XLOC_022899 (gars1)


Basic Information

Item Value
gene id XLOC_022899
gene name gars1
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007135.7
NCBI id CM002908.2
chromosome length 42172926
location 20536056 ~ 20554969 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00045528
ATTCAGTTCCGCTCTGCGGTCGGTCGCTCCTCCTCCTCTCGGTCCATGCTGTCTGTGTGTAGCGCAACATCAGCACTGCTCCTCAGGACCGGTATATTTATCGTCCGCGCGGTTCCGAGGGTCAGAACCAGTCCCGTTCATCTGTGCGGCTCCTCACCCACCAGAGTGCTCTCCCTGTCGGCCCATTTGTgcaagaagaagaagagaagCGCGTGGCTGGAGATGACGGAAGGACAAAATATGGATGGCAGCATTGAGGAGATTTTGGCTCCATTGAGGCTGGCAGTAAAGGAGCAGGGTGATCTTGTGCGTCAGTTGAAAGCAGAAAATGCTCCTGATGTAGATGTCAGTAAGGCAGTAGCAGAACTCAAAGCTCGCAAGAGATTCCTTGAGGCCAAGGAGCTTTCCTTACAGCCCAAAGATGACATTGTTGACCGAACCAAGATGGAAGACACCCTAAAAAGACGTTTCTTTTACGATCAAGCCTTTGCAATCTATGGCGGTGTCAGTGGGCTGTATGACTTTGGGCCGGTGGGATGTGCTCTGAAGAACAATATTCTGCAGGTCTGGAGGCAACACTTCATCCAGGAGGAGCAGATTCTGGAGATCGACTGCACCATGCTTACACCCGAACCCGTTCTCAAgacatccGGGCATGTGGATAAGTTTGCAGACTACATGGTCAAGGATGTCAAGAACGGAGAGTGTTTTCGTGCAGACCACCTTCTTAAAGCTCATCTACAGAAATTAATGAGTGACAAAAAATGTCCGGCAGAAAAGAAAGCAGAGATGGACAATGTCATCACTCAGATGGATAACTACACTCAGCAGGAGTTGGCCGATTTGTTTGTGCAATACAACGTCAAGTCTCCCAGCACAGGAAATGATCTCACACCTCCAATTTCATTCAACCTAATGTTCCAGACCTCCATTGGGCCTGGAGGCAACATGCAAGGCTATTTAAGGCCAGAAACCGCTCAGGGAATCTTCCTCAACTTCAAGCGTCTTTTGGAGTTCAACCAGGGGAAGTTGCCATTTGCTGCTGCCCAGATCGGAAACTCCTTCAGGAATGAGATCTCGCCTCGCTCTGGCTTAATTCGTGTTAGAGAGTTTACAATGGCTGAGATCGAGCACTTTGTAGACCCCAATGAGAAGGTTCATTTCAAGTTCTCCAATGTGGCTGATCTGGATATCATGCTTTACTCTTCCAAAGCACAGACCAGTGGACAGTCTGCCCAGATAATGAGACTGGGTGATGCAGTGGAGCAGGGTGTCATCAACAACTCTGTCTTGGGCTACTTCATTGGAAGGATCTACCTTTATCTGGTTAAAGTTGGTGTGGCGAAAGACAAGCTGCGTTTCCGTCAGCACATGGACAATGAGATGGCCCACTACGCCTGTGACTGCTGGGATGCTGAGACCAAAACCTCTTATGGGTGGATCGAGATCGTAGGATGTGCTGATCGCTCATGTTATGATCTTCTGTGTCACGCACGTGCCACCAAAGTCCCTCTGGTTGCAGAGAAACCCCTAAAGGAACCCAAAGTTGTAAATGTTGTTCAGTTCGAGCCAAACAAAGGAGCCATCGGCAAAGCATATAAGAAGGATGCAAAGTTTGCGATGGAGTACCTGGCCATCTGCGATGAGTGCTATATCACAGAGCAGGAGAAACTGCTTAACGAGAATGGTGAGTTCACCATTGAGACTGAGGGCAAGACTTTCAAACTCACCAAGGACATGGTTAACATCAAAAGATTCCAGAAGACCCTGCATGTTGAGGAGGTGGTTCCTAATGTGATCGAACCCTCTTTCGGTATCGGGAGGATCATGTACTCAATCTTTGAGCACACATTCCGCATCAGGGAGGGTGACGAACAAAGAACGTATTTCAGCTTTCCTGCCACAGTTGCACCATACAAATGCTCCGTCCTTCCATTGAGCCAAAATCAGGAATTTATGCCGTTCGTTCGAGAATTATCTGAAGCCTTGACCAGGAATGGTGTCTCCCACAAGGTAGATGATTCATCAGGATCTATTGGCAGACGCTACGCCAGAACGGATGAGATTGGTGTGGCATTCGGTATCACCATTGATTTCGACACGGTTAATAAAAATCCCCACACAGCCACTCTGAGAGACCGCGACTCCATGAGACAGATCAGGGCTGAGGTTGGTGAGTTGCCTGAAATCATTCGTGACCTGGCCAATGGTGCCATCACTTGGGCAGAGGTGGAAAGCAAGTACCCAATCTTCGAAGGCCAGGAGACCAGCAAAAAGGAAACTGTGGAAGAGTAGATTGTCTGTTTGTCTAACTCATCCGCCTTTTTGTTGGAGGCAATCAAGGACATTTTTACTTTTGCATTCATAGGATCAAATTAATGGCAATTGTAACGTACAACCAGTAAATGTGCACCACATTTTCCACTCAGCTGGAACCACTGTAACCAAACGCCTCCTTTAAAAGTCAATGAAGCTCTAGAAGGACCTACAGTAAGATGACTGTAATTAGGTTTCCGTACTAGCAAAGGGATTTCACCATTCCTGTCCATGGATTGATAAATGAAGTTATGAATCTCACATATGGTCAAATAAATCAAACCAGCACTTTCTGGACCTATTAAA

