GO:0016740 transferase activity molecular_function
GO:0005509 calcium ion binding molecular_function
GO:0046872 metal ion binding molecular_function
GO:0001784 phosphotyrosine residue binding molecular_function
GO:0004842 ubiquitin-protein transferase activity molecular_function
GO:0047690 aspartyltransferase activity molecular_function
GO:0017124 SH3 domain binding molecular_function
GO:0061630 ubiquitin protein ligase activity molecular_function

KEGG:

id description
ko04120 Ubiquitin mediated proteolysis
ko04012 ErbB signaling pathway
ko04144 Endocytosis
ko04910 Insulin signaling pathway
ko05200 Pathways in cancer
ko05205 Proteoglycans in cancer
ko05220 Chronic myeloid leukemia
ko05100 Bacterial invasion of epithelial cells
ko03000 Transcription factors
ko04131 Membrane trafficking
ko04121 Ubiquitin system

ZFIN:

id description
ZDB-GENE-041114-207 Predicted to enable SH3 domain binding activity; receptor tyrosine kinase binding activity; and ubiquitin protein ligase activity. Acts upstream of or within definitive hemopoiesis. Predicted to be located in cytoplasm. Predicted to be active in membrane raft and plasma membrane. Used to study myeloproliferative neoplasm. Human ortholog(s) of this gene implicated in acute myeloid leukemia; juvenile myelomonocytic leukemia; lung non-small cell carcinoma; and myeloid neoplasm. Orthologous to human CBL (Cbl proto-oncogene).

Ensembl:

ensembl_id ENSDART00000006085

JBrowse2

Neighbor

RNA id RNA type direction distance location representative gene id
TCONS_00018954 lncRNA upstream 578 23207159 ~ 23207464 (+) True XLOC_008490
TCONS_00018953 lncRNA upstream 646905 22541364 ~ 22561137 (+) True XLOC_008488
TCONS_00018952 lncRNA upstream 649070 22541364 ~ 22558972 (+) False XLOC_008488
TCONS_00018951 lncRNA upstream 657014 22541344 ~ 22551028 (+) False XLOC_008488
TCONS_00018949 lncRNA upstream 841520 22351365 ~ 22366522 (+) False XLOC_008483
TCONS_00018955 lncRNA downstream 1253 23266658 ~ 23268377 (+) True XLOC_008492
TCONS_00016992 lncRNA downstream 178269 23443674 ~ 23445988 (+) False XLOC_008495
TCONS_00018956 lncRNA downstream 202579 23467984 ~ 23505657 (+) True XLOC_008496
TCONS_00016998 lncRNA downstream 262782 23528187 ~ 23529174 (+) False XLOC_008497
TCONS_00017009 lncRNA downstream 519454 23784859 ~ 23789828 (+) False XLOC_008501
TCONS_00016985 mRNA upstream 19148 22722684 ~ 23188894 (+) False XLOC_008489
TCONS_00016987 mRNA upstream 20460 22867174 ~ 23187582 (+) True XLOC_008489
TCONS_00016983 mRNA upstream 669199 22448456 ~ 22538843 (+) False XLOC_008487
TCONS_00016982 mRNA upstream 669199 22448456 ~ 22538843 (+) False XLOC_008487
TCONS_00016981 mRNA upstream 669199 22448456 ~ 22538843 (+) True XLOC_008487
TCONS_00016989 mRNA downstream 91195 23356600 ~ 23358807 (+) True XLOC_008493
TCONS_00016991 mRNA downstream 178260 23443665 ~ 23451449 (+) False XLOC_008495
TCONS_00016995 mRNA downstream 257932 23523337 ~ 23528714 (+) False XLOC_008497
TCONS_00016994 mRNA downstream 257932 23523337 ~ 23528714 (+) False XLOC_008497
TCONS_00016996 mRNA downstream 257940 23523345 ~ 23527716 (+) False XLOC_008497
TCONS_00016984 other upstream 445604 22722682 ~ 22762438 (+) False XLOC_008489
TCONS_00016986 other upstream 475009 22722712 ~ 22733033 (+) False XLOC_008489
TCONS_00016979 other upstream 793789 22414124 ~ 22414253 (+) True XLOC_008485
TCONS_00016972 other upstream 1204846 22003082 ~ 22003196 (+) True XLOC_008478
TCONS_00016964 other upstream 1438033 21767524 ~ 21770009 (+) True XLOC_008473
TCONS_00016990 other downstream 112666 23378071 ~ 23378188 (+) True XLOC_008494
TCONS_00016993 other downstream 180784 23446189 ~ 23450686 (+) True XLOC_008495
TCONS_00017027 other downstream 1298363 24563768 ~ 24569062 (+) False XLOC_008513
TCONS_00017035 other downstream 1411508 24676913 ~ 24683290 (+) False XLOC_008517
TCONS_00017050 other downstream 1696731 24962136 ~ 24962252 (+) True XLOC_008523

Expression Profile

//

Homologous

species RNA id representative length rna type GC content exon number chromosome id location
grasscarp (Ctenopharyngodon idella) CI01000072_03455112_03462887.mRNA True 2481 mRNA 0.54 12 CI01000072 3454671 ~ 3462887 (-)
bowfin (Amia calva) AMCG00004460 True 2331 mRNA 0.61 14 CM030121.1 50144710 ~ 50157745 (-)