XLOC_017595 (parp1)


Basic Information

Item Value
gene id XLOC_017595
gene name parp1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007131.7
NCBI id CM002904.2
chromosome length 55201332
location 43648369 ~ 43689779 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00034922
ATTCCTCATTGCGCTGTAACGTGAGTTGTCGGCCTGTCTGACTAGAATTAGTCTGCAAACTTCTCCTTTTAACAGAAATATCTGCAGAGATGGCCGACTCACAGGACGACAAGCTGTACAAAGCCGAATATGCAAAAAGCGGACGCGCCTCATGCAAGAAATGCAAAGACAACATTGCTAAGGACTCGCTGAGGATGGCCATCATGGTGCAGTCTCCCATGTTTGATGGCAAAGTCCCTCACTGGCACCATTTTTCTTGCTTTTGGCTCCGGGCCGCAGTTCAGTCTCCTTCTGATATATCTGGATTTACTGACCTCCGCTGGGATGACCAAGAGAAAGTGAAGACAGCCATTGAGAGTGGAGGTGCTACAGGAGGGAAAGGAGGACAGAAGGGAGCGGCTAAAGGAGAGAAGACGCTGAATGACTTTGCAGTGGAGTATGCTAAATCCAACAGAAGCACCTGCAAGGGCTGCGATCAGAAAATTGAAAAGATCCGTGTGTCGAAGAAGACTGTGGACCCAGAGAAACCTCAGCTTGGTCTAATCGATCGCTGGTACCACACCGGCTGCTTTGTGAGTCGTCGGGAGGAACTGATATTTAAACCAGAGTACAGCGCTGCCCAGCTCAAAGGATTCGCAGTTCTACGAGATGAAGACAAAGAGGAGCTGAAGAAACGGCTTCCTGCTGTGAAGAGCGAAGGAAAGAGAAAAGCTGATGAAGTAGATGGAGGAGTCTCtaaaaaacagaagaaagaagatgAAAAACTAGAGCAGAATCTGAAGGATCAAAGCCAGCTGATCTGGGGAATTAAGGACAAGCTGAAGAAGTTCTGCTCCATCAATGACATGAAGGAACTGCTAATTGCTAACAGTCAGGAAGTTCCTTCTGGGGAGTCAAATATTGTGGATCGACTATCAGACTGCATGGCATTTGGGTCCCTGAAGCCTTGTGAGACTTGCAAAGGGCAGCTTGTGTTTAAAAGTGATGCGTATTACTGTACTGGAGACATCTCTGCGTGGACTAAATGTGTATTCAAGACTCAGACGCCTGATCGCAAAGACTGGGTCACCCCTAAGGAGTTCAGTGAGATCCCGTTCCTGAAGAAGTTTAAGTTCAAGCGACAGGACCGTGTGTTTCCTAAAGACGCTCCTCCCGCTGCTGCCACTCCATCATCTGGTTCTACCACTTCAGCTGCCACAAGTGTGTCCAGCGCCAGTAAAAACCTCACTGAGGCACCTGCAGATAAGCCTCTGACTGGAATGAAGCTCCTGGCTGTGGGAAAGCTCAGTAAGAACAAAGATGATCTGAAGAAATTTGTGGAAGATCTGGGAGGAAAAATCACAGGCACGGCCAGCAAAGCTGCTCTCTGCATCAGCAGCAAGAAGGAGATTGAGAAGATGAGTAAGAAAATGGAGGAGGTGAGAGACGCAGGTGTCCGCGTGGTGGCTGATGATTTCCTTACTGACATCAAGGAGTCCGGCAAGGCCCTTCAGGAGCTCATCTCTCTGCATGCCATTTCCCCCTGGGGCGCTGAAGTTAAAGTCGAGGCCCCGGCTGCAGCCGCGGCCACCAAATCCACCGGAGCTCATTCCTCAAAGAGCACCGGCAAAGTCAAAGAGGAGGAAGGTGGAAGCAAATCAAAGAAAATGAAGCTGACAGTGAAAGGAGGAGCTGCAGTAGATCCAGATTCAGGTCTGGAAAACTGTGCTCATGTTCTGGAACAGAATGGAAAGATTTACAGCGCCACACTGGGTCTCGTGGACATCGTCAGAGGGACAAACTCATACTACAAACTACAGCTGCTGGAGGATGACGTTCAAAAGCGgtaCTGGGTGTTTAGATCGTGGGGTCGAGTCGGGACCACCATTGGAGGAAACAAATTGGACAAGTTTTACGATAAGAACTCTGCTATGGACAATTTCTGTGGTGTGTATGAGGAAAAGACAGGGAATGCTTGGGCCTCCAGCAACTTCACAAAGTACCCCAATAAGTTTTACCCTCTGGAGATTGACTACGGACAGGATGAGGAGGCTGTGAAGAAGTTGACTCAAAGTGCAGGTGCCAAATCTCAGCTGGAAAAACCTGTGCAAGACCTCATCCGAATGATCTTCGATGTGGAGAGCATGAAGAAAGCCATGGTGGAGTTTGAGATTGACTTGCAGAAGATGCCTTTGGGAAAACTAAGCAAGCGACAGATCCAGAGTGCTTATTCCCTTCTAAGCGAAGTTCAGCAGGCTGTGGCAGATAGCTCCTCAGAATCACTGATCCTAGATCTGTCTAATCGCTTCTACACACTGATACCGCACGACTTCGGCATGAAGAAACCACCACTATTGAGTAATGTGGATTACATCCAGCAAAAGGTGCAGATGCTGGACAACCTTTTGGACATCGAGGTGGCCTACAGCCTGCTTCGGGGAGGAGTGGAGAACAACGAAAAAGATCCCATTGACATCAACTATGAGAAACTCAAAACCAAAATTGAGGTCGTCGACAAGTCTTCACATGAGGCTCAGCTTATCCTTCAATATGTGAAGAACACACATGCTGCTACTCACAACACCTACACACTGGATGTTGAGGAGATCTTTAAGATTGAGAGGGAGGGCGAGTATCAGCGTTATCGCCCCTTCAAAGAGTTACCCAACCGCCAGCTGCTGTGGCACGGCTCGCGCACCACCAACTATGCTGGTATTCTGTCTCAGGGTCTCCGCATCGCTCCTCCGGAGGCCCCAGtgACGGGTTACATGTTTGGCAAAGGTGTTTACTTTGCTGATATGGTGTCGAAGAGTGCCAACTACTGCCACACGTCTCAGGCTGATCCTGTGGGCCTCATTCTGTTAGGAGAGGTTGCATTAGGGAACATGCATGAACTGAAGAAAGCCTCACACATTACAAAGCTACCAAAGGGTAAACACAGTGTAAAAGGTTTGGGAAGAAGTGCTCCAGACCCAAGAGCTACAGTATCTCTCAATGGAGTGGACATTCCTCTGGGCAAAGGCATGAACACAAATATTGATGACACAAGTCTGCTCTACAACGAGTACATCGTTTATGATGTTTCTCAGGTTAACCTGAAATACCTGCTGAAGATCCGCTTCAACTATCAGACGTCTCTGTGGTGAGACGCCGGTTAGATCTGGAGAGGTTTTTGGATGCCACTGAATCCCCCTGTTACAGCTTTAGCATCAAGAACCAAACAGCACATGGGTTTAGAAATGATTAAATCCGTTCTCTTGCGCTTTGGCAGCACATTCCCCATTGCTCTAGTCTGTTAGTTTGGAGTACTTTAAGTGGTTCTACCCAAATCACAAACTGCATTGTTGCAAATGTGGCCACCTTTCTACAAGCAACATGATTGGACTTCTCTGTGAAATGTTTCTTTATAAGCTACCAACAGTGGATAGGTAGACTGTCTTCCATATGTTTCATAggccttttctttcttttaatagtTTTGCTAAACCTGGATTCAGGTTACTTGTAACACATGTAGTGTTTACGGTTTTGTTCGGCCTCTcgatttaaaacaaataagaatgtACAGTTTTAGGAAAAAAATGTTGTAAGCTAGGATATAGCCTGCTGCAAGCGAGTAATCTTTTACTAGAATTGCCAATGTATGAACAAGTATTTTGTATGTTAAACATGTACCAACCTAGTTTTGCTTTTTTGAGTTTACTGTCCCTTATTGAAACGTACTTGGGCCATTTGAAATGGCTATCAAAATCTAAGCTGCTGTACTCACGCACCTGTAataagttttgttgttgtttttggcaAACATTTCTCCACAGTATTTGTGGACAAAATAAGTTTCCCAAAAAATGTCTTTGCATCAAAAATAAAACGGTTTTTGGCTT
