CI01000004_07515025_07559926 (KCNH2A, KCNH6, KCNH2)


Basic Information

Item Value
gene id CI01000004_07515025_07559926
gene name KCNH2A, KCNH6, KCNH2
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000004
NCBI id null
chromosome length 17451736
location 7515025 ~ 7560401 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000004_07515025_07559926.mRNA
ATGCCTGTTCGACGGGGACACGTTGCGCCTCAAAACACCTTTCTGGACACCATCATTCGCAAATTCGAGGGTCAGAATCGCAAATTCATCATCGCCAATGCTCGAGTTGAAAACTGTGCCATTATCTTCTGCAATGATGGCTTTTGCGGCATGTGCGGCTACACACGTGCAGAGGTCATGCAAAAGCCATGTACGTGCAGTTTTCTGTATGGACCGCATACTGGACGACCAGCGATGGCCCAGATGGCCAAAGCCTTACTAGGCTCTGAAGAACGGAAGGTGGAGATCTCCCTGTACAGAAAAGATGGTGTGTGTTTGCCGTGCCTTGTGGATGTGGTTCCAGTTAAGAATGAGGATGGTGTAGTCATCATGTTTATCCTGAACTTTGAGCTGGCAGATCAGCCGGACAGACCCATCGACAGCTCACCGGGCAGAGACATCAACCACAAACACACCATCCCCTGGCTCTCTAAAGCAAGAAGACACAGACTCAGGCTGCCTTTGCCCCTGTTGCGCTCCCTGAGTGGCAGTAAACAGTCTCTGCATGAAGATTCTGAAAAAGGCTACATGCAGCCGATGCCCCATATGGGCCATGAGTCTGTAGCCCTGGACAAACTGCTCTCCCTGCCTGAACGCTCCGCACTTGGGGGATCTCAGCTGTTGTTGTGGGAAGAGGCCTCTCCGTCCAGCTGCAGCATGGCCCACAGCCGCTCCTGTGAGAGCCTGTGTGGCATGCGGCCCTCACCCTCCACCAGTGACTTCAACTGGGACAGGAAGCTGCCCGTCAGACCCAGTAGCACAGGTGCCATGCACCGCAAAGCCAGCTTACAGAATGCTACTTCAGACTCGGATCTCATTCGGCTCCGGACCTCAGTCCGGGTTCCCCAAATATCACACAACTTAATAGATATGAAGCCGGACCCCCTAATTGCTGTTCCGCCCAGTGAGATTGACATCATCGCCCCCTGCAAACTAATAGACCGGACCCATAATGTGACAGAGAAGGTCACTCAGCATGTTTGTGCTTATCAGGGGAACAGAGGATATCCATCAAGCCCTGCAGCTGGGCTACTGAGAGCGAGGAGGTGGATCAGACAGCCAGCTGCAATTACATCTCTTCCCGAGTGGGACTTCCACAGAGAAGAGAGAGAGCGAGAGGAACAGGATGAACGTATTTGCTGTTTTTGTGAGCAGAAGGTGAGTGCCAGAGGCAGCATTCCTCAGGAGGGGGCGCAAGAGAGCAATGAGCGGAGAAACACTCGGGTGAAGAGGGCTGTTCGCATCTCTAGTATTGTTGCACAGGAGAGCCTCTTGTTGGCGGCGTGTAAGATTGGTGTTGTGGTGTCAGAACTGGGCCCTTCTCATCACAGTCACAGCAGTCAGGCATACCAGAGGAGTCATGGATTCTGCCACTTGAGCCGTGAGCAGTGGCAGTCGGAAGATTATTTGTGGATCATGATTCTGACCTTGGTGCTGAATCCTTTGAACAAGCTCTTCCAGTCCTGTCCTCCTTCTGTTCAGCTTCAGCCTTCATTTCAGATACACATGCCTTGCAAACAAGGCTCCCAGAGCCTCCACTTTTGGGATAAGCCAAGTCCCTCTCTTGGCCAAGAGAGCAGAGAGGTGCTGTCTCTGGGTGCAGATGTCCTTCCTGAGTATAAGTTGCAGGCTCCCCGTATCCACAAATGGACCATCTTGCACTACAGCCCCTTCAAGGCAGTCTGGGACTGGGTCATCTTGCTACTGGTCATCTATACAGCAATCTTCACACCTTATTCAGCTTCTTTCCTGCTCAGCGATGAGGAAGAGGCTGCCATGCAGCGCTGCGGTTACTCCTGCAGTCCGCTGAACGTGGTGGACCTCATTGTGGATATCATGTTCGTAGTGGACATTGTGATTAACTTTCGCACAACCTACGTAAACAGCAATGACGAAGTGGTCAGTCAGCCTGGCCGAATAGCCGTCCACTATTTTAAAGGCTGGTTCCTCATTGACATGGTGGCTGCCATTCCCTTTGACTTGCTCATTTATCGTTCAGGAGAAGAGACGACGACTCTGATTGGCCTACTGAAGACAGCTCGGCTGCTGCGATTAGTGCGTGTGGCACGTAAACTCGATCGCTACTCTGAGTATGGAGCTGCAGTGCTCTTTCTCCTCATGTGCACCTTTGCACTTATCGCCCACTGGCTGGCCTGCATCTGGTATGCTATTGGGAACGTGGAGAGGAGCAGTCAATCTCGCATTGGTTGGCTTGATTCTTTGGGTGATCAGCTGGGGAAGCCGTATAATGAAACGAGTCCTGGATCAGGACCCTCGATTAAAGATAAATATGTCACTGCCCTCTACTTCACCTTCAGCAGCCTCACCAGCGTGGGCTTTGGAAACGTCTCCCCAAACACCAATTCTGAGAAGATCTTTTCTATCTGTGTCATGCTTATTGGAGCACTGATGTATGCTAGCATATTTGGAAATGTGTCAGCCATCATCCAGAGGCTGTACTCTGGCACCGCACGTTACCACACTCAGATGCTACGGGTTCGGGAATTTATCCGTTTCCACCAGATCCCCAACCCACTCAGGCAAAAACTGGAAGAGTACTTTCAGCATGCTTGGTCCTACACTAACGGCATTGACATGAATGCTGTGCTGAAGGGGTTCCCAGAGTGCTTACAGGCAGACATCTGTTTGCATCTGAATCGAACATTGCTGCAGAACTGTAAAGCTTTCAAGGGTTCCACTAAAGGCTGCTTGCGTGCTTTGGCTATGAAGTTCAAGACCACACACGCCCCACCAGGAGACACCTTGGTCCATGCTGGCGATGTGATTTCAGCGCTGTACTTCATTTCTCGTGGCTCCATTGAGATCTTAAAGGGAGATGTGGTAGTGGCCATTTTAGGCAAGAATGATATATTCGGAGAGCCCATTAACTTATATGCGCGTCCTGGAAAGTCAAGTTCTGATGTGAGAGCACTGACGTACTGTGACCTGCACAAAATCCACAGAGAAGATGTACTGGAGGTCTTGGACATGTATCCAGAGTTCTCAGACTACTTCTGGAGCAACCTGGAGATCACCTTCAATTTGAGAGACACTAACACTAAAGCCGGGTCAATGAGCAGTGACCCTGATGATTCTGACCACGGCTGTCTTGATCATCACACGCGAAGAGCAAAGCTGTTCTTTCATTCCAAAAGAAACTCCATCCCACAAGTAGCAGATACAGAGTGGACAGAAGACAAACTCAATAGGATGACTCTCCAAACACAGAATTCAAGCAAACAGCACGAGGACAGACAAGCCACTCATCGAGAGCCGGACATCTTTGCTTCCCAGTCCAGCAGTGATGAAGAGGAAGAGACTCAACGGCCCACTACGATAATGGACTGCTCTCAGAGCCATATCACTAGTGTCAGCAATGCTAATAGAGACAAGAACCTCAACACCAGTAACTCTTTCAGTGCGCTGTCAGCTTTTGGGGGGACAGTCGTGGCCATCAGTACCAGGAAGTACCCAGCCACAGCATGTCTTTCCCCTCATCTTCGGTTCCCTCAAATACTATCCTGCAAAATGTCACCCATCGTCATTGCACTGAGATTGGAAAAGCGCATGTCAACAGACATTGGGGCCATAATGCAGTTGCTTCAGAGGCAGATGGTGCTGGTTCCACCAGCCTACAGCTCTGTGACGTCCCCTATAGAAGCATCTCCAAATCCACCAAAACCAGGCCAGAAACTGGTCCAGCCTGTTAACCCTTTAGAGACAGAAACGCCAGCCATTTTCTCTGAGATACTTGATCCCCACGACTTTGCTGGCAGTCCCATAAAATCCACTGAAAGTCTGTCTGGTGCAATGGAGCTCCAGCTCCTGGACTGTTCCTCACAGCCCTCCTCTTCTGGGGCTTATACAGGGAGGTGGCCACATAGCATGAGCCACAACGCAGGGAGCGTCCCTGGTGATTTTACAGCCCACACTGATCGCCAACAAATAGCCGATCAAGGTGGTTATCATTTAATAGATGCAGAGCCTATTGGAACTGTTCACCATCCACAGGCTGGACTGAGGAGGAAGAACCCCAAGCTCATCTCGAGTAGCCCAAATACCTCAGAGTGAGTGAATCCAGGGAACAATGGTGAATCCTGCTGAATAACATGCCAGTAATTTACATGAAAGCATGTGTTTATTTTTTTCAAGCCATCCACTGCACAGATTTTCCCATGACAATATTTTATCACTCTAAATATATAATCATCAGTTTGGCCAAAGGGTCAAAATGTGATTTAGACAGATTATGATTGAAAATCCATTTTGAATACAATCCATATCACTATTAGTGTTGAAATATACATATATAATCAGCTGCCACTGGTTCAAGCCAAACACATCCAGTAGTAAGCCATATATAAATGTGCTAGAAAGACATTTATAGGGAATGCGGTATTAGACAGAGTATAGCTTGGAATGTTCAAATGTAATATAACATGTAATTTATTGCAATCTTGAGTAGGAATATTTATTGTTAGCTTACTATAAATTGATTATTGTGCACATTTTATCTCCTATGAACTTGTAATCACATTCACACTGA

