XLOC_012862 (mvda)


Basic Information

Item Value
gene id XLOC_012862
gene name mvda
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007129.7
NCBI id CM002902.2
chromosome length 51023478
location 31056645 ~ 31068755 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00025669
TTTTAACAAGGTTAGTAGTCGATCACACTATGCTTAAcaagaaattaaaattaataaataaacacccAACATGACTGAATGTGGAGTTGTGTGAGGAATCTGTAGCAGGTCATAGTGAAAGACAAAACAATGAAGAAGGAAACTAGGAAAGTGTGAGAGGAAGAAGACACATATTATCATTTATGGAACAACGTGTTAATTCCGTTTTGTTAGTAGTACTATATTAATATgagtatttaataattatttttttacaatacgcGTCTGGTTATTCCTACACAGTAGGTGGCGATAATACGCTTTAAACGTTGGTTTTATCCGTTATAAAACCGAGGAATAAGAAGTAAGACCATTGTGGTCCGACGCCAGTTATTGGTTCATTTTCCATAGTGTTGTACGGTGAAGTCTTCAATTGGTCAAACACCGAACCTCGTGTTCATCAAGAGCCAATCCCAATCCGCTTTGCTGTGCTTATTTGGTTTCAGTGTTTAAACAAGCAAAGAGTAGTTTGCGATCAGTGGAAGTCTGTTTGGAAGTAtgtttgttgtcatttaaaaaatatataacattttatcattattattttttgtacaaaATTATAAATACGAAAATGTCGGAAAATATTCTCCAAGATCTTGAAATGGTCACCTGCACCGCACCGGTAAACATTGCGGTCATCAAATACTGGGGTAAACGTGATGAAGATCTCATTCTGCCAGTCAATGCATCCCTCAGTGTGACGCTGCATCAAGATCACCTCAGAACAACTACAACAATTGCATGCAGCAGAAGTTTTCATAAAGACTGCATTTGGCTGAATGGCAAAGAACAGGATATCAGTCATCCAAGGTTGCAGTCGTGTTTGCTGGAAAtcCGTAGATTGGCtcaaagaagaaaaaatactggAGATCCCGCTTCTGATGTCAGCAACAAGGTCCATATCTGTTCTGTGAATAATTTCCCCACTGCTGCTGGCCTGGCATCATCTGCAGCAGGCTATGCCTGTTTAGTCTACACACTGTCCCAGTTGTTTAATGTGGAGGGTGAGCTGTCTGGAGTGACGCGACAGGGCTCTGGCAGTGCCTGCAGGAGTTTGTATGGTGGCTTCGTTCAGTGGAAGTTGGGGGAGCGATCAGATGGAAAAGACAGTATTGCTGAACAAGTGGCATCTGAGTTGTACTGGCCAGAGCTCAGAGTATTGATTCTTGTGGTCAGTGCTGAGCAGAAATCTGTTGGCAGCACATCTGGAATGCACACAAGTGTGGAGACGAGCCACCTTCTGAAGTACAGAGCAGATGCTGTGGTCCCCGGTCGTATGGAAGAGATGATAAGGGCAATTCACCTACGAGACTTTCCAAAATTTGGTGAGCTGACCATGAAAGACAGTAATCAGTTTCATGCCATCTGCCTGGACACCTACCCACCTATATTCTACCTGAACAACATATCGCACCAGATCATCAGTCTTGTACACCGCTACAACCAGTACTATGGCGAGACCAGGGTGGCATATACCTTTGATGCTGGTCCTAATGCAGTTATTTACTCCTTGCAAGACTACTTACCAGAGTTTGTAGAGGTGGTTCGCCATTTCTTTCCCCCTAAGGTCAATGAAGAAGAATTTTTCAAAGGTCTACCAGTGTGCACAGCTGACCTCTCTGAGGAGATGATAAGAGACATCAATATGAAACCAACCCCCAATGGAATACGCTATATAATCAGCACTAAAGCTGGCCCTGGACCACGTGTGGTGGAAGATCCAAACCTTCATTTGCTGGGTGCTGATGGCCTGCCCAAGAAGATTGCAGTTTAA
>TCONS_00025670
AAAGAGTAGTTTGCGATCAGTGGAAGTCTGTTTGGAAGTAtgtttgttgtcatttaaaaaatatataacattttatcattattattttttgtacaaaATTATAAATACGAAAATGTCGGAAAATATTCTCCAAGATCTTGAAATGGTCACCTGCACCGCACCGGTAAACATTGCGGTCATCAAATACTGGGGTAAACGTGATGAAGATCTCATTCTGCCAGTCAATGCATCCCTCAGTGTGACGCTGCATCAAGATCACCTCAGAACAACTACAACAATTGCATGCAGCAGAAGTTTTCATAAAGACTGCATTTGGCTGAATGGCAAAGAACAGGATATCAGTCATCCAAGGTTGCAGTCGTGTTTGCTGGAAAtcCGTAGATTGGCtcaaagaagaaaaaatactggAGATCCCGCTTCTGATGTCAGCAACAAGGTCCATATCTGTTCTGTGAATAATTTCCCCACTGCTGCTGGCCTGGCATCATCTGCAGCAGGCTATGCCTGTTTAGTCTACACACTGTCCCAGTTGTTTAATGTGGAGGGTGAGCTGTCTGGAGTGACGCGACAGGGCTCTGGCAGTGCCTGCAGGAGTTTGTATGGTGGCTTCGTTCAGTGGAAGTTGGGGGAGCGATCAGATGGAAAAGACAGTATTGCTGAACAAGTGGCATCTGAGTTGTACTGGCCAGAGCTCAGAGTATTGATTCTTGTGGTCAGTGCTGAGCAGAAATCTGTTGGCAGCACATCTGGAATGCACACAAGTGTGGAGACGAGCCACCTTCTGAAGTACAGAGCAGATGCTGTGGTCCCCGGTCGTATGGAAGAGATGATAAGGGCAATTCACCTACGAGACTTTCCAAAATTTGGTGAGCTGACCATGAAAGACAGTAATCAGTTTCATGCCATCTGCCTGGACACCTACCCACCTATATTCTACCTGAACAACATATCGCACCAGATCATCAGTCTTGTACACCGCTACAACCAGTACTATGGCGAGACCAGGGTGGCATATACCTTTGATGCTGGTCCTAATGCAGTTATTTACTCCTTGCAAGACTACTTACCAGAGTTTGTAGAGGTGGTTCGCCATTTCTTTCCCCCTAAGGTCAATGAAGAAGAATTTTTCAAAGGTCTACCAGTGTGCACAGCTGACCTCTCTGAGGAGATGATAAG