>TCONS_00034923
TAACAGAAATATCTGCAGAGATGGCCGACTCACAGGACGACAAGCTGTACAAAGCCGAATATGCAAAAAGCGGACGCGCCTCATGCAAGAAATGCAAAGACAACATTGCTAAGGACTCGCTGAGGATGGCCATCATGGTGCAGTCTCCCATGTTTGATGGCAAAGTCCCTCACTGGCACCATTTTTCTTGCTTTTGGCTCCGGGCCGCAGTTCAGTCTCCTTCTGATATATCTGGATTTACTGACCTCCGCTGGGATGACCAAGAGAAAGTGAAGACAGCCATTGAGAGTGGAGGTGCTACAGGAGGGAAAGGAGGACAGAAGGGAGCGGCTAAAGGAGAGAAGACGCTGAATGACTTTGCAGTGGAGTATGCTAAATCCAACAGAAGCACCTGCAAGGGCTGCGATCAGAAAATTGAAAAGGACCAGATCCGTGTGTCGAAGAAGACTGTGGACCCAGAGAAACCTCAGCTTGGTCTAATCGATCGCTGGTACCACACCGGCTGCTTTGTGAGTCGTCGGGAGGAACTGATATTTAAACCAGAGTACAGCGCTGCCCAGCTCAAAGGATTCGCAGTTCTACGAGATGAAGACAAAGAGGAGCTGAAGAAACGGCTTCCTGCTGTGAAGAGCGAAGGAAAGAGAAAAGCTGATGAAGTAGATGGAGGAGTCTCtaaaaaacagaagaaagaagatgAAAAACTAGAGCAGAATCTGAAGGATCAAAGCCAGCTGATCTGGGGAATTAAGGACAAGCTGAAGAAGTTCTGCTCCATCAATGACATGAAGGAACTGCTAATTGCTAACAGTCAGGAAGTTCCTTCTGGGGAGTCAAATATTGTGGATCGACTATCAGACTGCATGGCATTTGGGTCCCTGAAGCCTTGTGAGACTTGCAAAGGGCAGCTTGTGTTTAAAAGTGATGCGTATTACTGTACTGGAGACATCTCTGCGTGGACTAAATGTGTATTCAAGACTCAGACGCCTGATCGCAAAGACTGGGTCACCCCTAAGGAGTTCAGTGAGATCCCGTTCCTGAAGAAGTTTAAGTTCAAGCGACAGGACCGTGTGTTTCCTAAAGACGCTCCTCCCGCTGCTGCCACTCCATCATCTGGTTCTACCACTTCAGCTGCCACAAGTGTGTCCAGCGCCAGTAAAAACCTCACTGAGGCACCTGCAGATAAGCCTCTGACTGGAATGAAGCTCCTGGCTGTGGGAAAGCTCAGTAAGAACAAAGATGATCTGAAGAAATTTGTGGAAGATCTGGGAGGAAAAATCACAGGCACGGCCAGCAAAGCTGCTCTCTGCATCAGCAGCAAGAAGGAGATTGAGAAGATGAGTAAGAAAATGGAGGAGGTGAGAGACGCAGGTGTCCGCGTGGTGGCTGATGATTTCCTTACTGACATCAAGGAGTCCGGCAAGGCCCTTCAGGAGCTCATCTCTCTGCATGCCATTTCCCCCTGGGGCGCTGAAGTTAAAGTCGAGGCCCCGGCTGCAGCCGCGGCCACCAAATCCACCGGAGCTCATTCCTCAAAGAGCACCGGCAAAGTCAAAGAGGAGGAAGGTGGAAGCAAATCAAAGAAAATGAAGCTGACAGTGAAAGGAGGAGCTGCAGTAGATCCAGATTCAGGTCTGGAAAACTGTGCTCATGTTCTGGAACAGAATGGAAAGATTTACAGCGCCACACTGGGTCTCGTGGACATCGTCAGAGGGACAAACTCATACTACAAACTACAGCTGCTGGAGGATGACGTTCAAAAGCGgtaCTGGGTGTTTAGATCGTGGGGTCGAGTCGGGACCACCATTGGAGGAAACAAATTGGACAAGTTTTACGATAAGAACTCTGCTATGGACAATTTCTGTGGTGTGTATGAGGAAAAGACAGGGAATGCTTGGGCCTCCAGCAACTTCACAAAGTACCCCAATAAGTTTTACCCTCTGGAGATTGACTACGGACAGGATGAGGAGGCTGTGAAGAAGTTGACTCAAAGTGCAGGTGCCAAATCTCAGCTGGAAAAACCTGTGCAAGACCTCATCCGAATGATCTTCGATGTGGAGAGCATGAAGAAAGCCATGGTGGAGTTTGAGATTGACTTGCAGAAGATGCCTTTGGGAAAACTAAGCAAGCGACAGATCCAGAGTGCTTATTCCCTTCTAAGCGAAGTTCAGCAGGCTGTGGCAGATAGCTCCTCAGAATCACTGATCCTAGATCTGTCTAATCGCTTCTACACACTGATACCGCACGACTTCGGCATGAAGAAACCACCACTATTGAGTAATGTGGATTACATCCAGCAAAAGGTGCAGATGCTGGACAACCTTTTGGACATCGAGGTGGCCTACAGCCTGCTTCGGGGAGGAGTGGAGAACAACGAAAAAGATCCCATTGACATCAACTATGAGAAACTCAAAACCAAAATTGAGGTCGTCGACAAGTCTTCACATGAGGCTCAGCTTATCCTTCAATATGTGAAGAACACACATGCTGCTACTCACAACACCTACACACTGGATGTTGAGGAGATCTTTAAGATTGAGAGGGAGGGCGAGTATCAGCGTTATCGCCCCTTCAAAGAGTTACCCAACCGCCAGCTGCTGTGGCACGGCTCGCGCACCACCAACTATGCTGGTATTCTGTCTCAGGGTCTCCGCATCGCTCCTCCGGAGGCCCCAGtgACGGGTTACATGTTTGGCAAAGGTGTTTACTTTGCTGATATGGTGTCGAAGAGTGCCAACTACTGCCACACGTCTCAGGCTGATCCTGTGGGCCTCATTCTGTTAGGAGAGGTTGCATTAGGGAACATGCATGAACTGAAGAAAGCCTCACACATTACAAAGCTACCAAAGGGTAAACACAGTGTAAAAGGTTTGGGAAGAAGTGCTCCAGACCCAAGAGCTACAGTATCTCTCAATGGAGTGGACATTCCTCTGGGCAAAGGCATGAACACAAATATTGATGACACAAGTCTGCTCTACAACGAGTACATCGTTTATGATGTTTCTCAGGTTAACCTGAAATACCTGCTGAAGATCCGCTTCAACTATCAGACGTCTCTGTGGTGAGACGCCGGTTAGATCTGGAGAGGTTTTTGGATGCCACTGAATCCCCCTGTTACAGCTTTAGCATCAAGAACCAAACAGCACATGGGTTTAGAAATGATTAAATCCGTTCTCTTGCGCTTTGGCAGCACATTCCCCATTGCTCTAGTCTGTTAGTTTGGAGTACTTTAAGTGGTTCTACCCAAATCACAAACTGCATTGTTGCAAATGTGGCCACCTTTCTACAAGCAACATGATTGGACTTCTCTGTGAAATGTTTCTTTATAAGCTACCAACAGTGGATAGGTAGACTGTCTTCCATATGTTTCATAggccttttctttcttttaatagtTTTGCTAAACCTGGATTCAGGTTACTTGTAACACATGTAGTGTTTACGGTTTTGTTCGGCCTCTcgatttaaaacaaataagaatgtACAGTTTTAGGAAAAAAATGTTGTAAGCTAGGATATAGCCTGCTGCAAGCGAGTAATCTTTTACTAGAATTGCCAATGTATGAACAAGTATTTTGTATGTTAAACATGTACCAACCTAGTTTTGCTTTTTTGAGTTTACTGTCCCTTATTGAAACGTACTTGGGCCATTTGAAATGGCTATCAAAATCTAAGCTGCTGTACTCACGCACCTGTAataagttttgttgttgtttttggcaAACATTTCTCCACAGTATTTGTGGACAAAATAAGTTTCCCAAAAAATGTCTTTGCATCAAAAATAAAACGGTTTTTGGCTTAT