Function

symbol description
kcnh2a Predicted to enable voltage-gated potassium channel activity. Predicted to be involved in potassium ion transmembrane transport and regulation of membrane potential. Predicted to act upstream of or within potassium ion transport; regulation of ion transmembrane transport; and transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including digestive system; gill; heart; immune system; and muscle. Human ortholog(s) of this gene implicated in long QT syndrome; long QT syndrome 2; and short QT syndrome. Orthologous to human KCNH2 (potassium voltage-gated channel subfamily H member 2).
kcnh6 Predicted to enable voltage-gated potassium channel activity. Predicted to be involved in potassium ion transmembrane transport; regulation of heart rate by cardiac conduction; and regulation of membrane potential. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane.
kcnh2 Enables several functions, including C3HC4-type RING finger domain binding activity; protein homodimerization activity; and voltage-gated potassium channel activity. Involved in several processes, including ion transmembrane transport; potassium ion homeostasis; and regulation of ion transmembrane transport. Acts upstream of or within regulation of heart rate by cardiac conduction. Located in cell surface; perinuclear region of cytoplasm; and plasma membrane. Part of inward rectifier potassium channel complex. Implicated in long QT syndrome; long QT syndrome 2; and short QT syndrome.

NR:

description
potassium voltage-gated channel zerg2

GO:

id name namespace
GO:0042391 regulation of membrane potential biological_process

KEGG:

id description
K04909 KCNH6, KV11.2; potassium voltage-gated channel Eag-related subfamily H member 6

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000004_07515025_07559926.mRNA True 4585 mRNA 0.49 22 7515025 7560401

Neighbor

gene id symbol gene type direction distance location
CI01000004_07375432_07378296 NA coding upstream 136338 7375432 ~ 7378687 (+)
CI01000004_07366683_07372144 GORASP1, GORASP1A coding upstream 142587 7366683 ~ 7372438 (+)
CI01000004_07360794_07364249 CSRNP1A coding upstream 150426 7359772 ~ 7364599 (+)
CI01000004_07322380_07326368 NA coding upstream 188477 7322266 ~ 7326548 (+)
CI01000004_07319769_07320274 NA coding upstream 194314 7319156 ~ 7320711 (+)
CI01000004_07568950_07581744 NA coding downstream 8549 7568950 ~ 7582672 (+)
CI01000004_07585030_07601316 NA coding downstream 24326 7584727 ~ 7602713 (+)
CI01000004_07642418_07645369 FITM1 coding downstream 81960 7642361 ~ 7647147 (+)
CI01000004_07654234_07655677 MRPL34 coding downstream 93833 7654234 ~ 7656383 (+)
CI01000004_07686845_07692184 NR2F6, NR2F6A, NR2F6B coding downstream 125617 7686018 ~ 7693082 (+)
G28714 NA non-coding upstream 18161 7491896 ~ 7496864 (+)
G28686 NA non-coding upstream 77289 7437236 ~ 7437736 (+)
G28682 NA non-coding upstream 86263 7427242 ~ 7428762 (+)
G28379 NA non-coding upstream 127184 7387581 ~ 7387841 (+)
G28372 NA non-coding upstream 127626 7385044 ~ 7387399 (+)
G28710 NA non-coding downstream 59714 7620115 ~ 7633578 (+)
G28730 NA non-coding downstream 101506 7661907 ~ 7663273 (+)
G28731 NA non-coding downstream 104324 7664725 ~ 7664993 (+)
G28732 NA non-coding downstream 105671 7666072 ~ 7666828 (+)
CI01000004_06571261_06572539 SEP15 other upstream 940604 6570771 ~ 6572667 (+)
G28302 NA other upstream 1012938 6470028 ~ 6502087 (+)
G28165 NA other upstream 1782024 5732589 ~ 5733001 (+)
G27805 NA other upstream 2141222 5372825 ~ 5373803 (+)
CI01000004_03550525_03552621 PTGER4C other upstream 3962579 3550329 ~ 3553423 (+)
CI01000004_08414451_08436256 NA other downstream 873304 8414316 ~ 8439933 (+)
G28859 NA other downstream 1038834 8599235 ~ 8599603 (+)
CI01000004_08976512_08980033 TTPA other downstream 1416037 8976254 ~ 8980984 (+)
G30797 NA other downstream 2936975 10497376 ~ 10497788 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_015435 kcnh2a coding NC_007113.7 CM002886.2 24080694 ~ 24168670 (+)