CI01000057_04612115_04631293 (RAF1, RAF1B)


Basic Information

Item Value
gene id CI01000057_04612115_04631293
gene name RAF1, RAF1B
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000057
NCBI id null
chromosome length 6014843
location 4611854 ~ 4631871 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000057_04612115_04631293.mRNA
GTTTATAAAGCGTACGTCTGCTGTTTTGAAGGATTATTGCTGCTAGTCACGTAGTCACATTATAAACACAATACCCACTTCAGAGTGGCTGGGACTAAATGAGAGCAATGGAAGTAGGAAATATTAACCGTATATCATGTTTCATGTGTGTACAGTTTGGGCCTCATCTCTGACCTCAGGTCAGTATGTTTGTGAGGTCGGGTCAGTTATATTTCTTCTGTTCTTATGCTAGATTATTGAAGTCCGCCGCTGCCTGCCGGGATGGAGCATGTTCAAGGGGCCTGGAAAAGCGTCAGTCATGGGTTTGGATGCAAAGACTCGGTGTTTGAAGATTCCTGCATGTCTCCCACCATTCTCAAGAACTTCCCGTACCGGAGATTGTCAGATGATGGGAGAATCACAGACTCTAAAACTAGCAGCACAATCCGTGTCTTCCTACCCAACAAACAGCGGACTGTGGTGAATGTGCGACCGGGTATGACGCTGCGCAACTGCCTCATCAAAGCCCTGAAAGTCCGTGGACTTCAGCCCGAATGCTGTGCCGTTTTCAAGCTTCTTCGAGAGCCTACCAGTTCCCACAGTAAGAAGAAGCGTATGGATTGGAGCACTGATTGTACCACACTGGTGGGAGAGGAGATGCTGGTCGAAGTCTTAGATCACGTCCCGCTGACCACGCACAATTTTGTACGAAAGACATTTTTGAAGTTGGCCTTTTGTGACATATGTCAGAAGTTTCTTTTACATGGCTTCAGATGTCAGACGTGCGGCTACAAATTTCACGAGCACTGCAGCACCAAAGTGCCCACCATGTGTGTGGACTGGAGCAACATTCGACAGCTCCTGCTGTTCCCGACTCCCGGAGAGAACGGCACTCCGTCACTCCCGCCCCTCTCGTCCCGTCGGATGCAAAACTCTAAATTCTCCTTCAGATACTCCACGCCGAATGCTTTAAACTACATCACTCCCATGCCGTCCGCTGGCGTCTCTCTCAGTCATAAAGTGTTGTCCACATCCACGCCCAATGTCCACATGGTGAGCACCACACAGCCGGTCGATGAGGCTGCTTATCAGGAAGCCTTAGGGCGTGATGAATCAGGAAGCCCTCAAAATCTGAGCCCGACCGAGTGGTCCAAAACCCCGGCTCCGGCTCACCGAGAGAAAGCGCCTTCAACCAACACTCAGGAAAAAAGAATCCGTCCACGAGAGAAGAGAGATTCCAACTACTACTGGGAGATCAAGACCACCGAGGTGATTCTGCTCTCCAGGATCGGCTCAGGCTCGTTCGGCACCGTCTACAAAGGGAAGTGGCACGGTGATGTTGCTGTGAAGATTTTAAAGGTGACGGATCCCACACCAGAGCAGTTACAGGCCTTTCGCAATGAAGTGGCTGTTCTCAGGAAAACCAGGCACGTCAATATTGTTTTGTTTATGGGATACATGACGAAGGAAAACCTGGCCATTGTGACGCAGTGGTGTGAAGGAAGTAGCCTCTACAAACATCTGCACGTGCAAGAGACGGACTTCCAGATGTTTCAGCTGATCGACATTGCCAGGCAGACGGCTCAGGGCATGGATTACCTACATGCAAAGAATATCATCCATCGAGACATGAAGTCAAACAGTATCTTTTACCATTGTGTCCATTTTACATCCTCTTATTTCTGTAACTTTGGTTACGATGTGAAAAGCAGCTTATTTTTGAAGCCTGTTGCAATATATATCTTCCTGCATGAAGGACTGACGGTGAAGATCGGTGATTTCGGTCTGGCCACAGTCAAAGCACGCTGGAGCGGCTCTTATCGGGTGGAGCAGCCGTCGGGATCCGTCCTCTGGATGGCTCCCGAGGTCATCCGGATGCAGGACAACAACCCGTACAGTTTTCAGTCAGATGTGTACTCGTACGGTATCGTCCTGTATGAGCTGATGACAGGAGAATTGCCTTATTCTATGGTTGCAAATAGAGATCAGATCATCTTTATGGTGGGTAGAGGTTATCTGACCCCTGACCTCAGTAAACTGTATAAGAGCTGTCCTAAAGCTATGAAGAGGCTCGTCGCTGACTGCATCCAGAAGTCCAAAGACGACAGACCGCTGTTTCCACAGATCCTGTCCTCGATCGAGCTGCTCCAGCACTCGCTCCCCAAAATCAACCGCAGCGCGTCCGAGCCGTCGCTCCACAGAGCCTCGCACACCGAGGACATCAACGTCTGCACTCTCGCGCTTTCATCCGCCTTCAAGTGAAGCGTCACGCTCGCTTCAGCCCAGGACACGCTAGCATCCAGTCGGCAAACATACTCCAGCTAGCGGCGGACACAGTGTTGGTCATTTATGTGCTTCGTCTAATATATTCTGTGTGTTAAGTCAAGAGTTTCAGTTGATCTCTCTTCCCGTCTGCCAGGAGGGAACAGCCAATCGCACTTTCTTTACACGGTTCACCTGTTGTGTCTAGCTGTATGGCAAAGTTTGAGTGGGAAATACCCAGAATAATCACGCGAACTGCCGCTTTCTCATGAATCCTACAATCACGTGTGGCTGAAATGACGTGTAAATATTCCCTAAGTGCCAGTGCCGCGGACGGCCGTGTGTCGAATGTGTGTTTTTATCAGCCGTACAGGGAGCACTTCATGATCACGTGTCTCGTTGTCTCTTTGACTTTGAGTATGTTACAAAAATCAAAGAAGAGTGGGTATTAACTTTATTATAAAACTTGTTAGGGATTCGTTTTTTTTTTTTTTTTTTGTGTTTTTTTTCAGCTTGTTACTGCTTGTCATGGAGAATTAACTTGTAAACTTGACAGATTGTTTATGCATTGTATTTTA