Function

symbol description
gars1 Predicted to enable glycine-tRNA ligase activity. Acts upstream of or within translation. Predicted to be active in mitochondrion. Is expressed in several structures, including anterior neural keel; blood island; central nervous system; heart; and segmental plate. Used to study Charcot-Marie-Tooth disease type 2. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2D and distal hereditary motor neuronopathy type 5A. Orthologous to human GARS1 (glycyl-tRNA synthetase 1).

GO:

id name namespace
GO:0006412 translation biological_process
GO:0006418 tRNA aminoacylation for protein translation biological_process
GO:0006426 glycyl-tRNA aminoacylation biological_process
GO:0070150 mitochondrial glycyl-tRNA aminoacylation biological_process
GO:0005737 cytoplasm cellular_component
GO:0005739 mitochondrion cellular_component
GO:0004812 aminoacyl-tRNA ligase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0004820 glycine-tRNA ligase activity molecular_function
GO:0000166 nucleotide binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-030131-9174 Predicted to enable glycine-tRNA ligase activity. Acts upstream of or within translation. Predicted to be active in mitochondrion. Is expressed in several structures, including anterior neural keel; blood island; central nervous system; heart; and segmental plate. Used to study Charcot-Marie-Tooth disease type 2. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2D and distal hereditary motor neuronopathy type 5A. Orthologous to human GARS1 (glycyl-tRNA synthetase 1).

Ensembl:

ensembl_id ENSDARG00000059070

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00045528 True 2622 mRNA 0.47 17 20536056 20554969

Neighbor

gene id symbol gene type direction distance location
XLOC_022898 plcd1a coding upstream 116802 20372497 ~ 20419254 (+)
XLOC_022897 acaa1 coding upstream 203596 20325312 ~ 20332460 (+)
XLOC_022896 NA coding upstream 458760 20060772 ~ 20077296 (+)
XLOC_022895 NA coding upstream 481098 20054470 ~ 20054958 (+)
XLOC_022894 LIMD2 coding upstream 525233 19986432 ~ 20010823 (+)
XLOC_022900 hhatlb coding downstream 4040 20559009 ~ 20572170 (+)
XLOC_022901 klhl40b coding downstream 20290 20575259 ~ 20581672 (+)
XLOC_022902 sec22c coding downstream 103791 20658760 ~ 20675426 (+)
XLOC_022903 CR931724.1 coding downstream 233199 20788168 ~ 20788284 (+)
XLOC_022904 NA coding downstream 361776 20916745 ~ 20918412 (+)
XLOC_022892 NA non-coding upstream 820832 19704715 ~ 19715224 (+)
XLOC_022891 NA non-coding upstream 838610 19591878 ~ 19697446 (+)
XLOC_022887 NA non-coding upstream 1657076 18876733 ~ 18878980 (+)
XLOC_022912 CU915780.1 non-coding downstream 717643 21272612 ~ 21272728 (+)
XLOC_022913 NA non-coding downstream 752598 21307567 ~ 21308014 (+)
XLOC_022915 AL929009.1 non-coding downstream 946890 21501859 ~ 21502569 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
eurasian perch (Perca fluviatilis) G88658 NA non-coding NC_053119.1 CM020916.1 28983221 ~ 28983505 (+)