XLOC_023230 (fars2)


Basic Information

Item Value
gene id XLOC_023230
gene name fars2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007135.7
NCBI id CM002908.2
chromosome length 42172926
location 2557794 ~ 2736809 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00045980
AAACAAAGCTGTCAGTTCAGCGCAAGGACCCAAAACAACTGCGAGAGGCGCGCCTGAATGCACGCATACGCGCTGTAGAATTAAAATATGCAAGAAAGGCTGATTTCCGAGGTTAAGTGATAACCTGTCATTCATGAAGAAGCTATAATTAATAAAGTACACATGTTGAATCTTAATCAAAATGCGCTATGAGATGTTAGGATTTTATTGATCAGGCAGATCGGCGGTCGTCTCAAAAACAGCACGCGCGTCCTGACAGAGGCTTATGGACCAGCTACTATGCCATTATACAGTAGTTCCCGTACTGTGGTCCCACTCCTCAAACACATTATTCGTCACTGTCCTGCCAGAGTCTTCAGCGTGTCCCGCTGCCTGTCGACGGATGGCTCCGCTGCACAGCCACAGATTCAAGAAAACTCTGTTCAACTTTTCAACCATGTCTACCCACGAGACGACATGACCAATGTGACAGCTAAAATCTTGTCCAAAGTCGGCTGTCAGCTTCACAACCGGCCGCACCACCCCTTGTGGCTTATTAAAGAACGCATCAAAGACCATTTCTATCGCTCGTACGTGGGTCGCACTGGAAACCCCATCTTTTCTGTACATGACAACCTGAGGCCGGTAGTGACGGTGGAGCAGAACTTCGACAGCCTGCTCATTCCTGCAGACCACCCCAGTCGCAAAAAAGGAGAGAATTATTACCTGAACCGCACACACATGCTGAGGGCGCACACCTCCGCCCATCAGAAAGAGCTGGTGCGCTCGGGCCTCGACTGCTTTCTGCTGGCCGGAGACGTTTACAGGAGAGATGAGGTCGATTCCAGCCACTATCCTGTCTTCCATCAGATGGAGGGAGTGCGGCTGTTCTCCAATCATGAGCTGTTTGCTGGAGTGGAGAATGGTGAAGATCTGTCTTTGTTTGAGCGTGGCGGTCGGCGAACGCCTCAAAAGCAGGAGACGCACACGCTGGAGGCCGTCAAACTGCTGGAGTTTGATCTGAAACGCGCTCTCACGCGCCTCGTGCGACACCTTTTCGGGGAAGATCTGGAGATCCGCTGGGTGGACTGTTACTTCCCCTTCACACATCCGTCCTTCGAGATGGAGGTGTTCTTTCAGGGGGACTGGATGGAGGTGCTGGGATGTGGAGTGATGGAGCAGGAGCTGGTGCGCTCAGCTGGTGCTGATAATAAGATGGGCTGGGCGTTTGGTCTGGGGCTGGAGAGATTGGCCATGGTTCTGTTCGGTATCCCGGATATCCGGCTTTTCTGGAGCGAGGATGAACGCTTCCTGAAGCAGTTTCGCCTGTCTGACATCTATCAGCCTGTCACATTCCAGCCTCTCAGCAAGTATCCTCCGCTCTTCAATGACATCTCTTTTTGGCTGCCGGCCGAAGGTTACACAGAAAACGACTTCTACGACCTGGTCCGCAGCATCGGAGGAGACTTGGTGGAGAAGGTCACGCTGGTGGACACGTTCACACATCCAAAGATGAAGAAAGTGAGCCACTGTTACCGTCTTGTGTACCGTCACATGGAAAGGACTCTGACTCAAGAAGAAGTGAGCATCGTCCACACTGCCATCCAGACAGCGGTGGAGCAGGAGCTGGGCGTGCAGGGCAGATTCTGATGTGTTTACACACATCAGCGTCACCAGGTTTCTCTAACTAATTAAATGTGGAAACTCTTCAACTGCACTCAGCTGGAGACTCCCTCTGTAGTTTCTTAAAGGAACACGGCATAACTCAGCAAAACTACAAATAGTCATATTATTTAGTCAtcatcttgtgtttttttttttcaatctacaACATCACTAAAGTAATAGTTTAGGCTACAGTTCAAATCTTTTCAGTCTCAGTgaaacacaaattaatatatttttctagTCATTTGGTGACCCTTGACTTTGAATGGGCTAGTGTGAGTTTAGCATCACTGAGATActgctacactctaaaaaatgctgtttaTAGAGTGTATACaaggttcattttttttttataaatgcttGGTTGTTGTATAACCCAACAGATGGGTTAtaaaattttacttaaattaaatttttaacattAT

