XLOC_022901 (klhl40b)


Basic Information

Item Value
gene id XLOC_022901
gene name klhl40b
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007135.7
NCBI id CM002908.2
chromosome length 42172926
location 20575259 ~ 20581672 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00045530
CATTCATTGACTTCAGTGGGACACTAAGGGATTGAAGACAGTCAGCATGGCTCTACCCATAGACCCAATGGAGGAGCCGCGAATGTACCAGCAAACCTTGCTGCAGGACGGCCTGTATGATCTTCTGGAGAGTGATATGATGGTTGATTGTGTGTTGAAGATAAAAGACAAGGAGTTTCCCTGCCACCGGTTGGTCCTGGCGGCCTGCAGCTCCTACTTCAGAGCTTTCTTCAAATCAGGTGTGGAGGAGAGCAAACAGCGAGAGATTGTTTTGGAGGACGTGGAGCCTGGAGTCATGGGAATTATCCTGAAGTACCTCTACACCTCCAACATCAATGTGACAGAGCAAAACGTTCAGGACATCTTCGCCTTGTCTAACATGCTTCAGATCCCGTCAATATTCACTGTATGTGTCTCGTTCCTGCAAAAGCGCCTGAGTTTGAGCAACTGCTTAGCCATTTTTAGATTAGGCCTGATGTTGGATTGTCCTCGTCTTGCCATATCGGCGAGGAACTTTGCTTGCGAGCGCTTTCAGTTTATTACTCGGGATGAGGAATTCCTGCAGCTGACTCCAAGCGAATTGGCGGCAGTTTTGGCATCAGACTCTTTGAACGTAGAGACGGAGCAGGATGTTTTTGAGGCTTTGATCAAGTGGGTTGGACATGACCAAGAGAACAGAATTGGGGACTTACCAGATCTGCTGGACTGCATCAGGCTACGTCTGGTTCCTCGGGACTACTTTGTCAAAAATGTGGAGAAACATGAGTGGTTGAGCTCGAATCCTGAGATCACTAAGAAACTCCAACTGGTCAAAGATGCCCATGCGGGGAAGCTTCCGGAACTCaagaaaaccaaaaacaaaaagagTCCTAGTGAGGAAGGACAGAAGAAGGGAGATGaagaggaggtggaggaggaggaagagcagGAAGAGCGACTTCCAGGAATCTTGAATGACAACCTGCGGTTCGGGATGTTCTTGAGAGAGTTGATCTTTTTGATCAATGACTCTGCATCGGTGGCTTATGACCCAACAGGAAATGATTGTTATGTGGCATCGGTCTCAACTCAAATTCCCAAAAACCATTGCAGTCTGGTCACAAAGGAAAACCAGATATTTGTGGCAGGTGGACTCTTTTTTgatgagcagagcaaagatgaacagatttactcatactttttacaGTTCGACCCTGCATCGTCTGACTGGATGGGAATGCCTCCAATACCCTCCCCTCGCTTCCTGTTTGGGATGGGTGAAGCCGAAAACTTCATCTTTGTAATTGGAGGAAGAGAAATGAAGGAAGGAGAAAACATTTTGAACACAGTTATGGTTTACGACAGACAGTTTCTTAAATGGGCTGAGTCAGATCCTCTTCCCTACCTAGTGTATGGCCATGGAGTTGTGTCTCATAATGAAATGATTTATGTAATCGGAGGAAAAGGAGAAAACAAAGAGTGTCTGAATCGGGTATGTGCTTATGACATTAAAACGCATCAATGGAAAGACCTTGCTCCATTAAACACAGCACGCTCGCTCTTCGGGGTCACAATCCACAAAAACAACATCTACGTGGTGGCTGGTGTTACTGACTCAGGCCTCACGGGCAGCGCTGAGGTCTATGACATCAAAACCAACAAgtgGTCAGAGTTTGTTGAGTTTCCTCAGGACCGCAGTTCTCTCAGTCTGGTCTCTGTCAGTGGGGTCCTCTATGCTGTGGGGGGATTTGCCATGTTTCCTAAAGAGGACAGTGATGATCTCATGCCACTGGAGATGAATGACATCTGGAGgtatgatgaAAGCGAGCGGACATGGAGCGGCATACTGAGGGAGAATCGATACGCATCTGGTGCAACAGTTCTGGGAGTTCGTCTTAACACTCTTCGCCTCACTAAAATGTAAA

