XLOC_015435 (kcnh2a)


Basic Information

Item Value
gene id XLOC_015435
gene name kcnh2a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007113.7
NCBI id CM002886.2
chromosome length 59640629
location 24080694 ~ 24168670 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00030871
AAACACAGAGAGGGGCTGTTTCGCAGCGCGTCGGAGAAAGTGATTGAGTGAACTGGGACAGAAAGTTGATTTGCATCCATTTGCAAACAAAAAGGGAAGCAGGTGACGTGAGGTAATTGGAGAGACGGCTGATTTACTGAGCTCGAGGATGCGCGCACTGACAGATTTAACACGTAATCACTGGAGACTTTGAAGAGACGCGCTCTCGTGCTGCTTTTACATCGATGTGGTGTGAAGGTAAAGCTTGTGTACATGTGTAACACTTCGCGGTAGAGTCGATATATCGCTCTTATTCAAGTAAATACAAGCTGTCGAGGAACTTGCAGAACTTTCTTGCCCTGCTGTGGTAGGACAACATGCCTGTACGACGGGGACACgttgcgcctcagaacacctttcTGGACACCATCATTCGCAAATTCGAGGGTCAAAATCGCAAATTCATCATCGCCAATGCTCGAGTTGAAAACTGTGCCATCATCTTCTGTAATGATGGCTTTTGTGGGATGTGTGGCTACACGCGTTCAGAGGTCATGCAGAAACCGTGTACATGCAGTTTTCTGTATGGCCCACACACTGGACGACCAGCGGTGGCCCAGATGGCCAAAGCCTTACTGGGCTCTGAAGAAAGGAAGGTGGAGATCTCCTTATACAGGAAAGATGGTGTGTGTTTGCCTTGCCTTGTGGACGTGGTTCCTGTTAAGAACGAGGACGGTTTAGTTATCATGTTTATCCTGAACTTTGAGCTGGCAGATCAGCAGGACAGACCCCTCGACAGCTCACCAGGCAGAGACATCAACAACAAAAACCCCATTCCGTGGCTCTCTAAAGCAAGACGACGTCGTCTCCGGCTGCCACTGCCCTTGCTGCACTCTCTGAGTGGCAGTAAACAGTCTCTGCATGAAGACACTGAAAAAGGCTTCATGCAGCCGATGCCTCATATGGGCCATGAGTCAGTAGCCCTGGACAAACTGCTCTCCCTACCTGAACGCTCAGCACTCGGAGGATCTCAGCTGTTGTTCTGGGAAGATAAGGCTCAGACTGAGTCTGAAAGTGAGCTGCGGCCATCAGAAGTGTCTCCTCCTCTGCCTCAGGGCTTCTCGCAGTCCTCCCCACGTCTGCACAACCTCACCTCAGAGGCGTCTCCGTCCAGTTGCAGCATGGCCCACAGCCGCTCCTGTGAGAGCCTGTGTGGCATGAGGCCCTCACCCTCCACCAATGACTTTAACTGGGACAGAAAACTGCCAGTCAGACCCAGTAGCACAGGTGCCATGCACCGCAAAGCCAGCTTACAGAATGCTACTTCTGACTCAGATCTCATTCGGCTCCGGAGCTCAGGTCGGGGCACCCAAATATCACACAACTTAATAGATATGAAGCCGGACGCATTAATTGCAGTCCCCACCGGTGAGATTGACATCATCGCCCCCTGCAAGCTGATCGACCGGACCCATAATGTGACAGAGAAGGTCACTCAGGTTCTGTCTCTGGGTGCAGATGTCCTTCCTGAGTATAAGCTCCAGGCTCCCCGCATCCACAAATGGACTATCTTACACTACAGCCCATTCAAGGCGGTCTGGGACTGGGTTATCCTGCTGCTGGTCATCTACACGGCCATCTTCACTCCTTATTCGGCTGCGTTCCTGCTTAGCGATGAGGAAGAAGAAGTCATTCAGCGCTGTGGATACTCCTGCAGTACACTCAATGTGGTGGACCTCATTGTAGACATCATGTTTGTAGTGGACATTGTGATTAACTTTCGTACAACCTACGTGAACAGTAACGATGAAGTGGTCAGTCAGCCCGGCCGGATCGCCGTCCACTATTTTAAAGGCTGGTTCCTCATTGACATGGTTGCTGCCATTCCCTTCGACTTGCTCATTTACCGCTCTGAAGAAGAGACCACGACATCCACAactctgattggcctgctgaaaACAGCTCGGTTGCTGCGATTGGTGCGTGTGGCACGCAAACTTGACCGCTACTCTGAGTATGGAGCTGCTGTTCTCTTTCTGCTCATGTGTACCTTTGCTCTGATCGCCCATTGGCTGGCCTGCATCTGGTATGCGATTGGGAACGTGGAGAGAAGCGGCCCATCTCGAATCGGTTGGCTTAATTCTTTGGGTGATCAGCTGGGAAAGCCATATAATTCATCAGTACGTGGATCAGGACCCTCTATTAAAGATAAATATGTCACTGCCCTGTACTTCACCTTCAGCAGCCTCACCAGCGTGGGCTTTGGAAACGTCTCCCCAAACACAAACTCAGAGAAGATCTTCTCCATCTGTGTGATGCTCATCGGAGCGCTAATGTATGCCAGCATATTTGGAAATGTGTCCGCCATCATCCAGAGACTATACTCTGGCACTGCGCGTTACCACACTCAGATGCTGCGGGTTCGAGAGTTTATCCGTTTCCATCAGATCCCCAACCCACTTCGGCAAAGACTAGAGGAGTATTTCCAGCATGCTTGGTCCTACACCAATGGCATTGACATGAATGCTGTGCTGAAGGGTTTTCCTGAGTGCTTACAGGCTGACATCTGTTTGCATCTGAATCGTACACTGCTGCAGAGCTGTAAAGCTTTCAAGGGTTCCTCCAAAGGCTGCTTGCGTGCTCTGGCTATGAAGTTTAAGACTACTCACGCTCCTCCAGGAGACACCTTGGTCCATGCTGGAGATGTGATTTCAGCGCTATACTTCATATCTCGGGGCTCCATCGAGATTTTAAAGGGAGATGTAGTTGTGGCTATTTTAGGCAAGAATGATATATTTGGAGAGCCCATTAACTCATATGCTCGTCCTGGAAAGTCAAGTGCAGATGTGAGAGCACTTACGTACTGTGACCTGCACAAAATCCACAGAGATGATGTCCTGGAGGTCTTGGAAATGTATCCAGAGTTCTCTGACTACTTTTGGAGCAATCTGGAAATCACTTTTAATTTGAGAGACACTAACACTAAAGCTGGGTCAATGAGCAGTGACCCTGATGATTCGGACAATGGCGGTCTGGACCATCACACACGCAGAGCAAAGTTGTTCTTTCAATCTAAAAGAAACTCCATCTCTCGAGATACAGAGAGAACAGAAGACAGGCTCAACAGGATGACTTTCAGAACACAGACTTCAGGAAAACAGCATGAGAACAGACAAACTGCTCATCGCAGCTCAGACATCTTTGCCTCACAGTCAAGCAGCGATGAAGAGGAAGAGACTCAACGACCCTCTGTGATGGTGGACTGCTCTCAGAGCCATATCAATAGCGTTAGCAATGCTAACAGGGACAAGGACCACAACAGCAGTAACTCGTTCAACGCACTCTCAGGAGCTTTTTCAGGGGTTTCTAACATCTTTAGCCTTTGGGGAGACAGCAGCCGTGGCCATCACTACCAGGAAGTACCCAGCCACAGCATGTCCTTCCCCTCATCTTCAGTTCCCTCTAACACCGTCCTGCACAATGTCACCTATGGGCAATGCTCAGAGGTAGAGAACAGACTGGAAATGATGCACAGGCAGCTCTACCGATTGGAGAAGCGCATGTCAAAGGACATTGGAGCCATAATGCAGTTGCTTCAGAGGCAAATGGTGCAGGTTCCACCAGCCTACAGCTCAGTGACGTCTCCTACAGAAGCATCGCCAATTCCACCCAAACCTGGACAGAAATTGGTTCAGCCTGTGAATCCTTTAGAAACAGAGACTCCATCTATCCTGTCTGAGatacTTGATCCTCATGACTTTGCTGACAGTCCTATTAAGGCCAGTGAAAGTCTGTCAGGTGCAATGGAGCTCCAGCTCCTGGACTGTTCCTCACAGCCTCCCTCTGAGAATCCTTCTGGGGCTTATATGGGGAGATGGTCACGTAGCGTAAGCCACCACACAAACACCACTGGTGATCCTACAGCACACATCCATCTCCAACAAACAGCCATAGCTGATCAAGCTCATTACAGCTTTTTGGATGCAGAGCCTATTGGAACTCTTCGCCAACCACAAGCTGTACAGAGTTTACATTTGGAGACCTCTGAGTGTTCAAGACGCCAATCGCTGCCAGTAAAACATCAGGTCGAAGATGATTGCTCAATGCAGAAAAGACATCCCTCTGATCCTGGCTCTTAAGACAAACTTGTTCGGTATCTCAGTGGAAAACAATGCAAAGACCACCAACATGTTGGCATGGTGTTTAAAAGACTATTCAGGATCATATATAATTACCTCAGAAAAACGGTCAAGGATGCATCATTATTGTCCCTGTAGGTTTGTACATTTGTGTTAGCTGGTTTAACAATATTCATTGTTTTTACCTGCCTCATTATGAAAGTGTTCTCATTGTTTTGAGgtgtaaatgtaatgatttgTATTAGCAtatcagctttttttttacaatgtggttTTGTGTTGAATTGATTAGCCTatactgtagatttttttttaataactgaaacACTGGAAAGGCCAATCAGAGCAGGATTTATTAGAGTTCAAATGATCATTTGGAAACTTTAGCCCCTTTCATACATACagactttttca
>TCONS_00030872
ATGCCTGTACGACGGGGACACgttgcgcctcagaacacctttcTGGACACCATCATTCGCAAATTCGAGGGTCAAAATCGCAAATTCATCATCGCCAATGCTCGAGTTGAAAACTGTGCCATCATCTTCTGTAATGATGGCTTTTGTGGGATGTGTGGCTACACGCGTTCAGAGGTCATGCAGAAACCGTGTACATGCAGTTTTCTGTATGGCCCACACACTGGACGACCAGCGGTGGCCCAGATGGCCAAAGCCTTACTGGGCTCTGAAGAAAGGAAGGTGGAGATCTCCTTATACAGGAAAGATGGTGTGTGTTTGCCTTGCCTTGTGGACGTGGTTCCTGTTAAGAACGAGGACGGTTTAGTTATCATGTTTATCCTGAACTTTGAGCTGGCAGATCAGCAGGACAGACCCCTCGACAGCTCACCAGGCAGAGACATCAACAACAAAAACCCCATTCCGTGGCTCTCTAAAGCAAGACGACGTCGTCTCCGGCTGCCACTGCCCTTGCTGCACTCTCTGAGTGGCAGTAAACAGTCTCTGCATGAAGACACTGAAAAAGGCTTCATGCAGCCGATGCCTCATATGGGCCATGAGTCAGTAGCCCTGGACAAACTGCTCTCCCTACCTGAACGCTCAGCACTCGGAGGATCTCAGCTGTTGTTCTGGGAAGATAAGGCTCAGACTGAGTCTGAAAGTGAGCTGCGGCCATCAGAAGTGTCTCCTCCTCTGCCTCAGGGCTTCTCGCAGTCCTCCCCACGTCTGCACAACCTCACCTCAGAGGCGTCTCCGTCCAGTTGCAGCATGGCCCACAGCCGCTCCTGTGAGAGCCTGTGTGGCATGAGGCCCTCACCCTCCACCAATGACTTTAACTGGGACAGAAAACTGCCAGTCAGACCCAGTAGCACAGGTGCCATGCACCGCAAAGCCAGCTTACAGAATGCTACTTCTGACTCAGATCTCATTCGGCTCCGGAGCTCAGGTCGGGGCACCCAAATATCACACAACTTAATAGATATGAAGCCGGACGCATTAATTGCAGTCCCCACCGGTGAGATTGACATCATCGCCCCCTGCAAGCTGATCGACCGGACCCATAATGTGACAGAGAAGGTCACTCAGGTTCTGTCTCTGGGTGCAGATGTCCTTCCTGAGTATAAGCTCCAGGCTCCCCGCATCCACAAATGGACTATCTTACACTACAGCCCATTCAAGGCGGTCTGGGACTGGGTTATCCTGCTGCTGGTCATCTACACGGCCATCTTCACTCCTTATTCGGCTGCGTTCCTGCTTAGCGATGAGGAAGAAGAAGTCATTCAGCGCTGTGGATACTCCTGCAGTACACTCAATGTGGTGGACCTCATTGTAGACATCATGTTTGTAGTGGACATTGTGATTAACTTTCGTACAACCTACGTGAACAGTAACGATGAAGTGGTCAGTCAGCCCGGCCGGATCGCCGTCCACTATTTTAAAGGCTGGTTCCTCATTGACATGGTTGCTGCCATTCCCTTCGACTTGCTCATTTACCGCTCTGAAGAAGAGACCACGACATCCACAactctgattggcctgctgaaaACAGCTCGGTTGCTGCGATTGGTGCGTGTGGCACGCAAACTTGACCGCTACTCTGAGTATGGAGCTGCTGTTCTCTTTCTGCTCATGTGTACCTTTGCTCTGATCGCCCATTGGCTGGCCTGCATCTGGTATGCGATTGGGAACGTGGAGAGAAGCGGCCCATCTCGAATCGGTTGGCTTAATTCTTTGGGTGATCAGCTGGGAAAGCCATATAATTCATCAGTACGTGGATCAGGACCCTCTATTAAAGATAAATATGTCACTGCCCTGTACTTCACCTTCAGCAGCCTCACCAGCGTGGGCTTTGGAAACGTCTCCCCAAACACAAACTCAGAGAAGATCTTCTCCATCTGTGTGATGCTCATCGGAGCGCTAATGTATGCCAGCATATTTGGAAATGTGTCCGCCATCATCCAGAGACTATACTCTGGCACTGCGCGTTACCACACTCAGATGCTGCGGGTTCGAGAGTTTATCCGTTTCCATCAGATCCCCAACCCACTTCGGCAAAGACTAGAGGAGTATTTCCAGCATGCTTGGTCCTACACCAATGGCATTGACATGAATGCTGTGCTGAAGGGTTTTCCTGAGTGCTTACAGGCTGACATCTGTTTGCATCTGAATCGTACACTGCTGCAGAGCTGTAAAGCTTTCAAGGGTTCCTCCAAAGGCTGCTTGCGTGCTCTGGCTATGAAGTTTAAGACTACTCACGCTCCTCCAGGAGACACCTTGGTCCATGCTGGAGATGTGATTTCAGCGCTATACTTCATATCTCGGGGCTCCATCGAGATTTTAAAGGGAGATGTAGTTGTGGCTATTTTAGGCAAGAATGATATATTTGGAGAGCCCATTAACTCATATGCTCGTCCTGGAAAGTCAAGTGCAGATGTGAGAGCACTTACGTACTGTGACCTGCACAAAATCCACAGAGATGATGTCCTGGAGGTCTTGGAAATGTATCCAGAGTTCTCTGACTACTTTTGGAGCAATCTGGAAATCACTTTTAATTTGAGAGACACTAACACTAAAGCTGGGTCAATGAGCAGTGACCCTGATGATTCGGACAATGGCGGTCTGGACCATCACACACGCAGAGCAAAGTTGTTCTTTCAATCTAAAAGAAACTCCATCTCTCGAGATACAGAGAGAACAGAAGACAGGCTCAACAGGATGACTTTCAGAACACAGACTTCAGGAAAACAGCATGAGAACAGACAAACTGCTCATCGCAGCTCAGACATCTTTGCCTCACAGTCAAGCAGCGATGAAGAGGAAGAGACTCAACGACCCTCTGTGATGGTGGACTGCTCTCAGAGCCATATCAATAGCGTTAGCAATGCTAACAGGGACAAGGACCACAACAGCAGTAACTCGTTCAACGCACTCTCAGGAGCTTTTTCAGGGGTTTCTAACATCTTTAGCCTTTGGGGAGACAGCAGCCGTGGCCATCACTACCAGGAAGTACCCAGCCACAGCATGTCCTTCCCCTCATCTTCAGTTCCCTCTAACACCGTCCTGCACAATGTCACCTATGGGCAATGCTCAGAGGTAGAGAACAGACTGGAAATGATGCACAGGCAGCTCTACCGATTGGAGAAGCGCATGTCAAAGGACATTGGAGCCATAATGCAGTTGCTTCAGAGGCAAATGGTGCAGGTTCCACCAGCCTACAGCTCAGTGACGTCTCCTACAGAAGCATCGCCAATTCCACCCAAACCTGGACAGAAATTGGTTCAGCCTGTGAATCCTTTAGAAACAGAGACTCCATCTATCCTGTCTGAGGTATTTCTATATGTTTactaaaaatattcaaacaaaaattTAGGTCAGCTAATCAGTGGTGCagtacagtaggtagtgctgttgcctcacagcaagaaggtcgctggttcaagcctcggctgggtcagttggcgtttctgtgtggaatttgcatgttcttcctgtgttcacatggtgcacagtccaaagacatgcagtacaggtgaattgggtaggctaaattgtctgcagtgtaagagtgtaagtgagtgtgtgtggatgcttaatgcttttcatacttaaaacattactgcctacaactatgtgtacACCCATTCATTGTACATATGGCTGTCTACAttgccaattttacattgtcaaaCTGTTTTTtggggagtatgctgttgtatgttgttgtattttgcactgtctgtaatttgcactgtctggagccagcttttcactcatcataacacacatgctgctgatgatgtgacaataaaagtgatttgatttgatttgatttaatttaatttgaggtgatgtttcccagggatgggttgcagttggaagggcatccgctgcgtaaaacatatgctgtataagttggcggttgattccactgtagtgacccgagattaaaaaaaggactaagcc