Function

symbol description
fars2 Predicted to enable phenylalanine-tRNA ligase activity. Predicted to be involved in phenylalanyl-tRNA aminoacylation. Predicted to act upstream of or within tRNA aminoacylation and translation. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 14 and hereditary spastic paraplegia 77. Orthologous to human FARS2 (phenylalanyl-tRNA synthetase 2, mitochondrial).

GO:

id name namespace
GO:0043039 tRNA aminoacylation biological_process
GO:0006432 phenylalanyl-tRNA aminoacylation biological_process
GO:0005737 cytoplasm cellular_component
GO:0005739 mitochondrion cellular_component
GO:0000049 tRNA binding molecular_function
GO:0004812 aminoacyl-tRNA ligase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0004826 phenylalanine-tRNA ligase activity molecular_function
GO:0000166 nucleotide binding molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-070928-38 Predicted to enable phenylalanine-tRNA ligase activity. Predicted to be involved in phenylalanyl-tRNA aminoacylation. Predicted to act upstream of or within tRNA aminoacylation and translation. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 14 and hereditary spastic paraplegia 77. Orthologous to human FARS2 (phenylalanyl-tRNA synthetase 2, mitochondrial).

Ensembl:

ensembl_id ENSDARG00000091247

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00045980 True 2075 mRNA 0.48 7 2557794 2736809

Neighbor

gene id symbol gene type direction distance location
XLOC_023229 ly86 coding downstream 90127 2460178 ~ 2467667 (-)
XLOC_023228 rreb1a coding downstream 107197 2346514 ~ 2450597 (-)
XLOC_023227 cul2 coding downstream 214428 2283959 ~ 2343366 (-)
XLOC_023226 PARD3 coding downstream 572787 1845689 ~ 1985007 (-)
XLOC_023225 CABZ01067348.1 coding downstream 719972 1673250 ~ 1837822 (-)
XLOC_023232 NA coding upstream 25911 2762720 ~ 2821784 (-)
XLOC_023233 NA coding upstream 89401 2826210 ~ 2829208 (-)
XLOC_023234 cyb5a coding upstream 99498 2836307 ~ 2843107 (-)
XLOC_023235 dipk1c coding upstream 152526 2889335 ~ 2917540 (-)
XLOC_023236 BX897669.1 coding upstream 182596 2919405 ~ 2919521 (-)
XLOC_023665 dre-mir-735 misc upstream 35441152 38177961 ~ 38178027 (-)
XLOC_023223 NA non-coding downstream 937831 1462219 ~ 1619963 (-)
XLOC_023220 NA non-coding downstream 1448349 1033429 ~ 1109445 (-)
XLOC_023218 BX005461.4 non-coding downstream 1563664 994016 ~ 994130 (-)
XLOC_023216 BX005461.3 non-coding downstream 1594752 961874 ~ 963042 (-)
XLOC_023243 NA non-coding upstream 744584 3481393 ~ 3487660 (-)
XLOC_023244 AL954666.1 non-coding upstream 772568 3509377 ~ 3534690 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000070_03509506_03553420 FARS2 coding CI01000070 null 3509506 ~ 3553728 (+)
bowfin (Amia calva) AMCG00019767 fars2,LOC103399687 coding CM030124.1 CM030124.1 43702543 ~ 43705085 (+)