Function

symbol description
klhl40b Acts upstream of or within skeletal muscle fiber development and swimming. Predicted to be located in cytoplasm. Predicted to be part of Cul3-RING ubiquitin ligase complex. Is expressed in eye; fin; skeletal muscle; and somite. Human ortholog(s) of this gene implicated in nemaline myopathy 8. Orthologous to human KLHL40 (kelch like family member 40).

GO:

id name namespace
GO:0048741 skeletal muscle fiber development biological_process
GO:0007275 multicellular organism development biological_process
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process biological_process
GO:0031397 negative regulation of protein ubiquitination biological_process
GO:0031398 positive regulation of protein ubiquitination biological_process
GO:0061061 muscle structure development biological_process
GO:0036268 swimming biological_process
GO:0098528 skeletal muscle fiber differentiation biological_process
GO:0031672 A band cellular_component
GO:0031674 I band cellular_component
GO:0031463 Cul3-RING ubiquitin ligase complex cellular_component
GO:0005737 cytoplasm cellular_component

KEGG: NA

ZFIN:

id description
ZDB-GENE-060227-1 Acts upstream of or within skeletal muscle fiber development and swimming. Predicted to be located in cytoplasm. Predicted to be part of Cul3-RING ubiquitin ligase complex. Is expressed in eye; fin; skeletal muscle; and somite. Human ortholog(s) of this gene implicated in nemaline myopathy 8. Orthologous to human KLHL40 (kelch like family member 40).

Ensembl:

ensembl_id ENSDARG00000019125

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00045530 True 1904 mRNA 0.47 6 20575259 20581672

Neighbor

gene id symbol gene type direction distance location
XLOC_022900 hhatlb coding upstream 3089 20559009 ~ 20572170 (+)
XLOC_022899 gars1 coding upstream 20290 20536056 ~ 20554969 (+)
XLOC_022898 plcd1a coding upstream 156005 20372497 ~ 20419254 (+)
XLOC_022897 acaa1 coding upstream 242799 20325312 ~ 20332460 (+)
XLOC_022896 NA coding upstream 497963 20060772 ~ 20077296 (+)
XLOC_022902 sec22c coding downstream 77088 20658760 ~ 20675426 (+)
XLOC_022903 CR931724.1 coding downstream 206496 20788168 ~ 20788284 (+)
XLOC_022904 NA coding downstream 335073 20916745 ~ 20918412 (+)
XLOC_022905 cst14a.2 coding downstream 338891 20920563 ~ 20921714 (+)
XLOC_022906 fam162a coding downstream 345463 20927135 ~ 20934666 (+)
XLOC_022895 NA non-coding upstream 520301 20054470 ~ 20054958 (+)
XLOC_022892 NA non-coding upstream 860035 19704715 ~ 19715224 (+)
XLOC_022891 NA non-coding upstream 877813 19591878 ~ 19697446 (+)
XLOC_022887 NA non-coding upstream 1696279 18876733 ~ 18878980 (+)
XLOC_022912 CU915780.1 non-coding downstream 690940 21272612 ~ 21272728 (+)
XLOC_022913 NA non-coding downstream 725895 21307567 ~ 21308014 (+)
XLOC_022915 AL929009.1 non-coding downstream 920187 21501859 ~ 21502569 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000018_04029960_04035673 KLHL40B, KLHL40 coding CI01000018 null 4029770 ~ 4035718 (+)