Function

symbol description
mvda Predicted to enable diphosphomevalonate decarboxylase activity. Predicted to be involved in isopentenyl diphosphate biosynthetic process, mevalonate pathway. Predicted to act upstream of or within cholesterol biosynthetic process and isoprenoid biosynthetic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in porokeratosis. Orthologous to human MVD (mevalonate diphosphate decarboxylase).

GO:

id name namespace
GO:0006629 lipid metabolic process biological_process
GO:0016126 sterol biosynthetic process biological_process
GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway biological_process
GO:0008202 steroid metabolic process biological_process
GO:0008203 cholesterol metabolic process biological_process
GO:0006694 steroid biosynthetic process biological_process
GO:0006695 cholesterol biosynthetic process biological_process
GO:0008299 isoprenoid biosynthetic process biological_process
GO:0005829 cytosol cellular_component
GO:0005737 cytoplasm cellular_component
GO:0004163 diphosphomevalonate decarboxylase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0016829 lyase activity molecular_function
GO:0016831 carboxy-lyase activity molecular_function
GO:0000166 nucleotide binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-041114-127 Predicted to enable diphosphomevalonate decarboxylase activity. Predicted to be involved in isopentenyl diphosphate biosynthetic process, mevalonate pathway. Predicted to act upstream of or within cholesterol biosynthetic process and isoprenoid biosynthetic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in porokeratosis. Orthologous to human MVD (mevalonate diphosphate decarboxylase).

Ensembl:

ensembl_id ENSDARG00000099336

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00025669 False 1813 mRNA 0.42 10 31056645 31068755
TCONS_00025670 True 1176 mRNA 0.45 9 31057143 31068420

Neighbor

gene id symbol gene type direction distance location
XLOC_012861 cd151l coding upstream 33198 30998472 ~ 31023447 (+)
XLOC_012860 mthfsd coding upstream 104363 30878196 ~ 30952282 (+)
XLOC_012859 foxf1 coding upstream 206280 30847237 ~ 30850365 (+)
XLOC_012858 irf8 coding upstream 482796 30567945 ~ 30573849 (+)
XLOC_012857 dusp22a coding upstream 491957 30511230 ~ 30564688 (+)
XLOC_012863 NA coding downstream 4488 31073243 ~ 31075619 (+)
XLOC_012864 tcf25 coding downstream 48381 31117136 ~ 31206658 (+)
XLOC_012865 NA coding downstream 212095 31280850 ~ 31459487 (+)
XLOC_012866 NA coding downstream 450823 31519578 ~ 31521691 (+)
XLOC_012867 dhx36 coding downstream 541989 31610744 ~ 31837760 (+)
XLOC_012854 NA non-coding upstream 924814 30129771 ~ 30131831 (+)
XLOC_012849 CT025546.2 non-coding upstream 1881437 29175093 ~ 29175208 (+)
XLOC_012845 CR769777.2 non-coding upstream 2752328 28303891 ~ 28304317 (+)
XLOC_012841 BX649600.1 non-coding upstream 3319805 27736724 ~ 27736840 (+)
XLOC_012835 BX640463.2 non-coding upstream 3860319 27196210 ~ 27196326 (+)
XLOC_012868 BX908763.1 non-coding downstream 776749 31845504 ~ 31846556 (+)
XLOC_012869 NA non-coding downstream 803266 31872021 ~ 31872676 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000359_00240563_00291074 MVDA, MVD coding CI01000359 null 240563 ~ 291074 (+)