XLOC_025208 (dhx58)


Basic Information

Item Value
gene id XLOC_025208
gene name dhx58
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007114.7
NCBI id CM002887.2
chromosome length 62628489
location 17689419 ~ 17710221 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00049780
ATGGAGCTCAGACTCAGGCCATATCAGGAGGAGGTGGTCCAGGCGGCTTTAAGAGGAGAGAACAGCATCATCTGGCTGCCCACTGGTGGAGGAAAAACTCGTGCTGCGGTTTACGTCGCTGAGAAACATCTAGAGACCAAAGCCAATGCCAAAGTTGCAGTGCTCGTCAATAAGGTGCACCTGGTAGACCAGCACTATATGAAAGAATTTGGCCATTACCTAAGGCACAAATACAGGATAAAGGCCATCAGTGGTGACAGCAGTGAGAAAGACTTTTTTGGGCGTCTTGTTAGAGTCTCAGACTTGGTCATCTGCACGGCTCAGATTCTGGAAAACGCCTTGAACAACATGGATGAGGACAAGCACGTGGAGATCACTGACTTTACCCTACTGGTCATAGATGAATGTCATCACACAAACAAGGAGAGTGTCTATAACAAAATTATGTGGCGTTACGTGGAGAAGAAAGTGAGAAAAGAAGGCAGACTGCCTCAGATTTTGGGCCTCACAGCATCACCTGGTACAGGAGGAAACAAGTCATTAGATAAAGCTGTTGAACACGTCCTGCAGATCTGTGCCAATCTGGATTCAAAAATTGTGTCCACCAAGAATTACACGCCGATGCTGCAGAACTTTGTCCCAAAACCCAAAAAGGAATATGACATTGTCGAAAGAAGAGATAAAGATCCATTTGGTGACCACTTAAAGTCAATGATGTTAATGATTCATGAGTTTATGCCACCAACGGTGAGTCGCGGCCTGCGAGAACTAGGCACCCAGGAATATGAGGctgatgtggtggaactggagaaaGCAGGTGTAAAAGTAAACAACAGACTGATCGCTCAGTGTGCTTTGCATCTACGTAAATACAACGATGCCCTTCTCATTAATGACACCATTCGCATGGTGGATGCGTTCAGAGTGCTGGAAGAGTTTTACAATTCAAGAAGCAGCAAGTTGCTGGATGGAACAGACATCTTTCTACAAGGACTTTTCGATGAGAACAGTCTGGAGTTAAAACATCTGGCGTCGGACGCCCGATATGAAAACCCCAAACTGGCTCAACTGCAGAGCAGATTGCTGGAAGAGTTCCAAGACACTAATTCTCGTGGAATCATCTTCTCAAAGACACGCAGAGGCACGCATTGTCTGAATGACTGGGTGAAAACAAACCGTGAGCTGCAGAGGGTCAACATCACTGCTGGCATTCTGACCGGAGCCGGTAATGGCGCTAACAACATGACACAGACTGAACAGAAGAGCGTCATCAGTCATTTTAGGCAAGGATACCTCAACCTCCTCATCTCCACCAGTGTAGCTGAGGAAGGACTGGATATTCCTGAATGCAACTTAGTTGTGCGTTACGGGCTGTTGACCAATGAAATCGCTCAGCAGCAGGCCAGCGGACGAGCTCGAGCCTCCAACAGTGTCTACTCTGTGGTGGCTGACGTAGGTGGACGGGAAGTGCGCAAAGAACTTGTCAATGAGTATCTAGAAGATCTCACCGCAAGAGCTATTGATGAAGTACAGCGCATGAGTCCTGTGGATTTCAGACACAAGGTTTGTGTTTGA
>TCONS_00049781
