XLOC_002462 (gnsb)


Basic Information

Item Value
gene id XLOC_002462
gene name gnsb
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007121.7
NCBI id CM002894.2
chromosome length 45420867
location 45031398 ~ 45047242 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00004620
AGCGCGTGTCTCCGCCGTGACTGTCCGCTTCTGCTCGACTCTCCAGCGGCTGCTCCGGCTCTGAGTGTCCGCAATGAGGAGCTCTCCGCCCGGTCAGTGGAGCTGCGGCTGCCCGCTGAAGCTGCTGgtgcttttcttcttcttctttaccTGCGCTTTCAGCAGCAAAAACAACATCATCCTCATCCTCACCGACGACCAGGACGAGCAGATGGGCGGAATGACGCCGATGAAGAAGACGAGAGAGCTGATTGGTGACGCCGGCGCGACCTTCTCTAACGCTttcacCTCCACGCCGCTGTGCTGTCCGAGCCGCAGCAGCTTCCTGAGCGGCAGATATCCACACAATCATCTGGTGCACAATAACTCAGTGGAGGGAAACTGCAGCAGCGCCGCCTGGCAGAAAACAGCCGAGCCCTTCGCCTTCCCCGTTTACCTCAACAAGATGCGCTACCAGACCTTCTACTGCGGTAAATACCTCAACCAGtatgGCAGTAAAGACGCTGGCGGTGTTGCTCATGTGCCTCCTGGATGGGATCAGTGGCATGCGCTGGTGGGAAACTCTAAATATTATAACTACACTCTGTCAGTGAATGGGAAAGAGGAAAAGCATGGAGACAGCTATGAGAAGGATTATCTCACAGACCTGGTGCTGAACCGCTCTCTGCATTTCCTGGAGGAGCGCAGTCCCAGTCACCCGTTCTTCATGATGTTGTGTCCACCGGCTCCTCACTCTCCGTGGACCGCCGCTCCACAGTACAGCGGCTCCTTCAGCGGCGTTAAAGCTCCGCGCAACGGCAGCTTCAACAAACCTGGaacgGACAAGCATTGGTTACTACGGCAACCTGCCAATCCAATGCCGAACAGCTCTATTGATTACCTTGACAACGCTTTCCGCAGAAGatggCAGACTCTTCTGTCTGTGGATGATCTGGTGGAGCGTCTGCTGAAGAAGCTGGATTCAGTGAAGGAGCTCGACAACACATACATCTTCTACACGTCTGACCACGGATATCACACCGGTCAGTTCTCGTTACCCATTGACAAAAGGCAGCTGTATGAGTTCGACATCCGCATTCCTCTGCTGGTTCGGGGTCCAGGAATCAAAGCCAAACAAACACTTCAGtCTCCAGTGCTGAATATTGATCTCCCGATGACGATCCTGGACATCGCTGGAGTCAATCTGTCCACCGTCAACATGGACGGACAGTCCTTCCTGCCGCAGATGgcccCGTCCCTGCGTAACGGCACCGAGCGGCCCTTCTTCCTGGTGGAGTACACGGGTGAGGGATACTCGTCTCAGGACCCCAGTTGCCCCAAACTGGGCCCCGGCCTCGCTGAGTGTTTtccagactgtgtgtgtgaagACGCCTTTAACAACACCTACGCCTGCGTCAGGACGCTCAAAGGCGCAAACCTGCAGTACTGCGAGTTCGCCGACAATGAGgCGTTTGTGGAGATGTACAACCTGACGGCAGATCCTCATCAGCTGGAGAACATTGTGAAGAAAGTAGATCCGTCACTGCTGCAGATCATGAACCAGCGGCTGATTAAACTACAGTCCTGCGCTGGAGACACCTGCAGAAACatcagatgaggatgatgatgatgaataccGCAGGCAAACCTCACATACAAATCAAGATCTGCTGctttattcatacacacacacacacacacacacaacaacaacacacacaaacacacacacacacacacactcatacacactcagagaaaacaacaacaatgatccgctttggttttattttggtaatatgCTCATGTTAAACTCTCCTGCAAGTAAACAGGTACTTTTAACCATGTTTTGAATACATTCACCAGAACTCTGGGTCTagcaggaacacttttagcttagcttagcatagatcattgaattgtattagaccattagcatctcactcaaaaaaaaa

Function

symbol description
gnsb Predicted to enable N-acetylglucosamine-6-sulfatase activity and glycosaminoglycan binding activity. Predicted to act upstream of or within glycosaminoglycan metabolic process. Predicted to be located in lysosome. Is expressed in pronephric duct and yolk syncytial layer. Human ortholog(s) of this gene implicated in mucopolysaccharidosis III and mucopolysaccharidosis type IIID. Orthologous to human GNS (glucosamine (N-acetyl)-6-sulfatase).

GO:

id name namespace
GO:0030203 glycosaminoglycan metabolic process biological_process
GO:0005764 lysosome cellular_component
GO:0008449 N-acetylglucosamine-6-sulfatase activity molecular_function
GO:0046872 metal ion binding molecular_function
GO:0005539 glycosaminoglycan binding molecular_function
GO:0008484 sulfuric ester hydrolase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0003824 catalytic activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-030131-5846 Predicted to enable N-acetylglucosamine-6-sulfatase activity and glycosaminoglycan binding activity. Predicted to act upstream of or within glycosaminoglycan metabolic process. Predicted to be located in lysosome. Is expressed in pronephric duct and yolk syncytial layer. Human ortholog(s) of this gene implicated in mucopolysaccharidosis III and mucopolysaccharidosis type IIID. Orthologous to human GNS (glucosamine (N-acetyl)-6-sulfatase).

Ensembl:

ensembl_id ENSDARG00000098296

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00004620 True 1934 mRNA 0.52 13 45031398 45047242

Neighbor

gene id symbol gene type direction distance location
XLOC_002461 h2az2b coding upstream 32946 44984946 ~ 44998452 (+)
XLOC_002460 il1b coding upstream 66622 44955106 ~ 44964776 (+)
XLOC_002459 cnnm4a coding upstream 89167 44940693 ~ 44942231 (+)
XLOC_002458 sec14l7 coding upstream 91740 44924684 ~ 44939658 (+)
XLOC_002457 NA coding upstream 113999 44913607 ~ 44917399 (+)
XLOC_002463 nudcd3 coding downstream 12460 45059702 ~ 45070182 (+)
XLOC_002464 camk2b2 coding downstream 24361 45071603 ~ 45134581 (+)
XLOC_002465 NA coding downstream 93702 45140944 ~ 45145137 (+)
XLOC_002466 ogdhb coding downstream 100763 45148005 ~ 45205893 (+)
XLOC_002467 CT956056.1 coding downstream 190714 45237956 ~ 45238042 (+)
XLOC_002456 BX569788.2 non-coding upstream 123515 44907768 ~ 44907883 (+)
XLOC_002453 BX569788.1 non-coding upstream 261877 44767388 ~ 44769521 (+)
XLOC_002447 NA non-coding upstream 647939 44380982 ~ 44383459 (+)
XLOC_002445 NA non-coding upstream 833187 44055749 ~ 44198211 (+)
XLOC_002470 NA non-coding downstream 308461 45355703 ~ 45356324 (+)

Expression


Co-expression Network