Function

symbol description
parp1 Predicted to enable NAD+ ADP-ribosyltransferase activity and protein ADP-ribosylase activity. Predicted to be involved in double-strand break repair and protein poly-ADP-ribosylation. Predicted to act upstream of or within protein ADP-ribosylation. Predicted to be located in chromosome and nucleus. Predicted to be active in nucleolus. Human ortholog(s) of this gene implicated in several diseases, including arthritis; bacterial meningitis; neurodegenerative disease (multiple); stomach carcinoma; and type 2 diabetes mellitus. Orthologous to human PARP1 (poly(ADP-ribose) polymerase 1).

GO:

id name namespace
GO:0006302 double-strand break repair biological_process
GO:0006471 protein ADP-ribosylation biological_process
GO:0070212 protein poly-ADP-ribosylation biological_process
GO:0005634 nucleus cellular_component
GO:0005694 chromosome cellular_component
GO:0005730 nucleolus cellular_component
GO:0016740 transferase activity molecular_function
GO:1990404 protein ADP-ribosylase activity molecular_function
GO:0016757 transferase activity, transferring glycosyl groups molecular_function
GO:0046872 metal ion binding molecular_function
GO:0003950 NAD+ ADP-ribosyltransferase activity molecular_function
GO:0003677 DNA binding molecular_function
GO:0008270 zinc ion binding molecular_function
GO:0051287 NAD binding molecular_function

KEGG:

id description
ko03410 Base excision repair
ko04064 NF-kappa B signaling pathway
ko04210 Apoptosis
ko04214 Apoptosis - fly
ko04217 Necroptosis
ko04212 Longevity regulating pathway - worm
ko05415 Diabetic cardiomyopathy
ko03032 DNA replication proteins
ko03036 Chromosome and associated proteins
ko03400 DNA repair and recombination proteins

ZFIN:

id description
ZDB-GENE-030131-3955 Predicted to enable NAD+ ADP-ribosyltransferase activity and protein ADP-ribosylase activity. Predicted to be involved in double-strand break repair and protein poly-ADP-ribosylation. Predicted to act upstream of or within protein ADP-ribosylation. Predicted to be located in chromosome and nucleus. Predicted to be active in nucleolus. Human ortholog(s) of this gene implicated in several diseases, including arthritis; bacterial meningitis; neurodegenerative disease (multiple); stomach carcinoma; and type 2 diabetes mellitus. Orthologous to human PARP1 (poly(ADP-ribose) polymerase 1).

Ensembl:

ensembl_id ENSDARG00000019529

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00034922 False 3863 mRNA 0.46 23 43648369 43689777
TCONS_00034923 True 3802 mRNA 0.46 23 43648438 43689779

Neighbor

gene id symbol gene type direction distance location
XLOC_017594 si:dkey-206f10.1 coding upstream 3838 43602810 ~ 43644531 (+)
XLOC_017593 NA coding upstream 58588 43588656 ~ 43589781 (+)
XLOC_017592 NA coding upstream 92853 43548991 ~ 43555516 (+)
XLOC_017591 NA coding upstream 180387 43439137 ~ 43467982 (+)
XLOC_017590 NA coding upstream 213772 43431737 ~ 43434597 (+)
XLOC_017596 lin9 coding downstream 1429 43691208 ~ 43715242 (+)
XLOC_017597 clic5b coding downstream 235487 43925266 ~ 43968859 (+)
XLOC_017598 NA coding downstream 284754 43974533 ~ 43995913 (+)
XLOC_017599 BX510352.1 coding downstream 392753 44082532 ~ 44109219 (+)
XLOC_017600 LO018405.2 coding downstream 449966 44139745 ~ 44139861 (+)
XLOC_017589 AL928920.4 non-coding upstream 219046 43424002 ~ 43429323 (+)
XLOC_017601 LO018405.1 non-coding downstream 508919 44198698 ~ 44198815 (+)
XLOC_017605 CR545466.1 non-coding downstream 826384 44516163 ~ 44537787 (+)
XLOC_017606 NA non-coding downstream 874153 44563932 ~ 44567256 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
bowfin (Amia calva) AMCG00003652 parp1,xdh,LOC102777090,LOC107603072,LOC104966294 misc CM030121.1 CM030121.1 13071796 ~ 13116660 (-)