Function

symbol description
kcnh2a Predicted to enable voltage-gated potassium channel activity. Predicted to be involved in potassium ion transmembrane transport and regulation of membrane potential. Predicted to act upstream of or within potassium ion transport; regulation of ion transmembrane transport; and transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including digestive system; gill; heart; immune system; and muscle. Human ortholog(s) of this gene implicated in long QT syndrome; long QT syndrome 2; and short QT syndrome. Orthologous to human KCNH2 (potassium voltage-gated channel subfamily H member 2).

GO:

id name namespace
GO:0071805 potassium ion transmembrane transport biological_process
GO:0042391 regulation of membrane potential biological_process
GO:0034765 regulation of ion transmembrane transport biological_process
GO:0055085 transmembrane transport biological_process
GO:0006811 ion transport biological_process
GO:0006813 potassium ion transport biological_process
GO:0005887 integral component of plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0005216 ion channel activity molecular_function
GO:0005244 voltage-gated ion channel activity molecular_function
GO:0005249 voltage-gated potassium channel activity molecular_function
GO:0005267 potassium channel activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-070912-699 Predicted to enable voltage-gated potassium channel activity. Predicted to be involved in potassium ion transmembrane transport and regulation of membrane potential. Predicted to act upstream of or within potassium ion transport; regulation of ion transmembrane transport; and transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including digestive system; gill; heart; immune system; and muscle. Human ortholog(s) of this gene implicated in long QT syndrome; long QT syndrome 2; and short QT syndrome. Orthologous to human KCNH2 (potassium voltage-gated channel subfamily H member 2).

Ensembl:

ensembl_id ENSDARG00000029881

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00030871 False 4532 mRNA 0.48 15 24080694 24168670
TCONS_00030872 True 3999 mRNA 0.49 14 24081050 24165596

Neighbor

gene id symbol gene type direction distance location
XLOC_015434 NA coding upstream 56246 24022798 ~ 24024448 (+)
XLOC_015433 CR788285.2 coding upstream 65751 24013250 ~ 24014943 (+)
XLOC_015432 NA coding upstream 140364 23936535 ~ 23940330 (+)
XLOC_015431 si:dkey-24c2.9 coding upstream 243271 23823622 ~ 23837423 (+)
XLOC_015430 gorasp1a coding upstream 260414 23808640 ~ 23820280 (+)
XLOC_015436 map4l coding downstream 8336 24177006 ~ 24252506 (+)
XLOC_015437 BX000358.1 coding downstream 92547 24261217 ~ 24261296 (+)
XLOC_015438 fitm1l coding downstream 136184 24304854 ~ 24308682 (+)
XLOC_015439 mrpl34 coding downstream 148795 24317465 ~ 24320183 (+)
XLOC_015440 CR384062.1 coding downstream 179919 24348589 ~ 24351040 (+)
XLOC_015428 NA non-coding upstream 301265 23772918 ~ 23779429 (+)
XLOC_015426 BX649335.1 non-coding upstream 400705 23679873 ~ 23679989 (+)
XLOC_015443 NA non-coding downstream 315603 24484273 ~ 24497841 (+)
XLOC_015446 NA non-coding downstream 434622 24603292 ~ 24612068 (+)
XLOC_015449 NA non-coding downstream 547644 24716314 ~ 24720787 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000004_07515025_07559926 KCNH2A, KCNH6, KCNH2 coding CI01000004 null 7515025 ~ 7560401 (+)