CI01180000_02690045_02691641 (NKX6-2, NKX6-2.L, NKX6.2)


Basic Information

Item Value
gene id CI01180000_02690045_02691641
gene name NKX6-2, NKX6-2.L, NKX6.2
gene type misc
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01180000
NCBI id null
chromosome length 11503085
location 2689271 ~ 2693221 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01180000_02690045_02691641.mRNA
CCTACAAAAACACCTCACGATGAATCTGAGTTACAAGCTCTTATGTCTTAAACCGAGCGGAAGTTTTAATAACCTGCGATAATCGAATCGTTTTCGCGTTTTATCTTACGCGCGATGAGATCGCGTTTTCCGCACTTAATTATCGTTAAATATTTGTTCTAAACGAAACGGAAGATGGACTAATCAAATGACCCTTACGTACGGCTTTTAATATCATTAGCGACACAGTTGTATGAGGTTAATGTACTTACTCTGCCAGCGTCATAAAGTAAACGCGTCTATTGTGTCAAATGTTGAAACAATGATTTCTACAGTGCGACGCGTCATTAATGGCGCTACAATACGAGCTTGATGGAGTGCGGCTTTGTCCCGGCTACGCGTATGCAAATTCGCCGCCGCGCATCCTCCAATCAGAGAATAGCGTCACTTAGCGTCTTCCAATAGGAGATACGCGCTTGCAGGTGGCGGTGCGGTTATCTGCTCGTCATCACAGATAGAGTCCATTGACCGGCGAACGGCGCCTCAGATGCGGGGGATCGCAGCACTCAAAGCGGGCGTGAGATCTGCCGACGGCCGGCGGCTGGATTCTGCTTCGGAAACTCCCACAGCCTGAAGGACACTTTTGCATGGGAAACATTCGCAAAACTTTTGAAACTTGCAATTCTCGTTCCCTTGGATGAGTTGTCAAGTTGTGGGCACTAAACTTTGTCGTGCACTGTTGTACTTTGTATGTCTGTTGTTGTTTGGCGGTTCATCCTGTGGTTCACGCGCACCAATGTTAGCTGTCGGGCAGATGGATACTAACCGGCAGAGTGCGTTCGTTCTGGGCAGCACTCCACTGGCTGCGCTGCACAACATGACCGAGATGAAGACCTCTTTATTCCCGTACACCCTGCAGAACCCCGCGGGCTTCAAGGCTCACTCCCTCGGCAACCTGAACTCTCAGATTCCCCTCGGAACGCCGCATGGAATAAGCGATATCTTGGGGAGACCCATCACCACCGCCGGACAGCTGCTCTCGGGCTTTCCCAGGATCAACGGGTTGGCCACATCAGCTGGGATGTACTTCAACCCGGCGGCCGTGTCTCGGTATCCCAAACCCCTGACGGAGTTGCCCGGTAGGGCGCCCATATTCTGGCCGGGAATGATGCAAGGTTCACCCTGGCGAGACCCGCGGGTTCCCTGTCCGGCCCAGGCGAATATGATGCTGGACAAGGATGGCAAGAAGAAACATTCCAGACCAACTTTTTCAGGACAGCAGATTTTCGCGCTGGAGAAAACCTTCGAACAGACCAAATATCTGGCCGGTCCAGAGAGAGCAAGACTCGCATATTCTCTGGGAATGACCGAAAGTCAAGTCAAGGTTTGGTTTCAGAACAGAAGAACCAAATGGCGGAAGAGACACGCGGCTGAAATGGCCACGGCTAAAAAGAAACACGATTCAGAGACGGAGAAAATGAAGGAAAGCTCGGAAAACGAGGAGGATGATGAATATAACAAACCTCTGGACCCGAACTCCGACGACGAGAAAATCACAAGACTGTTGAAAAAGCACAAGACGAGTAACCTGTCCCTCATCAGCCCGTGCAGTAACAGCTCGGACACTTTGTGATGATACTGAGCAAAAGACTCTTCATTATCATCATCATCATCTGCCTCAGATTCTTCTGGGAAAATGAGACAGAGTTAAGCAGGGTATAAACACACTGTTCACGCTGCTTTTGCTTTGCTTTGAATGCGGTTGTACAGTTAGAAGTGGACGTGAGATGTATATATATTTTTTACTGAGTAAATTATGTTATGAAAGCATCACGAAGACGTGCCAACTTTCCCTCATCATCATCATCATCATCACCACCACCATTTAAGATCATCTTTGTCTTCGATCGCAGAAGAATAACGACGCATATTTCGCCTAAAAGTTTCACTTTTTTAATTTTGAAAACAGGTACACAAAGTGTATAAAAGTGCCAGTGCTGTAAATGATGTGAATAGAATTTGTTTTAACAATGTCCTTTTGGCCGCTTATACTTTCAATGGAAGGAGTTTATGTTTTACCTCACAACACGAAAAATACACAAAGATGGACATAAATATCGATGAAGAGAATATTATTGCTTCCGTGATGAAGGAAGAAAAAACTTTGTATTATC