ATGGAGCTCAGACTCAGGCCATATCAGGAGGAGGTGGTCCAGGCGGCTTTAAGAGGAGAGAACAGCATCATCTGGCTGCCCACTGGTGGAGGAAAAACTCGTGCTGCGGTTTACGTCGCTGAGAAACATCTAGAGACCAAAGCCAATGCCAAAGTTGCAGTGCTCGTCAATAAGGTGCACCTGGTAGACCAGCACTATATGAAAGAATTTGGCCATTACCTAAGGCACAAATACAGGATAAAGGCCATCAGTGGTGACAGCAGTGAGAAAGACTTTTTTGGGCGTCTTGTTAGAGTCTCAGACTTGGTCATCTGCACGGCTCAGATTCTGGAAAACGCCTTGAACAACATGGATGAGGACAAGCACGTGGAGATCACTGACTTTACCCTACTGGTCATAGATGAATGTCATCACACAAACAAGGAGAGTGTCTATAACAAAATTATGTGGCGTTACGTGGAGAAGAAAGTGAGAAAAGAAGGCAGACTGCCTCAGATTTTGGGCCTCACAGCATCACCTGGTACAGGAGGAAACAAGTCATTAGATAAAGCTGTTGAACACGTCCTGCAGATCTGTGCCAATCTGGATTCAAAAATTGTGTCCACCAAGAATTACACGCCGATGCTGCAGAACTTTGTCCCAAAACCCAAAAAGGAATATGACATTGTCGAAAGAAGAGATAAAGATCCATTTGGTGACCACTTAAAGTCAATGATGTTAATGATTCATGAGTTTATGCCACCAACGGTGAGTCGCGGCCTGCGAGAACTAGGCACCCAGGAATATGAGGctgatgtggtggaactggagaaaGCAGGTGTAAAAGTAAACAACAGACTGATCGCTCAGTGTGCTTTGCATCTACGTAAATACAACGATGCCCTTCTCATTAATGACACCATTCGCATGGTGGATGCGTTCAGAGTGCTGGAAGAGTTTTACAATTCAAGAAGCAGCAAGTTGCTGGATGGAACAGACATCTTTCTACAAGGACTTTTCGATGAGAACAGTCTGGAGTTAAAACATCTGGCGTCGGACGCCCGATATGAAAACCCCAAACTGGCTCAACTGCAGAGCAGATTGCTGGAAGAGTTCCAAGACACTAATTCTCGTGGAATCATCTTCTCAAAGACACGCAGAGGCACGCATTGTCTGAATGACTGGGTGAAAACAAACCGTGAGCTGCAGAGGGTCAACATCACTGCTGGCATTCTGACCGGAGCCGGTAATGGCGCTAACAACATGACACAGACTGAACAGAAGAGCGTCATCAGTCATTTTAGGCAAGGATACCTCAACCTCCTCATCTCCACCAGTGTAGCTGAGGAAGGACTGGATATTCCTGAATGCAACTTAGTTGTGCGTTACGGGCTGTTGACCAATGAAATCGCTCAGCAGCAGGCCAGCGGACGAGCTCGAGCCTCCAACAGTGTCTACTCTGTGGTGGCTGACGTAGGTGGACGGGAAGTGCGCAAAGAACTTGTCAATGAGTATCTAGAAGATCTCACCGCAAGAGCTATTGATGAAGTACAGCGCATGAGTCCTGTGGATTTCAGACACAAGGTGTTTGAGCTCCAGAAAACAGCTGTGGTGATTCGGATGGAGGCTGAACGGAAGAGGGATGCGAAAAAGCAGCGCTATAGTCCAGGTCAGGTTCAGCTTCAGTGCAGAAGCTGCTTCGCTTCCGTCTGCAGCGGAGGAGACATCAGGAAGATCGAGAACTCGCACCATGTCAACGTTAACACTGAGTTTAAaaaTCACTATAAAGTTGGTGACCAGGTGAATATGGAGAGGACCTTTGAAGACTGGGAGCCTGGACGGATTATCAGCTGcagaaaatgtaaaaagGACTGGGGATTCGAGATTAAATTCAAGAAAGTGGCAATTCTCCCCTGTCTGAAAATAAAGAGCTTCTCCTTTAACACCCCTAAAGAAACAAAGCCTTACAAGAAGTGGAAGGATGTTGAGTTTCAGGTGACAGAGTTTGACTTTATTGAGTACATGAGCTGCCGTTTCCCTGACCTGGACTTGTCTGACTGA

Function

symbol description
dhx58 Predicted to enable double-stranded RNA binding activity; single-stranded RNA binding activity; and zinc ion binding activity. Predicted to be involved in innate immune response; positive regulation of interferon-beta production; and response to virus. Predicted to act upstream of or within defense response to virus. Predicted to be active in cytoplasm. Orthologous to human DHX58 (DExH-box helicase 58).

