XLOC_016348 (prrx1a)


Basic Information

Item Value
gene id XLOC_016348
gene name prrx1a
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007113.7
NCBI id CM002886.2
chromosome length 59640629
location 23165250 ~ 23172708 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00032202
CAGTGTGCGCCGTTTGAAGTACCGGAGAAAGAAGCTGAGAGAAGCTCGTCCGGCCTCCTACCATTGGGCGTAAATCCTTCATCTGTGCCATCAAACCTTCCTCGCCAGTTTACTCATTCCCTCACTCTGGGAATGAGAGGGGAAAGTCTCTGCTGCAGAGTTAAGAGTGGAGTCATCGGCAAAACTTTGGAAACTTTGGAGCTCTTGAACTGGAGATGTTTGTTCTGTGATGCAGTTTCCCATGAAGACGCGCGATTGTCAAATAAAAGAGAGCTAGCAAATACGCCTTTTTTGGATTCACAAGACGCCGATCTACGGATGTAAAAACAGAAATCGATAAATTTGTCGAGTATAGAGTGGTTGTTTATGGTCGAAACGTAACCCATGTTGGTTGTAGGTAGAGGATATCTTGGGTTTCGTCAATTTGCGTCATGACTTCCAGCTATGCTCATGTAATGGACAGACAAGCCACACTACCAAACCGACTGGAGACTGCGATCACCGCGAATCAGGATCATTTACAGGCTAAAAAGAACTTCTCCGTGAGCCACCTGTTGGATCTGGAGGAGGCGCGGGAGATGGTGGGAGCTCAAGCGGAGGAAAGCGCAGGGGAGGCGGGCAGGAGTATGCTGGAGTCTCCGGGACTCACCAGCGGGAGCGACACTACACAGCAGGAGAACGAGCAGCTCAACGCAGAGGAGAAGAAGAAGCGTAAACAGAGGCGAAACAGAACCACGTTCAACAGCAGTCAGCTGCAGGCCTTAGAGAGAGTGTTTGAGAGGACGCATTACCCCGATGCTTTCGTCAGGGAGGACTTGGCACGACGGGTCAACCTCACTGAAGCACGAGTTCAGGTATGGTTTCAAAATCGACGGGCTAAGTTTCGACGAAATGAACGTGCGATGCTGGCAAGTAAAAATGCTTCATTGCTCAAGTCTTTCTCAGGAGAAGTAACAGCCGTAGAGCAGCCCATTGTCCCACGACCCGCACCCAGACCCAATGACTACCTGTCCTGGGGAAGCTCACCGTCATACAGTGCCATGGCAACTTATTCTCCCTCGTGCGCCAACAACACAACAGCCCAGGGCATGAATATGGCCAACAGTATCGCCAACCTGAGACTGAAAGCCAAAGAATACAGCCTGAACCAGGTACCCACTGTCAACTGAAGCGGGCAGCTGGGCTGTCAAAGACTCTCAGAACAATCCCAATGTCCCAGCCCCAAATCTATTGACATAAACAACGTTTTCTGTCCTCCTCTATGTGTTTTACTCTTATCCATCAAAGAACAGAAGCAAACGAGAACAGCTCCAAGGCACCAAGCTTTCCTAAAACCAATGATTTACATTGAACCGTCATGTTCCTGGTATGTGGGGAAATGACATGTGGGAAAATTGAGTTTTGGACAGCACAAAATGGAAAGTTTTCCCTGTTCACACTCACTGTGGCAGCGTAAGCGTGGTCAACCCTTTTGGAGATCGTGGCTTACTATAGATTTCTTTCTTGAGACTCCTGCCGACCACAGGGATTTGATGACCTCTGCGGAATCCATATACTACAATCTTGCGGACATCTGGGGAGTTTTTAGGATTTCCCCTTGATTTCTCATTGGAACTCGTAAATGCGCACTGAGGCCACAAATTGGGATTTGGATATTTTGGTTATTTGGGAACAGAGTGAAATTTGGCTTTCCTGTTACTGGACTCTAAAATCACTCTTCACTGTTGTCCGTTTAAAAAACATGCAAGGGGGTATCGGTTCATTTTGGCATATACAGAACTCTGGCCATGTATGTAAGTGATGAATTCAGAGCTTTGTTGATTATACCCcattatattttctaaatatatgcataaatatgtaaCATTACTTTGCAATAAAGATGTCCTAGCAATGTAATGTCATCAA

Function

symbol description
prrx1a Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including atrial cardiac muscle cell action potential; epithelial to mesenchymal transition; and heart looping. Predicted to be active in nucleus. Is expressed in several structures, including cranial vault; fin; gill; mesenchyme; and mesoderm. Human ortholog(s) of this gene implicated in agnathia-otocephaly complex. Orthologous to human PRRX1 (paired related homeobox 1).

GO:

id name namespace
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0007275 multicellular organism development biological_process
GO:0001837 epithelial to mesenchymal transition biological_process
GO:1904888 cranial skeletal system development biological_process
GO:0086014 atrial cardiac muscle cell action potential biological_process
GO:0001947 heart looping biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0003677 DNA binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-020905-5 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including atrial cardiac muscle cell action potential; epithelial to mesenchymal transition; and heart looping. Predicted to be active in nucleus. Is expressed in several structures, including cranial vault; fin; gill; mesenchyme; and mesoderm. Human ortholog(s) of this gene implicated in agnathia-otocephaly complex. Orthologous to human PRRX1 (paired related homeobox 1).

Ensembl:

ensembl_id ENSDARG00000033971

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00032202 True 1908 mRNA 0.47 4 23165250 23172708

Neighbor

gene id symbol gene type direction distance location
XLOC_016347 BX548024.1 coding downstream 77926 23084639 ~ 23087324 (-)
XLOC_016346 NA coding downstream 138188 23025245 ~ 23027062 (-)
XLOC_016345 mllt1b coding downstream 160895 22970140 ~ 23004355 (-)
XLOC_016344 sap130b coding downstream 199123 22931159 ~ 22966127 (-)
XLOC_016342 myo7bb coding downstream 237292 22880605 ~ 22927958 (-)
XLOC_016349 niban1b coding upstream 122707 23295415 ~ 23349116 (-)
XLOC_016350 ivns1abpb coding upstream 206693 23379401 ~ 23391266 (-)
XLOC_016351 NA coding upstream 233764 23406472 ~ 23443189 (-)
XLOC_016352 si:ch73-129a22.11 coding upstream 234076 23406784 ~ 23411368 (-)
XLOC_016353 si:ch211-14p21.3 coding upstream 303015 23475723 ~ 23479714 (-)
XLOC_016343 BX649390.1 non-coding downstream 267849 22897285 ~ 22897401 (-)
XLOC_016341 NA non-coding downstream 296530 22857105 ~ 22868720 (-)
XLOC_016340 NA non-coding downstream 313545 22845662 ~ 22851705 (-)
XLOC_016369 NA non-coding upstream 853861 24026569 ~ 24069434 (-)
XLOC_016370 CR788285.1 non-coding upstream 903305 24076013 ~ 24105475 (-)
XLOC_016372 dre-mir-736 non-coding upstream 1088509 24261217 ~ 24261296 (-)
XLOC_016374 NA non-coding upstream 1137927 24310635 ~ 24317436 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000004_06156517_06161977 PRRX1A, PRRX1, NOTO, PRRX1B coding CI01000004 null 6156329 ~ 6162069 (+)