Function

symbol description
nkx6.2 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within pancreatic A cell differentiation; spinal cord motor neuron differentiation; and type B pancreatic cell differentiation. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; endoderm; neural plate; neuroectoderm; and pancreatic system. Human ortholog(s) of this gene implicated in spastic ataxia 8. Orthologous to human NKX6-2 (NK6 homeobox 2).
nkx6-2 Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in cell differentiation; regulation of myelination; and regulation of transcription, DNA-templated. Predicted to act upstream of or within several processes, including negative regulation of transcription by RNA polymerase II; neurogenesis; and neuromuscular process controlling balance. Predicted to be part of chromatin. Predicted to be active in nucleus. Implicated in spastic ataxia 8.

GO:

id name namespace
GO:0043565 sequence-specific DNA binding molecular_function

KEGG:

id description
K09350 NKX6-2; homeobox protein Nkx-6.2

RNA

RNA id representative length rna type GC content exon number start site end site
CI01180000_02690045_02691641.mRNA False 2153 mRNA 0.47 3 2689271 2692183

Neighbor

gene id symbol gene type direction distance location
CI01180000_02613130_02639905 NA coding upstream 49349 2612278 ~ 2639922 (+)
CI01180000_02574027_02588521 NA coding upstream 100447 2574027 ~ 2588824 (+)
CI01180000_02541296_02567509 CFAP46 coding upstream 121488 2541296 ~ 2567783 (+)
CI01180000_02362001_02362428 NA coding upstream 325741 2361960 ~ 2363530 (+)
CI01180000_02322594_02323609 NA coding upstream 365519 2320352 ~ 2323752 (+)
CI01180000_02951792_02968343 STK32C coding downstream 259609 2951792 ~ 2968343 (+)
CI01180000_02998131_03010201 NA coding downstream 305948 2998131 ~ 3010503 (+)
CI01180000_03077007_03078238 NA coding downstream 384424 3076607 ~ 3078799 (+)
CI01180000_03149731_03154047 NA coding downstream 456864 3149047 ~ 3154088 (+)
CI01180000_03210894_03214195 LBH coding downstream 518711 3210894 ~ 3214720 (+)
G680204 NA non-coding upstream 5691 2683234 ~ 2683580 (+)
G680180 NA non-coding upstream 25026 2635775 ~ 2664245 (+)
G680148 NA non-coding upstream 116532 2572412 ~ 2572739 (+)
G679346 NA non-coding upstream 246700 2442275 ~ 2442571 (+)
G679047 NA non-coding upstream 447398 2238490 ~ 2241873 (+)
CI01180000_02690045_02691641 NKX6-2, NKX6-2.L, NKX6.2 non-coding downstream 1314 2689271 ~ 2693221 (+)
G680227 NA non-coding downstream 46534 2738717 ~ 2739535 (+)
G680239 NA non-coding downstream 71839 2764022 ~ 2764255 (+)
G680241 NA non-coding downstream 76241 2768424 ~ 2769025 (+)
G680242 NA non-coding downstream 78605 2770788 ~ 2771029 (+)
G679324 NA other upstream 291911 2388867 ~ 2397360 (+)
G679076 NA other upstream 889838 1795170 ~ 1799433 (+)
G678946 NA other upstream 1133120 1518353 ~ 1612547 (+)
G678637 NA other upstream 1533599 1149551 ~ 1155672 (+)
G678751 NA other upstream 1623180 1059843 ~ 1066091 (+)
CI01180000_03571292_03571611 GNG2.L, GBG2, GNG2 other downstream 861094 3569165 ~ 3573135 (+)
G680736 NA other downstream 1073508 3765691 ~ 3784441 (+)
G681137 NA other downstream 2091122 4783305 ~ 4785631 (+)
G681268 NA other downstream 2678227 5370410 ~ 5373762 (+)
G681592 NA other downstream 3780852 6471995 ~ 6478999 (+)
G680263 NA non-coding downstream 110225 2805661 ~ 2806462 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_006297 nkx6.2 coding NC_007124.7 CM002897.2 51579851 ~ 51584264 (+)