GO:

id name namespace
GO:0045087 innate immune response biological_process
GO:0009615 response to virus biological_process
GO:0032728 positive regulation of interferon-beta production biological_process
GO:0005737 cytoplasm cellular_component
GO:0005524 ATP binding molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0003677 DNA binding molecular_function
GO:0000166 nucleotide binding molecular_function
GO:0003725 double-stranded RNA binding molecular_function
GO:0003727 single-stranded RNA binding molecular_function
GO:0008270 zinc ion binding molecular_function
GO:0004386 helicase activity molecular_function

KEGG:

id description
ko04622 RIG-I-like receptor signaling pathway
ko04054 Pattern recognition receptors

ZFIN:

id description
ZDB-GENE-120612-3 Predicted to enable double-stranded RNA binding activity; single-stranded RNA binding activity; and zinc ion binding activity. Predicted to be involved in innate immune response; positive regulation of interferon-beta production; and response to virus. Predicted to act upstream of or within defense response to virus. Predicted to be active in cytoplasm. Orthologous to human DHX58 (DExH-box helicase 58).

Ensembl:

ensembl_id ENSDARG00000089463

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00049780 False 1575 mRNA 0.47 8 17689419 17702622
TCONS_00049781 True 2040 mRNA 0.47 11 17689419 17710221

Neighbor

gene id symbol gene type direction distance location
XLOC_025207 kat2a coding upstream 9305 17653784 ~ 17680114 (+)
XLOC_025206 rab5c coding upstream 37520 17615599 ~ 17651899 (+)
XLOC_025205 kcnh4a coding upstream 85310 17547532 ~ 17604109 (+)
XLOC_025204 hcrt coding upstream 147971 17537352 ~ 17541448 (+)
XLOC_025202 si:ch211-210g13.5 coding upstream 166337 17346502 ~ 17523082 (+)
XLOC_025209 znf385c coding downstream 34118 17744339 ~ 17860047 (+)
XLOC_025210 BX901973.1 coding downstream 145760 17855981 ~ 17879354 (+)
XLOC_025211 dnajc7 coding downstream 167903 17878124 ~ 17910375 (+)
XLOC_025212 ttc25 coding downstream 200348 17910569 ~ 17928233 (+)
XLOC_025213 cnp coding downstream 222911 17933132 ~ 17946949 (+)
XLOC_025429 BX649540.1 misc downstream 12538518 30248739 ~ 30249036 (+)
XLOC_025203 CU207238.1 non-coding upstream 227534 17395239 ~ 17461885 (+)
XLOC_025197 BX470185.1 non-coding upstream 806115 16874401 ~ 16883304 (+)
XLOC_025188 CR388224.1 non-coding upstream 1316292 16373012 ~ 16373127 (+)
XLOC_025185 NA non-coding upstream 1448079 16186593 ~ 16241340 (+)
XLOC_025184 NA non-coding upstream 1527960 16153224 ~ 16161459 (+)
XLOC_025215 NA non-coding downstream 330392 18040613 ~ 18061783 (+)
XLOC_025218 NA non-coding downstream 479388 18189609 ~ 18197126 (+)
XLOC_025227 NA non-coding downstream 960603 18670824 ~ 18672291 (+)
XLOC_025229 AL772362.2 non-coding downstream 1061307 18771528 ~ 18788485 (+)
XLOC_025233 AL772362.1 non-coding downstream 1157614 18867835 ~ 18867952 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000034_05419465_05426380 NA coding CI01000034 null 5418660 ~ 5426380 (-)