Function

symbol description
raf1b Predicted to enable protein kinase activity. Predicted to act upstream of or within intracellular signal transduction and protein phosphorylation. Predicted to be active in cytosol; mitochondrion; and plasma membrane. Human ortholog(s) of this gene implicated in Noonan syndrome (multiple); Noonan syndrome with multiple lentigines 2; adenocarcinoma (multiple); and dilated cardiomyopathy 1NN. Orthologous to human RAF1 (Raf-1 proto-oncogene, serine/threonine kinase).
raf1 Enables enzyme binding activity; identical protein binding activity; and protein serine/threonine kinase activity. Involved in several processes, including activation of adenylate cyclase activity; positive regulation of MAPK cascade; and positive regulation of peptidyl-serine phosphorylation. Located in Golgi apparatus; cytosol; and nuclear speck. Colocalizes with plasma membrane. Implicated in Noonan syndrome (multiple); Noonan syndrome with multiple lentigines 2; adenocarcinoma (multiple); and dilated cardiomyopathy 1NN. Biomarker of colorectal adenocarcinoma; colorectal adenoma; and prostate cancer.

GO:

id name namespace
GO:0006468 protein phosphorylation biological_process

KEGG:

id description
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000057_04612115_04631293.mRNA True 2819 mRNA 0.48 16 4611854 4631871

Neighbor

gene id symbol gene type direction distance location
CI01000057_04601541_04604168 NA coding upstream 7435 4601170 ~ 4604419 (+)
CI01000057_04547933_04555967 RAB43 coding upstream 55866 4547757 ~ 4555988 (+)
CI01000057_04491831_04508031 CRTC1 coding upstream 103319 4491831 ~ 4508535 (+)
CI01000057_04473417_04481843 KLHL26 coding upstream 129960 4473222 ~ 4481894 (+)
CI01000057_04443549_04450402 RAB3A, RAB3A.L, RAB3AB coding upstream 160716 4443549 ~ 4451138 (+)
CI01000057_04644947_04646881 NA coding downstream 13076 4644947 ~ 4647013 (+)
CI01000057_04684204_04698051 METTL1, METTL1-B coding downstream 52333 4684204 ~ 4698051 (+)
CI01000057_04703416_04711776 CYP27B1 coding downstream 71482 4703353 ~ 4711933 (+)
CI01000057_04737652_04740503 METTL21B coding downstream 105781 4737652 ~ 4740981 (+)
CI01000057_04755505_04764341 NA coding downstream 123634 4755505 ~ 4764412 (+)
G245644 NA non-coding upstream 13443 4597952 ~ 4598411 (+)
G245464 NA non-coding upstream 28592 4580465 ~ 4583262 (+)
G245457 NA non-coding upstream 54841 4556709 ~ 4557013 (+)
G245479 NA non-coding upstream 125748 4485283 ~ 4486106 (+)
G245467 NA non-coding upstream 153995 4455149 ~ 4457859 (+)
G245652 NA non-coding downstream 21536 4653407 ~ 4653646 (+)
G245653 NA non-coding downstream 21912 4653783 ~ 4654019 (+)
G245654 NA non-coding downstream 22969 4654840 ~ 4655351 (+)
G245483 NA non-coding downstream 67633 4699504 ~ 4702148 (+)
G245671 NA non-coding downstream 117936 4749807 ~ 4750059 (+)
G245486 NA other upstream 399773 4209897 ~ 4212081 (+)
CI01000057_03842028_03844033 NDUFS7.S, MGC85267, NDUFS7 other upstream 767163 3842028 ~ 3844691 (+)
G245401 NA other upstream 1073412 3537569 ~ 3538442 (+)
G245231 NA other upstream 1319292 3087096 ~ 3292562 (+)
G243991 NA other upstream 1959294 2635237 ~ 2652560 (+)
G245725 NA other downstream 466814 5098685 ~ 5103606 (+)
CI01000057_05564489_05579041 NA other downstream 942033 5564489 ~ 5579843 (+)
G245856 NA other downstream 1005783 5637654 ~ 5643340 (+)
G245857 NA other downstream 1023405 5655276 ~ 5657239 (+)
CI01000057_05912175_05916639 NA other downstream 1279942 5911767 ~ 5917211 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location